Aarhus University Seal / Aarhus Universitets segl

Edzard Spillner

  1. 2021
  2. E-pub ahead of print

    Carbohydrate Epitopes Currently Recognized as Targets for IgE Antibodies. / Platts-Mills, Thomas; Hilger, Christiane; Jappe, Uta; van Hage, Marianne; Gadermaier, Gabriele ; Spillner, Edzard; Lidholm, Jonas; Aalberse, Rob C. ; van Ree, Ronald; Goodman, Richard; Pomes, Anna.

    In: Allergy: European Journal of Allergy and Clinical Immunology, 02.03.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2020
  4. Published

    Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy. / Jensen, Rasmus K; Jabs, Frederic; Miehe, Michaela; Mølgaard, Brian; Pfützner, Wolfgang; Möbs, Christian; Spillner, Edzard; Andersen, Gregers R.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 75, No. 8, 08.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    In Silico Evaluation of the Binding Site of Fucosyltransferase 8 and First Attempts to Synthesize an Inhibitor with Drug-Like Properties. / Strecker, Claas; Bärenfänger, Melissa; Miehe, Michaela; Spillner, Edzard; Meyer, Bernd.

    In: ChemBioChem, Vol. 21, No. 13, 07.2020, p. 1923-1931.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The honey bee venom allergen Api m 10 displays one major IgE epitope, Api m 10160-174. / Rauber, Michèle; Roßbach, Antonia; Jung, Andreas; Müller, Sabine; Möbs, Christian; Pfützner, Wolfgang; Miehe, Michaela; Spillner, Edzard; Jakob, Thilo.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 75, No. 7, 07.2020, p. 1756-1759.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  7. Published

    The Honeybee Venom Major Allergen Api m 10 (Icarapin) and Its Role in Diagnostics and Treatment of Hymenoptera Venom Allergy. / Jakob, Thilo; Rauber, Michèle Myriam; Perez-Riverol, Amilcar; Spillner, Edzard; Blank, Simon.

    In: Current Allergy and Asthma Reports, Vol. 20, No. 9, 48, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  8. 2019
  9. Published

    Work-related allergic asthma : Clinical work-up of a 45-year old male working in animal feed producing industry. / Schmid, J. M.; Skjold, T.; Kolstad, H. A.; Miehe, M.; Spillner, E.; Hoffmann, H. J.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 74, 08.2019, p. 316-316.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  10. Published

    Inhibiting phosphatase SHIP-1 enhances suboptimal IgE-mediated activation of human blood basophils but inhibits IgE-mediated activation of cultured human mast cells. / Rasmussen, Pernille; Spillner, Edzard; Hoffmann, Hans Jürgen.

    In: Immunology Letters, Vol. 210, 01.06.2019, p. 40-46.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. 2018
  12. Published

    Characterization of the honeybee venom proteins C1q-like protein and PVF1 and their allergenic potential. / Russkamp, Dennis; Van Vaerenbergh, Matthias; Etzold, Stefanie; Eberlein, Bernadette; Darsow, Ulf; Schiener, Maximilian; De Smet, Lina; Absmaier, Magdalena; Biedermann, Tilo; Spillner, Edzard; Ollert, Markus; Jakob, Thilo; Schmidt-Weber, Carsten B.; de Graaf, Dirk C.; Blank, Simon.

    In: Toxicon, Vol. 150, 01.08.2018, p. 198-206.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Venoms of Neotropical wasps lack cross-reactive carbohydrate determinants enabling reliable protein-based specific IgE determination. / Riverol, Amilcar Perez; Miehe, Michaela; Jabs, Frederic; Seismann, Henning; Romani Fernandes, Luis G.; de Lima Zollner, Ricardo; Jakob, Thilo; Brochetto-Braga, Marcia R.; Spillner, Edzard.

    In: Journal of Allergy and Clinical Immunology, Vol. 141, No. 5, 05.2018, p. 1917-1919.e1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. / Jabs, Frederic; Plum, Melanie; Laursen, Nick Stub; Jensen, Rasmus Kjeldsen; Mølgaard, Brian; Miehe, Michaela; Mandolesi, Marco; Rauber, Michéle M.; Pfützner, Wolfgang; Jakob, Thilo; Möbs, Christian; Andersen, Gregers Rom; Spillner, Edzard.

