Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. Journal article › Research › Peer-reviewed
  2. Published

    OmpA can form folded and unfolded oligomers. / Wang, H.; Andersen, Kell Kleiner; Vad, B.S.; Otzen, D.E.

    In: B B A - Proteins and Proteomics, Vol. 1834, No. 1, 01.01.2013, p. 127-136.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    PP3 forms stable tetrameric structures through hydrophobic interactions via the C-terminal amphipathic helix and undergoes reversible thermal dissociation and denaturation. / Pedersen, Lise R L; Nielsen, Søren Bang; Hansted, Jon Gade; Petersen, Torben E; Otzen, Daniel E; Sørensen, Esben S.

    In: F E B S Journal, Vol. 279, No. 2, 2012, p. 336-47.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Pardaxin permeabilizes vesicles more efficiently by pore formation than by disruption. / Vad, Brian S; Bertelsen, Kresten; Johansen, Charlotte Hau; Pedersen, Jan Mondrup; Skrydstrup, Troels; Nielsen, Niels Christian; Otzen, Daniel E.

    In: Biophysical Journal, Vol. 98, No. 4, 17.02.2010, p. 576-85.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Peak Force Infrared - Kelvin Probe Force Microscopy. / Jakob, Devon S; Wang, Haomin; Zeng, Guanghong; Otzen, Daniel E; Yan, Yong; Xu, Xiaoji.

    In: Angewandte Chemie International Edition, Vol. 59, No. 37, 09.2020, p. 16083-16090.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. E-pub ahead of print

    Per-glycosylation of the Surface-Accessible Lysines : One-Pot Aqueous Route to Stabilized Proteins with Native Activity. / Walther, Raoul; Monge, Pere; Pedersen, Andreas; Benderoth, Anja; Pedersen, Jannik; Farzadfard, Azad; Mandrup, Ole; Howard, Kenneth; Otzen, Daniel; Zelikin, Alexander N.

    In: ChemBioChem, 16.05.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin. / He, Jianfei; Becares, Eva Ramos; Thulstrup, Peter Waaben; Gamon, Luke F.; Pedersen, Jannik Nedergaard; Otzen, Daniel; Gourdon, Pontus; Davies, Michael J.; Hägglund, Per.

    In: Redox Biology, Vol. 36, 101631, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Phospholipid Ether Linkages Significantly Modulate the Membrane Affinity of the Antimicrobial Peptide Novicidin. / Vad, Brian S; Balakrishnan, Vijay S; Nielsen, Søren Bang; Otzen, Daniel.

    In: Journal of Membrane Biology, 06.2015, p. 487-496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Physical Determinants of Amyloid Assembly in Biofilm Formation. / Andreasen, Maria; Meisl, Georg; Taylor, Jonathan D; Michaels, Thomas C T; Levin, Aviad; Otzen, Daniel E; Chapman, Matthew R; Dobson, Christopher M; Matthews, Steve J; Knowles, Tuomas P J.

    In: mBio, Vol. 10, No. 1, e02279-18, 08.01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Plant polyphenols inhibit functional amyloid and biofilm formation in Pseudomonas strains by directing monomers to off-pathway oligomers. / Najarzadeh, Zahra; Mohammad-Beigi, Hossein; Pedersen, Jannik Nedergaard; Christiansen, Gunna; Sønderby, Thorbjørn Vincent; Shojaosadati, Seyed Abbas; Morshedi, Dina; Strømgaard, Kristian; Meisl, Georg; Sutherland, Duncan; Pedersen, Jan Skov; Otzen, Daniel.

    In: Biomolecules, Vol. 9, No. 11, 659, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways with Different Oligomeric Intermediates. / Andreasen, Maria; Nielsen, Søren Bang; Runager, Kasper; Christiansen, Gunna; Nielsen, Niels Christian; Enghild, Jan J; Otzen, Daniel.

    In: Journal of Biological Chemistry, Vol. 287, No. 41, 05.10.2012, p. 34730-34742.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State. / Kurnik, Martin; Sahin, Cagla; Andersen, Camilla Bertel; Lorenzen, Nikolai; Giehm, Lise; Mohammad-Beigi, Hossein; Jessen, Christian Moestrup; Pedersen, Jan Skov; Christiansen, Gunna; Petersen, Steen Vang; Staal, Roland; Krishnamurthy, Girija; Pitts, Keith; Reinhart, Peter H; Mulder, Frans A A; Mente, Scot; Hirst, Warren D; Otzen, Daniel E.

