Jakob Grove

2025

Familial confounding in the associations between maternal health and autism

Khachadourian, V., Arildskov, E. S., Grove, J., O'Reilly, P. F., Buxbaum, J. D., Reichenberg, A., Sandin, S., Croen, L. A., Schendel, D., Hansen, S. N. & Janecka, M., Mar 2025, In: Nature Medicine. 31, 3, p. 996-1007 12 p.

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Open Access

1 Citation (Scopus)

Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses

Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., Polderman, T. J. C., Autism Spectrum Working Group of the Psychiatric Genomics Consortium & Demontis, D., 9 May 2025, (E-pub / Early view) In: JAMA Psychiatry. e0243639.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D. & Bäckman, J. & 32 others, Banaj, N., Barlassina, C., Nissen, J. B., Bienvenu, O. J., Black, D., Bloch, M. H., Børte, S., Bosch, R., Breen, M., Brennan, B. P., Brentani, H., Buxbaum, J. D., Bybjerg-Grauholm, J., Byrne, E. M., Cabana-Dominguez, J., Camarena, B., Camarena, A., Cappi, C., Carracedo, A., Casas, M., Grove, J., Meier, S., Wang, Y., Mortensen, P. B., Stein, D. J., Børglum, A. D., Hansen, B. K., Mors, O., Wagner, M., Mattheisen, M., Estonian Biobank & 23andMe Inc, 2025, (E-pub / Early view) In: Nature Genetics. 230.

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Open Access

Genome-wide association studies of binge eating behaviour and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes

Eating Disorders Working Group of the Psychiatric Genomics Consortium, Estonian Biobank (EstBB), 8 May 2025.

Research output: Working paper/Preprint › Preprint

Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders

Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., PGC TS Working Group & 23andMe Research Team, 1 Apr 2025, In: Biological Psychiatry. 97, 7, p. 743-752 10 p.

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Open Access

2 Citations (Scopus)

Genomics yields biological and phenotypic insights into bipolar disorder

23andMe Research Team, 27 Mar 2025, In: Nature. 639, p. 968-975 8 p., 2417.

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21 Citations (Scopus)

Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M., Apr 2025, (E-pub / Early view) In: Molecular Psychiatry. e1004092.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

APEX consortium & Mortensen, P. B., 24 Feb 2025, (E-pub / Early view) In: Molecular Psychiatry. 2301.

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The Digital Health Competencies in Medical Education Framework: An International Consensus Statement Based on a Delphi Study

Car, J., Ong, Q. C., Erlikh Fox, T., Leightley, D., Kemp, S. J., Švab, I., Tsoi, K. K. F., Sam, A. H., Kent, F. M., Hertelendy, A. J., Longhurst, C. A., Powell, J., Hamdy, H., Nguyen, H. V. Q., Aoun Bahous, S., Wang, M., Baumgartner, M., Mahendradhata, Y., Popovic, N. & Khong, A. W. H. & 3 others, Prober, C. G., Atun, R. & Digital Health Systems Collaborative, 2 Jan 2025, In: JAMA network open. 8, 1, e2453131.

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Open Access

5 Citations (Scopus)

The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder

Christiansen, G. B., Petersen, L. V., Chatwin, H., Yilmaz, Z., Schendel, D., Bulik, C. M., Grove, J., Brikell, I., Semark, B. D., Holde, K., Abdulkadir, M., Hübel, C., Albiñana, C., Vilhjálmsson, B. J., Børglum, A. D., Demontis, D., Mortensen, P. B. & Larsen, J. T., May 2025, In: Molecular Psychiatry. 30, 5, p. 2127-2136 10 p., 132.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

1 Citation (Scopus)

2024

Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology

Montalbano, S., Krebs, M. D., Rosengren, A., Vaez, M., Hellberg, K. L. G., Mortensen, P. B., Børglum, A. D., Geschwind, D. H., Raznahan, A., Thompson, W. K., Helenius, D., Werge, T., Ingason, A. & iPSYCH Investigators, Dec 2024, In: npj Genomic Medicine. 9, 1, 67.