    In: Nature Communications, Vol. 9, No. 1, 7, 02.01.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    AllergoOncology: Generating a canine anti-cancer IgE against the epidermal growth factor receptor. / Fazekas-Singer, Judit; Singer, Josef; Ilieva, Kristina M ; Matz, Miroslava; Herrmann, Ina; Spillner, Edzard; Karagiannis, Sophia N. ; Jensen-Jarolim, Erika.

    In: Journal of Allergy and Clinical Immunology, Vol. 142, No. 3, 2018, p. 973-976.e11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Phospholipase A1-based cross-reactivity among venoms of clinically relevant Hymenoptera from Neotropical and temperate regions. / Perez Riverol, Amilcar; Romani Fernandes, Luís G ; Musacchio Lasa, Alexis ; Aparecido dos Santos-Pinto, José Roberto ; Moitinho Abram, Débora ; Izuka Moraes, Gabriel Hideki; Jabs, Frederic; Miehe, Michaela; Seismann, Henning; Sergio Palma, Mario; de Lima Zollner, Ricardo; Spillner, Edzard; Brochetto-Braga, Marcia Regina.

    In: Molecular Immunology, Vol. 93, 2018, p. 87-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. 2017
  18. Published

    N-glycan maturation mutants in Lotus japonicus for basic and applied glycoprotein research. / Pedersen, Carina T.; Loke, Ian; Lorentzen, Andrea; Wolf, Sara; Kamble, Manoj; Kristensen, Sebastian K.; Munch, David; Radutoiu, Simona; Spillner, Edzard; Roepstorff, Peter; Thaysen-Andersen, Morten; Stougaard, Jens; Dam, Svend.

    In: Plant Journal, Vol. 91, No. 3, 01.08.2017, p. 394-407.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Comparing sensitivity of Hymenoptera allergen components on different diagnostic assay systems : Comparing apples and oranges. / Jakob, Thilo; Spillner, Edzard.

    In: Journal of Allergy and Clinical Immunology, Vol. 139, No. 3, 03.2017, p. 1066-1067.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Application of recombinant antigen 5 allergens from seven allergy-relevant Hymenoptera species in diagnostics. / Schiener, Maximilian; Eberlein, Bernadette; Moreno Aguilar, Carmen; Pietsch, G; Serrano, P; McIntyre, Mareike; Schwarze, Lea; Russkamp, Dennis; Biedermann, Tilo; Spillner, Edzard; Darsow, Ulf; Ollert, Markus; Schmidt-Weber, Carsten; Blank, Simon.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 72, No. 1, 01.2017, p. 98-108.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    AllergoOncology - the Impact of Allergy in Oncology. EAACI Position Paper. / Jensen-Jarolim, Erika; Bax, HJ; Bianchini, R; Capron, Monique ; Corrigan, C; Castells, M; Dombrovicz, D; Daniels-Wells, HR; Fazekas, J; Fiebiger, Edda; Gatault, S; Gould, Hanna; Janda, Josef; Josephs, DH; Karagiannis, Panos; Levi-Schaffer, F; Meshcheryakova, A; Mechtcheriakova, D; Mekori, Y; Mungenast, F; Nigro, EA; Penichet, Manuel F; Redegeld, Frank; Saul, L.; Singer, J; Spicer, JF; Siccardi, AG; Spillner, Edzard; Turner, MC; Untersmayr, Eva; Vangelista, L; Karagiannis, Sofia N.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 72, No. 6, 2017, p. 866-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Benefits and limitations of recombinant allergens in diagnostics of insect venom allergy. / Jakob, Thilo; Blank, Simon; Spillner, Edzard.

    Molecular Allergy Diagnostics. ed. / J. Kleine-Tebbe; T. Jakob. Springer, 2017. p. 341-362.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  23. Published

    Component resolved diagnostics for Hymenoptera venom allergy. / Jakob, Thilo; Müller, Ulrich; Helbling, Arthur; Spillner, Edzard.

    In: Current Opinion in Allergy and Clinical Immunology, Vol. 17, No. 5, 2017, p. 363-372.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Diagnostics in hymenoptera venom allergy: Current concepts and developments with special focus on molecular allergy diagnostics. / Jakob, Thilo; Rafei-Shamsabadi, David; Spillner, Edzard; Müller, Sabine.

