Research output per year
Research output per year
Personal profile
Research
Ditlev E. Brodersen researches the mechanisms that enable microorganisms, especially bacteria, to survive and resist challenges such as antibiotics and viruses in their environments. Using structural biology, biochemistry, and microbiology, this work aims to gain a deep understanding of these processes. This knowledge can be applied to develop new treatments for infectious diseases.
Teaching
Ditlev E. Brodersen teaches Biomolecular Structure and Function, Immunology and Microbiology, and Introduction to Molecular Biology.
Education/Academic qualification
Chemistry Biotechnology, PhD, Understanding the Structure and Regulation of the S100-Proteins - Recent Advances In Heavy Atom Phasing Methodology
1 Sept 1991 → 31 Aug 1999
Award Date: 13 Jan 2000
External positions
Visiting Professor, University of Parma
1 Nov 2017 → 31 Oct 2020
Keywords
- Microbial processes and substance cycles
- Survival mechanisms
- Bacteria
- Stringent reponse
- Robots
- Automated crystallisation screening
- Structural Analysis
- Visualisation and comparison of protein structures
- 3D structures of large molecules
- Enzymes and artificial enzymes
- RNA
- X-ray crystallography
- Nanoscience and nanotechnology
- Single particle electron microscopy
- Electronic teaching aids
- Teaching goals and methods
Areas of expertise
- Molecular microbiology
- Structural biology
- Protein biochemistry
- Bacterial survival mechanisms
Fingerprint
Dive into the research topics where Ditlev E. Brodersen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein
Manav, M. C., Van, L. B., Lin, J., Fuglsang, A., Peng, X. & Brodersen, D. E., Nov 2020, In: Nature Communications. 11, 1, 10 p., 5993.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System
Bertelsen, M. B., Senissar, M., Nielsen, M. H., Bisiak, F., Cunha, M. V., Molinaro, A. L., Daines, D. A. & Brodersen, D. E., Feb 2021, In: Structure. 29, 2, p. 139-150.e3Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD+
Skjerning, R. B., Senissar, M., Winther, K. S., Gerdes, K. & Brodersen, D. E., Jan 2019, In: Molecular Microbiology. 111, 1, p. 221-236 16 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile154 Downloads (Pure) -
Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology
Harms, A., Brodersen, D. E., Mitarai, N. & Gerdes, K., 7 Jun 2018, In: Molecular Cell. 70, 5, p. 768-784 17 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Open Access -
Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity
He, F., Bhoobalan-Chitty, Y., Van, L. B., Kjeldsen, A. L., Dedola, M., Makarova, K. S., Koonin, E. V., Brodersen, D. E. & Peng, X., Apr 2018, In: Nature Microbiology. 3, 4, p. 461-469 9 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile357 Downloads (Pure)
Activities
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Understanding the molecular mechanism of phosphonate breakdown in bacteria
Brodersen, D. E. (Lecturer)
19 Oct 2023Activity: Talk or presentation types › Lecture and oral contribution
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Using cryo-EM to decipher mechanism and structural rearrangements in a bacterial mega-enzyme
Brodersen, D. E. (Lecturer)
9 Feb 2023Activity: Talk or presentation types › Lecture and oral contribution
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Danmarks Mikrobiologiske Selskab (External organisation)
Brodersen, D. E. (Member)
12 Mar 2024 → …Activity: Membership types › Member of board or management
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Danish Folkschool/Private school/Free school (External organisation)
Brodersen, D. E. (Member)
1 Dec 2023 → …Activity: Membership types › Member of board or management
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Roskilde University
Brodersen, D. E. (Visiting researcher)
10 Nov 2023Activity: Visiting an external institution types › Visiting an external academic institution
Prizes
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ST Education Award 2017
Brodersen, D. E. (Recipient), 25 Aug 2017
Prize: Prizes, scholarships, distinctions
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Hallas Møller Ascending Investigator Grant
Brodersen, D. E. (Recipient), Apr 2018
Prize: Prizes, scholarships, distinctions
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Senior Research Grant 2002
Brodersen, D. E. (Recipient), 1 Oct 2003
Prize: Prizes, scholarships, distinctions
Press/Media
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Ditlev Brodersen awarded prestigious visiting professorship at Università di Parma
05/04/2017
1 Media contribution
Press/Media: Press / Media
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Novel learning platform developed at MBG
11/06/2014
1 item of Media coverage
Press/Media: Press / Media
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Danish researchers reveal how the MRSA bacterium handles stress
15/01/2018
1 Media contribution
Press/Media: Press / Media
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Researchers reveal the secret code language of bacteria
21/12/2016
1 Media contribution
Press/Media: Press / Media
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