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Daniel Otzen

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  1. 2023
  2. Published
    Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions. / Somavarapu, Arun Kumar; Kleijwegt, Giulia; Nagaraj, Madhu et al.
    In: Chemical Science, Vol. 14, No. 11, 03.2023, p. 3030-3047.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. Published
    The anti-platelet drug ticlopidine inhibits FapC fibrillation and biofilm production: Highlighting its antibiotic activity. / Pirhaghi, Mitra; Najarzadeh, Zahra; Moosavi-Movahedi, Faezeh et al.
    In: B B A - Proteins and Proteomics, Vol. 1871, No. 2, 140883, 02.2023, p. 140883.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  4. Published
    The impact of α-synuclein aggregates on blood-brain barrier integrity in the presence of neurovascular unit cells. / Hourfar, Hamdam; Aliakbari, Farhang; Aqdam, Shabboo Rahimi et al.
    In: International Journal of Biological Macromolecules, Vol. 229, 02.2023, p. 305-320.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  5. Published
    FapA is an Intrinsically Disordered Chaperone for Pseudomonas Functional Amyloid FapC. / Rasmussen, Helena Ø; Kumar, Amit; Shin, Ben et al.
    In: Journal of Molecular Biology, Vol. 435, No. 2, 167878, 01.2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  6. Published
    Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation. / Alijanvand, Saeid Hadi; Ladefoged, Lucy Kate; Zubrienė, Asta et al.
    In: International Journal of Biological Macromolecules, Vol. 227, 2023, p. 590-600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  7. 2022
  8. Published
    A Semester-Long Learning Path Teaching Computational Skills via Molecular Graphics in PyMOL. / Kjærgaard, Magnus; Rasmussen, Laura Skak; Vinther, Johan Nygaard et al.
    In: The Biophysicist, Vol. 3, No. 2, 12.2022, p. 106–114.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  9. Published
    A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers. / Pirhaghi, Mitra; Frank, Signe Andrea; Alam, Parvez et al.
    In: Journal of Biological Chemistry, Vol. 298, No. 12, 102688, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. Published
    Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells. / He, Jianfei; Steffen, Jonas Hyld; Thulstrup, Peter Waaben et al.
    In: Scientific Reports, Vol. 12, No. 1, 22051, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  11. Published
    EGCG has Dual and Opposing Effects on the N-terminal Region of Self-associating α-synuclein Oligomers. / Grønnemose, Anne Louise; Østerlund, Eva Christina; Otzen, Daniel Erik et al.
    In: Journal of Molecular Biology, Vol. 434, No. 23, 167855, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  12. Published
    Functional amyloid in a lipid-like environment: a merry dance of many steps. / Otzen, Daniel E.
    In: Essays in Biochemistry, Vol. 66, No. 7, 12.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  13. Published
    How do surfactants unfold and refold proteins? / Otzen, Daniel E; Pedersen, Jannik Nedergaard; Rasmussen, Helena Østergaard et al.
    In: Advances in Colloid and Interface Science, Vol. 308, 102754, 10.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  14. Published
    Molecular-level insights into the surface-induced assembly of Functional Bacterial Amyloid. / Sønderby, Thorbjørn Vincent; Zou, Yimin; Wang, Pengyu et al.
    In: Biophysical Journal, Vol. 121, No. 18, 09.2022, p. 3422-3434.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  15. Published
    Uncovering the universality of self-replication in protein aggregation and its link to disease. / Meisl, Georg; Xu, Catherine K.; Taylor, Jonathan D. et al.
    In: Science Advances, Vol. 8, No. 32, eabn6831, 08.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  16. Published
    Functional Bacterial Amyloids: Understanding Fibrillation, Regulating Biofilm Fibril Formation and Organizing Surface Assemblies. / Sønderby, Thorbjørn Vincent; Najarzadeh, Zahra; Otzen, Daniel Erik.
    In: Molecules, Vol. 27, No. 13, 4080, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  17. Published
    Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization. / Sahin, Cagla; Østerlund, Eva Christina; Österlund, Nicklas et al.
