Research output per year
Research output per year
Search results
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2020
Crystal and solution structures of fragments of the human leucocyte common antigen-related protein
Vilstrup, J., Simonsen, A., Birkefeldt, T., Strandbygård, D., Lyngsø, J., Pedersen, J. S. & Thirup, S., May 2020, In: Acta crystallographica Section D: Structural biology . 76, p. 406-417 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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2017
Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin
Januliene, D., Andersen, J. L., Nielsen, J. A., Quistgaard, E. M., Hansen, M., Strandbygaard, D., Moeller, A., Petersen, C. M., Madsen, P. & Thirup, S. S., 5 Dec 2017, In: Structure. 25, 12, p. 1809-1819.e3 14 p., 12.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin
Andersen, J. L., Lindberg, S., Langgård, M., Maltas, P. J., Rønn, L. C. B., Bundgaard, C., Strandbygaard, D., Thirup, S. & Watson, S. P., 1 Jun 2017, In: Bioorganic & Medicinal Chemistry Letters. 27, 11, p. 2629-2633 5 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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2014
Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex
Andersen, J. L., Schrøder, T. J., Christensen, S., Strandbygård, D. J., Pallesen, L. T., Garcia Alai, M. M., Lindberg, S., Langgård, M., Eskildsen, J. C., David, L., Tagmose, L., Simonsen, K. B., Maltas, P. J., Rønn, L. C. B., de Jong, I. E. M., Malik, I. J., Egebjerg, J., Karlsson, J. J., Uppalanchi, S. & Sakumudi, D. R. & 3 others, , Feb 2014, In: Acta Crystallographica. Section D: Biological Crystallography. 70, Part 2, p. 451-460 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin
Schrøder, T. J., Christensen, S., Lindberg, S., Langgård, M., David, L., Maltas, P. J., Eskildsen, J., Jacobsen, J., Tagmose, L., Simonsen, K. B., Biilmann Rønn, L. C., de Jong, I. E. M., Malik, I. J., Karlsson, J.-J., Bundgaard, C., Egebjerg, J., Stavenhagen, J. B., Strandbygård, D., Thirup, S. S. & Andersen, J. L. & 6 others, , 1 Jan 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 1, p. 177-180 4 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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2011
Mouse models for FHM2 and RDP - mutations in Na/K-ATPase isoforms give rise to distinct neurological diseases
Bøttger, P., Heuck, A., Strandbygård, D. J., Nissen, P. & Lykke-Hartmann, K., 2011.Research output: Contribution to conference › Poster › Communication
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2008
Transgenic mouse models for two inherited neuronal diseases
Bøttger, P., Tracz, Z., Pelc, M., Albertsen, M., Strandbygård, D. J., Romero-Ramos, M. & Lykke-Andersen, K., 2008.Research output: Contribution to conference › Poster › Research
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2007
Expression of the RAI gene is conducive to apoptosis: studies of induction and interference
Laska, M. J., Strandbygård, D. J., Kjeldgaard, A., Mains, M., Corydon, T. J., Memon, A. A., Sørensen, B. S., Vogel, U., Jensen, U. B. & Nexø, B. A., 2007, In: Experimental Cell Research. 313, 12, p. 2611-21 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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2004
Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1
Andersen, J. B., Strandbygård, D. J., Hartmann, R. & Justesen, J., Feb 2004, In: European Journal of Biochemistry. 271, 3, p. 628-636 9 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review