    In: Allergo Journal International, Vol. 26, No. 3, 2017, p. 93-105.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. 2016
  26. Published

    Human IgE is efficiently produced in glycosylated and biologically active form in lepidopteran cells. / Bantleon, Frank; Wolf, Sara; Seismann, Henning; Dam, Svend Secher; Lorentzen, Andrea; Miehe, Michaela; Jabs, Frederic; Jakob, Thilo; Plum, Melanie; Spillner, Edzard.

    In: Molecular Immunology, Vol. 72, 2016, p. 49-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains. / Offermann, Nadine; Plum, Melanie; Hübner, Uschi; Rathloff, K.; Braren, I.; Fooke, Margrit; Spillner, Edzard.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 71, No. 12, 2016, p. 1794-1799.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    IgE als Zielstruktur für therapeutische Intervention. / Jakob, Thilo; Spillner, Edzard; Lamers, Marinus.

    Allergologie. ed. / Tilo Biedermann; Harald Renz; Werner Heppt; Martin Röcken. Springer, 2016. p. 631-640.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  29. Published

    Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. / Frick, Marcel; Fischer, Jörg; Helbing, Arthur; Ruëff, Franziska; Wieczorek, Dorothea; Ollert, Markus; Pfützner, Wolfgang; Müller, Sabine; Huss-Marp, Johannes; Dorn, Britta; Biedermann, Tilo; Lidholm, Jonas; Rücker, Gerta; Bantleon, Frank; Miehe, Michaela; Spillner, Edzard; Jakob, Thilo.

    In: Journal of Allergy and Clinical Immunology, Vol. 138, No. 6, 2016, p. 1663-1671e9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Recombinant allergens as a major step in molecular allergology: Scientific and methodological considerations. / Spillner, Edzard.

    Slovenian Pneumology and Allergology Congress joined with Golnik Symposium and Balkan Pneumology Meeting: Personalised Medicine in Respiratory and Immunologic Diseases - Book of Abstacts. ed. / Mitja Kosnik; Robert Marcun. Golnik : University Clinic of Respiratory and Allergic Diseases, Golnik, 2016. p. 77-81.

    Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  31. 2015
  32. Published

    Structure of the omalizumab Fab. / Jensen, Rasmus K; Plum, Melanie; Tjerrild, Luna; Jakob, Thilo; Spillner, Edzard; Andersen, Gregers Rom.

    In: Acta Crystallographica Section F: Structural Biology Communications, Vol. 71, No. Pt 4, 04.2015, p. 419-426.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Decline of Ves v 5-specific blocking capacity in wasp venom-allergic patients after stopping allergen immunotherapy. / Möbs, Christian; Müller, Jan; Rudzio, Annika; Pickert, Julia; Blank, Simon; Jakob, Thilo; Spillner, Edzard; Pfützner, Wolfgang.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 6, 07.03.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Diagnostik der Insektengiftallergie: vom Extrakt zum Molekül. / Spillner, Edzard.

    In: Spitzenforschung in der Allergologie, Vol. 2015, 2015, p. 92-93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  35. Published

    IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology. / Van Vaerenbergh, Matthias; de Smet, Lina; Rafei-Shamsabadi, David; Blank, Simon; Spillner, Edzard; Ebo, Didier; Devreese, Bart; Jakob, Thilo; C. de Graaf, Dirk.

    In: Molecular Immunology, Vol. 63, No. 2, 2015, p. 449-455.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Optimierte Diagnostik der Insektengiftallergie durch rekombinante Allergene. / Jakob, Thilo; Blank, Simon; Spillner, Edzard.

    Molekulare Allergiediagnostik. ed. / Jörg Kleine-Tebbe; Thilo Jakob. Springer, 2015. p. 257-275.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  37. Published

    rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom. / Frick, Marcel; Müller, Sabine; Bantleon, Frank; Hus-Marp, Johannes; Lidholm, Jonas; Spillner, Edzard; Jakob, Thilo.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 70, No. 12, 2015, p. 1665-1668.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2014
  39. Published

    Aktueller Stand und neue Entwicklungen in der Diagnostik mit rekombinanten Insektengiftallergenen. / Jakob, Thilo; Müller, Sabine; Rafei-Shamsabadi, David; Bantleon, Frank; Spillner, Edzard.

    In: Allergologie, Vol. 37, No. 9, 09.2014, p. 352-361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Recombinant allergens rarely allow identification of Hymenoptera venom-allergic patients with negative specific IgE to whole venom preparations. / Rafei-Shamsabadi, David; Müller, Sabine; Pfützner, Wolfgang; Spillner, Edzard; Rueff, Franziska; Jakob, Thilo.