    In: Cell Chemical Biology, Vol. 25, No. 11, 15.11.2018, p. 1389-1402.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Predicted Loop Regions Promote Aggregation : A Study of Amyloidogenic Domains in the Functional Amyloid FapC. / Nagaraj, Madhu; Ahmed, Mumdooh; Lyngsø, Jeppe; Vad, Brian Stougaard; Bøggild, Andreas; Fillipsen, Anne; Pedersen, Jan Skov; Otzen, Daniel Erik; Akbey, Ümit.

    In: Journal of Molecular Biology, Vol. 432, No. 7, 2020, p. 2232-2252.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. / Cohen, Samuel I A; Linse, Sara; Luheshi, Leila M; Hellstrand, Erik; White, Duncan A; Rajah, Luke; Otzen, Daniel; Vendruscolo, Michele; Dobson, Christopher M; Knowles, Tuomas P J.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 24, 23.05.2013, p. 9758-9763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Promoting protein self-association in non-glycosylated Thermomyces lanuginosus lipase based on crystal lattice contacts. / Madsen, Jens; Sørensen, Thomas Rebsdorf; Kaspersen, Jørn Døvling; Silow, Maria Berggård; Vind, Jesper; Pedersen, Jan Skov; Svendsen, Allan; Otzen, Daniel E.

    In: BBA Proteins and Proteomics, Vol. 154, No. 12, 12.2015, p. 1914-1921.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Properties of PEG-modified microbial proteases. Activity and stability studies. / Fatum, T. M.; Olsen, A. Agerlin; Fuglsang, C. C.; Otzen, D.

    In: Progress in Biotechnology, Vol. 15, No. C, 01.12.1998, p. 147-150.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Proteasome-Fibrillation Antagonism in a Dynamic Model for Parkinson’s Disease. / Sneppen, Kim; Lizana, George Ludvig; Jensen, Mogens Høgh; Pigolotti, Simone; Otzen, Daniel.

    In: Physical Biology, Vol. 6, 2009, p. 36005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms. / Bleem, Alissa; Christiansen, Gunna; Madsen, Daniel J; Maric, Hans; Strømgaard, Kristian; Bryers, James D; Daggett, Valerie; Meyer, Rikke L; Otzen, Daniel E.

    In: Journal of Molecular Biology, Vol. 430, No. 20, 12.10.2018, p. 3751-3763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Protein Fragments as Models for Events in Protein Folding Pathways : Protein Engineering Analysis of the Association of Two Complementary Fragments of the Barley Chymotrypsin Inhibitor 2 (CI-2). / Ruiz-Sanz, Javier; de Prat Gay, Gonzalo; Otzen, Daniel E.; Fersht, Alan R.

    In: Biochemistry, Vol. 34, No. 5, 01.01.1995, p. 1695-1701.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Protein aggregation : Close encounters of the greasy kind. / Otzen, Daniel.

    In: Nature Chemical Biology, Vol. 11, No. 3, 17.02.2015, p. 176-177.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Protein drug stability: a formulation challenge. / Frøkjær, Sven; Otzen, Daniel.

    In: Nature Reviews. Drug Discovery, Vol. 4, 2005, p. 298-306.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Protein unfolding in detergents : Effect of micelle structure, ionic strength, pH, and temperature. / Otzen, Daniel E.

    In: Biophysical Journal, Vol. 83, No. 4, 01.10.2002, p. 2219-2230.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Protein-surfactant interactions a tale of many states. / Otzen, Daniel.

    In: BBA General Subjects, Vol. 1814, No. 5, 2011, p. 562-91.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Protein:fatty acid complexes : Biochemistry, biophysics and function. / Brinkmann, Christel Rothe; Thiel, Steffen; Otzen, Daniel.

    In: F E B S Journal, Vol. 280, No. 8, 04.2013, p. 1733–1749.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Proteins in a brave new surfactant world. / Otzen, Daniel E.

    In: Current Opinion in Colloid & Interface Science, Vol. 20, No. 3, 01.06.2015, p. 161-169.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Proteolytic activation of proteose peptone component 3 by release of a C-terminal peptide with antibacterial properties. / Pedersen, Lise Refstrup Linnebjerg; Hansted, J.G.; Nielsen, Søren Bang; Petersen, T.E.; Sørensen, U.S.; Otzen, D.; Sørensen, E.S.