    In: Journal of the American Chemical Society, Vol. 144, No. 27, 07.2022, p. 11949-11954.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  18. Published
    Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response. / Bisiak, Francesco; Chrenková, Adriana; Zhang, Sheng Da et al.
    In: Journal of Biological Chemistry, Vol. 298, No. 7, 102142, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. Published
    The optimal docking strength for reversibly tethered kinases. / Dyla, Mateusz; González Foutel, Nicolás S; Otzen, Daniel E et al.
    In: Proceedings of the National Academy of Sciences, Vol. 119, No. 25, e2203098119, 21.06.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20. Published
    Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition. / Farzadfard, Azad; König, Annekatrin; Petersen, Steen Vang et al.
    In: The Journal of Biological Chemistry, Vol. 298, No. 5, 101848, 05.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. Published
    The changing face of SDS denaturation: Complexes of Thermomyces lanuginosus lipase with SDS at pH 4.0, 6.0 and 8.0. / Rasmussen, Helena Østergaard; Wollenberg, Daniel T Weltz; Wang, Huabing et al.
    In: Journal of Colloid and Interface Science, Vol. 614, 05.2022, p. 214-232.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  22. Published
    Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein. / Reimer, Lasse; Haikal, Caroline; Gram, Hjalte et al.
    In: Scientific Reports, Vol. 12, 3737, 03.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  23. Published
    Bidirectional protein-protein interactions control liquid-liquid phase separation of PSD-95 and its interaction partners. / Christensen, Nikolaj Riis; Pedersen, Christian Parsbæk; Sereikaite, Vita et al.
    In: iScience, Vol. 25, No. 2, 103808, 02.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  24. Published
    Induction, inhibition, and incorporation: Different roles for anionic and zwitterionic lysolipids in the fibrillation of the functional amyloid FapC. / Rasmussen, Helena Østergaard; Otzen, Daniel E; Pedersen, Jan Skov.
    In: The Journal of Biological Chemistry, Vol. 298, No. 2, 101569, 02.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  25. Published
    The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization. / Farzadfard, Azad; Pedersen, Jannik Nedergaard; Meisl, Georg et al.
    In: Communications Biology, Vol. 5, No. 1, 123, 02.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  26. Published
    A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. / Mohammad-Beigi, Hossein; Zanganeh, Masumeh; Scavenius, Carsten et al.
    In: ACS Nano, Vol. 16, No. 1, 01.2022, p. 1102-1118.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  27. Published
    Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation. / Nagaraj, Madhu; Najarzadeh, Zahra; Pansieri, Jonathan et al.
    In: Chemical Science, Vol. 13, No. 2, 01.2022, p. 536-553.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  28. Published
    Folding steps in the fibrillation of functional amyloid: denaturant sensitivity reveals common features in nucleation and elongation. / Sønderby, Thorbjørn V; Rasmussen, Helena Ø; Frank, Signe A et al.
    In: Journal of Molecular Biology, Vol. 434, No. 2, 167337, 01.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  29. Published
    Characterization of exogenous αSN response genes and their relation to Parkinson's disease using network analyses. / Nayeri, Zahra; Aliakbari, Farhang; Afzali, Farzaneh et al.
    In: Frontiers in Pharmacology, Vol. 13, 966760, 2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  30. Published
    Interaction of membrane vesicles with the Pseudomonas functional amyloid protein FapC facilitates amyloid formation. / Najarzadeh, Zahra; Mohammad-Beigi, Hossein; Pedersen, Jannik Nedergaard et al.
    In: BBA advances, Vol. 2, 2022, p. 100055.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  31. Published
    Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers. / Alam, Parvez; Holst, Mikkel R; Lauritsen, Line et al.
    In: Fluids and Barriers of the CNS, Vol. 19, No. 1, 37, 2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  32. 2021
  33. Published
    A semi high-throughput method for real-time monitoring of curli producing Salmonella biofilms on air-solid interfaces. / Choong, Ferdinand X.; Huzell, Smilla; Rosenberg, Ming et al.