    In: Journal of Allergy and Clinical Immunology, Vol. 134, No. 2, 08.2014, p. 493-494.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients. / Singer, Josef; Fazekas, Judith; Wang, Wei; Weichselbaumer, Marlene; Matz, Miroslawa; Mader, Alexander; Steinfellner, Willibald; Meitz, Sarah; Mechticheriakova, Diana; Sobanov, Juri; Willmann, Michael; Stockner, Thomas; Spillner, Edzard; Kunert, Renate; Jensen-Jarolim, Erika.

    In: Molecular Cancer Therapeutics, Vol. 13, No. 7, 07.2014, p. 1777-1790.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Selective local inhibition of TNFR1-mediated functions at the site of antigen/allergen presentation. / Bredehorst, Reinhard (Inventor); Grunwald, Thomas (Inventor); Ollert, M.W. (Inventor); Schmidt-Weber, Carsten (Inventor); Spillner, Edzard (Inventor).

    Jun 25, 2014.

    Research output: Patent

  43. Published

    Component resolution reveals additional major allergens in patients with honeybee venom allergy. / Köhler, Julian; Blank, Simon ; Müller, Sabine; Bantleon, Frank ; Frick, Marcel ; Huss-Marp, Johannes ; Lidholm, Jonas ; Spillner, Edzard; Jakob, Thilo .

    In: Journal of Allergy and Clinical Immunology, Vol. 133, No. 5, 05.2014, p. 1383-1389.e6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Basophil activation test using recombinant allergens: highly specific diagnostic method complementing routine tests in wasp venom allergy. / Balzer, Lukas; Pennino, Davide; Blank, Simon; Seismann, Henning; Darsow, Ulf; Schnedler, Mathias; McIntyre, Mareike; Ollert, Markus; Durham, Stephen R; Spillner, Edzard; Ring, Johannes; Cifuentes, Liliana.

    In: P L o S One, Vol. 9, No. 10, 2014, p. e108619.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Hymenoptera allergens: from venom to ”venome”. / Spillner, Edzard; Blank, Simon; Jakob, Thilo.

    In: Frontiers in Immunology, Vol. 5, No. 77, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Identification of hymenoptera venom-allergic patients with negative specific IgE to venom extract by using recombinant allergens. / Cifuentes, Liliana ; Vosseler, Sebastian ; Blank, Simon ; Seismann, Henning ; Grunwald, Thomas ; Darsow, Ulf ; Bredehorst, Reinhard ; Mempel, Martin ; Spillner, Edzard; Ring, Johannes ; Ollert, Markus .

    In: Journal of Allergy and Clinical Immunology, Vol. 133, No. 3, 2014, p. 909-910.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. 2013
  48. Published

    Donor assists acceptor binding and catalysis of human α1,6-fucosyltransferase. / Kötzler, Miriam P; Blank, Simon; Bantleon, Frank I; Wienke, Martin; Spillner, Edzard; Meyer, Bernd.

    In: A C S Chemical Biology, Vol. 8, No. 8, 16.08.2013, p. 1830-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Vitellogenins Are New High Molecular Weight Components and Allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris Venom. / Blank, S.; Seismann, H.; McIntyre, M.; Ollert, M.; Wolf, S.; Bantleon, F.I.; Spillner, E.

    In: P L o S One, Vol. 8, No. 4, 23.04.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Polistes species venom is devoid of carbohydrate-based cross-reactivity and allows interference-free diagnostics. / Blank, Simon; Neu, Charles; Hasche, Daniel; Bantleon, Frank I; Jakob, Thilo; Spillner, Edzard.

    In: The Journal of allergy and clinical immunology, Vol. 131, No. 4, 04.2013, p. 1239-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. Published

    Controlled activation of complement components for use as endogenous adjuvant. / Bredehorst, Reinhard (Inventor); Grunwald, Thomas (Inventor); Ollert, Markus (Inventor); Schmidt-Weber, Carsten (Inventor); Spillner, Edzard (Inventor).

    Research output: Patent

  52. Published

    Extending the honeybee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5. / Van Vaerenbergh, Matthias; Cardoen, Dries; M. Formesyn, Ellen; Brunain, Marleen; Van Driessche, Gonzalez; Blank, Simon; Spillner, Edzard; Verleyen, Peter; Wenseleers, Tom; Schoofs, Liliane; Devreese, Bart; C. de Graaf, Dirk.

