Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. 2013
  2. Published

    Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization. / Underhaug, Jarl; Koldsø, Heidi; Runager, Kasper; Nielsen, Jakob Toudahl; Sørensen, Charlotte S; Kristensen, Torsten; Otzen, Daniel; Karring, Henrik; Malmendal, Anders; Schiøtt, Birgit; Enghild, Jan J; Nielsen, Niels Christian.

    In: BBA General Subjects, Vol. 1834, No. 12, 12.10.2013, p. 2812–2822.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Quality control system response to stochastic growth of amyloid fibrils. / Pigolotti, Simone; Lizana, Ludvig; Otzen, Daniel; Sneppen, Kim.

    In: F E B S Letters, Vol. 587, No. 9, 02.05.2013, p. 1405-1410.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Folding of outer membrane proteins. / Otzen, Daniel; Andersen, Kell K.

    In: Archives of Biochemistry and Biophysics, Vol. 531, No. 1-2, 2013, p. 34-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Wildtype and A30P Mutant Alpha-Synuclein Form Different Fibril Structures. / Nielsen, Søren Bang; Macchi, Francesca; Raccosta, Samuele; Langkilde, Annette Eva; Giehm, Lise; Kyrsting, Anders; Svane, Anna Sigrid Pii; Manno, Mauro; Christiansen, Gunna; Nielsen, Niels Christian; Oddershede, Lene; Vestergaard, Bente; Otzen, Daniel.

    In: P L o S One, Vol. 8, No. 7, e67713, 2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. / Helwig, Michael; Hoshino, Akino; Berridge, Casey; Lee, Sang-Nam; Lorenzen, Nikolai; Otzen, Daniel; Eriksen, Jason; Lindberg, Iris.

    In: Journal of Biological Chemistry, Vol. 288, No. 2, 11.01.2013, p. 1114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Evolutionary Insight into the Functional Amyloids of the Pseudomonads. / Dueholm, Morten Simonsen; Otzen, Daniel; Nielsen, Per Halkjær.

    In: PLOS ONE, Vol. 8, No. 10, e76630, 07.10.2013, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation. / Dueholm, Morten S; Søndergaard, Mads; Nilsson, Martin; Christiansen, Gunna; Stensballe, Allan; Overgaard, Michael T; Givskov, Michael Christian; Tolker-Nielsen, Tim; Otzen, Daniel; Nielsen, Per H.

    In: MicrobiologyOpen, Vol. 2, No. 3, 06.2013, p. 365-382.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Off-pathway aggregation can inhibit fibrillation at high protein concentrations. / Deva, Taru; Lorenzen, Nikolai; Vad, Brian S; Petersen, Steen V; Thørgersen, Ida; Enghild, Jan J; Kristensen, Torsten; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 3, 03.2013, p. 677-687.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. / Cohen, Samuel I A; Linse, Sara; Luheshi, Leila M; Hellstrand, Erik; White, Duncan A; Rajah, Luke; Otzen, Daniel; Vendruscolo, Michele; Dobson, Christopher M; Knowles, Tuomas P J.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 24, 23.05.2013, p. 9758-9763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Protein:fatty acid complexes : Biochemistry, biophysics and function. / Brinkmann, Christel Rothe; Thiel, Steffen; Otzen, Daniel.

    In: F E B S Journal, Vol. 280, No. 8, 04.2013, p. 1733–1749.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Novicidin's membrane permeabilizing activity is driven by membrane partitioning but not by helicity : A biophysical study of the impact of lipid charge and cholesterol. / Balakrishnan, Vijay S; Vad, Brian S; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 6, 02.04.2013, p. 996-1002.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Formation of dynamic soluble surfactant-induced amyloid β peptide aggregation intermediates. / Abelein, Axel; Kaspersen, Jørn Døvling; Nielsen, Søren Bang; Jensen, Grethe Vestergaard; Christiansen, Gunna; Pedersen, Jan Skov; Danielsson, Jens Albert; Otzen, Daniel; Gräslund, Astrid.

    In: Journal of Biological Chemistry, Vol. 288, 09.08.2013, p. 23518-23528.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2012
  15. Published

    A Ser residue influences the structure and stability of a Pro-kinked transmembrane helix dimer. / Weber, Mathias; Tome, Lydia; Otzen, Daniel; Schneider, Dirk.

