Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. 2019
  2. Published

    In vitro and in silico assessment of the developability of a designed monoclonal antibody library. / Wolf Pérez, Adriana-Michelle; Sormanni, Pietro; Andersen, Jonathan Sonne; Sakhnini, Laila Ismail; Rodriguez-Leon, Ileana; Bjelke, Jais Rose; Gajhede, Annette Juhl; De Maria, Leonardo; Otzen, Daniel E; Vendruscolo, Michele; Lorenzen, Nikolai.

    In: mAbs, Vol. 11, No. 2, 2019, p. 388-400.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation. / Rasmussen, Casper B.; Christiansen, Gunna; Vad, Brian S.; Lynggaard, Carina; Enghild, Jan J.; Andreasen, Maria; Otzen, Daniel.

    In: Protein Science, Vol. 28, No. 3, 01.03.2019, p. 633-642.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Molecular dynamics study of ACBP denaturation in alkyl sulfates demonstrates possible pathways of unfolding through fused surfactant clusters. / Poghosyan, Armen H.; Schafer, Nicholas; Lyngsø, Jeppe; Shahinyan, Aram A.; Pedersen, Jan Skov; Otzen, Daniel.

    In: Protein Engineering, Design and Selection, Vol. 32, No. 4, gzz037, 04.2019, p. 175-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures. / Pedersen, Jannik Nedergaard; Jiang, Zhiping; Christiansen, Gunna; Lee, Jennifer C; Pedersen, Jan Skov; Otzen, Daniel E.

    In: Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1867, No. 5, 2019, p. 519-528.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Functional Amyloids. / Otzen, Daniel; Riek, Roland.

    In: Cold Spring Harbor Perspectives in Biology, Vol. 11, No. 12, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Alterations in Blood Monocyte Functions in Parkinson's Disease. / Nissen, Sara Konstantin; Shrivastava, Kalpana; Schulte, Claudia; Otzen, Daniel Erik; Goldeck, David; Berg, Daniela; Møller, Holger Jon; Maetzler, Walter; Romero-Ramos, Marina.

    In: Movement Disorders, Vol. 34, No. 11, 11.2019, p. 1711-1721.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Bacterial amphiphiles as amyloid inducers : Effect of Rhamnolipid and Lipopolysaccharide on FapC fibrillation. / Najarzadeh, Zahra; Pedersen, Jannik Nedergaard; Christiansen, Gunna; Shojaosadati, Seyed Abbas; Pedersen, Jan Skov; Otzen, Daniel E.

    In: B B A - Proteins and Proteomics, Vol. 1867, No. 11, 140263, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Plant polyphenols inhibit functional amyloid and biofilm formation in Pseudomonas strains by directing monomers to off-pathway oligomers. / Najarzadeh, Zahra; Mohammad-Beigi, Hossein; Pedersen, Jannik Nedergaard; Christiansen, Gunna; Sønderby, Thorbjørn Vincent; Shojaosadati, Seyed Abbas; Morshedi, Dina; Strømgaard, Kristian; Meisl, Georg; Sutherland, Duncan; Pedersen, Jan Skov; Otzen, Daniel.

    In: Biomolecules, Vol. 9, No. 11, 659, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants. / Mohammad-Beigi, Hossein; Kjær, Lars; Eskandari, Hoda; Aliakbari, Farhang; Christiansen, Gunna; Ruvo, Gianluca ; L. Ward, Jane ; Otzen, Daniel.

    In: Frontiers in Plant Science, Vol. 10, No. 148, 148, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein. / Mohammad-Beigi, Hossein; Hosseini, Atiyeh; Adeli, Mohsen; Ejtehadi, Mohammad Reza; Christiansen, Gunna; Sahin, Cagla; Tu, Zhaoxu; Tavakol, Mahdi; Dilmaghani-Marand, Arezou; Nabipour, Iraj; Farzadfar, Farshad; Otzen, Daniel Erik; Mahmoudi, Morteza; Hajipour, Mohammad Javad.

    In: ACS Nano, Vol. 13, No. 3, 2019, p. 3243-3256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. / Mohammad-Beigi, Hossein; Aliakbari, Farhang; Sahin, Cagla; Lomax, Charlotte; Tawfike, Ahmed; P. Schafer, Nicholas; Amiri-Nowdijeh, Alireza; Eskandari, Hoda; Møller, Ian Max; Hosseini-Mazinani, Mehdi; Christiansen, Gunna; Ward, Jane L; Morshedi, Dina; Otzen, Daniel.

    In: Journal of Biological Chemistry, Vol. 294, No. 11, 2019, p. 4215-4232.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures. / Juhl, Dennis Wilkens; Risør, Michael Wulff; Scavenius, Carsten; Rasmussen, Casper Bøjer; Otzen, Daniel; Nielsen, Niels Chr; Enghild, Jan J.

