Research output per year
Research output per year
Personal profile
Profile
I am a specialist in clinical biochemistry and work particularly with the following areas:
- Drug monitoring (TDM)
- Analysis of illicit substances
- The pre-analytical process
I am interested in the use of drug monitoring of, for example, newer medications that find their way into monitoring with the aim of, for example, reducing side effect profiles. A prerequisite for monitoring is good therapeutic intervals that allow assessment of plasma concentrations of the drugs studied.
Job responsibilities
In addition to responsibility for drug monitoring and drug of abuse analysis, I also work with quality assurance of the pre-analytical process in clinical biochemistry on a daily basis. This can be in relation to procedures such as venipuncture or ECG recording, but also analyte specific. Optimizing the pre-analysis can significantly improve the analytical result of a given analysis.
Areas of expertise
- Therapeutic Drug Monitoring
- Drugs of Abuse Testing
- Clinical Biochemistry
- Preanalytical Phase of Laboratory
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Development and validation of an LC-MS/MS method for quantification of Osimertinib and its two metabolites AZ7550 and AZ5104 in human plasma including long-time storage
Greibe, E., Sorensen, B., Meldgaard, P. & Hoffmann-Lücke, E., 15 Mar 2025, In: Journal of Pharmaceutical and Biomedical Analysis. 255, 116662.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
3 Citations (Scopus) -
Evaluation of antiseizure medication concentration ranges in blood samples using an automated big data approach
Nersesjan, M., Hoffmann-Lücke, E., Greibe, E., Aaslo, P. H., Bak, L. K., Pedersen, L. E., Fruekilde, P. B. N., Stark, A., Christensen, J., Brønden, A. & Larsen, J. B., Jun 2025, In: Epilepsia. 66, 6, p. 1888-1898 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access1 Citation (Scopus) -
Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKI) for optimized outcome in patients with metastatic renal cell carcinoma. The TKI-TDM Trial. Study protocol
Henriksen, J., Andersen, C. U., Donskov, F., Hoffmann-Lücke, E., Greibe, E. & Fristrup, N., 2 Jun 2025, In: Acta Oncologica. 64, p. 729-733 5 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Timing and dosage of intrapartum prophylactic penicillin for preventing early-onset group B streptococcal disease: Assessing maternal and umbilical cord blood concentration
Nielsen, S. Y., Hoffmann-Lücke, E., Henriksen, T. B., Hartvigsen, C. M., Helmig, R. B., Khalil, M. R., Møller, J. K., Pedersen, L. H., Murra, M. & Greibe, E., 1 Mar 2025, In: Archives of Disease in Childhood: Fetal and Neonatal Edition. 110, 2, p. F128-F132 fetalneonatal-2024-326986.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access5 Citations (Scopus) -
Automated Interlaboratory Comparison of Therapeutic Drug Monitoring Data and Its Use for Evaluation of Published Therapeutic Reference Ranges
Larsen, J. B., Hoffmann-Lücke, E., Aaslo, P. H., Jørgensen, N. R. & Greibe, E., Feb 2023, In: Pharmaceutics. 15, 2, 673.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access4 Citations (Scopus)