    In: Insect Molecular Biology, Vol. 22, No. 2, 2013, p. 199-210.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Modulation of effector T cell responses by local depletion of complement component C3. / Bredehorst, Reinhard (Inventor); Grunwald, Thomas (Inventor); Ollert, Markus (Inventor); Schmidt-Weber, Carsten (Inventor); Spillner, Edzard (Inventor).

    Research output: Patent

  54. 2012
  55. Published

    An IgE epitope of Bet v 1 and fagales PR10 proteins as defined by a human monoclonal IgE. / Hecker, J.; Diethers, A.; Schulz, D.; Sabri, A.; Plum, Melanie; Michel, Y.; Mempel, M.; Ollert, M.; Jakob, T.; Blank, S.; Braren, I.; Spillner, E.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 67, No. 12, 01.12.2012, p. 1530-1537.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8). / Kötzler, M.P.; Blank, S.; Bantleon, F.I.; Spillner, E.; Meyer, B.

    In: B B A - General Subjects, Vol. 1820, No. 12, 01.12.2012, p. 1915-1925.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy. / Spillner, E.; Greunke, K.; Seismann, H.; Blank, S.; Braren, I.; du Plessis, D.

    In: Biologicals, Vol. 40, No. 5, 01.09.2012, p. 313-322.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Recombinant IgE antibody engineering to target EGFR. / Spillner, Edzard; Plum, Melanie; Blank, Simon; Miehe, Michaela; Singer, Josef; Braren, Ingke.

    In: Cancer Immunology, Immunotherapy, Vol. 61, No. 9, 09.2012, p. 1565-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model. / Wehr, Claudia; Müller, Fabian; Schüler, Julia; Tomann, Tina; Nitschke, Claudia; Seismann, Henning; Spillner, Edzard; Klingner, Kerstin; Schneider-Merck, Tanja; Binder, Mascha; Fiebig, Heinz-Herbert; Mertelsmann, Roland; Trepel, Martin.

    In: International Journal of Cancer, Vol. 131, No. 2, 15.07.2012, p. E10-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Comparable IgE reactivity to natural and recombinant Api m 1 in cross-reactive carbohydrate determinant-negative patients with bee venom allergy. / Jakob, T.; Köhler, J.; Blank, S.; Spillner, E.; Magnusson, U.; Lidholm, J.; Huss-Marp, J.

    In: Journal of Allergy and Clinical Immunology, Vol. 130, No. 1, 01.07.2012, p. 276-278.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity. / Blank, S.; Bantleon, F.I.; Ollert, M.; McIntyre, M.; Spillner, E.

    In: Clinical and Experimental Allergy, Vol. 42, No. 6, 01.06.2012, p. 976-985.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    Formation of the immunogenic α1,3-fucose epitope : elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A. / Kötzler, Miriam P; Blank, Simon; Behnken, Henning N; Alpers, Dirk; Bantleon, Frank I; Spillner, Edzard; Meyer, Bernd.

    In: Insect Biochemistry and Molecular Biology, Vol. 42, No. 2, 02.2012, p. 116-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Potenzial, Fallstricke und aktueller Status der molekularen Diagnostik am Beispiel der Insektengiftallergie. / Spillner, E.; Blank, S.; Jakob, T.

    In: Allergo Journal, Vol. 21, No. 4, 01.01.2012, p. 249-256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. Published

    The putative serine protease inhibitor Api m 6 from Apis Mellifera venom : Recombinant and structural evaluation. / Michel, Y.; Ginglinger, H.; Blank, S.; McIntyre, M.; Ollert, M.; Cifuentes, L.; Spillner, E.

    In: Journal of Investigational Allergology and Clinical Immunology, Vol. 22, No. 7, 01.01.2012, p. 476-484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. 2011
  66. Published

    Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts. / Blank, S.; Seismann, H.; Michel, Y.; McIntyre, M.; Cifuentes, L.; Braren, I.; Grunwald, T.; Darsow, U.; Ring, J.; Bredehorst, R.; Ollert, M.; Spillner, E.

    In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 66, No. 10, 01.10.2011, p. 1322-1329.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    Detection of IgE to recombinant Api m 1 and rVes v 5 is valuable but not sufficient to distinguish bee from wasp venom allergy. / Sturm, G.J.; Bokanovic, D.; Aberer, W.; Hemmer, W.; Hawranek, T.; Lang, R.; Ollert, M.; Spillner, E.; Blank, S.

