Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. Journal article
  2. Published

    Pardaxin permeabilizes vesicles more efficiently by pore formation than by disruption. / Vad, Brian S; Bertelsen, Kresten; Johansen, Charlotte Hau; Pedersen, Jan Mondrup; Skrydstrup, Troels; Nielsen, Niels Christian; Otzen, Daniel E.

    In: Biophysical Journal, Vol. 98, No. 4, 17.02.2010, p. 576-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Phospholipid Ether Linkages Significantly Modulate the Membrane Affinity of the Antimicrobial Peptide Novicidin. / Vad, Brian S; Balakrishnan, Vijay S; Nielsen, Søren Bang; Otzen, Daniel.

    In: Journal of Membrane Biology, 06.2015, p. 487-496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Flexibility of the thrombin-activatable fibrinolysis inhibitor pro-domain enables productive binding of protein substrates. / Valnickova, Zuzana; Sanglas, Laura; Arolas, Joan L; Petersen, Steen V; Schar, Christine; Otzen, Daniel; Aviles, Francesc X; Gomis-Ruth, F Xavier; Enghild, Jan J.

    In: Journal of Biological Chemistry, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Heparin binding induces a conformational change in pigment epithelium-derived factor. / Valnickova, Zuzana; Petersen, Steen V.; Nielsen, Søren B.; Otzen, Daniel E.; Enghild, Jan J.

    In: Journal of Biological Chemistry, Vol. 282, No. 9, 02.03.2007, p. 6661-6667.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Heparin binding induces a conformational change of pigment epithelium-derived factor (PEDF). / Valnickova, Zuzana; Petersen, Steen Vang; Nielsen, SB; Otzen, Daniel; Enghild, Jan J.

    In: Journal of Biological Chemistry, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Per-glycosylation of the Surface-Accessible Lysines : One-Pot Aqueous Route to Stabilized Proteins with Native Activity. / Walther, Raoul; Monge, Pere; Pedersen, Andreas; Benderoth, Anja; Pedersen, Jannik; Farzadfard, Azad; Mandrup, Ole; Howard, Kenneth; Otzen, Daniel; Zelikin, Alexander N.

    In: ChemBioChem, Vol. 22, No. 14, 07.2021, p. 2478-2485.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    OmpA can form folded and unfolded oligomers. / Wang, H.; Andersen, Kell Kleiner; Vad, B.S.; Otzen, D.E.

    In: B B A - Proteins and Proteomics, Vol. 1834, No. 1, 01.01.2013, p. 127-136.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Soft Interactions at Nanoparticles Alter Protein Function and Conformation in a Size Dependent Manner. / Wang, Jing; Jensen, Uffe B; Jensen, Grethe V; Shipovskov, Stepan; Balakrishnan, Vijay S; Otzen, Daniel; Pedersen, Jan Skov; Besenbacher, Flemming; Sutherland, Duncan S.

    In: Nano Letters, Vol. 11, No. 11, 2011, p. 4985-4991.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Variant of the Thermomyces lanuginosus lipase with improved kinetic stability : a candidate for enzyme replacement therapy. / Wang, Huabing; Hagedorn, J; Svendsen, A; Borch, K; Otzen, Daniel.

    In: Biophysical Chemistry, Vol. 172, 02.2013, p. 43-52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    pH regulation of the kinetic stability of the lipase from Thermomyces lanuginosus. / Wang, H.; Andersen, Kell Kleiner; Sehgal, P.; Hagedorn, Jörg; Westh, Peter; Borch, K.; Otzen, D.E.

    In: Biochemistry, Vol. 52, No. 1, 08.01.2013, p. 264-276.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    A Ser residue influences the structure and stability of a Pro-kinked transmembrane helix dimer. / Weber, Mathias; Tome, Lydia; Otzen, Daniel; Schneider, Dirk.

    In: BBA General Subjects, Vol. 1818, No. 9, 2012, p. 2103-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    SDS-facilitated in vitro formation of a transmembrane B-type cytochrome is mediated by changes in local pH. / Weber, M.; Schneider, D.; Prodöhl, A.; Dreher, Carsten; Becker, Claus; Underhaug, J.; Svane, A.S.P.; Malmendal, A.; Nielsen, Niels Christian; Otzen, D.

    In: Journal of Molecular Biology, Vol. 407, No. 4, 2011, p. 594-606.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    In vitro and in silico assessment of the developability of a designed monoclonal antibody library. / Wolf Pérez, Adriana-Michelle; Sormanni, Pietro; Andersen, Jonathan Sonne; Sakhnini, Laila Ismail; Rodriguez-Leon, Ileana; Bjelke, Jais Rose; Gajhede, Annette Juhl; De Maria, Leonardo; Otzen, Daniel E; Vendruscolo, Michele; Lorenzen, Nikolai.