    In: Journal of Dairy Science, Vol. 95, No. 6, 01.06.2012, p. 2819-2829.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Proteomic changes in response to chromium(VI) toxicity in Pseudomonas aeruginosa . / Kilic, Nur; Stensballe, Allan; Otzen, Daniel; Dönmez, G.

    In: Bioresource Technology, Vol. 101, 2009, p. 2134-2140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Pseudomonas aeruginosa rhamnolipid induces fibrillation of human α-synuclein and modulates its effect on biofilm formation. / Andersen, Kell K; Vad, Brian S; Kjaer, Lars; Tolker-Nielsen, Tim; Christiansen, Gunna; Otzen, Daniel E.

    In: FEBS Letters, Vol. 592, No. 9, 05.2018, p. 1484-1496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Purification and Identification of High Molecular Weight Products Formed During Storage of Neutral Formulation of Human Insulin. / Hjorth, Christian Fogt; Hubálek, František; Andersson, Jonatan; Poulsen, Christian; Otzen, Daniel; Naver, Helle.

    In: Pharmaceutical Research, Vol. 32, No. 6, 06.2015, p. 2072-2085.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Quality control system response to stochastic growth of amyloid fibrils. / Pigolotti, Simone; Lizana, Ludvig; Otzen, Daniel; Sneppen, Kim.

    In: F E B S Letters, Vol. 587, No. 9, 02.05.2013, p. 1405-1410.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Quantitating denaturation by formic acid : Imperfect repeats are essential to the stability of the functional amyloid protein FapC. / Christensen, Line Friis Bakmann; Nowak, Jan Stanislaw; Sønderby, Thorbjørn Vincent; Frank, Signe Andrea; Otzen, Daniel Erik.

    In: The Journal of biological chemistry, Vol. 295, No. 37, 09.2020, p. 13031–13046.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Quantitative use of paramagnetic relaxation enhancements for determining orientation and insertion depth of peptides in micelles. / Franzmann, Magnus; Otzen, Daniel; Wimmer, Reinhard.

    In: ChemBioChem, Vol. 10, 2009, p. 2339-2347.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Quartz crystal microbalance studies of multilayer glucagon fibrillation at the solid-liquid interface. / Hovgaard, Mads Bruun; Dong, Mingdong; Otzen, Daniel Erik; Besenbacher, Flemming.

    In: Biophysical Journal, Vol. 93, No. 6, 2007, p. 2162-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Quartz crystal microbalance studies of multilayer glucagons fibrillation at the solid-liquid interface. / Hovgaard, Mads Bruun; Dong, Mingdong; Otzen, Daniel; Besenbacher, Flemming.

    In: Biophysical Journal, Vol. 93, No. 6, 2007, p. 2162.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Rate of isomerisation of peptidyl-proline bonds as a probe for interactions in the physiological denatured state of chymotrypsin inhibitor 2. / Tan, Yee Joo; Oliveberg, Mikael; Otzen, Daniel E.; Fersht, Alan R.

    In: Journal of Molecular Biology, Vol. 269, No. 4, 20.06.1997, p. 611-622.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation. / Christensen, Line Friis Bakmann; Jensen, Kirstine Friis; Nielsen, Janni; Vad, Brian Stougaard; Christiansen, Gunna; Otzen, Daniel Erik.

    In: ACS Omega, Vol. 4, No. 2, 02.2019, p. 4029-4039.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Refolding of SDS-Unfolded Proteins by Nonionic Surfactants. / Kaspersen, Jørn Døvling; Søndergaard, Anne; Madsen, Daniel Jhaf; Otzen, Daniel E; Pedersen, Jan Skov.

    In: Biophysical Journal, Vol. 112, No. 8, 25.04.2017, p. 1609-1620.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Role of charge and hydrophobicity in liprotide formation : a molecular dynamics study with experimental constraints. / Nedergaard Pedersen, Jannik; Wilhelmus Johannes Maria Frederix, Pim; Skov Pedersen, Jan; Marrink, Siewert Jan; Otzen, Daniel.

    In: ChemBioChem, Vol. 19, No. 3, 02.02.2018, p. 263–271.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Role of elongation and secondary pathways in S6 amyloid fibril growth. / Lorenzen, N.; Cohen, S.I.A.; Nielsen, Søren Bang; Herling, T.W.; Christiansen, G.; Dobson, C.M.; T. P. Knowles, Tuomas; Otzen, D.