    In: Journal of Allergy and Clinical Immunology, Vol. 128, No. 1, 01.07.2011, p. 247-248.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    Reply. / Hofmann, S.C.; Pfender, N.; Weckesser, S.; Jakob, T.; Blank, S.; Spillner, E.; Huss-Marp, J.

    In: Journal of Allergy and Clinical Immunology, Vol. 128, No. 1, 01.07.2011, p. 248.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Quantitation of serum IgE by using chimeras of human IgE receptor and avian immunoglobulin domains. / Braren, I.; Greunke, K.; Grunwald, T.; Pilette, C.; Mempel, M.; Bredehorst, R.; Ring, J.; Spillner, E.; Ollert, M.

    In: Analytical Biochemistry, Vol. 412, No. 2, 15.05.2011, p. 134-140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Generation and epitope analysis of human monoclonal antibody isotypes with specificity for the timothy grass major allergen Phl p 5a. / Hecker, J.; Diethers, A.; Seismann, H.; Michel, Y.; Plum, Melanie; Bredehorst, R.; Blank, S.; Etzold, S.; Braren, I.; Spillner, E.

    In: Molecular Immunology, Vol. 48, No. 9-10, 01.05.2011, p. 1236-1244.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  71. Published

    Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. / Spillner, E.; Laursen, N.S.; Andersen, K.R.; Sottrup-Jensen, L.; Andersen, G.R.; Braren, I.

    In: E M B O Journal, Vol. 30, No. 3, 02.02.2011, p. 606-616.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. Published

    Close-up of the alpha-1,3-Gal epitope as defined by a monoclonal chimeric IgE and human serum using saturation transfer difference (STD) NMR. / Plum, Melanie; Michel, Yvonne; Wallach, Katharina; Raiber, Tim; Blank, Simon; Bantleon, Frank I.; Diethers, Andrea; Greunke, Kerstin; Braren, Ingke; Hackl, Thomas; Meyer, Bernd; Spillner, Edzard.

    In: Journal of Biological Chemistry, Vol. 286, No. 50, 2011, p. 43103-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    Evaluation of different glycoforms of honeybee venom major allergen phospholipase A2 (Api m 1) produced in insect cells. / Blank, Simon; Seismann, Henning; Plum, Melanie; Greunke, Kerstin; Grunwald, Thomas; Bredehorst, Reinhard; Ollert, Markus; Braren, Ingke; Spillner, Edzard.

    In: Protein and Peptide Letters, Vol. 18, No. 4, 2011, p. 415-422.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Rekombinante Insektengift-Allergene: Ist das Bienen- oder doch das Wespengift schuld? / Jakob, Thilo; Blank, Simon; Spillner, Edzard; Ollert, Markus.

    In: Der Deutsche Dermatologe, Vol. 59, 2011, p. 759-761.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. 2010
  76. Published

    Identification, recombinant expression, and characterization of the 100 kDa high molecular weight hymenoptera venom allergens Api m 5 and Ves v 3. / Blank, S.; Seismann, H.; Bockisch, B.; Rühl, D.; Bredehorst, R.; Braren, I.; Grunwald, T.; Cifuentes, L.; McIntyre, M.; Ring, J.; Ollert, M.W.; Spillner, E.

    In: Journal of Immunology, Vol. 184, No. 9, 01.05.2010, p. 5403-5413.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus. / Spillner, E.; Laursen, N.S.; Christensen, J.B.; Jensen, M.; Fredslund, F.; Sottrup-Jensen, L.; Andersen, G.R.; Gordon, N.; Hermans, S.; Lorenz, N.; Jackson, N.; Fraser, J.D.; Wines, B.; Bjerre, M.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, No. 8, 23.02.2010, p. 3681-3686.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells. / Binder, M.; Léchenne, B.; Ummanni, R.; Balabanov, S.; Trepel, M.; Scharf, C.; Trusch, M.; Schlüter, H.; Braren, I.; Spillner, E.

    In: P L o S One, Vol. 5, No. 12, e15992, 01.01.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha-1,3-core fucosylation. / Seismann, Henning; Blank, Simon; Braren, Ingke; Greunke, Kerstin; Cifuentes, Liliana; Grunwald, Thomas; Bredehorst, Reinhard; Ollert, Markus; Spillner, Edzard.

