David Olagnier

2025

Dual faces of itaconate and its derivatives: exploring diverse biological functions in immunity and infectious diseases

Poulsen, C., Roy, D. G. & Olagnier, D., 26 Mar 2025, (E-pub / Early view) In: Human Molecular Genetics.

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2024

HSP60 controls mitochondrial ATP generation for optimal virus-specific IL-21-producing CD4 and cytotoxic CD8 memory T cell responses

Ghahari, N., Shegefti, S., Alaei, M., Amara, A., Telittchenko, R., Isnard, S., Routy, J.-P., Olagnier, D. & van Grevenynghe, J., 21 Dec 2024, In: Communications Biology. 7, 1, p. 1688 1688.

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Large-scale deep learning identifies the antiviral potential of PKI-179 and MTI-31 against coronaviruses

van der Horst, D., Carter-Timofte, M. E., Danneels, A., Silva da Costa, L., Kurmasheva, N., Thielke, A. L., Hansen, A. L., Chorošajev, V., Holm, C. K., Belouzard, S., de Weber, I., Beny, C. & Olagnier, D., Nov 2024, In: Antiviral Research. 231, 106012.

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2 Citations (Scopus)

Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

Kurmasheva, N., Said, A., Wong, B., Kinderman, P., Han, X., Rahimic, A. H. F., Kress, A., Carter-Timofte, M. E., Holm, E., van der Horst, D., Kollmann, C. F., Liu, Z., Wang, C., Hoang, H.-D., Kovalenko, E., Chrysopoulou, M., Twayana, K. S., Ottosen, R. N., Svenningsen, E. B. & Begnini, F. & 30 others, Kiib, A. E., Kromm, F. E. H., Weiss, H. J., Di Carlo, D., Muscolini, M., Higgins, M., van der Heijden, M., Bardoul, A., Tong, T., Ozsvar, A., Hou, W.-H., Schack, V. R., Holm, C. K., Zheng, Y., Ruzek, M., Kalucka, J., de la Vega, L., Elgaher, W. A. M., Korshoej, A. R., Lin, R., Hiscott, J., Poulsen, T., O'Neill, L. A., Roy, D. G., Rinschen, M. M., van Montfoort, N., Diallo, J.-S., Farin, H. F., Alain, T. & Olagnier, D., May 2024, In: Nature Communications. 15, 1, 28 p., 4096.

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7 Citations (Scopus)

SAM68 directs STING signaling to apoptosis in macrophages

van der Horst, D., Kurmasheva, N., Marqvorsen, M. H. S., Assil, S., Rahimic, A. H. F., Kollmann, C. F., Silva da Costa, L., Wu, Q., Zhao, J., Cesari, E., Iversen, M. B., Ren, F., Jensen, T. I., Narita, R., Schack, V. R., Zhang, B.-C., Bak, R. O., Sette, C., Fenton, R. A. & Mikkelsen, J. G. & 2 others, Paludan, S. R. & Olagnier, D., Mar 2024, In: Communications Biology. 7, p. 283 283.

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2 Citations (Scopus)

Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors

Qin, Y., Poulsen, C., Narayanan, D., Chan, C. B., Chen, X., Montes, B. R., Tran, K. T., Mukminova, E., Lin, C., Gajhede, M., Bullock, A. N., Olagnier, D. & Bach, A., 14 Nov 2024, In: Journal of Medicinal Chemistry. 67, 21, p. 18828-18864 37 p.

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4 Citations (Scopus)

The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation

Farahani, E., Reinert, L. S., Narita, R., Serrero, M. C., Skouboe, M. K., van der Horst, D., Assil, S., Zhang, B., Iversen, M. B., Gutierrez, E., Hazrati, H., Johannsen, M., Olagnier, D., Kunze, R., Denham, M., Mogensen, T. H., Lappe, M. & Paludan, S. R., 27 Feb 2024, In: Cell Reports. 43, 2, p. 113792 113792.

