Department of Biological and Chemical Engineering

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Edzard Spillner

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  1. 2023
  2. E-pub ahead of print

    Extract-shaped immune repertoires as source for nanobody-based human IgE in grass pollen allergy. / Aagaard, Josephine Baunvig; Fischer, Michaela ; Lober, Julia et al.

    In: Molecular Biotechnology, 25.01.2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. 2022
  4. Published

    Construction, expression and functional characterization of an engineered antibody against tumor antigen MUC-1C. / Pourjafar, Mona; Miehe, Michaela; Najafi, Rezvan et al.

    In: Protein Expression and Purification, Vol. 199, 106148, 11.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  5. Published

    Nanobody-based human antibody formats act as IgE surrogate in hymenoptera venom allergy. / Aagaard, Josephine Baunvig; Sivelle, Coline; Fischer, Michaela et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 77, No. 9, 09.2022, p. 2859-2862.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Letter › peer-review

  6. Published

    Current research and unmet needs in allergy and immunology in Germany : report presented by the DGfI and DGAKI task force Allergy & Immunology. / Albrecht, Melanie; Schaub, Bianca; Gilles, Stefanie et al.

    In: European Journal of Immunology, Vol. 52, No. 6, 06.2022, p. 851-855.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  7. E-pub ahead of print

    Structural and functional analyses of antibodies specific for modified core N-glycans suggest a role in TH2 responses. / Plum, Melanie; Tjerrild, Luna; Raiber, Tim et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, 2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  8. 2021
  9. E-pub ahead of print

    Carbohydrate Epitopes Currently Recognized as Targets for IgE Antibodies. / Platts-Mills, Thomas; Hilger, Christiane; Jappe, Uta et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, 02.03.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. 2020
  11. Published

    Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy. / Jensen, Rasmus K; Jabs, Frederic; Miehe, Michaela et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 75, No. 8, 08.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  12. Published

    In Silico Evaluation of the Binding Site of Fucosyltransferase 8 and First Attempts to Synthesize an Inhibitor with Drug-Like Properties. / Strecker, Claas; Bärenfänger, Melissa; Miehe, Michaela et al.

    In: ChemBioChem, Vol. 21, No. 13, 07.2020, p. 1923-1931.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  13. Published

    The honey bee venom allergen Api m 10 displays one major IgE epitope, Api m 10160-174. / Rauber, Michèle; Roßbach, Antonia; Jung, Andreas et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 75, No. 7, 07.2020, p. 1756-1759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  14. Published

    The Honeybee Venom Major Allergen Api m 10 (Icarapin) and Its Role in Diagnostics and Treatment of Hymenoptera Venom Allergy. / Jakob, Thilo; Rauber, Michèle Myriam; Perez-Riverol, Amilcar et al.

    In: Current Allergy and Asthma Reports, Vol. 20, No. 9, 48, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  15. 2019
  16. Published

    Work-related allergic asthma : Clinical work-up of a 45-year old male working in animal feed producing industry. / Schmid, J. M.; Skjold, T.; Kolstad, H. A. et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 74, 08.2019, p. 316-316.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review

  17. Published

    Inhibiting phosphatase SHIP-1 enhances suboptimal IgE-mediated activation of human blood basophils but inhibits IgE-mediated activation of cultured human mast cells. / Rasmussen, Pernille; Spillner, Edzard; Hoffmann, Hans Jürgen.

    In: Immunology Letters, Vol. 210, 01.06.2019, p. 40-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  18. 2018
  19. Published

    Characterization of the honeybee venom proteins C1q-like protein and PVF1 and their allergenic potential. / Russkamp, Dennis; Van Vaerenbergh, Matthias; Etzold, Stefanie et al.

    In: Toxicon, Vol. 150, 01.08.2018, p. 198-206.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20. Published

    Venoms of Neotropical wasps lack cross-reactive carbohydrate determinants enabling reliable protein-based specific IgE determination. / Riverol, Amilcar Perez; Miehe, Michaela; Jabs, Frederic et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 141, No. 5, 05.2018, p. 1917-1919.e1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. Published

    Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. / Jabs, Frederic; Plum, Melanie; Laursen, Nick Stub et al.

