Research

Core programmes of the Retroviral Molecular Biology Group:

Retroviruses comprise a large group of animal viruses. These viruses have attracted attention because of a) their unique replication cycle that involves copying of genetic information from RNA to DNA by reverse transcription and insertion of viral DNA into the genome of the host cell, b) the pathogenicity of some of viruses in man and animals, c) the extensive occurrence of retroviral sequences in the normal genome of man and animals, and d) the exploitation of retrovirus-based gene-transfer vehicles as tools in research and in gene-therapy trials. Our work uses mainly viruses and vectors of the murine leukemia virus group including related viral isolates from other species.

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