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Dive into the research topics where Dorthe Strandbygård is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 1 Finished
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Struktur af sortilin
Strandbygård, D. (Participant), Thirup, S. S. (Participant), Kristensen, K. M. (Participant), Januliene, D. (Participant), Garcia Alai, M. M. (Participant) & Andersen, J. L. (Participant)
01/05/2012 → 01/12/2013
Project: Research
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Crystal and solution structures of fragments of the human leucocyte common antigen-related protein
Vilstrup, J., Simonsen, A., Birkefeldt, T., Strandbygård, D., Lyngsø, J., Pedersen, J. S. & Thirup, S., May 2020, In: Acta crystallographica Section D: Structural biology . 76, p. 406-417 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin
Januliene, D., Andersen, J. L., Nielsen, J. A., Quistgaard, E. M., Hansen, M., Strandbygaard, D., Moeller, A., Petersen, C. M., Madsen, P. & Thirup, S. S., 5 Dec 2017, In: Structure. 25, 12, p. 1809-1819.e3 14 p., 12.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin
Andersen, J. L., Lindberg, S., Langgård, M., Maltas, P. J., Rønn, L. C. B., Bundgaard, C., Strandbygaard, D., Thirup, S. & Watson, S. P., 1 Jun 2017, In: Bioorganic & Medicinal Chemistry Letters. 27, 11, p. 2629-2633 5 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex
Andersen, J. L., Schrøder, T. J., Christensen, S., Strandbygård, D. J., Pallesen, L. T., Garcia Alai, M. M., Lindberg, S., Langgård, M., Eskildsen, J. C., David, L., Tagmose, L., Simonsen, K. B., Maltas, P. J., Rønn, L. C. B., de Jong, I. E. M., Malik, I. J., Egebjerg, J., Karlsson, J. J., Uppalanchi, S. & Sakumudi, D. R. & 3 others, , Feb 2014, In: Acta Crystallographica. Section D: Biological Crystallography. 70, Part 2, p. 451-460 10 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin
Schrøder, T. J., Christensen, S., Lindberg, S., Langgård, M., David, L., Maltas, P. J., Eskildsen, J., Jacobsen, J., Tagmose, L., Simonsen, K. B., Biilmann Rønn, L. C., de Jong, I. E. M., Malik, I. J., Karlsson, J.-J., Bundgaard, C., Egebjerg, J., Stavenhagen, J. B., Strandbygård, D., Thirup, S. S. & Andersen, J. L. & 6 others, , 1 Jan 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 1, p. 177-180 4 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review