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4 Citations (Scopus)

2023

Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1

Hoang, H.-D., Said, A., Vaidya, N., Gilchrist, V. H., Malone, K., Kabilan, U., Topshee, S., Xiang, X., Yang, A.-D., Olagnier, D., Mossman, K., Beug, S. T., Jafarnejad, S. M., Workenhe, S. T., Graber, T. E. & Alain, T., 23 Mar 2023, In: Journal for Immunotherapy of Cancer. 11, 3, 23 p., e006408.

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2 Citations (Scopus)

Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development

Boulton, S., Crupi, M. J. F., Singh, S., Carter-Timofte, M. E., Azad, T., Organ, B. C., He, X., Gill, R., Neault, S., Jamieson, T., Dave, J., Kurmasheva, N., Austin, B., Petryk, J., Singaravelu, R., Huang, B. Z., Franco, N., Babu, K., Parks, R. J. & Ilkow, C. S. & 2 others, Olagnier, D. & Bell, J. C., Jun 2023, In: The Journal of Biological Chemistry. 299, 6, 104749.

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NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

Waqas, F. H., Shehata, M., Elgaher, W. A. M., Lacour, A., Kurmasheva, N., Begnini, F., Kiib, A. E., Dahlmann, J., Chen, C., Pavlou, A., Poulsen, T. B., Merkert, S., Martin, U., Olmer, R., Olagnier, D., Hirsch, A. K. H., Pleschka, S. & Pessler, F., Jul 2023, In: PLOS Pathogens. 19, 7, 24 p., e1011506.

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24 Citations (Scopus)

The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2

Vierbuchen, T., Agarwal, S., Johnson, J. L., Galia, L., Lei, X., Stein, K., Olagnier, D., Gaede, K. I., Herzmann, C., Holm, C. K., Heine, H., Pai, A., O'Hara Hall, A., Hoebe, K. & Fitzgerald, K. A., Jan 2023, In: Proceedings of the National Academy of Sciences (PNAS). 120, 1, 10 p., e2213715120.

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29 Citations (Scopus)

3 Downloads (Pure)

2022

Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells

Loucif, H., Dagenais-Lussier, X., Avizonis, D., Choinière, L., Beji, C., Cassin, L., Routy, J.-P., Fritz, J. H., Olagnier, D. & van Grevenynghe, J., Jun 2022, In: Autophagy. 18, 6, p. 1256-1273 18 p.

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15 Citations (Scopus)

Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery

Narayanan, D., Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Qin, Y., Mukminova, E., Luchini, M., Vasilyeva, K. O., González Chichón, D., Goutsiou, G., Poulsen, C., Haapanen, N., Popowicz, G. M., Sattler, M., Olagnier, D., Gajhede, M. & Bach, A., Nov 2022, In: Journal of Medicinal Chemistry. 65, 21, p. 14481–14526 46 p.

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29 Citations (Scopus)

Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen

Taha, Z., Arulanandam, R., Maznyi, G., Godbout, E., Carter-Timofte, M. E., Kurmasheva, N., Reinert, L. S., Chen, A., Crupi, M. J. F., Boulton, S., Laroche, G., Phan, A., Rezaei, R., Alluqmani, N., Jirovec, A., Acal, A., Brown, E. E. F., Singaravelu, R., Petryk, J. & Idorn, M. & 13 others, Potts, K. G., Todesco, H., John, C., Mahoney, D. J., Ilkow, C. S., Giguère, P., Alain, T., Côté, M., Paludan, S. R., Olagnier, D., Bell, J. C., Azad, T. & Diallo, J.-S., Sept 2022, In: Molecular Therapy. 30, 9, p. 2998-3016 19 p.

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7 Citations (Scopus)

Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I-Mediated Antiviral Responses in Primary Human Dendritic Cells

Zevini, A., Palermo, E., Di Carlo, D., Alexandridi, M., Rinaldo, S., Paone, A., Cutruzzola, F., Etna, M. P., Coccia, E. M., Olagnier, D. & Hiscott, J., Jul 2022, In: Frontiers in cellular and infection microbiology. 12, 14 p., 910864.

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6 Citations (Scopus)

Postpartum Disseminated Herpes Simplex Virus Type 1 Infection With Hemophagocytic Lymphohistiocytosis and Fulminant Neonatal Herpes Infection

Freytag, M. R., Jørgensen, S. E., Thomsen, M. M., Al-Mousawi, A., Hait, A. S., Olagnier, D., Bay, J. T., Helleberg, M. & Mogensen, T. H., 1 Jan 2022, In: The Journal of Infectious Diseases. 225, 1, p. 157-162 6 p.