    In: Nature Communications, Vol. 9, No. 1, 7, 02.01.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  22. Published

    AllergoOncology: Generating a canine anti-cancer IgE against the epidermal growth factor receptor. / Fazekas-Singer, Judit; Singer, Josef; Ilieva, Kristina M et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 142, No. 3, 2018, p. 973-976.e11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  23. Published

    Phospholipase A1-based cross-reactivity among venoms of clinically relevant Hymenoptera from Neotropical and temperate regions. / Perez Riverol, Amilcar; Romani Fernandes, Luís G ; Musacchio Lasa, Alexis et al.

    In: Molecular Immunology, Vol. 93, 2018, p. 87-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  24. 2017
  25. Published

    N-glycan maturation mutants in Lotus japonicus for basic and applied glycoprotein research. / Pedersen, Carina T.; Loke, Ian; Lorentzen, Andrea et al.

    In: Plant Journal, Vol. 91, No. 3, 01.08.2017, p. 394-407.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  26. Published

    Comparing sensitivity of Hymenoptera allergen components on different diagnostic assay systems : Comparing apples and oranges. / Jakob, Thilo; Spillner, Edzard.

    In: Journal of Allergy and Clinical Immunology, Vol. 139, No. 3, 03.2017, p. 1066-1067.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  27. Published

    Application of recombinant antigen 5 allergens from seven allergy-relevant Hymenoptera species in diagnostics. / Schiener, Maximilian; Eberlein, Bernadette; Moreno Aguilar, Carmen et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 72, No. 1, 01.2017, p. 98-108.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  28. Published

    AllergoOncology - the Impact of Allergy in Oncology. EAACI Position Paper. / Jensen-Jarolim, Erika; Bax, HJ; Bianchini, R et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 72, No. 6, 2017, p. 866-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  29. Published

    Benefits and limitations of recombinant allergens in diagnostics of insect venom allergy. / Jakob, Thilo; Blank, Simon; Spillner, Edzard.

    Molecular Allergy Diagnostics. ed. / J. Kleine-Tebbe; T. Jakob. Springer, 2017. p. 341-362.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  30. Published

    Component resolved diagnostics for Hymenoptera venom allergy. / Jakob, Thilo; Müller, Ulrich; Helbling, Arthur et al.

    In: Current Opinion in Allergy and Clinical Immunology, Vol. 17, No. 5, 2017, p. 363-372.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  31. Published

    Diagnostics in hymenoptera venom allergy: Current concepts and developments with special focus on molecular allergy diagnostics. / Jakob, Thilo; Rafei-Shamsabadi, David; Spillner, Edzard et al.

    In: Allergo Journal International, Vol. 26, No. 3, 2017, p. 93-105.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  32. 2016
  33. Published

    Human IgE is efficiently produced in glycosylated and biologically active form in lepidopteran cells. / Bantleon, Frank; Wolf, Sara; Seismann, Henning et al.

    In: Molecular Immunology, Vol. 72, 2016, p. 49-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  34. Published

    Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains. / Offermann, Nadine; Plum, Melanie; Hübner, Uschi et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 71, No. 12, 2016, p. 1794-1799.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  35. Published

    IgE als Zielstruktur für therapeutische Intervention. / Jakob, Thilo; Spillner, Edzard; Lamers, Marinus.

    Allergologie. ed. / Tilo Biedermann; Harald Renz; Werner Heppt; Martin Röcken. Springer, 2016. p. 631-640.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  36. Published

    Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. / Frick, Marcel; Fischer, Jörg; Helbing, Arthur et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 138, No. 6, 2016, p. 1663-1671e9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  37. Published

    Recombinant allergens as a major step in molecular allergology: Scientific and methodological considerations. / Spillner, Edzard.

    Slovenian Pneumology and Allergology Congress joined with Golnik Symposium and Balkan Pneumology Meeting: Personalised Medicine in Respiratory and Immunologic Diseases - Book of Abstacts. ed. / Mitja Kosnik; Robert Marcun. Golnik : University Clinic of Respiratory and Allergic Diseases, Golnik, 2016. p. 77-81.

    Research output: Contribution to book/anthology/report/proceeding › Article in proceedings › Research › peer-review

  38. 2015
  39. Published

    Structure of the omalizumab Fab. / Jensen, Rasmus K; Plum, Melanie; Tjerrild, Luna et al.

    In: Acta Crystallographica Section F: Structural Biology Communications, Vol. 71, No. Pt 4, 04.2015, p. 419-426.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  40. Published

    Decline of Ves v 5-specific blocking capacity in wasp venom-allergic patients after stopping allergen immunotherapy. / Möbs, Christian; Müller, Jan; Rudzio, Annika et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 6, 07.03.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  41. Published

    Diagnostik der Insektengiftallergie: vom Extrakt zum Molekül. / Spillner, Edzard.

