Hans Jürgen Hoffmann

Current practice of allergy diagnosis and the potential impact of regulation in Europe

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review


  • Victoria Cardona
  • ,
  • Pascal Demoly, Département de Pneumologie et Addictologie, Hôpital Arnaud de Villeneuve, CHRU de Montpellier, and Sorbonnes Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, F-75013, Paris, France.
  • ,
  • Sten Dreborg, Section on Child and Adolescent Allergology, Women's and Children's Health, Academic Hospital, University of Uppsala, Uppsala, Sweden.
  • ,
  • A Fusun Kalpaklioglu, Department of Immunology and Allergic Diseases, Kirikkale University Hospital, Turkey.
  • ,
  • Ludger Klimek, Centre for Rhinology and Allergology, Wiesbaden, Germany.
  • ,
  • Antonella Muraro, Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy.
  • ,
  • Oliver Pfaar, Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Centre for Rhinology and Allergology, Wiesbaden, Germany.
  • ,
  • Todor A Popov, Clinic of Allergy and Asthma, Medical University, Sofia, Bulgaria.
  • ,
  • Hans Jürgen Hoffmann

In the European Union (EU), the regulatory framework regarding diagnostic allergen extracts is currently in the process of being implemented at the national level. Due to these regulations, the initial and periodic renewal expenses for the registration of diagnostic allergen extracts may render extract production unprofitable. Consequently, many extracts may be at risk of removal from the market. The current survey, which was conducted by a task force of the European Academy of Allergy and Clinical Immunology, aimed to assess the current practice of allergy diagnosis in Europe. This survey revealed that skin tests continue to be the main diagnostic procedure and are used as the first option in almost 2/3 of all types of allergic diseases and in 90% of individuals suffering from respiratory allergies. Therefore, there is a need to ensure the availability of high-quality allergen extracts to maintain the common diagnostic procedures used by EU professionals. To reach this goal, it is necessary to align efforts and establish active partnerships between manufacturers, relevant scientific societies, consumer organizations and authorities to maintain the availability of these diagnostic tools. This article is protected by copyright. All rights reserved.

Original languageEnglish
JournalAllergy: European Journal of Allergy and Clinical Immunology
Publication statusPublished - 2018

    Research areas

  • Journal Article

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