    In: Biofilm, Vol. 3, 100060, 12.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  34. Published
    Lipid Peroxidation Products HNE and ONE Promote and Stabilize Alpha-Synuclein Oligomers by Chemical Modifications. / Andersen, Camilla; Grønnemose, Anne Louise; Pedersen, Jannik N. et al.
    In: Biochemistry, Vol. 60, No. 47, 30.11.2021, p. 3644-3658.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  35. Published
    Adsorption of azo dyes by a novel bio-nanocomposite based on whey protein nanofibrils and nano-clay: Equilibrium isotherm and kinetic modeling. / Rahimi Aqdam, Shabboo; Otzen, Daniel E.; Mahmoodi, Niyaz Mohammad et al.
    In: Journal of Colloid and Interface Science, Vol. 602, 11.2021, p. 490-503.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  36. Published
    Membrane Structure of Aquaporin Observed with Combined Experimental and Theoretical Sum Frequency Generation Spectroscopy. / Schmüser, L; Trefz, M; Roeters, S J et al.
    In: Langmuir : the ACS journal of surfaces and colloids, Vol. 37, No. 45, 11.2021, p. 13452-13459.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  37. Published
    The bacterial amyloids phenol soluble modulins from staphylococcus aureus catalyze alpha-synuclein aggregation. / Haikal, Caroline; Pascual, Lei Ortigosa; Najarzadeh, Zahra et al.
    In: International Journal of Molecular Sciences , Vol. 22, No. 21, 11594, 11.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  38. Published
    AlphaFold: A Special Issue and a Special time for Protein Science. / Serpell, Louise C; Radford, Sheena E; Otzen, Daniel.
    In: Journal of Molecular Biology, Vol. 433, No. 20, 167231, 10.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Editorial › peer-review

  39. Published
    Microfluidics and the quantification of biomolecular interactions. / Otzen, Daniel E; Buell, Alexander K.; Jensen, Henrik.
    In: Current Opinion in Structural Biology, Vol. 70, 10.2021, p. 8-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  40. Published
    Cys-labelling kinetics of membrane protein GlpG: a role for specific SDS binding and micelle changes? / Otzen, Daniel E; Pedersen, Jannik Nedergaard; Somavarapu, Arun Kumar et al.
    In: Biophysical Journal, Vol. 120, No. 18, 09.2021, p. 4115-4128.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  41. Published
    Identification of amyloidogenic proteins in the microbiomes of a rat Parkinson's disease model and wild-type rats. / Christensen, Line Friis Bakmann; Alijanvand, Saeid Hadi; Burdukiewicz, Michał et al.
    In: Protein Science, Vol. 30, No. 9, 09.2021, p. 1854-1870.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  42. Published
    Heparin promotes fibrillation of most phenol-soluble modulin virulence peptides from Staphylococcus aureus. / Najarzadeh, Zahra; Zaman, Masihuz; Sereikaite, Vita et al.
    In: The Journal of Biological Chemistry, Vol. 297, No. 2, 08.2021, p. 100953.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  43. Published
    Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from Staphylococcus aureus. / Najarzadeh, Zahra; Nielsen, Janni; Farzadfard, Azad et al.
    In: ACS Omega, Vol. 6, No. 34, 08.2021, p. 21960-21970.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  44. Published
    Ubiquitin forms conventional decorated micelle structures with sodium dodecyl sulfate at saturation. / Mortensen, Henriette Gavlshøj; Otzen, Daniel Erik; Pedersen, Jan Skov.
    In: Journal of Colloid and Interface Science, Vol. 596, 08.2021, p. 233-244.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  45. Published
    Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential. / Ferreira, Nelson; Gram, Hjalte; Sorrentino, Zachary A et al.
    In: Acta Neuropathologica, Vol. 142, 07.2021, p. 87-115.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  46. Published
    Per-glycosylation of the Surface-Accessible Lysines: One-Pot Aqueous Route to Stabilized Proteins with Native Activity. / Walther, Raoul; Monge, Pere; Pedersen, Andreas et al.
    In: ChemBioChem, Vol. 22, No. 14, 07.2021, p. 2478-2485.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  47. Published
    A multimethod approach for analyzing FapC fibrillation and determining mass per length. / Rasmussen, Helena Østergaard; Otzen, Daniel E; Pedersen, Jan Skov.
