Aarhus University Seal / Aarhus Universitets segl

Daniel Otzen

  1. 2014
  2. Published

    Condenser : A statistical aggregation tool for multi-sample quantitative proteomic data from Matrix Science Mascot Distiller™. / Knudsen, Anders Dahl; Bennike, Tue; Kjeldal, Henrik; Birkelund, Svend; Otzen, Daniel; Stensballe, Allan.

    In: Journal of Proteomics, Vol. 103, 30.05.2014, p. 261-266.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation. / Kronqvist, Nina; Otikovs, Martins; Chmyrov, Volodymyr; Chen, Gefei; Andersson, Marlene; Nordling, Kerstin; Landreh, Michael; Sarr, Médoune; Jörnvall, Hans; Wennmalm, Stefan; Widengren, Jerker; Meng, Qing; Rising, Anna; Otzen, Daniel; Knight, Stefan D; Jaudzems, Kristaps; Johansson, Jan.

    In: Nature Communications, Vol. 5, 3254, 10.02.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Electrochemical Analysis of the Fibrillation of Parkinson's Disease α-synuclein. / Lopes, Paula; Dyrnesli, Hans; Lorenzen, Nikolai; Otzen, Daniel; Ferapontova, Elena.

    In: Analyst, Vol. 139, No. 4, 2014, p. 749-756.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro. / Lorenzen, Nikolai; Nielsen, Søren B.; Yoshimura, Yuichi; Vad, Brian S.; Andersen, Camilla Bertel; Betzer, Cristine; Kaspersen, Jørn D.; Christiansen, Gunna; Pedersen, Jan Skov; Jensen, Poul Henning; Mulder, Frans A A; Otzen, Daniel E.

    In: Journal of Biological Chemistry, Vol. 289, No. 31, 01.08.2014, p. 21299-21310.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Oligomers of α-synuclein : picking the culprit in the line-up. / Lorenzen, Nikolai; Otzen, Daniel.

    In: Essays in Biochemistry, Vol. 56, No. 1, 18.08.2014, p. 137-148.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes. / Lorenzen, Nikolai; Lemminger, Lasse; Pedersen, Jannik Nedergaard; Nielsen, Søren Bang; Otzen, Daniel.

    In: FEBS Letters, Vol. 588, No. 3, 31.01.2014, p. 497-502.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. / Lorenzen, Nikolai; Nielsen, Søren Bang; Buell, Alexander K. ; Kaspersen, Jørn Døvling; Arosio, Paolo; Vad, Brian Stougaard; Paslawski, Wojciech; Christiansen, Gunna; Valnickova Hansen, Zuzana; Andreasen, Maria; Enghild, Jan Johannes; Pedersen, Jan Skov; Dobson, Christopher M; Knowles, Tuomas P J; Otzen, Daniel.

    In: Journal of the American Chemical Society, Vol. 136, No. 10, 16.02.2014, p. 3859-3868.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Folding energetics and oligomerization of polytopic α-helical transmembrane proteins. / Neumann, Jennifer; Klein, Noreen; Otzen, Daniel; Schneider, Dirk.

    In: Archives of Biochemistry and Biophysics, Vol. 564, 15.12.2014, p. 281–296.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Membrane protein folding and stability. / Otzen, Daniel.

    In: Archives of Biochemistry and Biophysics, Vol. 564, 15.12.2014, p. 262-264.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Co-existence of Two Different α-Synuclein Oligomers with Different Core Structures Determined by Hydrogen/Deuterium Exchange Mass Spectrometry. / Paslawski, Wojciech; Mysling, Simon; Thomsen, Karen; Jørgensen, Thomas J D; Otzen, Daniel.

    In: Angewandte Chemie International Edition, Vol. 53, No. 29, 14.07.2014, p. 7560-7563.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    High stability and cooperative unfolding of cytotoxic α-synuclein oligomers. / Paslawski, Wojciech; Andreasen, Maria; Nielsen, Søren Bang; Lorenzen, Nikolai; Thomsen, Karen; Kaspersen, Jørn Døvling; Pedersen, Jan Skov; Otzen, Daniel.

    In: Biochemistry, Vol. 53, No. 39, 12.09.2014, p. 6252-6263.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene. / Poulsen, Ebbe Toftgaard; Runager, Kasper; Risør, Michael W; Dyrlund, Thomas Franck; Scavenius, Carsten; Karring, Henrik; Praetorius, Jeppe; Vorum, Henrik; Otzen, Daniel E; Klintworth, Gordon K; Enghild, Jan J.

