Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. Journal article › Research › Peer-reviewed
  2. Published

    N- and C-Terminal Hydrophobic Patches Are Involved in Fibrillation of Glucagon. / Pedersen, Jesper Søndergaard; Dikov, Dancho; Otzen, Daniel.

    In: Biochemistry, Vol. 45, No. 48, 2006, p. 14503-14512.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Nanosilver Mitigates Biofilm Formation via FapC Amyloidosis Inhibition. / Huma, Zil-E; Javed, Ibrahim; Zhang, Zhenzhen; Bilal, Hajira; Sun, Yunxiang; Hussain, Syed Zajif; Davis, Thomas P; Otzen, Daniel E; Landersdorfer, Cornelia B; Ding, Feng; Hussain, Irshad; Ke, Pu Chun.

    In: Small (Weinheim an der Bergstrasse, Germany), Vol. 16, No. 21, 1906674, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Nature and Consequences of GroEL-Protein Interactions. / Itzhaki, Laura S.; Otzen, Daniel E.; Fersht, Alan R.

    In: Biochemistry, Vol. 34, No. 44, 01.01.1995, p. 14581-14587.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Near-complete 1H, 13C, 15N resonance assignments of dimethylsulfoxide-denatured TGFBIp FAS1-4 A546T. / Kulminskaya, Natalia V; Yoshimura, Yuichi; Runager, Kasper; Sørensen, Charlotte S; Bjerring, Morten; Andreasen, Maria; Otzen, Daniel E; Enghild, Jan J; Nielsen, Niels Christian; Mulder, Frans A A.

    In: Biomolecular N M R Assignments, Vol. 10, No. 1, 2016, p. 25-29.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Novel noscapine derivatives stabilize the native state of insulin against fibrillation. / Alijanvand, Saeid Hadi; Christensen, Mikkel Hovden; Christiansen, Gunna; Harikandei, Kosar Babanezhad; Salehi, Peyman; Schiøtt, Birgit; Moosavi-Movahedi, Ali Akbar; Otzen, Daniel E.

    In: International Journal of Biological Macromolecules, Vol. 147, 03.2020, p. 98-108.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Novicidin's membrane permeabilizing activity is driven by membrane partitioning but not by helicity : A biophysical study of the impact of lipid charge and cholesterol. / Balakrishnan, Vijay S; Vad, Brian S; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 6, 02.04.2013, p. 996-1002.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Occupancy of non-annular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein. / Otzen, Daniel.

    In: Biochemistry, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein. / Triano, I.; Barrera, F. N.; Renart, M. L.; Molina, M. L.; Fernández-Ballester, G.; Poveda, J. A.; Fernández, A. M.; Encinar, J. A.; Ferrer-Montiel, A. V.; Otzen, D.; González-Ros, J. M.

    In: Biochemistry, Vol. 49, No. 25, 29.06.2010, p. 5397-5404.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Off-pathway aggregation can inhibit fibrillation at high protein concentrations. / Deva, Taru; Lorenzen, Nikolai; Vad, Brian S; Petersen, Steen V; Thørgersen, Ida; Enghild, Jan J; Kristensen, Torsten; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 3, 03.2013, p. 677-687.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. / Mohammad-Beigi, Hossein; Aliakbari, Farhang; Sahin, Cagla; Lomax, Charlotte; Tawfike, Ahmed; P. Schafer, Nicholas; Amiri-Nowdijeh, Alireza; Eskandari, Hoda; Møller, Ian Max; Hosseini-Mazinani, Mehdi; Christiansen, Gunna; Ward, Jane L; Morshedi, Dina; Otzen, Daniel.

    In: Journal of Biological Chemistry, Vol. 294, No. 11, 2019, p. 4215-4232.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Oligomers of α-synuclein : picking the culprit in the line-up. / Lorenzen, Nikolai; Otzen, Daniel.

    In: Essays in Biochemistry, Vol. 56, No. 1, 18.08.2014, p. 137-148.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    OmpA can form folded and unfolded oligomers. / Wang, H.; Andersen, Kell Kleiner; Vad, B.S.; Otzen, D.E.

    In: B B A - Proteins and Proteomics, Vol. 1834, No. 1, 01.01.2013, p. 127-136.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    PP3 forms stable tetrameric structures through hydrophobic interactions via the C-terminal amphipathic helix and undergoes reversible thermal dissociation and denaturation. / Pedersen, Lise R L; Nielsen, Søren Bang; Hansted, Jon Gade; Petersen, Torben E; Otzen, Daniel E; Sørensen, Esben S.

    In: F E B S Journal, Vol. 279, No. 2, 2012, p. 336-47.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Pardaxin permeabilizes vesicles more efficiently by pore formation than by disruption. / Vad, Brian S; Bertelsen, Kresten; Johansen, Charlotte Hau; Pedersen, Jan Mondrup; Skrydstrup, Troels; Nielsen, Niels Christian; Otzen, Daniel E.