    In: Biophysical Journal, Vol. 120, No. 11, 01.06.2021, p. 2262-2275.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  48. Published
    In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy. / Otzen, Daniel E.; Dueholm, Morten S.; Najarzadeh, Zahra et al.
    In: Small Methods, Vol. 5, No. 6, 2001002, 06.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  49. Published
    In-Silico Evidence for a Two Receptor Based Strategy of SARS-CoV-2. / Milanetti, Edoardo; Miotto, Mattia; Di Rienzo, Lorenzo et al.
    In: Frontiers in Molecular Biosciences, Vol. 8, 690655, 06.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  50. Published
    C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition. / Amodeo, Giuseppe Federico; Lee, Brenda Yasie; Krilyuk, Natalya et al.
    In: Scientific Reports, Vol. 11, No. 1, 8744, 04.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  51. Published
    Multiple Protective Roles of Nanoliposome-Incorporated Baicalein against Alpha-Synuclein Aggregates. / Aliakbari, Farhang; Mohammad-Beigi, Hossein; Abbasi, Shahsanam et al.
    In: Advanced Functional Materials, Vol. 31, No. 7, 2007765, 10.02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  52. Published
    A Triple Role for a Bilayer: Using Nanoliposomes to Cross and Protect Cellular Membranes. / Otzen, Daniel E; Morshedi, Dina; Mohammad-Beigi, Hossein et al.
    In: Journal of Membrane Biology, Vol. 254, No. 1, 02.2021, p. 29-39.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  53. Published
    Breakdown of supersaturation barrier links protein folding to amyloid formation. / Noji, Masahiro; Samejima, Tatsushi; Yamaguchi, Keiichi et al.
    In: Communications Biology, Vol. 4, No. 1, 120, 01.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  54. Published
    Molecular characteristics of porcine alpha-synuclein splicing variants. / Larsen, Knud; Bæk, Rikke; Sahin, Cagla et al.
    In: Biochimie, Vol. 180, 01.2021, p. 121-133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  55. Published
    Driving forces in amyloidosis: How does a light chain make a heavy heart? / Otzen, Daniel.
    In: The Journal of Biological Chemistry, Vol. 296, 100785, 2021, p. 100785.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  56. Published
    How epigallocatechin gallate binds and assembles oligomeric forms of human alpha-synuclein. / Andersen, Camilla B; Yoshimura, Yuichi; Nielsen, Janni et al.
    In: The Journal of Biological Chemistry, Vol. 296, 100788, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  57. 2020
  58. Published
    MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments. / Martins, Pedro M; Navarro, Susanna; Silva, Alexandra et al.
    In: Frontiers in Molecular Neuroscience, Vol. 13, 582488, 27.11.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  59. Published
    Phenol-Soluble Modulins Modulate Persister Cell Formation in Staphylococcus aureus. / Baldry, Mara; Bojer, Martin S; Najarzadeh, Zahra et al.
    In: Frontiers in Microbiology, Vol. 11, 573253, 11.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

  60. Published
    Structures and mechanisms of formation of liprotides. / Pedersen, Jannik Nedergaard; Frislev, Henriette Kristina Søster; Pedersen, Jan Skov et al.
    In: B B A - Proteins and Proteomics, Vol. 1868, No. 11, 140505, 11.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  61. Published
    Inhibitors of α-Synuclein fibrillation and oligomer toxicity in Rosa damascena: the all-pervading powers of flavonoids and phenolic glycosides. / Eskandari, Hoda; Ghanadian, Mustafa; Noleto-Dias, Clarice et al.
    In: ACS Chemical Neuroscience, Vol. 11, No. 19, 10.2020, p. 3161–3173.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  62. Published
    DIBMA nanodiscs keep α-synuclein folded. / Adão, Regina; Cruz, Pedro F; Vaz, Daniela C et al.