    In: Proteomics - Clinical Applications, Vol. 8, No. 3-4, 04.2014, p. 168-177.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore. / Skals, Marianne; Bjaelde, Randi G; Reinholdt, Jesper; Poulsen, Knud; Vad, Brian S; Otzen, Daniel; Leipziger, Jens; Praetorius, Helle A.

    In: Journal of Biological Chemistry, Vol. 289, 04.07.2014, p. 19098-19109.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    The Molecular Basis for TGFBIp-Related Corneal Dystrophies. / Stenvang, Marcel Renè; Andreasen, Maria; Otzen, Daniel.

    Bio-nanoimaging : Protein Misfolding and Aggregation. Elsevier, 2014. p. 179-188.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  16. 2013
  17. Published

    Formation of dynamic soluble surfactant-induced amyloid β peptide aggregation intermediates. / Abelein, Axel; Kaspersen, Jørn Døvling; Nielsen, Søren Bang; Jensen, Grethe Vestergaard; Christiansen, Gunna; Pedersen, Jan Skov; Danielsson, Jens Albert; Otzen, Daniel; Gräslund, Astrid.

    In: Journal of Biological Chemistry, Vol. 288, 09.08.2013, p. 23518-23528.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Novicidin's membrane permeabilizing activity is driven by membrane partitioning but not by helicity : A biophysical study of the impact of lipid charge and cholesterol. / Balakrishnan, Vijay S; Vad, Brian S; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 6, 02.04.2013, p. 996-1002.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Protein:fatty acid complexes : Biochemistry, biophysics and function. / Brinkmann, Christel Rothe; Thiel, Steffen; Otzen, Daniel.

    In: F E B S Journal, Vol. 280, No. 8, 04.2013, p. 1733–1749.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. / Cohen, Samuel I A; Linse, Sara; Luheshi, Leila M; Hellstrand, Erik; White, Duncan A; Rajah, Luke; Otzen, Daniel; Vendruscolo, Michele; Dobson, Christopher M; Knowles, Tuomas P J.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 110, No. 24, 23.05.2013, p. 9758-9763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Off-pathway aggregation can inhibit fibrillation at high protein concentrations. / Deva, Taru; Lorenzen, Nikolai; Vad, Brian S; Petersen, Steen V; Thørgersen, Ida; Enghild, Jan J; Kristensen, Torsten; Otzen, Daniel.

    In: BBA General Subjects, Vol. 1834, No. 3, 03.2013, p. 677-687.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Evolutionary Insight into the Functional Amyloids of the Pseudomonads. / Dueholm, Morten Simonsen; Otzen, Daniel; Nielsen, Per Halkjær.

    In: PLOS ONE, Vol. 8, No. 10, e76630, 07.10.2013, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation. / Dueholm, Morten S; Søndergaard, Mads; Nilsson, Martin; Christiansen, Gunna; Stensballe, Allan; Overgaard, Michael T; Givskov, Michael Christian; Tolker-Nielsen, Tim; Otzen, Daniel; Nielsen, Per H.

    In: MicrobiologyOpen, Vol. 2, No. 3, 06.2013, p. 365-382.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Functional Amyloids in Bacteria. / Dueholm, Morten S.; Nielsen, Per Halkjaer; Chapman, Matthew; Otzen, Daniel.

    Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties. Wiley-VCH, 2013. p. 411-438.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  25. Published

    Fibrillar Polymorphism. / Fändrich, Marcus; Wulff, Melanie; Pedersen, Jesper Søndergaard; Otzen, Daniel.

    Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties. Wiley-VCH, 2013. p. 321-343.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  26. Published

    Experimental Approaches to Inducing Amyloid Aggregates. / Giehm, Lise; Otzen, Daniel.

    Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties. Wiley-VCH, 2013. p. 295-320.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  27. Published

    The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. / Helwig, Michael; Hoshino, Akino; Berridge, Casey; Lee, Sang-Nam; Lorenzen, Nikolai; Otzen, Daniel; Eriksen, Jason; Lindberg, Iris.

    In: Journal of Biological Chemistry, Vol. 288, No. 2, 11.01.2013, p. 1114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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