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Daniel Otzen

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  1. 2023
  2. Published

    Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions. / Somavarapu, Arun Kumar; Kleijwegt, Giulia; Nagaraj, Madhu et al.

    In: Chemical Science, Vol. 14, No. 11, 03.2023, p. 3030-3047.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. Published

    FapA is an Intrinsically Disordered Chaperone for Pseudomonas Functional Amyloid FapC. / Rasmussen, Helena Ø; Kumar, Amit; Shin, Ben et al.

    In: Journal of Molecular Biology, Vol. 435, No. 2, 167878, 01.2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  4. Published

    The anti-platelet drug ticlopidine inhibits FapC fibrillation and biofilm production : Highlighting its antibiotic activity. / Pirhaghi, Mitra; Najarzadeh, Zahra; Moosavi-Movahedi, Faezeh et al.

    In: B B A - Proteins and Proteomics, Vol. 1871, No. 2, 140883, 02.2023, p. 140883.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  5. Published

    The impact of α-synuclein aggregates on blood-brain barrier integrity in the presence of neurovascular unit cells. / Hourfar, Hamdam; Aliakbari, Farhang; Aqdam, Shabboo Rahimi et al.

    In: International Journal of Biological Macromolecules, Vol. 229, 02.2023, p. 305-320.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  6. Published

    Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation. / Alijanvand, Saeid Hadi; Ladefoged, Lucy Kate; Zubrienė, Asta et al.

    In: International Journal of Biological Macromolecules, Vol. 227, 2023, p. 590-600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  7. 2022
  8. Published

    Functional Bacterial Amyloids : Understanding Fibrillation, Regulating Biofilm Fibril Formation and Organizing Surface Assemblies. / Sønderby, Thorbjørn Vincent; Najarzadeh, Zahra; Otzen, Daniel Erik.

    In: Molecules, Vol. 27, No. 13, 4080, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  9. Published

    How do surfactants unfold and refold proteins? / Otzen, Daniel E; Pedersen, Jannik Nedergaard; Rasmussen, Helena Østergaard et al.

    In: Advances in Colloid and Interface Science, Vol. 308, 102754, 10.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  10. Published

    Folding steps in the fibrillation of functional amyloid : denaturant sensitivity reveals common features in nucleation and elongation. / Sønderby, Thorbjørn V; Rasmussen, Helena Ø; Frank, Signe A et al.

    In: Journal of Molecular Biology, Vol. 434, No. 2, 167337, 01.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  11. Published

    Molecular-level insights into the surface-induced assembly of Functional Bacterial Amyloid. / Sønderby, Thorbjørn Vincent; Zou, Yimin; Wang, Pengyu et al.

    In: Biophysical Journal, Vol. 121, No. 18, 09.2022, p. 3422-3434.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  12. Published

    Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization. / Sahin, Cagla; Østerlund, Eva Christina; Österlund, Nicklas et al.

    In: Journal of the American Chemical Society, Vol. 144, No. 27, 07.2022, p. 11949-11954.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  13. Published

    Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein. / Reimer, Lasse; Haikal, Caroline; Gram, Hjalte et al.

    In: Scientific Reports, Vol. 12, 3737, 03.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  14. Published

    Induction, inhibition, and incorporation : Different roles for anionic and zwitterionic lysolipids in the fibrillation of the functional amyloid FapC. / Rasmussen, Helena Østergaard; Otzen, Daniel E; Pedersen, Jan Skov.

    In: The Journal of Biological Chemistry, Vol. 298, No. 2, 101569, 02.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  15. Published

    The changing face of SDS denaturation : Complexes of Thermomyces lanuginosus lipase with SDS at pH 4.0, 6.0 and 8.0. / Rasmussen, Helena Østergaard; Wollenberg, Daniel T Weltz; Wang, Huabing et al.

    In: Journal of Colloid and Interface Science, Vol. 614, 05.2022, p. 214-232.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  16. Published

    A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers. / Pirhaghi, Mitra; Frank, Signe Andrea; Alam, Parvez et al.

    In: Journal of Biological Chemistry, Vol. 298, No. 12, 102688, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  17. Published

    Functional amyloid in a lipid-like environment : a merry dance of many steps. / Otzen, Daniel E.

    In: Essays in Biochemistry, Vol. 66, No. 7, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  18. Published

    Characterization of exogenous αSN response genes and their relation to Parkinson's disease using network analyses. / Nayeri, Zahra; Aliakbari, Farhang; Afzali, Farzaneh et al.

    In: Frontiers in Pharmacology, Vol. 13, 966760, 2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. Published

    Interaction of membrane vesicles with the Pseudomonas functional amyloid protein FapC facilitates amyloid formation. / Najarzadeh, Zahra; Mohammad-Beigi, Hossein; Pedersen, Jannik Nedergaard et al.

    In: BBA advances, Vol. 2, 2022, p. 100055.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20. Published

    Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation. / Nagaraj, Madhu; Najarzadeh, Zahra; Pansieri, Jonathan et al.

    In: Chemical Science, Vol. 13, No. 2, 01.2022, p. 536-553.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. Published

    A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. / Mohammad-Beigi, Hossein; Zanganeh, Masumeh; Scavenius, Carsten et al.

    In: ACS Nano, Vol. 16, No. 1, 01.2022, p. 1102-1118.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  22. Published

    Uncovering the universality of self-replication in protein aggregation and its link to disease. / Meisl, Georg; Xu, Catherine K.; Taylor, Jonathan D. et al.

    In: Science Advances, Vol. 8, No. 32, eabn6831, 08.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  23. Published

    A Semester-Long Learning Path Teaching Computational Skills via Molecular Graphics in PyMOL. / Kjærgaard, Magnus; Rasmussen, Laura Skak; Vinther, Johan Nygaard et al.

    In: The Biophysicist, Vol. 3, No. 2, 12.2022, p. 106–114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  24. Published

    Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells. / He, Jianfei; Steffen, Jonas Hyld; Thulstrup, Peter Waaben et al.

    In: Scientific Reports, Vol. 12, No. 1, 22051, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  25. Published

    EGCG has Dual and Opposing Effects on the N-terminal Region of Self-associating α-synuclein Oligomers. / Grønnemose, Anne Louise; Østerlund, Eva Christina; Otzen, Daniel Erik et al.

    In: Journal of Molecular Biology, Vol. 434, No. 23, 167855, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  26. Published

    Glycation modulates alpha-synuclein fibrillization kinetics : a sweet spot for inhibition. / Farzadfard, Azad; König, Annekatrin; Petersen, Steen Vang et al.

    In: The Journal of Biological Chemistry, Vol. 298, No. 5, 101848, 05.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  27. Published

    The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization. / Farzadfard, Azad; Pedersen, Jannik Nedergaard; Meisl, Georg et al.

    In: Communications Biology, Vol. 5, No. 1, 123, 02.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

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