    In: Biophysical Journal, Vol. 102, No. 9, 02.05.2012, p. 2167-2175.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    SAXS Study of Glucagon Fibrillation : From Monomers to Fibers. / Oliveira, Cristiano Luis Pinto De; Behrens, Manja Annette; Pedersen, Jesper Søndergaard; Erlacher, Kurt; Otzen, Daniel; Pedersen, Jan Skov.

    In: Journal of Molecular Biology, Vol. 387, 2009, p. 147-161.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    SAXS models of TGFBIp reveal a trimeric structure and show that the overall shape is not affected by the Arg124His mutation. / Basaiawmoit, R.V.; Oliveira, C.L.P.; Runager, K.; Sørensen, C.S.; Behrens, Manja Annette; Jonsson, B.-H.; Kristensen, T.; Klintworth, G.K.; Enghild, J.J.; Pedersen, Jan Skov; Otzen, Daniel Erik.

    In: Journal of Molecular Biology, Vol. 408, No. 3, 2011, p. 503-513.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    SDS-Induced Fibrillation of α-Synuclein: An Alternative Fibrillation Pathway. / Giehm, Lise; Oliveira, Cristiano Luis Pinto De; Christiansen, Gunna; Pedersen, Jan Skov; Otzen, Daniel.

    In: Journal of Molecular Biology, Vol. 401, 2010, p. 115-133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    SDS-facilitated in vitro formation of a transmembrane B-type cytochrome is mediated by changes in local pH. / Weber, M.; Schneider, D.; Prodöhl, A.; Dreher, Carsten; Becker, Claus; Underhaug, J.; Svane, A.S.P.; Malmendal, A.; Nielsen, Niels Christian; Otzen, D.

    In: Journal of Molecular Biology, Vol. 407, No. 4, 2011, p. 594-606.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    SDS-induced multi-stage unfolding of a small globular protein through different denatured states revealed by single-molecule fluorescence. / Krainer, Georg; Hartmann, Andreas; Bogatyr, Vadim; Nielsen, Janni; Schlierf, Michael; Otzen, Daniel E.

    In: Chemical Science, Vol. 11, No. 34, 09.2020, p. 9141-9153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Salt-induced detour through compact regions of the protein folding landscape. / Otzen, Daniel E.; Oliveberg, Mikael.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 21, 12.10.1999, p. 11746-11751.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Scaffolded multimers of hIAPP20-29 peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP20-29 peptide fragment. / Christoffersen, Heidi F; Andreasen, Maria; Zhang, Shuai; Nielsen, Erik Holm; Christiansen, Gunna; Dong, Mingdong; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 12, 12.2015, p. 1890-1897.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Scanning Tunneling Microscopy Reveals Single-Molecule Insights into the Self-Assembly of Amyloid Fibrils. / Kalashnyk, Nataliya; Nielsen, Jakob T; Nielsen, Erik H; Skrydstrup, Troels; Otzen, Daniel; Lægsgaard, Erik; Wang, Chen; Besenbacher, Flemming; Nielsen, Niels Christian; Linderoth, Trolle R.

    In: A C S Nano, 2012, p. 6882-6889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. Published

    Scanning tunneling microscopy reveals single-molecule insights into the self-assembly of amyloid fibrils. / Kalashnyk, N.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T.R.; Nielsen, J.T.; Nielsen, Erik Holm Toustrup; Skrydstrup, T.; Nielsen, N.C.; Otzen, D.E.; Wang, C.

    In: A C S Nano, Vol. 6, No. 8, 28.08.2012, p. 6882-6889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation. / Kronqvist, Nina; Otikovs, Martins; Chmyrov, Volodymyr; Chen, Gefei; Andersson, Marlene; Nordling, Kerstin; Landreh, Michael; Sarr, Médoune; Jörnvall, Hans; Wennmalm, Stefan; Widengren, Jerker; Meng, Qing; Rising, Anna; Otzen, Daniel; Knight, Stefan D; Jaudzems, Kristaps; Johansson, Jan.

    In: Nature Communications, Vol. 5, 3254, 10.02.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Side-Chain Determinants of β-Sheet Stability. / Otzen, Daniel E.; Fersht, Alan R.

