Research output per year
Research output per year
Personal profile
Profile
I am interested in understanding the neurobiological mechanisms of depression and underlying rapid acting antidepressants, with special attention on the role of neuroplasticity and stress-induced neuroplasticity-related mechanisms. I am particularly interested in neuroplasticity at different levels in prefrontal cortex and hippocampus: structural plasticity, functional synaptic plasticity, and the molecular and cellular mechanisms accompanying such changes.
Job responsibilities
I work in animal studies (dissection of regions of interest, injections, and various behavioral tests), histology, molecular biology, animal surgery, primary neuronal cultures, immunohistochemistry and immunofluorescence staining, imaging techniques with different types of microscopies, and morphological image analysis in the brain.
Education/Academic qualification
Medicine, PhD, Neuronal and synaptic plasticity in subregions of rat hippocampus after antidepressant treatment, Aarhus University
1 May 2005 → 31 Dec 2008
Award Date: 18 Mar 2009
Molecular biology, Master of Science, MSc, Aarhus University
Award Date: 15 Oct 2004
Medicine, Bachelor, Central South University
1 Sept 1987 → 1 Jul 1992
Award Date: 1 Jul 1992
Areas of expertise
- Pathomechanism of depression
- Neuroplasticity in hippocampus
- Mechanisms of antidepressant
- Stress-related mechanisms
- Brain morphological analysis
Fingerprint
Dive into the research topics where Fenghua Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
-
Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and neuroinflammation
Kjærgaard, K., Mikkelsen, A. C. D., Landau, A., Eriksen, P. L., Hamilton-Dutoit, S. J., Magnusson, N. E., Thomsen, M., Chen, F., Vilstrup, H. V. A., Mookerjee, R. P., Bay-Richter, C. & Thomsen, K. L., Mar 2024, In: JHEP Reports. 6, 3, 100992.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access10 Citations (Scopus) -
Cognitive dysfunction is associated with systemic inflammation and neuroinflammation in a rodent model of NASH
Mikkelsen, A. C. D., Kjærgaard, K., Bay-Richter, C., Landau, A., Eriksen, P. L., Jalan, R., Hamilton-Dutoit, S. J., Chen, F., Vilstrup, H. V. A., Magnusson, N. E., Mookerjee, R. P. & Thomsen, K. L., 7 Oct 2021.Research output: Contribution to conference › Conference abstract for conference › Research
-
Cognitive dysfunction is associated with systemic inflammation and neuroinflammation in a rodent model of non-alcoholic steatohepatitis
Mikkelsen, A. C. D., Kjærgaard, K., Bay-Richter, C., Landau, A., Eriksen, P. L., Jalan, R., Hamilton-Dutoit, S. J., Chen, F., Vilstrup, H. V. A., Magnusson, N. E., Mookerjee, R. P. & Thomsen, K. L., 16 Sept 2021.Research output: Contribution to conference › Poster › Research
-
The rat hippocampal gliovascular system following one week vortioxetine and fluoxetine
Chen, F., Danladi, J., Ardalan, M., Nyengaard, J. R., Sánchez, C. & Wegener, G., Jan 2021, In: European Neuropsychopharmacology. 42, p. 45-56 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
4 Citations (Scopus) -
Hippocampal volume and cell number in depression, schizophrenia, and suicide subjects
Chen, F., Bertelsen, A. B., Holm, I. E., Nyengaard, J. R., Rosenberg, R. & Dorph-Petersen, K. A., 2020, In: Brain Research. 1727, 15 p., 146546.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
70 Citations (Scopus)
Activities
- 3 Lecture and oral contribution
-
Hippocampus ved svær unipolar depression: Et postmortelt stereologisk studie af rumfang og celleantal
Chen, F. (Invited speaker)
8 Nov 2012Activity: Presentations, memberships, employment, ownership and other activities › Lecture and oral contribution
-
Hippocampus in depression; a postmortem stereological study of hippocampal volume and cell number
Chen, F. (Invited speaker)
13 Oct 2012 → 18 Oct 2012Activity: Presentations, memberships, employment, ownership and other activities › Lecture and oral contribution
-
Mitochondrial dynamics in the hippocampus is influenced by antidepressant treatment in a genetic rat model of depression
Chen, F. (Lecturer)
3 Jun 2012 → 7 Jun 2012Activity: Presentations, memberships, employment, ownership and other activities › Lecture and oral contribution