    In: Biophysical Journal, Vol. 98, No. 4, 17.02.2010, p. 576-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Peak Force Infrared - Kelvin Probe Force Microscopy. / Jakob, Devon S; Wang, Haomin; Zeng, Guanghong; Otzen, Daniel E; Yan, Yong; Xu, Xiaoji.

    In: Angewandte Chemie International Edition, Vol. 59, No. 37, 09.2020, p. 16083-16090.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Per-glycosylation of the Surface-Accessible Lysines : One-Pot Aqueous Route to Stabilized Proteins with Native Activity. / Walther, Raoul; Monge, Pere; Pedersen, Andreas; Benderoth, Anja; Pedersen, Jannik; Farzadfard, Azad; Mandrup, Ole; Howard, Kenneth; Otzen, Daniel; Zelikin, Alexander N.

    In: ChemBioChem, Vol. 22, No. 14, 07.2021, p. 2478-2485.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin. / He, Jianfei; Becares, Eva Ramos; Thulstrup, Peter Waaben; Gamon, Luke F.; Pedersen, Jannik Nedergaard; Otzen, Daniel; Gourdon, Pontus; Davies, Michael J.; Hägglund, Per.

    In: Redox Biology, Vol. 36, 101631, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Phospholipid Ether Linkages Significantly Modulate the Membrane Affinity of the Antimicrobial Peptide Novicidin. / Vad, Brian S; Balakrishnan, Vijay S; Nielsen, Søren Bang; Otzen, Daniel.

    In: Journal of Membrane Biology, 06.2015, p. 487-496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Physical Determinants of Amyloid Assembly in Biofilm Formation. / Andreasen, Maria; Meisl, Georg; Taylor, Jonathan D; Michaels, Thomas C T; Levin, Aviad; Otzen, Daniel E; Chapman, Matthew R; Dobson, Christopher M; Matthews, Steve J; Knowles, Tuomas P J.

    In: mBio, Vol. 10, No. 1, e02279-18, 08.01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Plant polyphenols inhibit functional amyloid and biofilm formation in Pseudomonas strains by directing monomers to off-pathway oligomers. / Najarzadeh, Zahra; Mohammad-Beigi, Hossein; Pedersen, Jannik Nedergaard; Christiansen, Gunna; Sønderby, Thorbjørn Vincent; Shojaosadati, Seyed Abbas; Morshedi, Dina; Strømgaard, Kristian; Meisl, Georg; Sutherland, Duncan; Pedersen, Jan Skov; Otzen, Daniel.

    In: Biomolecules, Vol. 9, No. 11, 659, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways with Different Oligomeric Intermediates. / Andreasen, Maria; Nielsen, Søren Bang; Runager, Kasper; Christiansen, Gunna; Nielsen, Niels Christian; Enghild, Jan J; Otzen, Daniel.

    In: Journal of Biological Chemistry, Vol. 287, No. 41, 05.10.2012, p. 34730-34742.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State. / Kurnik, Martin; Sahin, Cagla; Andersen, Camilla Bertel; Lorenzen, Nikolai; Giehm, Lise; Mohammad-Beigi, Hossein; Jessen, Christian Moestrup; Pedersen, Jan Skov; Christiansen, Gunna; Petersen, Steen Vang; Staal, Roland; Krishnamurthy, Girija; Pitts, Keith; Reinhart, Peter H; Mulder, Frans A A; Mente, Scot; Hirst, Warren D; Otzen, Daniel E.

    In: Cell Chemical Biology, Vol. 25, No. 11, 15.11.2018, p. 1389-1402.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Predicted Loop Regions Promote Aggregation : A Study of Amyloidogenic Domains in the Functional Amyloid FapC. / Nagaraj, Madhu; Ahmed, Mumdooh; Lyngsø, Jeppe; Vad, Brian Stougaard; Bøggild, Andreas; Fillipsen, Anne; Pedersen, Jan Skov; Otzen, Daniel Erik; Akbey, Ümit.

    In: Journal of Molecular Biology, Vol. 432, No. 7, 2020, p. 2232-2252.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. / Cohen, Samuel I A; Linse, Sara; Luheshi, Leila M; Hellstrand, Erik; White, Duncan A; Rajah, Luke; Otzen, Daniel; Vendruscolo, Michele; Dobson, Christopher M; Knowles, Tuomas P J.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 24, 23.05.2013, p. 9758-9763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Promoting protein self-association in non-glycosylated Thermomyces lanuginosus lipase based on crystal lattice contacts. / Madsen, Jens; Sørensen, Thomas Rebsdorf; Kaspersen, Jørn Døvling; Silow, Maria Berggård; Vind, Jesper; Pedersen, Jan Skov; Svendsen, Allan; Otzen, Daniel E.

    In: BBA Proteins and Proteomics, Vol. 154, No. 12, 12.2015, p. 1914-1921.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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