    In: Spitzenforschung in der Allergologie, Vol. 2015, 2015, p. 92-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  42. Published

    IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology. / Van Vaerenbergh, Matthias; de Smet, Lina; Rafei-Shamsabadi, David et al.

    In: Molecular Immunology, Vol. 63, No. 2, 2015, p. 449-455.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  43. Published

    Optimierte Diagnostik der Insektengiftallergie durch rekombinante Allergene. / Jakob, Thilo; Blank, Simon; Spillner, Edzard.

    Molekulare Allergiediagnostik. ed. / Jörg Kleine-Tebbe; Thilo Jakob. Springer, 2015. p. 257-275.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  44. Published

    rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom. / Frick, Marcel; Müller, Sabine; Bantleon, Frank et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 70, No. 12, 2015, p. 1665-1668.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  45. 2014
  46. Published

    Aktueller Stand und neue Entwicklungen in der Diagnostik mit rekombinanten Insektengiftallergenen. / Jakob, Thilo; Müller, Sabine; Rafei-Shamsabadi, David et al.

    In: Allergologie, Vol. 37, No. 9, 09.2014, p. 352-361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  47. Published

    Recombinant allergens rarely allow identification of Hymenoptera venom-allergic patients with negative specific IgE to whole venom preparations. / Rafei-Shamsabadi, David; Müller, Sabine; Pfützner, Wolfgang et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 134, No. 2, 08.2014, p. 493-494.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  48. Published

    Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients. / Singer, Josef; Fazekas, Judith; Wang, Wei et al.

    In: Molecular Cancer Therapeutics, Vol. 13, No. 7, 07.2014, p. 1777-1790.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  49. Published

    Selective local inhibition of TNFR1-mediated functions at the site of antigen/allergen presentation. / Bredehorst, Reinhard (Inventor); Grunwald, Thomas (Inventor); Ollert, M.W. (Inventor) et al.

    Jun 25, 2014.

    Research output: Patent

  50. Published

    Component resolution reveals additional major allergens in patients with honeybee venom allergy. / Köhler, Julian; Blank, Simon ; Müller, Sabine et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 133, No. 5, 05.2014, p. 1383-1389.e6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  51. Published

    Basophil activation test using recombinant allergens: highly specific diagnostic method complementing routine tests in wasp venom allergy. / Balzer, Lukas; Pennino, Davide; Blank, Simon et al.

    In: P L o S One, Vol. 9, No. 10, 2014, p. e108619.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  52. Published

    Hymenoptera allergens: from venom to ”venome”. / Spillner, Edzard; Blank, Simon; Jakob, Thilo.

    In: Frontiers in Immunology, Vol. 5, No. 77, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  53. Published

    Identification of hymenoptera venom-allergic patients with negative specific IgE to venom extract by using recombinant allergens. / Cifuentes, Liliana ; Vosseler, Sebastian ; Blank, Simon et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 133, No. 3, 2014, p. 909-910.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  54. 2013
  55. Published

    Donor assists acceptor binding and catalysis of human α1,6-fucosyltransferase. / Kötzler, Miriam P; Blank, Simon; Bantleon, Frank I et al.

    In: A C S Chemical Biology, Vol. 8, No. 8, 16.08.2013, p. 1830-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  56. Published

    Vitellogenins Are New High Molecular Weight Components and Allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris Venom. / Blank, S.; Seismann, H.; McIntyre, M. et al.

    In: P L o S One, Vol. 8, No. 4, 23.04.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  57. Published

    Polistes species venom is devoid of carbohydrate-based cross-reactivity and allows interference-free diagnostics. / Blank, Simon; Neu, Charles; Hasche, Daniel et al.

    In: The Journal of allergy and clinical immunology, Vol. 131, No. 4, 04.2013, p. 1239-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  58. Published

    Controlled activation of complement components for use as endogenous adjuvant. / Bredehorst, Reinhard (Inventor); Grunwald, Thomas (Inventor); Ollert, Markus (Inventor) et al.

    Research output: Patent

  59. Published

    Extending the honeybee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5. / Van Vaerenbergh, Matthias; Cardoen, Dries; M. Formesyn, Ellen et al.

