Research output per year
Research output per year
Research output
- 19 results
Search results
-
2025
Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis
Kristoffersen, E. L., McRae, E. K. S., Sørensen, N. R., Holliger, P. & Andersen, E. S., 6 Jun 2025, In: Nucleic Acids Research. 53, 11Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
2024
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme
McRae, E. K. S., Wan, C. J. K., Kristoffersen, E. L., Hansen, K., Gianni, E., Gallego, I., Curran, J. F., Attwater, J., Holliger, P. & Andersen, E. S., 16 Jan 2024, In: Proceedings of the National Academy of Sciences (PNAS). 121, 3, p. e2313332121 e2313332121.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access12 Citations (Scopus) -
2023
Inhibited complete folding of consecutive human telomeric G-quadruplexes
Kristoffersen, E. L., Coletta, A., Lund, L. M., Schiøtt, B. & Birkedal, V., Feb 2023, In: Nucleic Acids Research. 51, 4, p. 1571-1582 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access3 Citations (Scopus) -
2022
Rolling Circle RNA Synthesis Catalysed by RNA
Kristoffersen, E. L., Burman, M., Noy, A. & Holliger, P., Feb 2022, In: eLife. 11, 25 p., e75186.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access30 Citations (Scopus) -
2020
Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay
Uhd, J., Miotke, L., Ji, H. P., Dunaeva, M., Pruijn, G. J. M., Jørgensen, C. D., Kristoffersen, E. L., Birkedal, V., Yde, C. W., Nielsen, F. C., Hansen, J. & Astakhova, K., Sept 2020, In: Analyst. 145, 17, p. 5836-5844Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
9 Citations (Scopus) -
2019
Stable Off-Path Structures in the Folding Dynamics of Two Consecutive Telomeric DNG G-Quadruplexes
Kristoffersen, E. L. & Birkedal, V., 15 Feb 2019, p. 138A-138A. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study
Tesauro, C., Simonsen, A. K., Andersen, M. B., Petersen, K. W., Kristoffersen, E. L., Algreen, L., Hansen, N. Y., Andersen, A. B., Jakobsen, A. K., Stougaard, M., Gromov, P., Knudsen, B. R. & Gromova, I., 29 Nov 2019, In: BMC Cancer. 19, 1, 1158.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
44 Citations (Scopus) -
2018
Single-Molecule FRET Investigations of Tandem Human Telomeric G-Quadruplex Structures
Kristoffersen, E. L., Aznauryan, M. & Birkedal, V., 2018, In: Biophysical Journal. 114, 3 , p. 597aResearch output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research
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2017
Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study
Andersen, M., Tesauro, C., Gonzalez, M., Kristoffersen, E. L., Alonso, C., Rubiales, G., Coletta, A., Hougaard, R. F., Stougaard, M., Ho, M.Y.-P., Palacios, F. & Knudsen, B. R., 7 Feb 2017, In: Nanoscale. 9, 5, p. 1886-1895 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
11 Citations (Scopus) -
Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events
Kristoffersen, E. L., Jørgensen, A. G., Jørgensen, L. A., Jensen, P. W., W Byl, J. A., Osheroff, N., Andersen, A. H., Stougaard, M., Ho, Y.-P. & Knudsen, B. R., 1 Jul 2017, In: Nucleic Acids Research. 45, 13, p. 7855-7869 15 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)258 Downloads (Pure) -
2016
A Study of Designed DNA Nanostructures and their use in Enzyme Activity Detection
Kristoffersen, E. L., 24 Oct 2016Research output: Types of Thesis › PhD thesis
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Microfluidics-based Single Cell Analytical Platforms for Characterization of Cancer
Kristoffersen, E. L., Jepsen, M. L., Knudsen, B. R. & Ho, Y.-P., 28 May 2016, Nanomedicine. Howard, A. K., Vorup-Jensen, T. & Peer, D. (eds.). New York, NY: Springer, p. 77-95 19 p. (Advances in Delivery Science and Technology).Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review
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Optimized Detection of Plasmodium falciparum Topoisomerase I Enzyme Activity in a Complex Biological Sample by the Use of Molecular Beacons
Jørgensen, A. G., Kristoffersen, E. L., Petersen, K. V., Ho, Y.-P., Stougaard, M. & Knudsen, B. R., 15 Nov 2016, In: Sensors. 16, 11, 16 p., 1916.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access8 Citations (Scopus) -
2015
Molecular Beacon Enables Combination of Highly Processive and Highly Sensitive Rolling Circle Amplification Readouts for Detection of DNA-Modifying Enzymes
Kristoffersen, E. L., Gonzales, M., Stougaard, M. & Tesauro, C., Jun 2015, In: Nano Life. 05, 02, 7 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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Real-time investigation of human topoisomerase I reaction kinetics using an optical sensor: a fast method for drug screening and determination of active enzyme concentrations
Kristoffersen, E. L., Jørgensen, L. A., Franch, O., Etzerodt, M., Frøhlich, R., Bjergbæk, L., Stougaard, M., Ho, Y.-P. & Knudsen, B. R., 21 May 2015, In: Nanoscale. 7, 21, p. 9825-9834 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
12 Citations (Scopus) -
2013
DNA-Based Sensor for Real-Time Measurement of the Enzymatic Activity of Human Topoisomerase I
Marcussen, L. B., Jepsen, M. L., Kristoffersen, E. L., Franch, O., Proszek, J., Ho, Y.-P., Stougaard, M. & Knudsen, B. R., 25 Mar 2013, In: Sensors. 13, 4, p. 4017-4028 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)351 Downloads (Pure) -
Real-time detection of TDP1 activity using a fluorophore-quencher coupled DNA-biosensor
Jensen, P. W., Falconi, M., Kristoffersen, E. L., Simonsen, A. T., Cifuentes, J. B., Marcussen, L., Hougaard, R. F., Vagner, J., Harmsen, C., Jensen, S. J., Ho, Y.-P., Withers, M. A., Lupski, J. R., Koch, J. E., Desideri, A., Knudsen, B. R. & Stougaard, M., 15 Oct 2013, In: Biosensors and Bioelectronics. Volume 48, p. 230–237 8 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
41 Citations (Scopus) -
Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage
Juul, S., Iacovelli, F., Falconi, M., Kragh, S. L., Christensen, B. S., Hougaard, R. F., Franch, O., Kristoffersen, E. L., Stougaard, M., Leong, K. W., Ho, Y.-P., Sørensen, E. S., Birkedal, V., Desideri, A. & Knudsen, B. R., 29 Oct 2013, In: ACS Nano. 7, 11, p. 9724-9734 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
139 Citations (Scopus) -
2012
Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria-Causing Plasmodium Parasites Based on Enzyme Activity Measurement
Juul, S., Nielsen, C. J. F., Labouriau, R., Roy, A., Tesauro, C., Jensen, P. W., Harmsen, C., Kristoffersen, E. L., Chiu, Y.-L., Hougaard, R. F., Fiorani, P., Cox-Singh, J., Tordrup, D. P., Koch, J. E., Bienvenu, A.-L., Desideri, A., Picot, S., Petersen, E., Leong, K. W. & Ho, Y.-P. & 2 others, , Dec 2012, In: A C S Nano. 6, 12, p. 10676-10683 8 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
84 Citations (Scopus)