Daniel Otzen

  1. Journal article › Research › Peer-reviewed
  2. Published

    The bacterial amyloids phenol soluble modulins from staphylococcus aureus catalyze alpha-synuclein aggregation. / Haikal, Caroline; Pascual, Lei Ortigosa; Najarzadeh, Zahra; Bernfur, Katja; Svanbergsson, Alexander; Otzen, Daniel E.; Linse, Sara; Li, Jia Yi.

    In: International Journal of Molecular Sciences, Vol. 22, No. 21, 11594, 11.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    The compact and biologically relevant structure of inter-α-inhibitor is maintained by the chondroitin sulfate chain and divalent cations. / Scavenius, Carsten; Nikolajsen, Camilla Lund; Stenvang, Marcel; Thøgersen, Ida; Wyrozemski, Lukasz; Wisniewski, Hans-Georg; Otzen, Daniel E; Sanggaard, Kristian W; Enghild, Jan J.

    In: Journal of Biological Chemistry, Vol. 291, No. 9, 26.02.2016, p. 4658-4670.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    The diversity of FtsY-lipid interactions. / Reinau, M E; Thøgersen, I B; Enghild, J J; Nielsen, K L; Otzen, D E.

    In: Biopolymers, Vol. 93, No. 7, 01.07.2010, p. 595-606.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    The effect of osmolytes on protein fibrillation. / Macchi, Francesca; Eisenkolb, Maike; Kiefer, Hans; Otzen, Daniel.

    In: International Journal of Molecular Sciences (Online), Vol. 13, No. 3, 21.03.2012, p. 3801-3819.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth. / van Gils, Juami Hermine Mariama; van Dijk, Erik; Peduzzo, Alessia; Hofmann, Alexander; Vettore, Nicola; Schützmann, Marie P; Groth, Georg; Mouhib, Halima; Otzen, Daniel E; Buell, Alexander K; Abeln, Sanne.

    In: PLOS Computational Biology, Vol. 16, No. 5, e1007767, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    The influence of vesicle composition and size on a-synuclein structure and stability. / Kjær, Lars; Giehm, Lise; Heimburg, Thomas Rainer; Otzen, Daniel.

    In: Biophysical Journal, Vol. 96, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    The interaction of equine lysozyme:oleic acid complexes with lipid membranes suggests a cargo off-loading mechanism. / Nielsen, Søren Bang; Wilhelm, Kristina; Vad, Brian; Schleucher, Jürgen; Morozova-Roche, Ludmilla A; Otzen, Daniel.

    In: Journal of Molecular Biology, Vol. 398, No. 2, 2010, p. 351-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    The interactome of stabilized α-synuclein oligomers and neuronal proteins. / van Diggelen, Femke; Frank, Signe Andrea; Somavarapu, Arun Kumar; Scavenius, Carsten; Apetri, Mihaela M; Nielsen, Janni; Tepper, Armand W J W; Enghild, Jan J; Otzen, Daniel E.

    In: The FEBS Journal, Vol. 287, No. 10, 2020, p. 2037-2054.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    The length distribution of frangible biofilaments. / Michaels, Thomas C T; Yde, Pernille; Willis, Julian C W; Jensen, Mogens H; Otzen, Daniel; Dobson, Christopher M; Buell, Alexander K; Knowles, Tuomas P J.

    In: Journal of Chemical Physics, Vol. 143, No. 16, 164901, 28.10.2015, p. 1-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands. / Mogensen, Jesper E.; Wimmer, Reinhard; Larsen, Jørgen N.; Spangfort, Michael D.; Otzen, Daniel E.

    In: Journal of Biological Chemistry, Vol. 277, No. 26, 28.06.2002, p. 23684-23692.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    The natural, peptaibolic peptide SPF-5506-A4 adopts a β-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores. / Frahm, Heidi; Hansen, Sara K; Vad, Brian S; Nielsen, Erik H; Nielsen, Jakob T; Vosegaard, Thomas; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 8, 08.2015, p. 882-889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity. / Jarvela, Timothy S; Lam, Hoa A; Helwig, Michael; Lorenzen, Nikolai; Otzen, Daniel E; McLean, Pamela J; Maidment, Nigel T; Lindberg, Iris.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 32, 25.07.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. / Helwig, Michael; Hoshino, Akino; Berridge, Casey; Lee, Sang-Nam; Lorenzen, Nikolai; Otzen, Daniel; Eriksen, Jason; Lindberg, Iris.

