Erik Ernst

‘Vanishing embryo syndrome’ in IVF/ICSI

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperLetterResearch


  • Institute of Epidemiology and Social Medicine
  • Institute of Biostatistics
  • Obstetrics and Gynaecology
BACKGROUND: In a Danish population-based cohort study assessing the risk of cerebral palsy in children bornafter IVF, we made some interesting observations regarding ‘vanishing co-embryos’. METHODS andRESULTS: All live-born children born in Denmark from 1 January 1995 to 31 December 2000 were included inthis analysis. The children conceived by IVF/ICSI (9444) were identified through the IVF Register, the childrenconceived without IVF/ICSI (395 025) were identified through The Danish Medical Birth Register. Main outcomemeasure was the incidence of cerebral palsy. Within the IVF/ICSI children we found indications of an increasedrisk of cerebral palsy in those children resulting from pregnancies, where the number of embryos transferred washigher than the number of children born. CONCLUSIONS: The association between vanishing embryo syndromeand incidence of cerebral palsy following IVF requires further investigation in larger, adequately powered, studies.
Original languageEnglish
JournalHuman Reproduction
Pages (from-to)2550-2551
Number of pages2
Publication statusPublished - 2005

    Research areas

  • cerebral palsy, IVF, vanishing embryo syndrome

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