Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. Journal article
  2. Published

    The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage. / Christiansen, Stig Hill; Zhang, Xianwei; Juul-Madsen, Kristian; Hvam, Michael Lykke; Vad, Brian Stougaard; Behrens, Manja Annette; Thygesen, Ida Lysgaard; Jalilian, Babak; Pedersen, Jan Skov; Howard, Ken; Otzen, Daniel E; Vorup-Jensen, Thomas.

    In: B B A - Biomembranes, Vol. 1859, No. 3, 03.2017, p. 425-437.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology. / Christiansen, Josefine R; Olesen, Mads N; Otzen, Daniel E; Romero-Ramos, Marina; Sanchez-Guajardo, Vanesa.

    In: Journal of Neuroinflammation, Vol. 13, 74, 09.04.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Scaffolded multimers of hIAPP20-29 peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP20-29 peptide fragment. / Christoffersen, Heidi F; Andreasen, Maria; Zhang, Shuai; Nielsen, Erik Holm; Christiansen, Gunna; Dong, Mingdong; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 12, 12.2015, p. 1890-1897.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Enzymatic characterisation of novamyl®, a thermostable α-amylase. / Christophersen, Claus; Otzen, Daniel E.; Norman, Barrie E.; Christensen, Søren; Schäfer, Thomas.

    In: Starch/Staerke, Vol. 50, No. 1, 01.01.1998, p. 39-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. / Cohen, Samuel I A; Linse, Sara; Luheshi, Leila M; Hellstrand, Erik; White, Duncan A; Rajah, Luke; Otzen, Daniel; Vendruscolo, Michele; Dobson, Christopher M; Knowles, Tuomas P J.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 24, 23.05.2013, p. 9758-9763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Structure of the transition state for folding of a protein derived from experiment and simulation. / Daggett, Valerie; Li, Aijun; Itzhaki, Laura S.; Otzen, Daniel E.; Fersht, Alan R.

    In: Journal of Molecular Biology, Vol. 257, No. 2, 29.03.1996, p. 430-440.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Changes in structures of milk proteins upon photo-oxidation. / Dalsgaard, Trine Kastrup; Otzen, Daniel; Nielsen, J. H.; Larsen, L. B.

    In: J. Agr. Food Chem., No. 55, 2007, p. 10968-10976.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Conformational pathway of the polypeptide chain of chymotrypsin inhibitor-2 growing from its N terminus in vitro. Parallels with the protein folding pathway. / De Prat Gay, Gonzalo; Ruiz-Sanz, Javier; Neira, José L.; Corrales, Fernando J.; Otzen, Daniel E.; Ladurner, Andreas G.; Fersht, Alan R.

    In: Journal of Molecular Biology, Vol. 254, No. 5, 15.12.1995, p. 968-979.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Cell-free synthesis and folding of transmembrane OmpA reveals higher order structures and premature truncations. / Debnath, Dilip K; Otzen, Daniel E.

    In: Advances in Biophysical Chemistry, Vol. 152, No. 1-3, 01.11.2010, p. 80-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    In vitro association of fragments of a beta-sheet membrane protein. / Debnath, D; Nielsen, K L; Otzen, D E.

    In: Advances in Biophysical Chemistry, Vol. 148, No. 1-3, 01.05.2010, p. 112-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    The role of membrane properties in Mistic folding and dimerisation. / Debnath, Dilip Kumar; Basaiawmoit, Rajiv Vaid; Nielsen, Kåre Lehmann; Otzen, Daniel E.

    In: Protein Engineering Design and Selection (Print), Vol. 24, No. 1-2, 01.01.2011, p. 89-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Off-pathway aggregation can inhibit fibrillation at high protein concentrations. / Deva, Taru; Lorenzen, Nikolai; Vad, Brian S; Petersen, Steen V; Thørgersen, Ida; Enghild, Jan J; Kristensen, Torsten; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 3, 03.2013, p. 677-687.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon. / Dong, Mingdong; Hovgaard, Mads Bruun; Mamdouh, Wael; Xu, Sailong; Otzen, Daniel; Besenbacher, Flemming.

    In: Nanotechnology, Vol. 19, 2008, p. 384013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon : Nanotechnology. / Dong, M. D.; Hovgaard, M. B.; Mamdouh, W.; Xu, S. L.; Otzen, D. E.; Besenbacher, F.

