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Esben Meldgaard Høgh Quistgaard

Up, down, and around: Identifying recurrent interactions within and between super-secondary structures in β-propellers

Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

The examination and analysis of super-secondary structures or other speci fi c structural patterns associated with particular functions, sequence motifs, or structural contexts require that the set of structures examined shares the same feature. This seems obvious but in practice this may often present problems such as identifying complete sets of data avoiding false positives. In the case of the β -propeller structures the symmetry of the propeller creates problems for many structure similarity search programs. Here we present a procedure that will identify propeller structures in PDB and assign them to the different N-propeller types. In addition we outline methods to examine similarities and differences within and between the four stranded up-and-down blades of the β-propeller.

Original languageEnglish
Title of host publicationProtein Supersecondary Structures
Number of pages16
PublisherThe Humana Press Inc.
Publication year1 Jan 2013
Pages35-50
ISBN (print)9781627030649
DOIs
Publication statusPublished - 1 Jan 2013
SeriesMethods in Molecular Biology
Volume932
ISSN1064-3745

    Research areas

  • Beta sheet, Beta-propellers, Classi fication, Structural similarity

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