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Open Access

Exploring the Genetic Risk of Childhood Daytime Urinary Incontinence: A Genome-Wide Association Study

Breinbjerg, A., Jørgensen, C. S., Walters, G. B., Grove, J., Als, T. D., Kamperis, K., Stéfansdóttir, L., Thirstrup, J. P., Borg, B., Albiñana, C., Vilhjálmsson, B. J., Eðvarðsson, V. Ö., Stefánsson, H., Mortensen, P. B., Agerbo, E., Werge, T., Børglum, A., Demontis, D., Stefánsson, K. & Rittig, S. & 1 others, Christensen, J. H., 1 Dec 2024, In: The Journal of Urology. 212, 6, p. 851-861 11 p.

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2 Citations (Scopus)

Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci

23andMe Research Team, 13 Mar 2024.

Research output: Working paper/Preprint › Preprint

Open Access

Method for Testing Etiologic Heterogeneity Among Non-Competing Diagnoses, Applied to Impact of Perinatal Exposures on Autism and Attention Deficit Hyperactivity Disorder

Kalkbrenner, A. E., Zheng, C., Yu, J., Jenson, T. E., Kuhlwein, T., Ladd-Acosta, C., Grove, J. & Schendel, D., 1 Sept 2024, In: Epidemiology. 35, 5, p. 689-700 12 p., 1760.

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Open Access

Phenotypic and ancestry-related assortative mating in autism

iPSYCH Consortium, Jun 2024, In: Molecular Autism. 15, 1, p. 27 1 p., 27.

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Open Access

Polygenic risk of mental disorders and subject-specific school grades

Jefsen, O. H., Holde, K., McGrath, J. J., Rajagopal, V. M., Albiñana, C., Vilhjálmsson, B. J., Grove, J., Agerbo, E., Yilmaz, Z., Plana-Ripoll, O., Munk-Olsen, T., Demontis, D., Børglum, A., Mors, O., Bulik, C. M., Mortensen, P. B. & Petersen, L. V., 1 Aug 2024, In: Biological Psychiatry. 96, 3, p. 222-229 8 p.

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5 Citations (Scopus)

20 Downloads (Pure)

Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome-wide association studies

Qi, B., Graff, M., Bulik, C. M., North, K. E., Munn-Chernoff, M. A. & Grove, J. (Member of author collaboration), Feb 2024, In: Brain and Behavior. 14, 2, p. e3294 e3294.

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Open Access

3 Citations (Scopus)

Shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD

Nielsen, T. T., Duan, J., Levey, D. F., Walters, G. B., Johnson, E. C., Thorgeirsson, T., Werge, T., Mortensen, P. B., Stefansson, H., Stefansson, K., Hougaard, D. M., Agrawal, A., Gelernter, J., Grove, J., Børglum, A. & Demontis, D., Sept 2024, In: Nature Mental Health. 2, 9, p. 1071-1083 13 p., 108535.

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1 Citation (Scopus)

The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder

Petersen, L., Christiansen, G., Chatwin, H., Yilmaz, Z., Schendel, D., Bulik, C., Grove, J., Brikell, I., Semark, B., Holde, K., Abdulkadir, M., Hubel, C., Albiñana, C., Vilhjálmsson, B., Borglum, A., Demontis, D. & Mortensen, P., 17 Jul 2024, (Research square).

Research output: Working paper/Preprint › Preprint

Unraveling the metabolomic architecture of autism in a large Danish population-based cohort

Ottosson, F., Russo, F., Abrahamsson, A., MacSween, N., Courraud, J., Skogstrand, K., Melander, O., Ericson, U., Orho-Melander, M., Cohen, A. S., Grove, J., Mortensen, P. B., Hougaard, D. M. & Ernst, M., Dec 2024, In: BMC Medicine. 22, 1, 302.

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Open Access

1 Citation (Scopus)

Whole genome sequencing analysis identifies sex differences of familial pattern contributing to phenotypic diversity in autism

Kim, S. W., Lee, H., Song, D. Y., Lee, G. H., Ji, J., Park, J. W., Han, J. H., Lee, J. W., Byun, H. J., Son, J. H., Kim, Y. R., Lee, Y., Kim, J., Jung, A., Lee, J., Kim, E., Kim, S. H., Lee, J. H., Satterstrom, F. K. & Girirajan, S. & 6 others, Børglum, A. D., Grove, J., Kim, E., Werling, D. M., Yoo, H. J. & An, J. Y., 27 Sept 2024, In: Genome Medicine. 16, 1, p. 114 1 p., 114.

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6 Citations (Scopus)

2023

Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

ADHD Working Group of the Psychiatric Genomics Consortium, Apr 2023, In: Nature Genetics. 55, 4, p. 730 1 p.

