Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. Journal article › Research › Peer-reviewed
  2. Published

    The natural, peptaibolic peptide SPF-5506-A4 adopts a β-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores. / Frahm, Heidi; Hansen, Sara K; Vad, Brian S; Nielsen, Erik H; Nielsen, Jakob T; Vosegaard, Thomas; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 8, 08.2015, p. 882-889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity. / Jarvela, Timothy S; Lam, Hoa A; Helwig, Michael; Lorenzen, Nikolai; Otzen, Daniel E; McLean, Pamela J; Maidment, Nigel T; Lindberg, Iris.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 32, 25.07.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. / Helwig, Michael; Hoshino, Akino; Berridge, Casey; Lee, Sang-Nam; Lorenzen, Nikolai; Otzen, Daniel; Eriksen, Jason; Lindberg, Iris.

    In: Journal of Biological Chemistry, Vol. 288, No. 2, 11.01.2013, p. 1114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. / Aliakbari, Farhang; Mohammad-Beigi, Hossein; Rezaei-Ghaleh, Nasrollah; Becker, Stefan; Dehghani Esmatabad, Faezeh; Eslampanah Seyedi, Hadieh Alsadat; Bardania, Hassan; Tayaranian Marvian, Amir; Collingwood, Joanna F; Christiansen, Gunna; Zweckstetter, Markus; Otzen, Daniel E; Morshedi, Dina.

    In: Nanoscale, Vol. 10, No. 19, 17.05.2018, p. 9174-9185.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage. / Christiansen, Stig Hill; Zhang, Xianwei; Juul-Madsen, Kristian; Hvam, Michael Lykke; Vad, Brian Stougaard; Behrens, Manja Annette; Thygesen, Ida Lysgaard; Jalilian, Babak; Pedersen, Jan Skov; Howard, Ken; Otzen, Daniel E; Vorup-Jensen, Thomas.

    In: B B A - Biomembranes, Vol. 1859, No. 3, 03.2017, p. 425-437.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    The role of decorated SDS micelles in sub-cmc protein denaturation and association. / Andersen, Kell; Oliveira, Cristiano Luis Pinto De; Larsen, Kim Lambertsen; Poulsen, Flemming; Callisen, Thomas; Westh, Peter; Pedersen, Jan Skov; Otzen, Daniel.

    In: Journal of Molecular Biology, Vol. 391, 2009, p. 207-226.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    The role of membrane properties in Mistic folding and dimerisation. / Debnath, Dilip Kumar; Basaiawmoit, Rajiv Vaid; Nielsen, Kåre Lehmann; Otzen, Daniel E.

    In: Protein Engineering Design and Selection (Print), Vol. 24, No. 1-2, 01.01.2011, p. 89-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    The role of protonation in protein fibrillation. / Jeppesen, Martin D; Westh, Peter; Otzen, Daniel E.

    In: FEBS Letters, Vol. 584, No. 4, 19.02.2010, p. 780-4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. / Lorenzen, Nikolai; Nielsen, Søren Bang; Buell, Alexander K. ; Kaspersen, Jørn Døvling; Arosio, Paolo; Vad, Brian Stougaard; Paslawski, Wojciech; Christiansen, Gunna; Valnickova Hansen, Zuzana; Andreasen, Maria; Enghild, Jan Johannes; Pedersen, Jan Skov; Dobson, Christopher M; Knowles, Tuomas P J; Otzen, Daniel.

    In: Journal of the American Chemical Society, Vol. 136, No. 10, 16.02.2014, p. 3859-3868.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    The spectral and thermodynamic properties of staphylococcal enterotoxin A, E, and variants suggest that structural modifications are important to control their function. / Cavallin, Anders; Arozenius, Helena; Kristensson, Karin; Antonsson, Per; Otzen, Daniel E.; Björk, Per; Forsberg, Göran.

    In: Journal of Biological Chemistry, Vol. 275, No. 3, 21.01.2000, p. 1665-1672.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization. / Marvian, Amir Tayaranian; Aliakbari, Farhang; Mohammad-Beigi, Hossein; Ahmadi, Zeinab Alsadat; Mehrpouyan, Sina; Lermyte, Frederik; Nasouti, Mahour; Collingwood, Joanna F; Otzen, Daniel E; Morshedi, Dina.

