Daniel Otzen

  1. Journal article
  2. Published

    Stop-and-go kinetics in amyloid fibrillation. / Ferkinghoff-Borg, Jesper; Fonslet, Jesper; Andersen, Christian Beyschau; Krishna, Sandeep; Pigolotti, Simone; Yagi, Hisashi; Goto, Yuji; Otzen, Daniel; Jensen, Mogens H.

    In: Physical Review E. Statistical, Nonlinear, and Soft Matter Physics, Vol. 82, No. 1 Pt 1, 01.07.2010, p. 010901.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential. / Ferreira, Nelson; Gram, Hjalte; Sorrentino, Zachary A; Gregersen, Emil; Schmidt, Sissel Ida; Reimer, Lasse; Betzer, Cristine; Perez-Gozalbo, Clara; Beltoja, Marjo; Nagaraj, Madhu; Wang, Jie; Nowak, Jan S; Dong, Mingdong; Willén, Katarina; Cholak, Ersoy; Bjerregaard-Andersen, Kaare; Mendez, Nicolas; Rabadia, Prakruti; Shahnawaz, Mohammad; Soto, Claudio; Otzen, Daniel E; Meyer, Morten; Giasson, Benoit I; Romero-Ramos, Marina; Jensen, Poul Henning.

    In: Acta Neuropathologica, Vol. 142, 07.2021, p. 87-115.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Single versus parallel pathways of protein folding and fractional formation of structure in the transition state. / Fersht, Alan R.; Itzhaki, Laura S.; Elmasry, Nadia F.; Matthews, Jacqueline M.; Otzen, Daniel E.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 22, 25.10.1994, p. 10426-10429.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    The natural, peptaibolic peptide SPF-5506-A4 adopts a β-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores. / Frahm, Heidi; Hansen, Sara K; Vad, Brian S; Nielsen, Erik H; Nielsen, Jakob T; Vosegaard, Thomas; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 8, 08.2015, p. 882-889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Quantitative use of paramagnetic relaxation enhancements for determining orientation and insertion depth of peptides in micelles. / Franzmann, Magnus; Otzen, Daniel; Wimmer, Reinhard.

    In: ChemBioChem, Vol. 10, 2009, p. 2339-2347.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Dynamic content exchange between liprotides. / Frislev, Henriette S; Jakobsen, Stine C L; Frank, Signe A; Otzen, Daniel E.

    In: Biophysical Chemistry, Vol. 233, 02.2018, p. 13-18.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Liprotides kill cancer cells by disrupting the plasma membrane. / Frislev, Henriette S; Boye, Theresa Louise; Nylandsted, Jesper; Otzen, Daniel.

    In: Scientific Reports, Vol. 7, 15129, 09.11.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Liprotides made of α-lactalbumin and cis fatty acids form core-shell and multi-layer structures with a common membrane-targeting mechanism. / Frislev, Henriette Kristina Søster; Jessen, Christian M; Oliveira, Cristiano L P; Pedersen, Jan Skov; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1864, No. 7, 2016, p. 847-859.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Using Liprotides to Deliver Cholesterol to the Plasma Membrane. / Frislev, Henriette S.; Nielsen, Janni; Nylandsted, Jesper; Otzen, Daniel.

    In: Journal of Membrane Biology, Vol. 25, No. 4, 08.2018, p. 581-592.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Protein drug stability: a formulation challenge. / Frøkjær, Sven; Otzen, Daniel.

    In: Nature Reviews. Drug Discovery, Vol. 4, 2005, p. 298-306.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Mapping out the multistage fibrillation of glucagon. / Ghodke, Shirin; Nielsen, Søren B; Christiansen, Gunna; Hjuler, Hans Aage; Flink, James; Otzen, Daniel; Nielsen, Søren Bang.

    In: F E B S Journal, Vol. 279, No. 5, 03.2012, p. 752-765.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    An Aß concatemer with altered aggregation propensities. / Giehm, L; Dal Degan, F; Fraser, P; Klysner, S; Otzen, Daniel E.