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5 Citations (Scopus)

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G. & Thorgeirsson, T. & 23 others, Stefánsson, H., Musliner, K. L., Rajagopal, V. M., Farajzadeh, L., Thirstrup, J., Vilhjálmsson, B. J., McGrath, J. J., Mattheisen, M., Meier, S., Agerbo, E., Stefánsson, K., Nordentoft, M., Werge, T., Hougaard, D. M., Mortensen, P. B., Stein, M. B., Gelernter, J., Hovatta, I., Roussos, P., Daly, M. J., Mors, O., Palotie, A. & Børglum, A. D., Jul 2023, In: Nature Medicine. 29, 7, p. 1832-1844 13 p.

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129 Citations (Scopus)

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H. & Baldursson, G. & 28 others, Davidsdottir, K., Haraldsdottir, G. S., Agerbo, E., Hoffman, G. E., Dalsgaard, S., Martin, J., Ribasés, M., Boomsma, D. I., Soler Artigas, M., Roth Mota, N., Howrigan, D., Medland, S. E., Zayats, T., Rajagopal, V. M., Nordentoft, M., Mors, O., Hougaard, D. M., Mortensen, P. B., Daly, M. J., Faraone, S. V., Stefansson, H., Roussos, P., Franke, B., Werge, T., Neale, B. M., Stefansson, K., Børglum, A. D. & ADHD Working Group of the Psychiatric Genomics Consortium, Feb 2023, In: Nature Genetics. 55, 2, p. 198-208 11 p.

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301 Citations (Scopus)

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C. & Bilbao, J. R. & 69 others, Allard, C., Groleau, M., Kuulasmaa, T., Leirer, D. J., White, F., Jacques, P. É., Cheng, H., Hao, K., Andreassen, O. A., Åsvold, B. O., Atalay, M., Bhatta, L., Bouchard, L., Brumpton, B. M., Brunak, S., Bybjerg-Grauholm, J., Ebbing, C., Elliott, P., Engelbrechtsen, L., Erikstrup, C., Estarlich, M., Franks, S., Gaillard, R., Geller, F., Grove, J., Hougaard, D., Kajantie, E., Morgen, C. S., Nohr, E. A., Nyegaard, M., Palmer, C. N. A., Pedersen, O. B., The Early Growth Genetics (EGG) Consortium, Rivadeneira, F., Sebert, S. P., Shields, B., Stoltenberg, C., Surakka, I., Thørner, L. W., Ullum, H., Vaarasmaki, M., Vilhjalmsson, B. J., Willer, C. J., Lakka, T. A., Gybel-Brask, D., Bustamante, M., Hansen, T., Pearson, E. R., Reynolds, R., Ostrowski, S. R., Pennell, C. E., Jaddoe, V. W. V., F. Felix, J., Hattersley, A. T., Melbye, M., Lawlor, D. A., Hveem, K., Werge, T., Nielsen, H. S., Magnus, P., Evans, D., Jacobsson, B., Järvelin, M.-R., Zhang, G., Hivert, M.-F., Johansson, S. E., Freathy, R. M., Feenstra, B. & Njølstad, P. R., Nov 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.

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20 Citations (Scopus)

24 Downloads (Pure)

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity

Rajagopal, V. M., Ganna, A., Coleman, J. R. I., Allegrini, A., Voloudakis, G., Grove, J., Als, T. D., Horsdal, H. T., Petersen, L., Appadurai, V., Schork, A., Buil, A., Bulik, C. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, M., Werge, T. & iPSYCH-Broad Consortium & 7 others, Mortensen, P. B., Breen, G., Roussos, P., Plomin, R., Agerbo, E., Børglum, A. D. & Demontis, D., Jan 2023, In: Scientific Reports. 13, 429.

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13 Citations (Scopus)

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores

Albiñana, C., Zhu, Z., Schork, A. J., Ingason, A., Aschard, H., Brikell, I., Bulik, C. M., Petersen, L. V., Agerbo, E., Grove, J., Nordentoft, M., Hougaard, D. M., Werge, T., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Neale, B. M., Privé, F. & Vilhjálmsson, B. J., Aug 2023, In: Nature Communications. 14, 1, 4702.