    In: Insect Molecular Biology, Vol. 22, No. 2, 2013, p. 199-210.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  60. Published

    Modulation of effector T cell responses by local depletion of complement component C3. / Bredehorst, Reinhard (Inventor); Grunwald, Thomas (Inventor); Ollert, Markus (Inventor) et al.

    Research output: Patent

  61. 2012
  62. Published

    An IgE epitope of Bet v 1 and fagales PR10 proteins as defined by a human monoclonal IgE. / Hecker, J.; Diethers, A.; Schulz, D. et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 67, No. 12, 01.12.2012, p. 1530-1537.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  63. Published

    Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8). / Kötzler, M.P.; Blank, S.; Bantleon, F.I. et al.

    In: B B A - General Subjects, Vol. 1820, No. 12, 01.12.2012, p. 1915-1925.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  64. Published

    Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy. / Spillner, E.; Greunke, K.; Seismann, H. et al.

    In: Biologicals, Vol. 40, No. 5, 01.09.2012, p. 313-322.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  65. Published

    Recombinant IgE antibody engineering to target EGFR. / Spillner, Edzard; Plum, Melanie; Blank, Simon et al.

    In: Cancer Immunology, Immunotherapy, Vol. 61, No. 9, 09.2012, p. 1565-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  66. Published

    Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model. / Wehr, Claudia; Müller, Fabian; Schüler, Julia et al.

    In: International Journal of Cancer, Vol. 131, No. 2, 15.07.2012, p. E10-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  67. Published

    Comparable IgE reactivity to natural and recombinant Api m 1 in cross-reactive carbohydrate determinant-negative patients with bee venom allergy. / Jakob, T.; Köhler, J.; Blank, S. et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 130, No. 1, 01.07.2012, p. 276-278.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  68. Published

    The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity. / Blank, S.; Bantleon, F.I.; Ollert, M. et al.

    In: Clinical and Experimental Allergy, Vol. 42, No. 6, 01.06.2012, p. 976-985.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  69. Published

    Formation of the immunogenic α1,3-fucose epitope : elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A. / Kötzler, Miriam P; Blank, Simon; Behnken, Henning N et al.

    In: Insect Biochemistry and Molecular Biology, Vol. 42, No. 2, 02.2012, p. 116-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  70. Published

    Potenzial, Fallstricke und aktueller Status der molekularen Diagnostik am Beispiel der Insektengiftallergie. / Spillner, E.; Blank, S.; Jakob, T.

    In: Allergo Journal, Vol. 21, No. 4, 01.01.2012, p. 249-256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  71. Published

    The putative serine protease inhibitor Api m 6 from Apis Mellifera venom : Recombinant and structural evaluation. / Michel, Y.; Ginglinger, H.; Blank, S. et al.

    In: Journal of Investigational Allergology and Clinical Immunology, Vol. 22, No. 7, 01.01.2012, p. 476-484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  72. 2011
  73. Published

    Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts. / Blank, S.; Seismann, H.; Michel, Y. et al.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 66, No. 10, 01.10.2011, p. 1322-1329.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  74. Published

    Detection of IgE to recombinant Api m 1 and rVes v 5 is valuable but not sufficient to distinguish bee from wasp venom allergy. / Sturm, G.J.; Bokanovic, D.; Aberer, W. et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 128, No. 1, 01.07.2011, p. 247-248.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  75. Published

    Reply. / Hofmann, S.C.; Pfender, N.; Weckesser, S. et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 128, No. 1, 01.07.2011, p. 248.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  76. Published

    Quantitation of serum IgE by using chimeras of human IgE receptor and avian immunoglobulin domains. / Braren, I.; Greunke, K.; Grunwald, T. et al.

    In: Analytical Biochemistry, Vol. 412, No. 2, 15.05.2011, p. 134-140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  77. Published

    Generation and epitope analysis of human monoclonal antibody isotypes with specificity for the timothy grass major allergen Phl p 5a. / Hecker, J.; Diethers, A.; Seismann, H. et al.

    In: Molecular Immunology, Vol. 48, No. 9-10, 01.05.2011, p. 1236-1244.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  78. Published

    Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. / Spillner, E.; Laursen, N.S.; Andersen, K.R. et al.

    In: E M B O Journal, Vol. 30, No. 3, 02.02.2011, p. 606-616.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  79. Published

    Close-up of the alpha-1,3-Gal epitope as defined by a monoclonal chimeric IgE and human serum using saturation transfer difference (STD) NMR. / Plum, Melanie; Michel, Yvonne; Wallach, Katharina et al.