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5 Citations (Scopus)

The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity

Casares, L., Moreno, R., Ali, K. X., Higgins, M., Dayalan Naidu, S., Neill, G., Cassin, L., Kiib, A. E., Svenningsen, E. B., Minassi, A., Honda, T., Poulsen, T. B., Wiel, C., Sayin, V. I., Dinkova-Kostova, A. T., Olagnier, D. & de la Vega, L., May 2022, In: Redox Biology. 51, 11 p., 102291.

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17 Citations (Scopus)

TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection

van der Sluis, R. M., Cham, L. B., Gris-Oliver, A., Gammelgaard, K. R., Pedersen, J. G., Idorn, M., Ahmadov, U., Hernandez, S. S., Cémalovic, E., Godsk, S. H., Thyrsted, J., Gunst, J. D., Nielsen, S. D., Jørgensen, J. J., Bjerg, T. W., Laustsen, A., Reinert, L. S., Olagnier, D., Bak, R. O. & Kjolby, M. & 6 others, Holm, C. K., Tolstrup, M., Paludan, S. R., Kristensen, L. S., Søgaard, O. S. & Jakobsen, M. R., May 2022, In: EMBO Journal. 41, 10, 19 p., e109622.

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64 Citations (Scopus)

55 Downloads (Pure)

VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney

Rinschen, M. M., Harder, J. L., Carter-Timofte, M. E., Zanon Rodriguez, L., Mirabelli, C., Demir, F., Kurmasheva, N., Ramakrishnan, S. K., Kunke, M., Tan, Y., Billing, A., Dahlke, E., Larionov, A. A., Bechtel-Walz, W., Aukschun, U., Grabbe, M., Nielsen, R., Christensen, E. I., Kretzler, M. & Huber, T. B. & 5 others, Wobus, C. E., Olagnier, D., Siuzdak, G., Grahammer, F. & Theilig, F., 29 Nov 2022, In: Science Signaling. 15, 762, p. eabo7940 eabo7940.

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15 Citations (Scopus)

2021

Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern

Carter-Timofte, M. E., Arulanandam, R., Kurmasheva, N., Fu, K., Laroche, G., Taha, Z., Van Der Horst, D., Cassin, L., Van Der Sluis, R. M., Palermo, E., Di Carlo, D., Jacobs, D., Maznyi, G., Azad, T., Singaravelu, R., Ren, F., Hansen, A. L., Idorn, M., Holm, C. K. & Jakobsen, M. R. & 10 others, Van Grevenynghe, J., Hiscott, J., Paludan, S. R., Bell, J. C., Seguin, J., Sabourin, L. A., Côté, M., Diallo, J. S., Alain, T. & Olagnier, D., 12 Nov 2021, In: ACS Infectious Diseases. 7, 11, p. 3034-3051 18 p.

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18 Citations (Scopus)

Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

Hait, A. S., Olagnier, D., Sancho-Shimizu, V., Skipper, K. A., Helleberg, M., Larsen, S. M., Bodda, C., Moldovan, L. I., Ren, F., Brinck Andersen, N.-S., Thomsen, M. M., Freytag, M. R., Darmalinggam, S., Parkes, I., Kadekar, D. D., Rahbek, S. H., van der Horst, D., Kristensen, L. S., Eriksson, K. & Kjems, J. & 6 others, Mostowy, S., Christiansen, M., Mikkelsen, J. G., Brandt, C. T., Paludan, S. R. & Mogensen, T. H., 23 Dec 2021, In: Science Immunology. 5, 54, 17 p., eabc2691.

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35 Citations (Scopus)

Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium

Thyrsted, J., Storgaard, J., Blay-Cadanet, J., Heinz, A., Thielke, A. L., Crotta, S., de Paoli, F., Olagnier, D., Wack, A., Hiller, K., Hansen, A. L. & Holm, C. K., 19 Nov 2021, In: iScience. 24, 11, p. 103300 103300.