    In: Biochemistry, Vol. 34, No. 17, 01.05.1995, p. 5718-5724.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. Published

    Single versus parallel pathways of protein folding and fractional formation of structure in the transition state. / Fersht, Alan R.; Itzhaki, Laura S.; Elmasry, Nadia F.; Matthews, Jacqueline M.; Otzen, Daniel E.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 22, 25.10.1994, p. 10426-10429.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4. / Juul-Madsen, Kristian; Qvist, Per; Bendtsen, Kirstine L; Langkilde, Annette E; Vestergaard, Bente; Howard, Ken; Dehesa-Etxebeste, Martxel; Paludan, Søren R; Andersen, Gregers Rom; Jensen, Poul Henning; Otzen, Daniel E; Romero-Ramos, Marina; Vorup-Jensen, Thomas.

    In: Journal of Immunology, Vol. 204, No. 5, 2020, p. 1345-1361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Soft Interactions at Nanoparticles Alter Protein Function and Conformation in a Size Dependent Manner. / Wang, Jing; Jensen, Uffe B; Jensen, Grethe V; Shipovskov, Stepan; Balakrishnan, Vijay S; Otzen, Daniel; Pedersen, Jan Skov; Besenbacher, Flemming; Sutherland, Duncan S.

    In: Nano Letters, Vol. 11, No. 11, 2011, p. 4985-4991.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Specific incorporation of kinetin into eukaryotic and prokaryotic transfer ribonucleic acid molecules. / Barciszewski, J.; Otzen, D.; Rattan, S. I.S.; Clark, B. F.C.

    In: Biochemistry international, Vol. 28, No. 5, 01.12.1992, p. 805-811.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Spectroscopic Evidence for the Existence of an Obligate Pre-Fibrillar Oligonomer during Glucagon Fibrillation. / Christensen, P. A.; Pedersen, J. S.; Christiansen, G.; Otzen, Daniel.

    In: F E B S Letters, No. 582, 2008, p. 1341-1345.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Stability and Folding of Endoglucanase I (CEL7B) from Humicoia Insolens. / Otzen, Daniel; Schülein, Martin.

    In: Biocatalysis and Biotransformation, Vol. 19, No. 42130, 01.01.2001, p. 469-487.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Stability and structure of the membrane protein transporter Ffh is modulated by substrates and lipids. / Reinau, Marika Ejby; Otzen, Daniel.

    In: Archives of Biochemistry and Biophysics, Vol. 492, 2009, p. 48-53.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Stabilization of the Ribosomal Protein S6 by Trehalose is Counterbalanced by the Formation of a Putative Off-pathway Species. / Chen, LuYang; Cabrita, Gonçalo J.M.; Otzen, Daniel; Melo, Eduardo Pinho.

    In: Journal of Molecular Biology, Vol. 351, 2005, p. 402-416.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Stabilizing vitamin D3 using the molten globule state of α-lactalbumin. / Pedersen, Jannik Nedergaard; Sørensen, Henrik V; Otzen, Daniel E.

    In: Journal of Dairy Science, Vol. 101, No. 3, 03.2018, p. 1817–1826.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  60. Published

    Stable intermediates determine proteins' primary unfolding sites in the presence of surfactants. / Hansen, Jonas Høeg; Petersen, Steen Vang; Andersen, Kell Kleiner; Enghild, Jan J; Damhus, Ture; Otzen, Daniel.

    In: Biopolymers, Vol. 91, No. 3, 2009, p. 221-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Stop-and-go kinetics in amyloid fibrillation. / Ferkinghoff-Borg, Jesper; Fonslet, Jesper; Andersen, Christian Beyschau; Krishna, Sandeep; Pigolotti, Simone; Yagi, Hisashi; Goto, Yuji; Otzen, Daniel; Jensen, Mogens H.

    In: Physical Review E. Statistical, Nonlinear, and Soft Matter Physics, Vol. 82, No. 1 Pt 1, 01.07.2010, p. 010901.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    Strategies to increase the reproducibility of protein fibrillization in plate reader assays. / Giehm, Lise; Otzen, Daniel E.

    In: Analytical Biochemistry, Vol. 400, No. 2, 15.05.2010, p. 270-81.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Strategies to increase the reproducibility of α-synuclein fibrillation in plate reader assays. / Giehm, Lise; Otzen, Daniel.