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22 Citations (Scopus)

9 Downloads (Pure)

Phenotypic effects of genetic variants associated with autism

Rolland, T., Cliquet, F., Anney, R. J. L., Moreau, C., Traut, N., Mathieu, A., Huguet, G., Duan, J., Warrier, V., Portalier, S., Dry, L., Leblond, C. S., Douard, E., Amsellem, F., Malesys, S., Maruani, A., Toro, R., Børglum, A. D., Grove, J. & Baron-Cohen, S. & 5 others, Packer, A., Chung, W. K., Jacquemont, S., Delorme, R. & Bourgeron, T., Jul 2023, In: Nature Medicine. 29, 7, p. 1671-1680 10 p.

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36 Citations (Scopus)

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Polygenic liability, stressful life events and risk for secondary-treated depression in early life: a nationwide register-based case-cohort study

Musliner, K. L., Andersen, K. K., Agerbo, E., Albiñana, C., Vilhjalmsson, B. J., Rajagopal, V. M., Bybjerg-Grauholm, J., Bækved-Hansen, M., Pedersen, C. B., Pedersen, M. G., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M. & Mortensen, P. B. & 2 others, Suppli, N. P. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2023, In: Psychological Medicine. 53, 1, p. 217-226 10 p.

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8 Citations (Scopus)

Polygenic risk prediction: why and when out-of-sample prediction R² can exceed SNP-based heritability

Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 2023, In: American Journal of Human Genetics. 110, 7, p. 1207-1215 9 p.

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8 Citations (Scopus)

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

Borbye-Lorenzen, N., Zhu, Z., Agerbo, E., Albiñana, C., Benros, M. E., Bian, B., Børglum, A. D., Bulik, C. M., Debost, J.-C. P. G., Grove, J., Hougaard, D. M., McRae, A. F., Mors, O., Mortensen, P. B., Musliner, K. L., Nordentoft, M., Petersen, L. V., Privé, F., Sidorenko, J. & Skogstrand, K. & 4 others, Werge, T., Wray, N. R., Vilhjálmsson, B. J. & McGrath, J. J., 13 Dec 2023, In: Cell Genomics. 3, 12, p. 100457 100457.

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4 Citations (Scopus)

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2022

Accounting for age of onset and family history improves power in genome-wide association studies

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J. & Privé, F. & 1 others, Vilhjálmsson, B. J., 3 Mar 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.

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17 Citations (Scopus)

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A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

Antaki, D., Guevara, J., Maihofer, A. X., Klein, M., Gujral, M., Grove, J., Carey, C. E., Hong, O., Arranz, M. J., Hervas, A., Corsello, C., Vaux, K. K., Muotri, A. R., Iakoucheva, L. M., Courchesne, E., Pierce, K., Gleeson, J. G., Robinson, E. B., Nievergelt, C. M. & Sebat, J., Sept 2022, In: Nature Genetics. 54, 9, p. 1284-1292 9 p.

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108 Citations (Scopus)

A saturated map of common genetic variants associated with human height

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S.-H., Ferreira, T., Highland, H. H. & Ji, Y. & 37 others, Karaderi, T., Lin, K., Lüll, K., Malden, D. E., Medina-Gomez, C., Machado, M., Moore, A., Rüeger, S., Sim, X., Vrieze, S., Ahluwalia, T. S., Akiyama, M., Andersen, M. K., Grove, J., Hansen, T. F., Jørgensen, T., Mattheisen, M., Petersen, L. V., Wang, Z., Børglum, A. D., Dantoft, T. M., Grarup, N., Hansen, T., Huang, W., Nielsen, C. S., Pedersen, O., Ng, M. C. Y., Sun, Y. V., Winkler, T. W., Yang, J., 23andMe Research Team, VA Million Vet Program, DiscovEHR Collaboration, eMERGE Consortium, Lifelines Cohort Study, The PRACTICAL Consortium & Understanding Society Scientific Group, 27 Oct 2022, In: Nature. 610, 7933, p. 704–712 9 p.

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354 Citations (Scopus)

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Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B. & Ribasés, M. & 2 others, Børglum, A. D. & Demontis, D., Aug 2022, In: Nature Genetics. 54, 8, p. 1117-1124 8 p.

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37 Citations (Scopus)

Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism

Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Børglum, A. D., Werge, T., Nordentoft, M., Mortensen, P. B. & Agerbo, E., Jan 2022, In: Autism Research. 15, 1, p. 171-182 12 p.