    In: BBA General Subjects, Vol. 1818, No. 9, 2012, p. 2103-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    PP3 forms stable tetrameric structures through hydrophobic interactions via the C-terminal amphipathic helix and undergoes reversible thermal dissociation and denaturation. / Pedersen, Lise R L; Nielsen, Søren Bang; Hansted, Jon Gade; Petersen, Torben E; Otzen, Daniel E; Sørensen, Esben S.

    In: F E B S Journal, Vol. 279, No. 2, 2012, p. 336-47.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Proteolytic activation of proteose peptone component 3 by release of a C-terminal peptide with antibacterial properties. / Pedersen, Lise Refstrup Linnebjerg; Hansted, J.G.; Nielsen, Søren Bang; Petersen, T.E.; Sørensen, U.S.; Otzen, D.; Sørensen, E.S.

    In: Journal of Dairy Science, Vol. 95, No. 6, 01.06.2012, p. 2819-2829.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition. / Otzen, Daniel; Blans, Kristine; Wang, Huabing; Gilbert, Gary E; Rasmussen, Jan T.

    In: BBA General Subjects, Vol. 1818, No. 4, 04.2012, p. 1019-1027.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    N for AsN - O for StrOcture? A strand-loop-strand motif for prokaryotic O-glycosylation. / Otzen, Daniel.

    In: Molecular Oral Microbiology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Eurocin, a new fungal defensin : structure, lipid binding and its mode of action. / Oeemig, Jesper S; Lynggaard, Carina; Knudsen, Daniel; Hansen, Frederik T; Noergaard, Kent D; Schneider, Tanja; Vad, Brian S; Sandvang, Dorthe; Nielsen, Line; Neve, Soeren; Kristensen, Hans-Henrik; Sahl, Hans-Georg; Otzen, Daniel; Wimmer, Reinhard.

    In: Journal of Biological Chemistry, Vol. 7, 07.12.2012, p. 42361-42372.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Multiple Roles of Heparin in the Aggregation of p25α. / Nielsen, Søren Bang; Yde, Pernille; Giehm, Lise; Sundbye, Sabrina; Christiansen, Gunna; Matthiesen, Joachim; Jensen, Mogens Høgh; Jensen, Poul Henning; Otzen, Daniel E.

    In: Journal of Molecular Biology, 2012.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    The effect of osmolytes on protein fibrillation. / Macchi, Francesca; Eisenkolb, Maike; Kiefer, Hans; Otzen, Daniel.

    In: International Journal of Molecular Sciences (Online), Vol. 13, No. 3, 21.03.2012, p. 3801-3819.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Role of elongation and secondary pathways in S6 amyloid fibril growth. / Lorenzen, N.; Cohen, S.I.A.; Nielsen, Søren Bang; Herling, T.W.; Christiansen, G.; Dobson, C.M.; T. P. Knowles, Tuomas; Otzen, D.

    In: Biophysical Journal, Vol. 102, No. 9, 02.05.2012, p. 2167-2175.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Scanning Tunneling Microscopy Reveals Single-Molecule Insights into the Self-Assembly of Amyloid Fibrils. / Kalashnyk, Nataliya; Nielsen, Jakob T; Nielsen, Erik H; Skrydstrup, Troels; Otzen, Daniel; Lægsgaard, Erik; Wang, Chen; Besenbacher, Flemming; Nielsen, Niels Christian; Linderoth, Trolle R.

    In: A C S Nano, 2012, p. 6882-6889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Scanning tunneling microscopy reveals single-molecule insights into the self-assembly of amyloid fibrils. / Kalashnyk, N.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T.R.; Nielsen, J.T.; Nielsen, Erik Holm Toustrup; Skrydstrup, T.; Nielsen, N.C.; Otzen, D.E.; Wang, C.

    In: A C S Nano, Vol. 6, No. 8, 28.08.2012, p. 6882-6889.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Cyclodextrin-Scaffolded Alamethicin with Remarkably Efficient Membrane Permeabilizing Properties and Membrane Current Conductance. / Hjørringgaard, Claudia Ulrich; Vad, Brian Stougaard; Matchkov, Vladimir; Nielsen, Søren Bang; Vosegaard, Thomas; Nielsen, Niels Christian; Otzen, Daniel; Skrydstrup, Troels.

    In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, Vol. 116, No. 26, 05.07.2012, p. 7652-7659.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Mapping out the multistage fibrillation of glucagon. / Ghodke, Shirin; Nielsen, Søren B; Christiansen, Gunna; Hjuler, Hans Aage; Flink, James; Otzen, Daniel; Nielsen, Søren Bang.

    In: F E B S Journal, Vol. 279, No. 5, 03.2012, p. 752-765.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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