    In: Scientific Reports, Vol. 9, No. 1, 3863, 07.03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation. / Christensen, Line Friis Bakmann; Jensen, Kirstine Friis; Nielsen, Janni; Vad, Brian Stougaard; Christiansen, Gunna; Otzen, Daniel Erik.

    In: ACS Omega, Vol. 4, No. 2, 02.2019, p. 4029-4039.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Physical Determinants of Amyloid Assembly in Biofilm Formation. / Andreasen, Maria; Meisl, Georg; Taylor, Jonathan D; Michaels, Thomas C T; Levin, Aviad; Otzen, Daniel E; Chapman, Matthew R; Dobson, Christopher M; Matthews, Steve J; Knowles, Tuomas P J.

    In: mBio, Vol. 10, No. 1, e02279-18, 08.01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. 2018
  17. Published

    Early events in copper-ion catalyzed oxidation of α-synuclein. / Tiwari, Manish K; Leinisch, Fabian; Sahin, Cagla; Møller, Ian Max; Otzen, Daniel; Davies, Michael J; Bjerrum, Morten J.

    In: Free Radical Biology & Medicine, Vol. 121, 06.2018, p. 38-50.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Corneal dystrophy mutations drive pathogenesis by targeting TGFBIp stability and solubility in a latent amyloid-forming domain. / Stenvang, Marcel; Schafer, Nicholas P; Malmos, Kirsten Gade; Pérez, Adriana-Michelle Wolf; Niembro, Olatz; Sormanni, Pietro; Basaiawmoit, Rajiv Vaid; Christiansen, Gunna; Andreasen, Maria; Otzen, Daniel E.

    In: Journal of Molecular Biology, Vol. 430, No. 8, 13.04.2018, p. 1116-1140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    α-synucleins from animal species show low fibrillation propensities and weak oligomer membrane disruption. / Sahin, Cagla; Kjær, Lars; Christensen, Mette Solvang; Nedergaard Pedersen, Jannik; Christiansen, Gunna; Pérez, Adriana-Michelle Wolf; Moller, Ian Max; Enghild, Jan; Pedersen, Jan Skov; Larsen, Knud; Otzen, Daniel Erik.

    In: Biochemistry, Vol. 57, No. 34, 2018, p. 5145-5158.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Stabilizing vitamin D3 using the molten globule state of α-lactalbumin. / Pedersen, Jannik Nedergaard; Sørensen, Henrik V; Otzen, Daniel E.

    In: Journal of Dairy Science, Vol. 101, No. 3, 03.2018, p. 1817–1826.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Liprotides assist in folding of outer membrane proteins. / Nedergaard Pedersen, Jannik; Skov Pedersen, Jan; Otzen, Daniel E.

    In: Protein Science, Vol. 27, No. 2, 01.02.2018, p. 451-462.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Role of charge and hydrophobicity in liprotide formation : a molecular dynamics study with experimental constraints. / Nedergaard Pedersen, Jannik; Wilhelmus Johannes Maria Frederix, Pim; Skov Pedersen, Jan; Marrink, Siewert Jan; Otzen, Daniel.

    In: ChemBioChem, Vol. 19, No. 3, 02.02.2018, p. 263–271.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    The Use of Surfactants to Solubilise a Glucagon Analogue. / Madsen, Jens Kvist; Giehm, Lise; Otzen, Daniel E.

    In: Pharmaceutical Research, Vol. 35, No. 12, 235, 12.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State. / Kurnik, Martin; Sahin, Cagla; Andersen, Camilla Bertel; Lorenzen, Nikolai; Giehm, Lise; Mohammad-Beigi, Hossein; Jessen, Christian Moestrup; Pedersen, Jan Skov; Christiansen, Gunna; Petersen, Steen Vang; Staal, Roland; Krishnamurthy, Girija; Pitts, Keith; Reinhart, Peter H; Mulder, Frans A A; Mente, Scot; Hirst, Warren D; Otzen, Daniel E.

    In: Cell Chemical Biology, Vol. 25, No. 11, 15.11.2018, p. 1389-1402.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Can a Charged Surfactant Unfold an Uncharged Protein? / Højgaard, Casper; Sørensen, Henrik Vinther; Pedersen, Jan Skov; Winther, Jakob Rahr; Otzen, Daniel Erik.

    In: Biophysical Journal, Vol. 115, No. 11, 04.12.2018, p. 2081-2086.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Dynamic content exchange between liprotides. / Frislev, Henriette S; Jakobsen, Stine C L; Frank, Signe A; Otzen, Daniel E.

    In: Biophysical Chemistry, Vol. 233, 02.2018, p. 13-18.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Using Liprotides to Deliver Cholesterol to the Plasma Membrane. / Frislev, Henriette S.; Nielsen, Janni; Nylandsted, Jesper; Otzen, Daniel.

    In: Journal of Membrane Biology, Vol. 25, No. 4, 08.2018, p. 581-592.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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