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17 Citations (Scopus)

Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro

Svenningsen, E. B., Thyrsted, J., Blay-Cadanet, J., Liu, H., Lin, S., Villameriel, J. M., Olagnier, D., Idorn, M., Paludan, S. R., Holm, C. K. & Poulsen, T. B., Jan 2021, In: Antiviral Research. 185, 5 p., 104988.

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19 Citations (Scopus)

Lipophagy confers a key metabolic advantage that ensures protective CD8A T-cell responses against HIV-1

Loucif, H., Dagenais-Lussier, X., Beji, C., Cassin, L., Jrade, H., Tellitchenko, R., Routy, J.-P., Olagnier, D. & van Grevenynghe, J., Nov 2021, In: Autophagy. 17, 11, p. 3408-3423 16 p.

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15 Citations (Scopus)

2020

Dengue virus infection and Nrf2 regulation of oxidative stress

Zevini, A., Ferrari, M., Olagnier, D. & Hiscott, J., Aug 2020, In: Current Opinion in HIV and AIDS. 43, p. 35-40 6 p.

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14 Citations (Scopus)

Dengue virus targets Nrf2 for NS2B3-mediated degradation leading to enhanced oxidative stress and viral replication

Ferrari, M., Zevini, A., Palermo, E., Muscolini, M., Alexandridi, M., Etna, M. P., Coccia, E. M., Fernandez-Sesma, A., Coyne, C., Zhang, D., Marques, E. T. A., Olagnier, D. & Hiscott, J., Dec 2020, In: Journal of Virology. 94, 24, 21 p., e01551.

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48 Citations (Scopus)

SARS-CoV-2 evades immune detection in alveolar macrophages

Dalskov, L., Møhlenberg, M., Thyrsted, J., Blay-Cadanet, J., Poulsen, E. T., Folkersen, B. H., Skaarup, S. H., Olagnier, D., Reinert, L., Enghild, J. J., Hoffmann, H. J., Holm, C. K. & Hartmann, R., Dec 2020, In: EMBO Reports. 21, 12, e51252.

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58 Citations (Scopus)

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

Olagnier, D., Farahani, E., Thyrsted, J., Blay-Cadanet, J., Herengt, A., Idorn, M., Hait, A., Hernaez, B., Knudsen, A., Iversen, M. B., Schilling, M., Jørgensen, S. E., Thomsen, M., Reinert, L. S., Lappe, M., Hoang, H.-D., Gilchrist, V. H., Hansen, A. L., Ottosen, R. & Nielsen, C. G. & 18 others, Møller, C., van der Horst, D., Peri, S., Balachandran, S., Huang, J., Jakobsen, M., Svenningsen, E. B., Poulsen, T. B., Bartsch, L., Thielke, A. L., Luo, Y., Alain, T., Rehwinkel, J., Alcamí, A., Hiscott, J., Mogensen, T. H., Paludan, S. R. & Holm, C. K., 1 Dec 2020, In: Nature Communications. 11, 1, 12 p., 4938.

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320 Citations (Scopus)

STEEP mediates STING ER exit and activation of signaling

Zhang, B. C., Nandakumar, R., Reinert, L. S., Huang, J., Laustsen, A., Gao, Z. L., Sun, C. L., Jensen, S. B., Troldborg, A., Assil, S., Berthelsen, M. F., Scavenius, C., Zhang, Y., Windross, S. J., Olagnier, D., Prabakaran, T., Bodda, C., Narita, R., Cai, Y. & Zhang, C. G. & 11 others, Stenmark, H., Doucet, C. M., Noda, T., Guo, Z., Goldbach-Mansky, R., Hartmann, R., Chen, Z. J., Enghild, J. J., Bak, R. O., Thomsen, M. K. & Paludan, S. R., 2020, In: Nature Immunology. 21, 8, p. 868-879 12 p.

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115 Citations (Scopus)

The Covid-19 pandemic in Denmark: Big lessons from a small country

Olagnier, D. & Mogensen, T. H., Jun 2020, In: Cytokine & Growth Factor Reviews. 53, p. 10-12 3 p.