    In: Biochimica et Biophysica Acta - Biomembranes, Vol. 1862, No. 9, 183314, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  63. Published
    Peak Force Infrared - Kelvin Probe Force Microscopy. / Jakob, Devon S; Wang, Haomin; Zeng, Guanghong et al.
    In: Angewandte Chemie International Edition, Vol. 59, No. 37, 09.2020, p. 16083-16090.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  64. Published
    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin. / He, Jianfei; Becares, Eva Ramos; Thulstrup, Peter Waaben et al.
    In: Redox Biology, Vol. 36, 101631, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  65. Published
    Quantitating denaturation by formic acid: Imperfect repeats are essential to the stability of the functional amyloid protein FapC. / Christensen, Line Friis Bakmann; Nowak, Jan Stanislaw; Sønderby, Thorbjørn Vincent et al.
    In: The Journal of biological chemistry, Vol. 295, No. 37, 09.2020, p. 13031–13046.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  66. Published
    SDS-induced multi-stage unfolding of a small globular protein through different denatured states revealed by single-molecule fluorescence. / Krainer, Georg; Hartmann, Andreas; Bogatyr, Vadim et al.
    In: Chemical Science, Vol. 11, No. 34, 09.2020, p. 9141-9153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  67. Published
    Half a century of amyloids: past, present and future. / Ke, Pu Chun; Zhou, Ruhong; Serpell, Louise C et al.
    In: Chemical Society Reviews, Vol. 49, No. 15, 07.08.2020, p. 5473-5509.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  68. Published
    Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies. / Nielsen, Nadia Sukusu; Poulsen, Ebbe Toftgaard; Lukassen, Marie V et al.
    In: Progress in Retinal and Eye Research, Vol. 77, 100843, 07.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  69. Published
    Multi-Step Unfolding and Rearrangement of α-Lactalbumin by SDS Revealed by Stopped-Flow SAXS. / Jensen, Grethe Vestergaard; Pedersen, Jannik Nedergaard; Otzen, Daniel E. et al.
    In: Frontiers in Molecular Biosciences, Vol. 7, 125, 07.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  70. Published
    The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization. / Marvian, Amir Tayaranian; Aliakbari, Farhang; Mohammad-Beigi, Hossein et al.
    In: International Journal of Biological Macromolecules, Vol. 155, 07.2020, p. 543-550.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  71. Published
    Amyloid formation of α-synuclein based on the solubility- and supersaturation-dependent mechanism. / Sawada, Maya; Yamaguchi, Keiichi; Hirano, Miki et al.
    In: Langmuir, Vol. 36, No. 17, 05.2020, p. 4671-4681.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  72. Published
    Nanosilver Mitigates Biofilm Formation via FapC Amyloidosis Inhibition. / Huma, Zil-E; Javed, Ibrahim; Zhang, Zhenzhen et al.
    In: Small (Weinheim an der Bergstrasse, Germany), Vol. 16, No. 21, 1906674, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  73. Published
    The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth. / van Gils, Juami Hermine Mariama; van Dijk, Erik; Peduzzo, Alessia et al.
    In: PLOS Computational Biology, Vol. 16, No. 5, e1007767, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  74. Published
    Novel noscapine derivatives stabilize the native state of insulin against fibrillation. / Alijanvand, Saeid Hadi; Christensen, Mikkel Hovden; Christiansen, Gunna et al.
    In: International Journal of Biological Macromolecules, Vol. 147, 03.2020, p. 98-108.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  75. Published
    Unfolding and partial refolding of a cellulase from the SDS-denatured state: From β-sheet to α-helix and back. / Rasmussen, Helena Ø.; Enghild, Jan J; Otzen, Daniel E et al.
    In: B B A - General Subjects, Vol. 1864, No. 1, 129434, 01.2020, p. 129434 1-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  76. Published
    A complete picture of protein unfolding and refolding in surfactants. / Pedersen, Jannik Nedergaard; Lyngsø, Jeppe; Zinn, Thomas et al.
    In: Chemical Science, Vol. 11, No. 3, 2020, p. 699-712.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  77. Published
    Accelerated Amyloid Beta Pathogenesis by Bacterial Amyloid FapC. / Javed, Ibrahim; Zhang, Zhenzhen; Adamcik, Jozef et al.