    In: Molecular immunology, Vol. 47, No. 4, 01.2010, p. 799-808.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  80. Published

    Recombinant phospholipase A1 (Ves v 1) from yellow jacket venom for improved diagnosis of hymenoptera venom hypersensitivity. / Seismann, Henning; Blank, Simon; Cifuentes, Liliana; Braren, Ingke; Bredehorst, Reinhard; Grunwald, Thomas; Ollert, Markus; Spillner, Edzard.

    In: Clinical and Molecular Allergy, Vol. 8, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. 2009
  82. Published

    Establishment of hapten-specific monoclonal avian IgY by conversion of antibody fragments obtained from combinatorial libraries. / Deckers, Susanne; Braren, Ingke; Greunke, Kerstin; Meyer, Nadine; Rühl, Dana; Bredehorst, Reinhard; Spillner, Edzard.

    In: Biotechnology and Applied Biochemistry, Vol. 52, No. Pt 1, 01.2009, p. 79-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Antibody compositions specific for IgE, IgG4 and IgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy. / Braren, Ingke (Inventor); Bredehorst, Reinhard (Inventor); Ollert, Markus (Inventor); Grunwald, Thomas (Inventor); Spillner, Edzard (Inventor); Ring, Johannes (Inventor).

    Research output: Patent

  84. 2008
  85. Published

    Recombinant IgY for improvement of immunoglobulin-based analytical applications. / Greunke, Kerstin; Braren, Ingke; Alpers, Iris; Blank, Simon; Sodenkamp, Jan; Bredehorst, Reinhard; Spillner, Edzard.

    In: Clinical Biochemistry, Vol. 41, No. 14-15, 10.2008, p. 1237-44.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. 2007
  87. Published

    Comparative expression of different antibody formats in mammalian cells and Pichia pastoris. / Braren, Ingke; Greunke, Kerstin; Umland, Oliver; Deckers, Susanne; Bredehorst, Reinhard; Spillner, Edzard.

    In: Biotechnology and Applied Biochemistry, Vol. 47, No. 4, 08.2007, p. 205-14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries. / Braren, Ingke; Blank, Simon; Seismann, Henning; Deckers, Susanne; Ollert, Markus; Grunwald, Thomas; Spillner, Edzard.

    In: Clinical Chemistry, Vol. 53, No. 5, 05.2007, p. 837-44.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. Published

    Bivalent IgY antibody constructs for diagnostic and therapeutic applications. / Bredehorst, Reinhard (Inventor); Greunke, Kerstin (Inventor); Grunwald, Thomas (Inventor); Spillner, Edzard (Inventor).

    Research output: Patent

  90. Published

    Method for determining an unknown PNA [peptide nucleic acid] sequence and uses thereof. / Bredehorst, Reinhard (Inventor); Glökler, Jörn (Inventor); Grunwald, Thomas (Inventor); Matzas, Mark (Inventor); Spillner, Edzard (Inventor).

    Research output: Patent

  91. Published

    Purification of native and recombinant cobra venom factor using thiophilic adsorption chromatography. / Kölln, Johanna; Braren, Ingke; Bredehorst, Reinhard; Spillner, Edzard.

    In: Protein and Peptide Letters, Vol. 14, No. 5, 2007, p. 475-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. 2006
  93. Published

    Triosephosphate isomerase- and glyceraldehyde-3-phosphate dehydrogenase-reactive autoantibodies in the cerebrospinal fluid of patients with multiple sclerosis. / Kolln, Johanna; Ren, Hui-Min; Da, Reng-Rong; Zhang, Yiping; Spillner, Edzard; Olek, Michael; Hermanowicz, Neal; Hilgenberg, Lutz G; Smith, Martin A; van den Noort, Stanley; Qin, Yufen.

    In: Journal of Immunology, Vol. 177, No. 8, 15.10.2006, p. 5652-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  94. Published

    Bivalent monoclonal IgY antibody formats by conversion of recombinant antibody fragments. / Greunke, Kerstin; Spillner, Edzard; Braren, Ingke; Seismann, Henning; Kainz, Sabine; Hahn, Ulrich; Grunwald, Thomas; Bredehorst, Reinhard.

    In: Journal of Biotechnology, Vol. 124, No. 2, 13.07.2006, p. 446-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    Molecular cloning and expression in insect cells of honeybee venom allergen acid phosphatase (Api m 3). / Grunwald, T.; Bockisch, B.; Spillner, E.; Bredehorst, R.; Ring, J.; Ollert, M.W.