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76 Citations (Scopus)

2019

An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation

Castiello, L., Zevini, A., Vulpis, E., Muscolini, M., Ferrari, M., Palermo, E., Peruzzi, G., Krapp, C., Jakobsen, M., Olagnier, D., Zingoni, A., Santoni, A. & Hiscott, J., 2019, In: Cancer Immunology, Immunotherapy. 68, 9, p. 1479-1492 14 p.

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25 Citations (Scopus)

Changes in monocyte subsets are associated with clinical outcomes in severe malarial anaemia and cerebral malaria

Royo, J., Rahabi, M., Kamaliddin, C., Ezinmegnon, S., Olagnier, D., Authier, H., Massougbodji, A., Alao, J., Ladipo, Y., Deloron, P., Bertin, G., Pipy, B., Coste, A. & Aubouy, A., 2019, In: Scientific Reports. 9, 1, 13 p., 17545.

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20 Citations (Scopus)

Nrf2 Negatively Regulates Type I Interferon Responses and Increases Susceptibility to Herpes Genital Infection in Mice

Gunderstofte, C., Iversen, M. B., Peri, S., Thielke, A., Balachandran, S., Holm, C. K. & Olagnier, D., Sept 2019, In: Frontiers in Immunology. 10, 11 p., 2101.

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24 Citations (Scopus)

SIRT1 modulates the sensitivity of prostate cancer cells to vesicular stomatitis virus oncolysis

Muscolini, M., Castiello, L., Palermo, E., Zevini, A., Ferrari, M., Olagnier, D. & Hiscott, J., Aug 2019, In: Journal of Virology. 93, 14 p., e00626-19.

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19 Citations (Scopus)

2018

Global transcriptional changes in response to cGAMP depend on STING in human THP-1 cells

Hansen, A. L., Brandtoft, A. M., Nyegaard, M., Thielke, A. L., Olagnier, D. & Holm, C. K., 1 Nov 2018, In: Cellular & molecular immunology. 15, 11, p. 983-985 3 p.

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4 Citations (Scopus)

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

Hansen, A. L., Buchan, G. J., Rühl, M., Mukai, K., Salvatore, S. R., Ogawa, E., Andersen, S. D., Iversen, M. B., Thielke, A. L., Gunderstofte, C., Motwani, M., Møller, C. T., Jakobsen, A. S., Fitzgerald, K. A., Roos, J., Lin, R., Maier, T. J., Goldbach-Mansky, R., Miner, C. A. & Qian, W. & 9 others, Miner, J. J., Rigby, R. E., Rehwinkel, J., Jakobsen, M. R., Arai, H., Taguchi, T., Schopfer, F. J., Olagnier, D. & Holm, C. K., 14 Aug 2018, In: Proceedings of the National Academy of Sciences (PNAS). 115, 33, p. E7768-E7775 8 p.

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204 Citations (Scopus)

121 Downloads (Pure)

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

Olagnier, D., Brandtoft, A. M., Gunderstofte, C., Villadsen, N. L., Krapp, C., Thielke, A. L., Laustsen, A., Peri, S., Hansen, A. L., Bonefeld, L., Thyrsted, J., Bruun, V., Iversen, M. B., Lin, L., Artegoitia, V. M., Su, C., Yang, L., Lin, R., Balachandran, S. & Luo, Y. & 14 others, Nyegaard, M., Marrero, B., Goldbach-Mansky, R., Motwani, M., Ryan, D. G., Fitzgerald, K. A., O'Neill, L. A., Hollensen, A. K., Damgaard, C. K., de Paoli, F. V., Bertram, H. C., Jakobsen, M. R., Poulsen, T. B. & Holm, C. K., 1 Dec 2018, In: Nature Communications. 9, 1, 13 p., 3506.

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210 Citations (Scopus)

2017

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

Olagnier, D., Lababidi, R. R., Hadj, S. B., Sze, A., Liu, Y., Naidu, S. D., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M.-L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R., 2 Aug 2017, In: Molecular Therapy. 25, 8, p. 1900-1916 17 p.

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71 Citations (Scopus)

Evaluation of Innate Immune Gene Expression Following HDAC Inhibitor Treatment by High Throughput qPCR and PhosFlow Cytometry

Olagnier, D., Chiang, C. & Hiscott, J., 2017, In: Methods in molecular biology (Clifton, N.J.). 1510, p. 245-255 11 p.