    In: BBA General Subjects, Vol. 1804, No. 10, 01.10.2010, p. 2025-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Assays for alpha-synuclein aggregation. / Giehm, Lise; Lorenzen, Nikolai; Otzen, Daniel.

    In: Methods, Vol. 53, No. 3, 2011, p. 295-305.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Assays for α-synuclein aggregation. / Giehm, Lise; Lorenzen, Nikolai; Otzen, Daniel E.

    In: Methods, 14.12.2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Dendrimers destabilize proteins in a generation-dependent manner involving eletrostatic interactions. / Giehm, Lise; Christensen, C.; Boas, U.; Heegaard, P. M. H.; Otzen, Daniel.

    In: Biopolymers, Vol. 89, 2008, p. 522-529.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation. / Giehm, Lise; Svergun, Dmitri I; Otzen, Daniel E; Vestergaard, Bente.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 8, 22.02.2011, p. 3246-3251.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    SDS-Induced Fibrillation of α-Synuclein: An Alternative Fibrillation Pathway. / Giehm, Lise; Oliveira, Cristiano Luis Pinto De; Christiansen, Gunna; Pedersen, Jan Skov; Otzen, Daniel.

    In: Journal of Molecular Biology, Vol. 401, 2010, p. 115-133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Strategies to increase the reproducibility of protein fibrillization in plate reader assays. / Giehm, Lise; Otzen, Daniel E.

    In: Analytical Biochemistry, Vol. 400, No. 2, 15.05.2010, p. 270-81.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Strategies to increase the reproducibility of α-synuclein fibrillation in plate reader assays. / Giehm, Lise; Otzen, Daniel.

    In: Analytical Biochemistry, Vol. 406, No. 2, 15.11.2010, p. 270-281.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    An unusual intrinsically disordered protein from the model legume Lotus japonicus stabilizes proteins in vitro. / Haaning, Svend; Radutoiu, Simona; Hoffmann, Søren V; Dittmer, Jens; Giehm, Lise; Otzen, Daniel; Stougaard, Jens.

    In: Journal of Biological Chemistry, Vol. 283, No. 45, 2008, p. 31142-52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    The bacterial amyloids phenol soluble modulins from staphylococcus aureus catalyze alpha-synuclein aggregation. / Haikal, Caroline; Pascual, Lei Ortigosa; Najarzadeh, Zahra; Bernfur, Katja; Svanbergsson, Alexander; Otzen, Daniel E.; Linse, Sara; Li, Jia Yi.

    In: International Journal of Molecular Sciences, Vol. 22, No. 21, 11594, 11.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Amyloid fibril inhibition, acceleration, or fragmentation : Are nano-based approaches advance in the right direction? / Hajipour, Mohammad Javad; Mohammad-Beigi, Hossein; Nabipour, Iraj; Mahmoudi, Negar; Azhdarzadeh, Morteza; Derakhshankhah, Hossein; El Dawud, Dina; Mohammadinejad, Reza; Otzen, Daniel.

    In: Nano Today, Vol. 35, No. December, 100983, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Stable intermediates determine proteins' primary unfolding sites in the presence of surfactants. / Hansen, Jonas Høeg; Petersen, Steen Vang; Andersen, Kell Kleiner; Enghild, Jan J; Damhus, Ture; Otzen, Daniel.

    In: Biopolymers, Vol. 91, No. 3, 2009, p. 221-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Effect of protein-surfactant interactions on aggregation of β-lactoglobulin. / Hansted, Jon Gade; Wejse, Peter L; Bertelsen, Hans; Otzen, Daniel E.

    In: BBA General Subjects, Vol. 1814, No. 5, 2011, p. 713-723.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin. / He, Jianfei; Becares, Eva Ramos; Thulstrup, Peter Waaben; Gamon, Luke F.; Pedersen, Jannik Nedergaard; Otzen, Daniel; Gourdon, Pontus; Davies, Michael J.; Hägglund, Per.

    In: Redox Biology, Vol. 36, 101631, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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