    In: Journal of Biological Chemistry, Vol. 288, No. 2, 11.01.2013, p. 1114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. / Aliakbari, Farhang; Mohammad-Beigi, Hossein; Rezaei-Ghaleh, Nasrollah; Becker, Stefan; Dehghani Esmatabad, Faezeh; Eslampanah Seyedi, Hadieh Alsadat; Bardania, Hassan; Tayaranian Marvian, Amir; Collingwood, Joanna F; Christiansen, Gunna; Zweckstetter, Markus; Otzen, Daniel E; Morshedi, Dina.

    In: Nanoscale, Vol. 10, No. 19, 17.05.2018, p. 9174-9185.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage. / Christiansen, Stig Hill; Zhang, Xianwei; Juul-Madsen, Kristian; Hvam, Michael Lykke; Vad, Brian Stougaard; Behrens, Manja Annette; Thygesen, Ida Lysgaard; Jalilian, Babak; Pedersen, Jan Skov; Howard, Ken; Otzen, Daniel E; Vorup-Jensen, Thomas.

    In: B B A - Biomembranes, Vol. 1859, No. 3, 03.2017, p. 425-437.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    The role of decorated SDS micelles in sub-cmc protein denaturation and association. / Andersen, Kell; Oliveira, Cristiano Luis Pinto De; Larsen, Kim Lambertsen; Poulsen, Flemming; Callisen, Thomas; Westh, Peter; Pedersen, Jan Skov; Otzen, Daniel.

    In: Journal of Molecular Biology, Vol. 391, 2009, p. 207-226.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    The role of membrane properties in Mistic folding and dimerisation. / Debnath, Dilip Kumar; Basaiawmoit, Rajiv Vaid; Nielsen, Kåre Lehmann; Otzen, Daniel E.

    In: Protein Engineering Design and Selection (Print), Vol. 24, No. 1-2, 01.01.2011, p. 89-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    The role of protonation in protein fibrillation. / Jeppesen, Martin D; Westh, Peter; Otzen, Daniel E.

    In: FEBS Letters, Vol. 584, No. 4, 19.02.2010, p. 780-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. / Lorenzen, Nikolai; Nielsen, Søren Bang; Buell, Alexander K. ; Kaspersen, Jørn Døvling; Arosio, Paolo; Vad, Brian Stougaard; Paslawski, Wojciech; Christiansen, Gunna; Valnickova Hansen, Zuzana; Andreasen, Maria; Enghild, Jan Johannes; Pedersen, Jan Skov; Dobson, Christopher M; Knowles, Tuomas P J; Otzen, Daniel.

    In: Journal of the American Chemical Society, Vol. 136, No. 10, 16.02.2014, p. 3859-3868.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    The spectral and thermodynamic properties of staphylococcal enterotoxin A, E, and variants suggest that structural modifications are important to control their function. / Cavallin, Anders; Arozenius, Helena; Kristensson, Karin; Antonsson, Per; Otzen, Daniel E.; Björk, Per; Forsberg, Göran.

    In: Journal of Biological Chemistry, Vol. 275, No. 3, 21.01.2000, p. 1665-1672.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization. / Marvian, Amir Tayaranian; Aliakbari, Farhang; Mohammad-Beigi, Hossein; Ahmadi, Zeinab Alsadat; Mehrpouyan, Sina; Lermyte, Frederik; Nasouti, Mahour; Collingwood, Joanna F; Otzen, Daniel E; Morshedi, Dina.

    In: International Journal of Biological Macromolecules, Vol. 155, 07.2020, p. 543-550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods : Evidence for a nucleation-condensation mechanism for protein folding. / Itzhaki, Laura S.; Otzen, Daniel E.; Fersht, Alan R.

    In: Journal of Molecular Biology, Vol. 254, No. 2, 24.11.1995, p. 260-288.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    The transcriptional regulator GalR self-assembles to form highly regular tubular structures. / Agerschou, Emil D; Christiansen, Gunna; Schafer, Nicholas P; Madsen, Daniel Jhaf; Brodersen, Ditlev E; Semsey, Szabolcs; Otzen, Daniel E.

    In: Scientific Reports, Vol. 6, 27672, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Thermodynamics and mechanism of cutinase stabilization by trehalose. / Baptista, R. P.; Pedersen, S. H.; Cabrita, G. J. M.; Otzen, Daniel; Cabral, J. M.; Melo, E. P.

    In: Biopolymers, Vol. 89, 2008, p. 538-547.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Thermodynamics of unfolding of an integral membrane protein in mixed micelles. / Sehgal, Pankaj; Otzen, Daniel.

    In: Protein Science, Vol. 15, 2006, p. 890-899.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review