    In: Journal of Biological Chemistry, Vol. 286, No. 50, 2011, p. 43103-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  80. Published

    Evaluation of different glycoforms of honeybee venom major allergen phospholipase A2 (Api m 1) produced in insect cells. / Blank, Simon; Seismann, Henning; Plum, Melanie et al.

    In: Protein and Peptide Letters, Vol. 18, No. 4, 2011, p. 415-422.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  81. Published

    Rekombinante Insektengift-Allergene: Ist das Bienen- oder doch das Wespengift schuld? / Jakob, Thilo; Blank, Simon; Spillner, Edzard et al.

    In: Der Deutsche Dermatologe, Vol. 59, 2011, p. 759-761.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  82. 2010
  83. Published

    Identification, recombinant expression, and characterization of the 100 kDa high molecular weight hymenoptera venom allergens Api m 5 and Ves v 3. / Blank, S.; Seismann, H.; Bockisch, B. et al.

    In: Journal of Immunology, Vol. 184, No. 9, 01.05.2010, p. 5403-5413.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  84. Published

    Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus. / Spillner, E.; Laursen, N.S.; Christensen, J.B. et al.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, No. 8, 23.02.2010, p. 3681-3686.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  85. Published

    Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells. / Binder, M.; Léchenne, B.; Ummanni, R. et al.

    In: P L o S One, Vol. 5, No. 12, e15992, 01.01.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  86. Published

    Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha-1,3-core fucosylation. / Seismann, Henning; Blank, Simon; Braren, Ingke et al.

    In: Molecular immunology, Vol. 47, No. 4, 01.2010, p. 799-808.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  87. Published

    Recombinant phospholipase A1 (Ves v 1) from yellow jacket venom for improved diagnosis of hymenoptera venom hypersensitivity. / Seismann, Henning; Blank, Simon; Cifuentes, Liliana et al.

    In: Clinical and Molecular Allergy, Vol. 8, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  88. 2009
  89. Published

    Establishment of hapten-specific monoclonal avian IgY by conversion of antibody fragments obtained from combinatorial libraries. / Deckers, Susanne; Braren, Ingke; Greunke, Kerstin et al.

    In: Biotechnology and Applied Biochemistry, Vol. 52, No. Pt 1, 01.2009, p. 79-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  90. Published

    Antibody compositions specific for IgE, IgG4 and IgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy. / Braren, Ingke (Inventor); Bredehorst, Reinhard (Inventor); Ollert, Markus (Inventor) et al.

    Research output: Patent

  91. 2008
  92. Published

    Recombinant IgY for improvement of immunoglobulin-based analytical applications. / Greunke, Kerstin; Braren, Ingke; Alpers, Iris et al.

    In: Clinical Biochemistry, Vol. 41, No. 14-15, 10.2008, p. 1237-44.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  93. 2007
  94. Published

    Comparative expression of different antibody formats in mammalian cells and Pichia pastoris. / Braren, Ingke; Greunke, Kerstin; Umland, Oliver et al.

    In: Biotechnology and Applied Biochemistry, Vol. 47, No. 4, 08.2007, p. 205-14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  95. Published

    Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries. / Braren, Ingke; Blank, Simon; Seismann, Henning et al.

    In: Clinical Chemistry, Vol. 53, No. 5, 05.2007, p. 837-44.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  96. Published

    Bivalent IgY antibody constructs for diagnostic and therapeutic applications. / Bredehorst, Reinhard (Inventor); Greunke, Kerstin (Inventor); Grunwald, Thomas (Inventor) et al.

    Research output: Patent

  97. Published

    Method for determining an unknown PNA [peptide nucleic acid] sequence and uses thereof. / Bredehorst, Reinhard (Inventor); Glökler, Jörn (Inventor); Grunwald, Thomas (Inventor) et al.

    Research output: Patent

  98. Published

    Purification of native and recombinant cobra venom factor using thiophilic adsorption chromatography. / Kölln, Johanna; Braren, Ingke; Bredehorst, Reinhard et al.

    In: Protein and Peptide Letters, Vol. 14, No. 5, 2007, p. 475-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  99. 2006
  100. Published

    Triosephosphate isomerase- and glyceraldehyde-3-phosphate dehydrogenase-reactive autoantibodies in the cerebrospinal fluid of patients with multiple sclerosis. / Kolln, Johanna; Ren, Hui-Min; Da, Reng-Rong et al.