    In: International Journal of Biological Macromolecules, Vol. 155, 07.2020, p. 543-550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods : Evidence for a nucleation-condensation mechanism for protein folding. / Itzhaki, Laura S.; Otzen, Daniel E.; Fersht, Alan R.

    In: Journal of Molecular Biology, Vol. 254, No. 2, 24.11.1995, p. 260-288.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    The transcriptional regulator GalR self-assembles to form highly regular tubular structures. / Agerschou, Emil D; Christiansen, Gunna; Schafer, Nicholas P; Madsen, Daniel Jhaf; Brodersen, Ditlev E; Semsey, Szabolcs; Otzen, Daniel E.

    In: Scientific Reports, Vol. 6, 27672, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Thermodynamics and mechanism of cutinase stabilization by trehalose. / Baptista, R. P.; Pedersen, S. H.; Cabrita, G. J. M.; Otzen, Daniel; Cabral, J. M.; Melo, E. P.

    In: Biopolymers, Vol. 89, 2008, p. 538-547.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Thermodynamics of unfolding of an integral membrane protein in mixed micelles. / Sehgal, Pankaj; Otzen, Daniel.

    In: Protein Science, Vol. 15, 2006, p. 890-899.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Transient aggregation and stable dimerization induced by introducing an Alzheimer sequence into a water-soluble protein. / Otzen, Daniel E.; Miron, Simona; Akke, Mikael; Oliveberg, Mikael.

    In: Biochemistry, Vol. 43, No. 41, 19.10.2004, p. 12964-12978.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Transient formation of nano-crystalline structures during fibrillation of an Aβ-like peptide. / Otzen, Daniel E.; Oliveberg, Mikael.

    In: Protein Science, Vol. 13, No. 5, 01.05.2004, p. 1417-1421.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Trehalose favors a cutinase compact intermediate off-folding pathway. / Melo, Eduardo P.; Chen, Lu Yang; Cabral, Joaquim M.S.; Fojan, Peter; Petersen, Steffen B.; Otzen, Daniel E.

    In: Biochemistry, Vol. 42, No. 24, 24.06.2003, p. 7611-7617.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation. / van Diggelen, Femke; Hrle, Dean; Apetri, Mihaela; Christiansen, Gunna; Rammes, Gerhard; Tepper, Armand; Otzen, Daniel Erik.

    In: PLOS ONE, Vol. 14, No. 3, 0213663, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. E-pub ahead of print

    Ubiquitin forms conventional decorated micelle structures with sodium dodecyl sulfate at saturation. / Mortensen, Henriette Gavlshøj; Otzen, Daniel Erik; Pedersen, Jan Skov.

    In: Journal of Colloid and Interface Science, Vol. 596, 24.03.2021, p. 233-244.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Unfolding and partial refolding of a cellulase from the SDS-denatured state : From β-sheet to α-helix and back. / Rasmussen, Helena Ø.; Enghild, Jan J; Otzen, Daniel E; Pedersen, Jan Skov.

    In: B B A - General Subjects, Vol. 1864, No. 1, 129434, 01.2020, p. 129434 1-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Unfolding of ß-sheet proteins in SDS. / Nielsen, M. M.; Andersen, K. K.; Westh, P.; Otzen, Daniel.

    In: Biophysical Journal, No. 92, 2007, p. 3674-3685.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Unique identification of supramolecular structures in amyloid fibrils by solid-state NMR spectroscopy. / Nielsen, Jakob Toudahl; Bjerring, Morten; Jeppesen, Martin; Pedersen, Ronnie O.; Pedersen, Jan Mondrup; Hein, Kim Langmach; Vosegaard, Thomas; Skrydstrup, Troels; Otzen, Daniel; Nielsen, Niels Christian.

    In: Angewandte Chemie International Edition, Vol. 48, 2009, p. 2118-2121.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Using Liprotides to Deliver Cholesterol to the Plasma Membrane. / Frislev, Henriette S.; Nielsen, Janni; Nylandsted, Jesper; Otzen, Daniel.

    In: Journal of Membrane Biology, Vol. 25, No. 4, 08.2018, p. 581-592.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Using micellar mole fractions to assess membrane protein stability in mixed micelles. / Sehgal, Pankaj; Mogensen, Jens Erik; Otzen, Daniel.

    In: B B A - Biomembranes, Vol. 1761, 2005, p. 59-68.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review