Department of Biology

Aarhus University Seal / Aarhus Universitets segl

Erik Baatrup

Sexual characteristics are altered by 4-tert-octylphenol and 17beta-estradiol in the adult male guppy (Poecilia reticulata).

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Sexual characteristics are altered by 4-tert-octylphenol and 17beta-estradiol in the adult male guppy (Poecilia reticulata). / Toft, G; Baatrup, E.

In: Ecotoxicology and Environmental Safety, Vol. 48, No. 1, 2001, p. 76-84.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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@article{4750a450d4a211dcabe4000ea68e967b,
title = "Sexual characteristics are altered by 4-tert-octylphenol and 17beta-estradiol in the adult male guppy (Poecilia reticulata).",
abstract = "Endocrine-disrupting chemicals (EDCs) are believed to interfere with animal reproduction, but only few biomarkers above the cellular level have been developed to assess the adverse effects of these chemicals. Using the guppy (Poecilia reticulata) as a model organism, studies have been undertaken with the object of comparing biomarker responses to EDCs at increasing levels of biological complexity. Short-term exposure to the xenoestrogen 4-tert-octylphenol and the natural estrogen 17beta-estradiol (E2) changed important sexual characteristics in the adult male guppy. Both compounds increased the number of sperm cells in the ejaculates, reduced the area and color intensity of the sexually attractive orange spots, and inhibited testis growth. In the case of E2, the effects on sperm count and coloration were still evident after 3 months of recovery in clean water. Preliminary results on male reproductive capability demonstrated that treated males produced fewer offspring than untreated fish, indicating an impairment of reproduction itself. Udgivelsesdato: 2001-Jan",
keywords = "Animals, Biological Markers, Environmental Exposure, Environmental Monitoring, Estradiol, Infertility, Male, Male, Phenols, Poecilia, Sperm Count, Testis, Water Pollutants, Chemical",
author = "G Toft and E Baatrup",
year = "2001",
doi = "10.1006/eesa.2000.1985",
language = "English",
volume = "48",
pages = "76--84",
journal = "Ecotoxicology and Environmental Safety",
issn = "0147-6513",
publisher = "Academic Press",
number = "1",

}

RIS

TY - JOUR

T1 - Sexual characteristics are altered by 4-tert-octylphenol and 17beta-estradiol in the adult male guppy (Poecilia reticulata).

AU - Toft, G

AU - Baatrup, E

PY - 2001

Y1 - 2001

N2 - Endocrine-disrupting chemicals (EDCs) are believed to interfere with animal reproduction, but only few biomarkers above the cellular level have been developed to assess the adverse effects of these chemicals. Using the guppy (Poecilia reticulata) as a model organism, studies have been undertaken with the object of comparing biomarker responses to EDCs at increasing levels of biological complexity. Short-term exposure to the xenoestrogen 4-tert-octylphenol and the natural estrogen 17beta-estradiol (E2) changed important sexual characteristics in the adult male guppy. Both compounds increased the number of sperm cells in the ejaculates, reduced the area and color intensity of the sexually attractive orange spots, and inhibited testis growth. In the case of E2, the effects on sperm count and coloration were still evident after 3 months of recovery in clean water. Preliminary results on male reproductive capability demonstrated that treated males produced fewer offspring than untreated fish, indicating an impairment of reproduction itself. Udgivelsesdato: 2001-Jan

AB - Endocrine-disrupting chemicals (EDCs) are believed to interfere with animal reproduction, but only few biomarkers above the cellular level have been developed to assess the adverse effects of these chemicals. Using the guppy (Poecilia reticulata) as a model organism, studies have been undertaken with the object of comparing biomarker responses to EDCs at increasing levels of biological complexity. Short-term exposure to the xenoestrogen 4-tert-octylphenol and the natural estrogen 17beta-estradiol (E2) changed important sexual characteristics in the adult male guppy. Both compounds increased the number of sperm cells in the ejaculates, reduced the area and color intensity of the sexually attractive orange spots, and inhibited testis growth. In the case of E2, the effects on sperm count and coloration were still evident after 3 months of recovery in clean water. Preliminary results on male reproductive capability demonstrated that treated males produced fewer offspring than untreated fish, indicating an impairment of reproduction itself. Udgivelsesdato: 2001-Jan

KW - Animals

KW - Biological Markers

KW - Environmental Exposure

KW - Environmental Monitoring

KW - Estradiol

KW - Infertility, Male

KW - Male

KW - Phenols

KW - Poecilia

KW - Sperm Count

KW - Testis

KW - Water Pollutants, Chemical

U2 - 10.1006/eesa.2000.1985

DO - 10.1006/eesa.2000.1985

M3 - Journal article

C2 - 11161681

VL - 48

SP - 76

EP - 84

JO - Ecotoxicology and Environmental Safety

JF - Ecotoxicology and Environmental Safety

SN - 0147-6513

IS - 1

ER -