    In: Analytical Biochemistry, Vol. 406, No. 2, 15.11.2010, p. 270-281.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. Published

    Strong interactions with polyethylenimine-coated human serum albumin nanoparticles (PEI-HSA NPs) alter α-synuclein conformation and aggregation kinetics. / Mohammad-Beigi, Hossein; Shojaosadati, Seyed Abbas; Marvian, Amir Tayaranian; Pedersen, Jannik Nedergaard; Klausen, Lasse Hyldgaard; Christiansen, Gunna; Pedersen, Jan Skov; Dong, Mingdong; Morshedi, Dina; Otzen, Daniel E.

    In: Nanoscale, Vol. 7, 09.11.2015, p. 19627-19640.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    Structural Factors Contributing to the Hydrophobic Effect : The Partly Exposed Hydrophobic Minicore in Chymotrypsin Inhibitor. / Otzen, Daniel E.; Rheinnecker, Michael; Fersht, Alan R.

    In: Biochemistry, Vol. 34, No. 40, 01.01.1995, p. 13051-13058.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    Structural background of cyclodextrin-protein interactions. / Aachmann, F. L.; Otzen, D. E.; Larsen, K. L.; Wimmer, R.

    In: Protein Engineering, Vol. 16, No. 12, 01.12.2003, p. 905-912.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    Structural basis for cyclodextrins' suppression of human growth hormone aggregation. / Otzen, Daniel Erik; Knudsen, Benjamin Raerup; Aachmann, Finn; Larsen, Kim Lambertsen; Wimmer, Reinhard.

    In: Protein Science, Vol. 11, No. 7, 02.07.2002, p. 1779-1787.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    Structural changes in the transition state of protein folding : Alternative interpretations of curved chevron plots. / Otzen, Daniel E.; Kristensen, Ole; Proctor, Mark; Oliveberg, Mikael.

    In: Biochemistry, Vol. 38, No. 20, 18.05.1999, p. 6499-6511.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Structure of a Functional Amyloid Protein Subunit Computed Using Sequence Variation. / Tian, Pengfei; Boomsma, Wouter; Wang, Yong; Otzen, Daniel; Jensen, Mogens H; Lindorff-Larsen, Kresten.

    In: Journal of the American Chemical Society, Vol. 137, No. 1, 2015, p. 22-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Structure of the transition state for folding of a protein derived from experiment and simulation. / Daggett, Valerie; Li, Aijun; Itzhaki, Laura S.; Otzen, Daniel E.; Fersht, Alan R.

    In: Journal of Molecular Biology, Vol. 257, No. 2, 29.03.1996, p. 430-440.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  71. Published

    Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding. / Otzen, Daniel E.; Itzhaki, Laura S.; Elmasry, Nadia F.; Jackson, Sophie E.; Fersht, Alan R.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 22, 25.10.1994, p. 10422-10425.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. Published

    Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin. / Hjorth, Christian Fogt; Norrman, Mathias; Wahlund, Per-Olof; Benie, Andrew J.; Petersen, Bent O.; Jessen, Christian M; Pedersen, Thomas Å.; Vestergaard, Kirsten; Steensgaard, Dorte B; Pedersen, Jan Skov; Naver, Helle; Hubálek, František; Poulsen, Christian; Otzen, Daniel.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 4, 2016, p. 1376-1386.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. Published

    Sucrose prevents protein fibrillation through compaction of the tertiary structure but hardly affects the secondary structure. / Estrela, Nídia; Franquelim, Henri G; Lopes, Carlos; Tavares, Evandro; Macedo, Joana A; Christiansen, Gunna; Otzen, Daniel E; Melo, Eduardo P.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 83, No. 11, 11.2015, p. 2039-2051.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Sulfates Dramatically Stabilize a Salt-Dependent Type of Glucagon Fibrils. / Pedersen, Jesper Søndergaard; Flink, James M.; Dikov, Dantcho; Otzen, Daniel.

    In: Biophysical Journal, Vol. 90, No. 11, 2006, p. 4181-4194.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Surfactant protein SP-B strongly modifies surface collapse of phospholipid vesicles: Insights from a quartz crystal microbalance with dissipation. / Cabré, Elisa; Malmström, Jenny; Sutherland, Duncan; Perez-Gil, Jesus; Otzen, Daniel.

    In: Biophysical Journal, Vol. 97, No. 3, 2009, p. 768-76.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    Surfactants and alcohols as inducers of protein amyloid: aggregation chaperones or membrane simulators? / Otzen, Daniel.

    In: Lipids and membranes in amyloid diseases, 2010.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Synergistic behavior of sodiumdodecylsulfate and 1,2-diheptanoyl-sn- glycero-3-phosphocholine in an aqueous medium : Interfacial and bulk behavior. / Sehgal, Pankaj; Doe, Hidekazu; Sharma, Manu; Otzen, Daniel E.

