Projects per year
Personal profile
Research
I am a biomedical scientist specializing in chronic kidney and liver disease. In the past decade my research endeavours revolved around chronic kidney disease (CKD), metabolic-associated fatty liver disease (MAFLD) and organ fibrosis. As such, I established new translational disease models using (human) precision-cut tissue slices. Currently, I am studying the inter-organ signalling networks that link various cardiometabolic diseases.
Areas of expertise
- Fibrosis
- Chronic kidney disease
- Fatty liver disease
- Human tissue-based models
- Inter-organ communication
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Collaborations and top research areas from the last five years
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Projects
- 1 Active
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The Power of the Model – Designing Ethically Acceptable Futures of Human-Based Models in Translational Science
Høybye, M. T. (PI), Nørregaard, R. (CoPI), Mutsaers, H. A. M. (Collaborator), Paldam, E. (Collaborator), Skydsgaard, M. A. (Collaborator), Welsh, G. (Collaborator) & Leuvenink, H. (Collaborator)
01/07/2025 → 31/12/2027
Project: Research
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A human tissue-based model of renal inflammation
Merrild, C., Pedersen, G. A., Antonsen, K. W., Madsen, M. G., Keller, A. K., Møller, H. J., Nejsum, L. N., Mutsaers, H. A. M. & Nørregaard, R., 1 Nov 2024, In: Experimental Cell Research. 443, 1, 114309.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
An animal-free preclinical drug screening platform based on human precision-cut kidney slices
Mutsaers, H. A. M., Jensen, M. S., Kresse, J.-C., Tingskov, S. J., Madsen, M. G. & Nørregaard, R., Dec 2023, In: BMC Research Notes. 16, 1, 6 p., 39.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access3 Citations (Scopus) -
Obstructive nephropathy and molecular pathophysiology of renal interstitial fibrosis
Nørregaard, R., Mutsaers, H. A. M., Frøkiær, J. & Kwon, T. H., Oct 2023, In: Physiological Reviews. 103, 4, p. 2827-2872 46 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Open AccessFile86 Citations (Scopus)90 Downloads (Pure) -
Standardized Protocol for the Preparation of Precision-Cut Kidney Slices: A Translational Model of Renal Fibrosis
Jensen, M. S., Merrild, C., Nørregaard, R., Olinga, P. & Mutsaers, H. A. M., 2023, In: Methods in molecular biology (Clifton, N.J.). 2664, p. 123-134 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
1 Citation (Scopus) -
The impact of fibrotic diseases on global mortality from 1990 to 2019
Mutsaers, H. A. M., Merrild, C., Nørregaard, R. & Plana-Ripoll, O., Nov 2023, In: Journal of Translational Medicine. 21, 1, 818.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review
Open Access28 Citations (Scopus)