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9 Citations (Scopus)

Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis

Grotzinger, A. D., Mallard, T. T., Akingbuwa, W. A., Ip, H. F., Adams, M. J., Lewis, C. M., McIntosh, A. M., Grove, J., Dalsgaard, S., Lesch, K. P., Strom, N., Meier, S. M., Mattheisen, M., Børglum, A. D., Mors, O., Breen, G., iPSYCH, Tourette Syndrome and Obsessive Compulsive Disorder Working Group of the Psychiatric Genetics Consortium, Bipolar Disorder Working Group of the Psychiatric Genetics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genetics Consortium & 6 others, Schizophrenia Working Group of the Psychiatric Genetics Consortium, Lee, P. H., Kendler, K. S., Smoller, J. W., Tucker-Drob, E. M. & Nivard, M. G., May 2022, In: Nature Genetics. 54, 5, p. 548-559 12 p.

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147 Citations (Scopus)

Genetic correlates of phenotypic heterogeneity in autism

Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Rowitch, D. H., Hurles, M. E., Geschwind, D. H., Børglum, A. D., Robinson, E. B., Grove, J., Martin, H. C., Bourgeron, T., Baron-Cohen, S., EU-AIMS LEAP & iPSYCH-Autism Working Group & 1 others, Spectrum 10K and APEX Consortia, Sept 2022, In: Nature Genetics. 54, 9, p. 1293-1304 12 p.

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74 Citations (Scopus)

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Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D. & Nielsen, K. R. & 19 others, Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, H., Pers, T. H., Mortensen, P. B., Mors, O., Nordentoft, M., Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, A., Melbye, M., Ullum, H., Berkovic, S. F., Werge, T. & Feenstra, B., 1 Feb 2022, In: Brain : a journal of neurology. 145, 2, p. 555–568 14 p.

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37 Citations (Scopus)

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Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample

Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M. & Mors, O. & 3 others, Nordentoft, M., Mortensen, P. B. & Musliner, K. L., Oct 2022, In: Biological Psychiatry: Global Open Science. 2, 4, p. 400-410 11 p.

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7 Citations (Scopus)

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

Mattheisen, M., Grove, J., Als, T. D., Martin, J., Voloudakis, G., Meier, S., Demontis, D., Bendl, J., Walters, R., Carey, C. E., Rosengren, A., Strom, N. I., Hauberg, M. E., Zeng, B., Hoffman, G., Zhang, W., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Agerbo, E. & Cormand, B. & 14 others, Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Buxbaum, J. D., Faraone, S. V., Franke, B., Dalsgaard, S., Mortensen, P. B., Robinson, E. B., Roussos, P., Neale, B. M., Daly, M. J. & Børglum, A. D., Oct 2022, In: Nature Genetics. 54, 10, p. 1470-1478 9 p.

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42 Citations (Scopus)

Identifying the Common Genetic Basis of Antidepressant Response

GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2022, In: Biological Psychiatry: Global Open Science. 2, 2, p. 115-126 12 p.

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74 Citations (Scopus)

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J. C., Koopmans, F., Magnusson, S., Richards, A. L., Sidorenko, J. & Wu, Y. & 31 others, Zeng, J., Grove, J., Kim, M., Li, Z., Voloudakis, G., Zhang, W., Adams, M., Agartz, I., Atkinson, E. G., Agerbo, E., Al Eissa, M., Albus, M., Alexander, M., Alizadeh, B. Z., Alptekin, K., Als, T. D., Amin, F., Arolt, V., Arrojo, M., Athanasiu, L., Azevedo, M. H., Demontis, D., Mattheisen, M., McGrath, J. J., Meier, S., Chen, W. J., Mors, O., Mortensen, P. B., Børglum, A. D., Yang, J. & Indonesia Schizophrenia Consortium, 21 Apr 2022, In: Nature. 604, 7906, p. 502-508 7 p.

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1358 Citations (Scopus)

Maternal health around pregnancy and autism risk: a diagnosis-wide, population-based study

Kodesh, A., Levine, S. Z., Khachadourian, V., Rahman, R., Schlessinger, A., O'Reilly, P. F., Grove, J., Schendel, D., Buxbaum, J. D., Croen, L., Reichenberg, A., Sandin, S. & Janecka, M., Dec 2022, In: Psychological Medicine. 52, 16, p. 4076-4084 9 p.

