Elisabeth Bendstrup

Erectile Dysfunction ia a common problem in Interstitial Lung Disease

Research output: Contribution to conferencePosterResearch

  • Andreas Fløe
  • Ole Hilberg, Denmark
  • Marlies Wijsenbeek, Dept. of Respiratory Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands, Denmark
  • Elisabeth Bendstrup
Rationale: The relationship between erectile dysfunction (ED) and chronic diseases, most notably diabetes and atherosclerosis, is well established. Previous studies have shown a relationship between COPD and ED. The pathogenesis is not clearly established, but studies have shown a correlation between chronic hypoxia and ED. We aimed to study the association between interstitial lung disease (ILD) and ED, classified by the International Index of Erectile Function (IIEF). Methods: We included male patients above 18 years of age with a diagnosis of ILD at two European centers. The diagnosis of ILD was based on high-resolution computed tomography (HR-CT) findings and/or a histopathologic pattern supporting ILD in a lung biopsy. Enrolled patients were asked to fulfil the IIEF questionnaire (Danish or Dutch version). From patient files, we obtained information and data on type of ILD, lung function tests, 6 minute walking test (6MWT), arterial puncture or pulse oximetry, co-morbid diseases and prescribed medication. Results: Of 89 patients enrolled, 51 (57.3%) returned the questionnaire. 50 patients were caucasians, one was Asian. Median age was 67 years (range 45-83 years). 10 patients (19.6%) had co-morbid heart disease and/or manifest atherosclerosis, and 6 (11.8%) had diabetes mellitus (DM). 39 (76.5%) had fibrosing ILD on high-resolution CT-scan or lung biopsy (IPF n=24, Fibrosing NSIP n=7, unclassifiable ILD with fibrosis n=8). 35 ILD patients (70%) had ED, and 22 (44%) hereof had severe ED. Having a co-morbidity was not associated with increased risk of ED (OR 0,94, P=0,74). Conclusion: Our data clearly demonstrate that ED is a common problem in ILD. Almost half of all patients in this study had severe ED. This is, to our knowledge, the first study to report on the occurrence of sexual problems among male patients with ILD. The rate of ED was comparable to that found among COPD patients in prior studies. Further research is needed in order to identify specific risk factors for ED among ILD patients.
Original languageEnglish
Publication year16 May 2015
Number of pages1
Publication statusPublished - 16 May 2015
EventAmerican Thoracic Society 2015 International Conference - The Colorado Convention Centre, Denver, CO, United States
Duration: 15 May 201520 May 2015
Conference number: 101


ConferenceAmerican Thoracic Society 2015 International Conference
LocationThe Colorado Convention Centre
CountryUnited States
CityDenver, CO

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