    In: Colloid and Polymer Science, Vol. 283, No. 11, 01.08.2005, p. 1219-1225.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Synthesis of a Ketomethylene Isostere of the Fibrillating Peptide SNNFGAILSS. / Mittag, Tina; Nielsen, Niels Christian; Otzen, Daniel; Skrydstrup, Troels.

    In: Journal of Organic Chemistry, Vol. 74, 09.09.2009, p. 7955-7957.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  79. Published

    Tailoring thermal treatment to form liprotide complexes between oleic acid and different proteins. / Sørensen, Henrik V; Pedersen, Jannik N; Pedersen, Jan Skov; Otzen, Daniel Erik.

    In: BBA Proteins and Proteomics, Vol. 1865, No. 6, 06.2017, p. 682–693.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  80. Published

    ThT 101 : a primer on the use of thioflavin T to investigate amyloid formation. / Malmos, Kirsten; Blancas-Mejia, Luis M; Weber, Benedikt; Buchner, Johannes; Ramirez-Alvarado, Marina; Naiki, Hironobu; Otzen, Daniel.

    In: Amyloid: the Journal of Protein Folding Disorders, Vol. 24, No. 1, 04.2017, p. 1-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    The Antimicrobial Mechanism of Action of Epsilon-Poly-L-Lysine. / Hyldgaard, Morten; Mygind, Tina; Vad, Brian S; Stenvang, Marcel; Otzen, Daniel; Meyer, Rikke L.

    In: Applied and Environmental Microbiology, Vol. 80, No. 24, 12.2014, p. 7758-7770 .

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  82. Published

    The Changing Face of Aging : Highly Sulfated Glycosaminoglycans Induce Amyloid Formation in a Lattice Corneal Dystrophy Model Protein. / Malmos, Kirsten G; Stenvang, Marcel; Sahin, Cagla; Christiansen, Gunna; Otzen, Daniel E.

    In: Journal of Molecular Biology, Vol. 429, No. 18, 01.09.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    The Importance of Being Capped : Terminal Capping of an Amyloidogenic Peptide Affects Fibrillation Propensity and Fibril Morphology. / Andreasen, Maria; Skeby, Katrine Kirkeby; Zhang, Shuai; Nielsen, Erik Holm; Klausen, Lasse Hyldgaard; Frahm, Heidi; Christiansen, Gunna; Skrydstrup, Troels; Dong, Mingdong; Schiøtt, Birgit; Otzen, Daniel.

    In: Biochemistry, Vol. 53, No. 44, 21.10.2014, p. 6968-6980.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    The Major Allergen from Birch Tree Pollen, Bet v 1, Binds and Permeabilizes Membranes. / Morgensen, JE; Ferreras, M; Wimmer, R; Petersen, Steen Vang; Enghild, Jan J.; Otzen, Daniel.

    In: Biochemistry, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. Published

    The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes. / Lorenzen, Nikolai; Lemminger, Lasse; Pedersen, Jannik Nedergaard; Nielsen, Søren Bang; Otzen, Daniel.

    In: FEBS Letters, Vol. 588, No. 3, 31.01.2014, p. 497-502.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. Published

    The Sheaths of Methanospirillum Are Made of a New Type of Amyloid Protein. / Christensen, Line Friis Bakmann; Hansen, Lonnie Maria; Finster, Kai; Christiansen, Gunna; Nielsen, Per Halkjaer; Otzen, Daniel Erik; Dueholm, Morten Simonsen.

    In: Frontiers in Microbiology, Vol. 9, 2729, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    The Tubular Sheaths Encasing Methanosaeta thermophila Filaments are Functional Amyloids. / Dueholm, Morten S; Larsen, Poul; Finster, Kai; Stenvang, Marcel R; Christiansen, Gunna; Vad, Brian S; Bøggild, Andreas; Otzen, Daniel E; Halkjær Nielsen, Per.

    In: Journal of Biological Chemistry, Vol. 290, 24.06.2015, p. 20590-26600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    The Use of Liprotides To Stabilize and Transport Hydrophobic Molecules. / Pedersen, Jannik N; Pedersen, Jan S; Otzen, Daniel E.