    In: mAbs, Vol. 11, No. 2, 2019, p. 388-400.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness. / Zeng, Guanghong; Vad, Brian S; Dueholm, Morten S; Christiansen, Gunna; Nilsson, Martin; Tolker-Nielsen, Tim; Nielsen, Per H; Meyer, Rikke L; Otzen, Daniel E.

    In: Frontiers in Microbiology, Vol. 6, 07.10.2015, p. 1099.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Coexistence of ribbon and helical fibrils originating from hIAPP20-29 revealed by quantitative nanomechanical atomic force microscopy. / Zhang, Shuai; Andreasen, Maria; Nielsen, Jakob T; Liu, Lei; Nielsen, Erik H; Song, Jie; Ji, Gang; Sun, Fei; Skrydstrup, Troels; Besenbacher, Flemming; Nielsen, Niels C; Otzen, Daniel E; Dong, Mingdong.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 8, 2013, p. 2798-2803.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    The interactome of stabilized α-synuclein oligomers and neuronal proteins. / van Diggelen, Femke; Frank, Signe Andrea; Somavarapu, Arun Kumar; Scavenius, Carsten; Apetri, Mihaela M; Nielsen, Janni; Tepper, Armand W J W; Enghild, Jan J; Otzen, Daniel E.

    In: The FEBS Journal, Vol. 287, No. 10, 2020, p. 2037-2054.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation. / van Diggelen, Femke; Hrle, Dean; Apetri, Mihaela; Christiansen, Gunna; Rammes, Gerhard; Tepper, Armand; Otzen, Daniel Erik.

    In: PLOS ONE, Vol. 14, No. 3, 0213663, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    α-Synuclein Oligomers : A Study in Diversity. / van Diggelen, Femke; Tepper, Armand; Petri, Mihaela; Otzen, Daniel.

    In: Israel Journal of Chemistry, Vol. 57, No. 7-8, 07.2017, p. 699-723.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth. / van Gils, Juami Hermine Mariama; van Dijk, Erik; Peduzzo, Alessia; Hofmann, Alexander; Vettore, Nicola; Schützmann, Marie P; Groth, Georg; Mouhib, Halima; Otzen, Daniel E; Buell, Alexander K; Abeln, Sanne.

    In: PLOS Computational Biology, Vol. 16, No. 5, e1007767, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Review
  22. Published

    α-synuclein oligomers and fibrils : a spectrum of species, a spectrum of toxicities. / Alam, Parvez; Bousset, Luc; Melki, Ronald; Otzen, Daniel E.

    In: Journal of Neurochemistry, Vol. 150, No. 5, 09.2019, p. 522-534.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  23. Published

    Half a century of amyloids : past, present and future. / Ke, Pu Chun; Zhou, Ruhong; Serpell, Louise C; Riek, Roland; Knowles, Tuomas P J; Lashuel, Hilal A; Gazit, Ehud; Hamley, Ian W; Davis, Thomas P; Fändrich, Marcus; Otzen, Daniel Erik; Chapman, Matthew R; Dobson, Christopher M; Eisenberg, David S; Mezzenga, Raffaele.

    In: Chemical Society Reviews, Vol. 49, No. 15, 07.08.2020, p. 5473-5509.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  24. Published

    MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments. / Martins, Pedro M; Navarro, Susanna; Silva, Alexandra; Pinto, Maria F; Sárkány, Zsuzsa; Figueiredo, Francisco; Pereira, Pedro José Barbosa; Pinheiro, Francisca; Bednarikova, Zuzana; Burdukiewicz, Michał; Galzitskaya, Oxana V; Gazova, Zuzana; Gomes, Cláudio M; Pastore, Annalisa; Serpell, Louise C; Skrabana, Rostislav; Smirnovas, Vytautas; Ziaunys, Mantas; Otzen, Daniel E; Ventura, Salvador; Macedo-Ribeiro, Sandra.

    In: Frontiers in Molecular Neuroscience, Vol. 13, 582488, 27.11.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  25. Published

    Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies. / Nielsen, Nadia Sukusu; Poulsen, Ebbe Toftgaard; Lukassen, Marie V; Chao Shern, Connie; Mogensen, Emilie Hage; Weberskov, Christian E; DeDionisio, Larry; Schauser, Leif; Moore, Tara C B; Otzen, Daniel E; Hjortdal, Jesper; Enghild, Jan J.

    In: Progress in Retinal and Eye Research, Vol. 77, 100843, 07.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  26. E-pub ahead of print

    Microfluidics and the quantification of biomolecular interactions. / Otzen, Daniel E; Buell, Alexander K; Jensen, Henrik.

    In: Current Opinion in Structural Biology, Vol. 70, 05.04.2021, p. 8-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  27. Published

    Structures and mechanisms of formation of liprotides. / Pedersen, Jannik Nedergaard; Frislev, Henriette Kristina Søster; Pedersen, Jan Skov; Otzen, Daniel.

    In: B B A - Proteins and Proteomics, Vol. 1868, No. 11, 140505, 11.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review