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1 Citation (Scopus)

RIGulation of STING expression: at the crossroads of viral RNA and DNA sensing pathways

Liu, Y., Lin, R. & Olagnier, D., 1 Jan 2017, In: Inflammation and cell signaling. 4, 1, p. e1491

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Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference

Sze, A., Olagnier, D., Hadj, S. B., Han, X., Tian, X. H., Xu, H.-T., Yang, L., Shi, Q., Wang, P., Wainberg, M. A., Wu, J. H. & Lin, R., 3 Oct 2017, In: Viruses. 9, 10, 287.

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14 Citations (Scopus)

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

Dayalan Naidu, S., Dikovskaya, D., Gaurilcikaite, E., Knatko, E. V., Healy, Z. R., Mohan, H., Koh, G., Laurell, A., Ball, G., Olagnier, D., de la Vega, L., Ganley, I. G., Talalay, P. & Dinkova-Kostova, A. T., 1 Dec 2017, In: Scientific Reports. 7, 1, 11023.

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35 Citations (Scopus)

2016

Mechanisms of Zika Virus Infection and Neuropathogenesis

Olagnier, D., Muscolini, M., Coyne, C. B., Diamond, M. S. & Hiscott, J., Aug 2016, In: D N A and Cell Biology. 35, 8, p. 367-72 6 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

46 Citations (Scopus)

RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection

Liu, Y., Goulet, M.-L., Sze, A., Hadj, S. B., Belgnaoui, S. M., Lababidi, R. R., Zheng, C., Fritz, J. H., Olagnier, D. & Lin, R., 15 Oct 2016, In: Journal of Virology. 90, 20, p. 9406-19 14 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

71 Citations (Scopus)

2015

Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

Beljanski, V., Chiang, C., Kirchenbaum, G. A., Olagnier, D., Bloom, C. E., Wong, T., Haddad, E. K., Trautmann, L., Ross, T. M. & Hiscott, J., Oct 2015, In: Journal of Virology. 89, 20, p. 10612-24 13 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

59 Citations (Scopus)

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

Metcalf, T. U., Cubas, R. A., Ghneim, K., Cartwright, M. J., Grevenynghe, J. V., Richner, J. M., Olagnier, D. P., Wilkinson, P. A., Cameron, M. J., Park, B. S., Hiscott, J. B., Diamond, M. S., Wertheimer, A. M., Nikolich-Zugich, J. & Haddad, E. K., Jun 2015, In: Aging Cell. 14, 3, p. 421-32 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

147 Citations (Scopus)

Nrf2-driven CD36 and HO-1 gene expression in circulating monocytes correlates with favourable clinical outcome in pregnancy-associated malaria

Aubouy, A., Olagnier, D., Bertin, G., Ezinmegnon, S., Majorel, C., Mimar, S., Massougbodji, A., Deloron, P., Pipy, B. & Coste, A., 18 Sept 2015, In: Malaria Journal. 14, p. 358

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21 Citations (Scopus)

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists

Chiang, C., Beljanski, V., Yin, K., Olagnier, D., Ben Yebdri, F., Steel, C., Goulet, M.-L., DeFilippis, V. R., Streblow, D. N., Haddad, E. K., Trautmann, L., Ross, T., Lin, R. & Hiscott, J., Aug 2015, In: Journal of Virology. 89, 15, p. 8011-25 15 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

81 Citations (Scopus)

2014

Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells

Olagnier, D., Peri, S., Steel, C., van Montfoort, N., Chiang, C., Beljanski, V., Slifker, M., He, Z., Nichols, C. N., Lin, R., Balachandran, S. & Hiscott, J., Dec 2014, In: P L o S Pathogens. 10, 12, p. e1004566

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

199 Citations (Scopus)

Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation

Feng, Q., Langereis, M. A., Olagnier, D., Chiang, C., van de Winkel, R., van Essen, P., Zoll, J., Hiscott, J. & van Kuppeveld, F. J. M., 2014, In: P L o S One. 9, 4, p. e95927

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19 Citations (Scopus)

David Olagnier

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