    In: Journal of Immunology, Vol. 177, No. 8, 15.10.2006, p. 5652-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  101. Published

    Bivalent monoclonal IgY antibody formats by conversion of recombinant antibody fragments. / Greunke, Kerstin; Spillner, Edzard; Braren, Ingke et al.

    In: Journal of Biotechnology, Vol. 124, No. 2, 13.07.2006, p. 446-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  102. Published

    Molecular cloning and expression in insect cells of honeybee venom allergen acid phosphatase (Api m 3). / Grunwald, T.; Bockisch, B.; Spillner, E. et al.

    In: Journal of Allergy and Clinical Immunology, Vol. 117, No. 4, 01.04.2006, p. 848-854.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  103. Published

    High level expression of monomeric and dimeric human alpha1,3-fucosyltransferase V. / Münster, Jan; Ziegelmüller, Patrick; Spillner, Edzard et al.

    In: Journal of Biotechnology, Vol. 121, No. 4, 24.02.2006, p. 448-57.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  104. Published

    Inactivation of complement by recombinant human C3 derivatives. / Spillner, Edzard; Kölln, Johanna; Bredehorst, Reinhard.

    Current Topics in Complement. Vol. 586 2006. p. 347-60 (Advances in Experimental Medicine and Biology).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  105. 2005
  106. Published

    Engineering of human complement component C3 for catalytic inhibition of complement. / Kölln, Johanna; Bredehorst, Reinhard; Spillner, Edzard.

    In: Immunology Letters, Vol. 98, No. 1, 15.04.2005, p. 49-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  107. Published

    Malting barley grain non-specific lipid-transfer protein (ns-LTP) : Importance for grain protection. / Gorjanović, S.; Beljanski, M.V.; Pavlović, M. et al.

    In: Journal of the Institute of Brewing, Vol. 111, No. 2, 01.01.2005, p. 99-104.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  108. Published

    Complement depletion using recombinant human C3-derivatives. / Kölln, Johanna (Inventor); Spillner, Edzard (Inventor); Bredehorst, Reinhard (Inventor).

    Research output: Patent

  109. Published

    Immobilized stem-loop structured probes as conformational switches for enzymatic detection of microbial 16S rRNA. / Bockisch, Benjamin; Grunwald, Thomas; Spillner, Edzard et al.

    In: Nucleic Acids Research, Vol. 33, No. 11, e101, 2005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  110. Published

    Rapid detection of viruses using electrical biochips and anti-virion sera. / Łoś, M; Łoś, J M; Blohm, L et al.

    In: Letters in Applied Microbiology, Vol. 40, No. 6, 2005, p. 479-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  111. 2004
  112. Published

    Complement inactivation by recombinant human C3 derivatives. / Kölln, Johanna; Spillner, Edzard; Andrä, Jörg et al.

    In: Journal of Immunology, Vol. 173, No. 9, 01.11.2004, p. 5540-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  113. Published

    Functional analysis of Cobra Venom Factor/human C3 chimeras transiently expressed in mammalian cells. / Kölln, Johanna; Matzas, Mark; Jänner, Nathalie et al.

    In: Molecular Immunology, Vol. 41, No. 1, 05.2004, p. 19-28.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  114. 2003
  115. Published

    Paratope-based protein identification by antibody and peptide phage display. / Spillner, Edzard; Deckers, Susanne; Grunwald, Thomas et al.

    In: Analytical Biochemistry, Vol. 321, No. 1, 01.10.2003, p. 96-104.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  116. 2002
  117. Published

    Selektion und Expression von rekombinanten Antikörpern für analytische und therapeutische Applikationen. / Spillner, Edzard.

    Cuvillier Verlag, 2002. 260 p.

    Research output: Book/anthology/dissertation/report › Book › Research

  118. 1999
  119. Published

    Cleavage of palladium metallacycles by acids : A probe for the study of the cyclometalation reaction. / Cámpora, J.; López, J.A.; Palma, P. et al.

    In: Angewandte Chemie International Edition, Vol. 38, No. 1-2, 15.01.1999, p. 147-151.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  120. 1997
  121. Published

    pOVEX vector : Prokaryotic expression and purification of onchocerciasis vaccine candidate antigens as fusion proteins with the 24 kD Onchocerca volvulus glutathione S-transferase. / Liebau, E.; Spillner, E.; Henkle-Dührsen, K.

    In: Tropical Medicine & International Health, Vol. 2, No. 7, 01.01.1997, p. 691-694.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review