    In: Nanotechnology, Vol. 19, No. 38, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Membrane Interactions of Novicidin, a Novel Antimicrobial Peptide: Phosphatidylglycerol Promotes Bilayer Insertion. / Dorosz, Jerzy; Gofman, Yana; Kolusheva, Sofiya; Otzen, Daniel; Ben-Tal, Nir; Nielsen, Niels Christian; Jelinek, Raz.

    In: The Journal of Physical Chemistry B, Vol. 114, No. 34, 2010, p. 11053-60.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    1-16 Can Aggregate and induce the Production of Reactive Oxygen Species, Nitric Oxide, and Inflammatory Cytokines. / Du, Xue-ting; Wang, Li; Wang, Yu-jiong; Andreasen, Maria; Zhan, Da-wei; Feng, Ying; Li, Min; Zhao, Min; Otzen, Daniel; Xue, Di; Yang, Yang; Liu, Rui-tian.

    In: Journal of Alzheimer's Disease, Vol. 27, No. 2, 11.2011, p. 401-413.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Curli functional amyloid systems are phylogenetically widespread and display large diversity in operon and protein structure. / Dueholm, Morten S; Albertsen, Mads; Otzen, Daniel; Nielsen, Per Halkjær.

    In: P L o S One, Vol. 7, No. 12, 12.12.2012, p. e51274.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Evolutionary Insight into the Functional Amyloids of the Pseudomonads. / Dueholm, Morten Simonsen; Otzen, Daniel; Nielsen, Per Halkjær.

    In: PLOS ONE, Vol. 8, No. 10, e76630, 07.10.2013, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation. / Dueholm, Morten S; Søndergaard, Mads; Nilsson, Martin; Christiansen, Gunna; Stensballe, Allan; Overgaard, Michael T; Givskov, Michael Christian; Tolker-Nielsen, Tim; Otzen, Daniel; Nielsen, Per H.

    In: MicrobiologyOpen, Vol. 2, No. 3, 06.2013, p. 365-382.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation. / Dueholm, Morten S; Nielsen, Søren Bang; Hein, Kim L; Nissen, Poul; Chapman, Matthew; Christiansen, Gunna; Nielsen, Per Halkjær; Otzen, Daniel E.

    In: Biochemistry, Vol. 50, No. 39, 2011, p. 8281-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Functional amyloid in Pseudomonas. / Dueholm, Morten S; Petersen, Steen V; Sønderkær, Mads; Larsen, Poul; Christiansen, Gunna; Hein, Kim L; Enghild, Jan J; Nielsen, Jeppe L; Nielsen, Kåre L; Nielsen, Per H; Otzen, Daniel E.

    In: Molecular Microbiology, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    The Tubular Sheaths Encasing Methanosaeta thermophila Filaments are Functional Amyloids. / Dueholm, Morten S; Larsen, Poul; Finster, Kai; Stenvang, Marcel R; Christiansen, Gunna; Vad, Brian S; Bøggild, Andreas; Otzen, Daniel E; Halkjær Nielsen, Per.

    In: Journal of Biological Chemistry, Vol. 290, 24.06.2015, p. 20590-26600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Inhibitors of α-Synuclein fibrillation and oligomer toxicity in Rosa damascena : the all-pervading powers of flavonoids and phenolic glycosides. / Eskandari, Hoda; Ghanadian, Mustafa; Noleto-Dias, Clarice; Lomax, Charlotte; Tawfike, Ahmed; Christiansen, Gunna; Sutherland, Duncan S; Ward, Jane L; Mohammad-Beigi, Hossein; Otzen, Daniel Erik.

    In: ACS Chemical Neuroscience, Vol. 11, No. 19, 10.2020, p. 3161–3173.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Sucrose prevents protein fibrillation through compaction of the tertiary structure but hardly affects the secondary structure. / Estrela, Nídia; Franquelim, Henri G; Lopes, Carlos; Tavares, Evandro; Macedo, Joana A; Christiansen, Gunna; Otzen, Daniel E; Melo, Eduardo P.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 83, No. 11, 11.2015, p. 2039-2051.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Properties of PEG-modified microbial proteases. Activity and stability studies. / Fatum, T. M.; Olsen, A. Agerlin; Fuglsang, C. C.; Otzen, D.

    In: Progress in Biotechnology, Vol. 15, No. C, 01.12.1998, p. 147-150.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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