    In: Journal of Allergy and Clinical Immunology, Vol. 117, No. 4, 01.04.2006, p. 848-854.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  96. Published

    High level expression of monomeric and dimeric human alpha1,3-fucosyltransferase V. / Münster, Jan; Ziegelmüller, Patrick; Spillner, Edzard; Bredehorst, Reinhard.

    In: Journal of Biotechnology, Vol. 121, No. 4, 24.02.2006, p. 448-57.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  97. Published

    Inactivation of complement by recombinant human C3 derivatives. / Spillner, Edzard; Kölln, Johanna; Bredehorst, Reinhard.

    Current Topics in Complement. Vol. 586 2006. p. 347-60 (Advances in Experimental Medicine and Biology).

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  98. 2005
  99. Published

    Engineering of human complement component C3 for catalytic inhibition of complement. / Kölln, Johanna; Bredehorst, Reinhard; Spillner, Edzard.

    In: Immunology Letters, Vol. 98, No. 1, 15.04.2005, p. 49-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    Malting barley grain non-specific lipid-transfer protein (ns-LTP) : Importance for grain protection. / Gorjanović, S.; Beljanski, M.V.; Pavlović, M.; Spillner, E.; Gorjanović, R.; Gojgić-Cvijanović, G.

    In: Journal of the Institute of Brewing, Vol. 111, No. 2, 01.01.2005, p. 99-104.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    Complement depletion using recombinant human C3-derivatives. / Kölln, Johanna (Inventor); Spillner, Edzard (Inventor); Bredehorst, Reinhard (Inventor).

    Research output: Patent

  102. Published

    Immobilized stem-loop structured probes as conformational switches for enzymatic detection of microbial 16S rRNA. / Bockisch, Benjamin; Grunwald, Thomas; Spillner, Edzard; Bredehorst, Reinhard.

    In: Nucleic Acids Research, Vol. 33, No. 11, e101, 2005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  103. Published

    Rapid detection of viruses using electrical biochips and anti-virion sera. / Łoś, M; Łoś, J M; Blohm, L; Spillner, E; Grunwald, T; Albers, J; Hintsche, R; Wegrzyn, G.

    In: Letters in Applied Microbiology, Vol. 40, No. 6, 2005, p. 479-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. 2004
  105. Published

    Complement inactivation by recombinant human C3 derivatives. / Kölln, Johanna; Spillner, Edzard; Andrä, Jörg; Klensang, Katrin; Bredehorst, Reinhard.

    In: Journal of Immunology, Vol. 173, No. 9, 01.11.2004, p. 5540-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. Published

    Functional analysis of Cobra Venom Factor/human C3 chimeras transiently expressed in mammalian cells. / Kölln, Johanna; Matzas, Mark; Jänner, Nathalie; Mix, Thorsten; Klensang, Katrin; Bredehorst, Reinhard; Spillner, Edzard.

    In: Molecular Immunology, Vol. 41, No. 1, 05.2004, p. 19-28.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. 2003
  108. Published

    Paratope-based protein identification by antibody and peptide phage display. / Spillner, Edzard; Deckers, Susanne; Grunwald, Thomas; Bredehorst, Reinhard.

    In: Analytical Biochemistry, Vol. 321, No. 1, 01.10.2003, p. 96-104.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. 2002
  110. Published

    Selektion und Expression von rekombinanten Antikörpern für analytische und therapeutische Applikationen. / Spillner, Edzard.

    Cuvillier Verlag, 2002. 260 p.

    Research output: Book/anthology/dissertation/reportBookResearch

  111. 1999
  112. Published

    Cleavage of palladium metallacycles by acids : A probe for the study of the cyclometalation reaction. / Cámpora, J.; López, J.A.; Palma, P.; Spillner, E.; Carmona, E.; Valerga, P.

    In: Angewandte Chemie International Edition, Vol. 38, No. 1-2, 15.01.1999, p. 147-151.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  113. 1997
  114. Published

    pOVEX vector : Prokaryotic expression and purification of onchocerciasis vaccine candidate antigens as fusion proteins with the 24 kD Onchocerca volvulus glutathione S-transferase. / Liebau, E.; Spillner, E.; Henkle-Dührsen, K.

    In: Tropical Medicine & International Health, Vol. 2, No. 7, 01.01.1997, p. 691-694.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review