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13 Citations (Scopus)

Parental inflammatory bowel disease and autism in children

Sadik, A., Dardani, C., Pagoni, P., Havdahl, A., Stergiakouli, E., Khandaker, G. M., Sullivan, S. A., Zammit, S., Jones, H. J., Davey Smith, G., Dalman, C., Karlsson, H., Gardner, R. M., Rai, D. & The iPSYCH Autism Spectrum Disorder Working Group, Jul 2022, In: Nature Medicine. 28, 7, p. 1406-1411 6 p.

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Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

Antaki, D., Guevara, J., Maihofer, A. X., Klein, M., Gujral, M., Grove, J., Carey, C. E., Hong, O., Arranz, M. J., Hervas, A., Corsello, C., Vaux, K. K., Muotri, A. R., Iakoucheva, L. M., Courchesne, E., Pierce, K., Gleeson, J. G., Robinson, E. B., Nievergelt, C. M. & Sebat, J., Aug 2022, In: Nature Genetics. 54, 8, 1 p., 1259.

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2 Citations (Scopus)

Rare coding variants in ten genes confer substantial risk for schizophrenia

Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M. & DeLisi, L. & 91 others, Dodge, S., Escamilla, M. A., Eskelinen, S., Fanous, A. H., Faraone, S. V., Fiorentino, A., Francioli, L., Gabriel, S. B., Gage, D., Gagliano Taliun, S. A., Ganna, A., Genovese, G., Glahn, D. C., Grove, J., Hall, M. H., Hämäläinen, E., Heyne, H. O., Holi, M., Hougaard, D. M., Howrigan, D. P., Huang, H., Hwu, H. G., Kahn, R. S., Kang, H. M., Karczewski, K. J., Kirov, G., Knowles, J. A., Lee, F. S., Lehrer, D. S., Lescai, F., Malaspina, D., Marder, S. R., McCarroll, S. A., McIntosh, A. M., Medeiros, H., Milani, L., Morley, C. P., Morris, D. W., Mortensen, P. B., Myers, R. M., Nordentoft, M., O’Brien, N. L., Olivares, A. M., Ongur, D., Ouwehand, W. H., Palmer, D. S., Paunio, T., Quested, D., Rapaport, M. H., Rees, E., Rollins, B., Satterstrom, F. K., Schatzberg, A., Scolnick, E., Scott, L. J., Sharp, S. I., Sklar, P., Smoller, J. W., Sobell, J. L., Solomonson, M., Stahl, E. A., Stevens, C. R., Suvisaari, J., Tiao, G., Watson, S. J., Watts, N. A., Blackwood, D. H., Børglum, A. D., Cohen, B. M., Corvin, A. P., Esko, T., Freimer, N. B., Glatt, S. J., Hultman, C. M., McQuillin, A., Palotie, A., Pato, C. N., Pato, M. T., Pulver, A. E., St. Clair, D., Tsuang, M. T., Vawter, M. P., Walters, J. T., Werge, T. M., Ophoff, R. A., Sullivan, P. F., Owen, M. J., Boehnke, M., O’Donovan, M. C., Neale, B. M. & Daly, M. J., Apr 2022, In: Nature. 604, 7906, p. 509-516 8 p.

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454 Citations (Scopus)

Seasonal Variation and Risk of Febrile Seizures: A Danish Nationwide Cohort Study

Christensen, K. J., Dreier, J. W., Skotte, L., Feenstra, B., Grove, J., Børglum, A. D., Mitrovic, M., Cotsapas, C. & Christensen, J., Apr 2022, In: Neuroepidemiology. 56, 2, p. 138-145 8 p.

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6 Citations (Scopus)

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH, Jan 2022, In: Biological Psychiatry. 91, 1, p. 102-117 16 p.

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70 Citations (Scopus)

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p

Weiner, D. J., Ling, E., Erdin, S., Tai, D. J. C., Yadav, R., Grove, J., Fu, J. M., Nadig, A., Carey, C. E., Baya, N., Bybjerg-Grauholm, J., iPSYCH Consortium, ASD Working Group of the Psychiatric Genomics Consortium, ADHD Working Group of the Psychiatric Genomics Consortium, Berretta, S., Macosko, E. Z., Sebat, J., O'Connor, L. J., Hougaard, D. M. & Børglum, A. D. & 3 others, Talkowski, M. E., McCarroll, S. A. & Robinson, E. B., Nov 2022, In: Nature Genetics. 54, 11, p. 1630-1639 10 p.

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20 Citations (Scopus)

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Jakob Grove

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