    In: Biochemistry, Vol. 54, No. 31, 28.07.2015, p. 4815-4823.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. Published

    The Use of Surfactants to Solubilise a Glucagon Analogue. / Madsen, Jens Kvist; Giehm, Lise; Otzen, Daniel E.

    In: Pharmaceutical Research, Vol. 35, No. 12, 235, 12.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  90. Published

    The anionic biosurfactant rhamnolipid does not denature industrial enzymes. / Madsen, Jens; Pihl, Rasmus; Møller, Anders H; Tranberg Madsen, Anne; Otzen, Daniel; Andersen, Kell K.

    In: Frontiers in Microbiology, Vol. 6, 292, 17.04.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  91. Published

    The compact and biologically relevant structure of inter-α-inhibitor is maintained by the chondroitin sulfate chain and divalent cations. / Scavenius, Carsten; Nikolajsen, Camilla Lund; Stenvang, Marcel; Thøgersen, Ida; Wyrozemski, Lukasz; Wisniewski, Hans-Georg; Otzen, Daniel E; Sanggaard, Kristian W; Enghild, Jan J.

    In: Journal of Biological Chemistry, Vol. 291, No. 9, 26.02.2016, p. 4658-4670.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. Published

    The diversity of FtsY-lipid interactions. / Reinau, M E; Thøgersen, I B; Enghild, J J; Nielsen, K L; Otzen, D E.

    In: Biopolymers, Vol. 93, No. 7, 01.07.2010, p. 595-606.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  93. Published

    The effect of osmolytes on protein fibrillation. / Macchi, Francesca; Eisenkolb, Maike; Kiefer, Hans; Otzen, Daniel.

    In: International Journal of Molecular Sciences (Online), Vol. 13, No. 3, 21.03.2012, p. 3801-3819.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  94. Published

    The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth. / van Gils, Juami Hermine Mariama; van Dijk, Erik; Peduzzo, Alessia; Hofmann, Alexander; Vettore, Nicola; Schützmann, Marie P; Groth, Georg; Mouhib, Halima; Otzen, Daniel E; Buell, Alexander K; Abeln, Sanne.

    In: PLOS Computational Biology, Vol. 16, No. 5, e1007767, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    The influence of vesicle composition and size on a-synuclein structure and stability. / Kjær, Lars; Giehm, Lise; Heimburg, Thomas Rainer; Otzen, Daniel.

    In: Biophysical Journal, Vol. 96, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  96. Published

    The interaction of equine lysozyme:oleic acid complexes with lipid membranes suggests a cargo off-loading mechanism. / Nielsen, Søren Bang; Wilhelm, Kristina; Vad, Brian; Schleucher, Jürgen; Morozova-Roche, Ludmilla A; Otzen, Daniel.

    In: Journal of Molecular Biology, Vol. 398, No. 2, 2010, p. 351-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  97. Published

    The interactome of stabilized α-synuclein oligomers and neuronal proteins. / van Diggelen, Femke; Frank, Signe Andrea; Somavarapu, Arun Kumar; Scavenius, Carsten; Apetri, Mihaela M; Nielsen, Janni; Tepper, Armand W J W; Enghild, Jan J; Otzen, Daniel E.

    In: The FEBS Journal, Vol. 287, No. 10, 2020, p. 2037-2054.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. Published

    The length distribution of frangible biofilaments. / Michaels, Thomas C T; Yde, Pernille; Willis, Julian C W; Jensen, Mogens H; Otzen, Daniel; Dobson, Christopher M; Buell, Alexander K; Knowles, Tuomas P J.

    In: Journal of Chemical Physics, Vol. 143, No. 16, 164901, 28.10.2015, p. 1-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands. / Mogensen, Jesper E.; Wimmer, Reinhard; Larsen, Jørgen N.; Spangfort, Michael D.; Otzen, Daniel E.

    In: Journal of Biological Chemistry, Vol. 277, No. 26, 28.06.2002, p. 23684-23692.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    The natural, peptaibolic peptide SPF-5506-A4 adopts a β-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores. / Frahm, Heidi; Hansen, Sara K; Vad, Brian S; Nielsen, Erik H; Nielsen, Jakob T; Vosegaard, Thomas; Skrydstrup, Troels; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1854, No. 8, 08.2015, p. 882-889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity. / Jarvela, Timothy S; Lam, Hoa A; Helwig, Michael; Lorenzen, Nikolai; Otzen, Daniel E; McLean, Pamela J; Maidment, Nigel T; Lindberg, Iris.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 32, 25.07.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review