    In: Advanced Science, Vol. 7, No. 18, 2001299, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  78. Published
    Amyloid fibril inhibition, acceleration, or fragmentation: Are nano-based approaches advance in the right direction? / Hajipour, Mohammad Javad; Mohammad-Beigi, Hossein; Nabipour, Iraj et al.
    In: Nano Today, Vol. 35, No. December, 100983, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  79. Published
    Predicted Loop Regions Promote Aggregation: A Study of Amyloidogenic Domains in the Functional Amyloid FapC. / Nagaraj, Madhu; Ahmed, Mumdooh; Lyngsø, Jeppe et al.
    In: Journal of Molecular Biology, Vol. 432, No. 7, 2020, p. 2232-2252.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  80. Published
    Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4. / Juul-Madsen, Kristian; Qvist, Per; Bendtsen, Kirstine L et al.
    In: Journal of Immunology, Vol. 204, No. 5, 2020, p. 1345-1361.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  81. Published
    The interactome of stabilized α-synuclein oligomers and neuronal proteins. / van Diggelen, Femke; Frank, Signe Andrea; Somavarapu, Arun Kumar et al.
    In: The FEBS Journal, Vol. 287, No. 10, 2020, p. 2037-2054.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  82. 2019
  83. Published
    Bacterial amphiphiles as amyloid inducers: Effect of Rhamnolipid and Lipopolysaccharide on FapC fibrillation. / Najarzadeh, Zahra; Pedersen, Jannik Nedergaard; Christiansen, Gunna et al.
    In: B B A - Proteins and Proteomics, Vol. 1867, No. 11, 140263, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  84. Published
    Plant polyphenols inhibit functional amyloid and biofilm formation in Pseudomonas strains by directing monomers to off-pathway oligomers. / Najarzadeh, Zahra; Mohammad-Beigi, Hossein; Pedersen, Jannik Nedergaard et al.
    In: Biomolecules, Vol. 9, No. 11, 659, 01.11.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  85. Published
    Alterations in Blood Monocyte Functions in Parkinson's Disease. / Nissen, Sara Konstantin; Shrivastava, Kalpana; Schulte, Claudia et al.
    In: Movement Disorders, Vol. 34, No. 11, 11.2019, p. 1711-1721.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  86. Published
    Interrelations between chemical changes in lactose-free UHT milk. / Knudsen, Lotte Juul; Nielsen, Søren Drud-Heydary; Rauh, Valentin et al.
    2019. Abstract from 16th Symposium on Milk Genomics and Human Health, Aarhus, Denmark.

    Research output: Contribution to conference › Conference abstract for conference › Research

  87. Published
    Interrelations between chemical changes in lactose-free UHT milk. / Knudsen, L. J.; Nielsen, S. D; Rauh, V. et al.
    2019. Abstract from Sandbjerg Seminar 2019, Sønderborg, Denmark.

    Research output: Contribution to conference › Conference abstract for conference › Research

  88. Published
    New Lactase Enzymes. / Knudsen, Lotte Juul; Nielsen, Søren Drud-Heydary; Rauh, Valentin et al.
    2019. Abstract from Sandbjerg Seminar 2019, Sønderborg, Denmark.

    Research output: Contribution to conference › Conference abstract for conference › Research

  89. Published
    α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities. / Alam, Parvez; Bousset, Luc; Melki, Ronald et al.
    In: Journal of Neurochemistry, Vol. 150, No. 5, 09.2019, p. 522-534.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  90. Published
    Molecular dynamics study of ACBP denaturation in alkyl sulfates demonstrates possible pathways of unfolding through fused surfactant clusters. / Poghosyan, Armen H.; Schafer, Nicholas; Lyngsø, Jeppe et al.
    In: Protein Engineering, Design and Selection, Vol. 32, No. 4, gzz037, 04.2019, p. 175-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  91. Published
    Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures. / Juhl, Dennis Wilkens; Risør, Michael Wulff; Scavenius, Carsten et al.
    In: Scientific Reports, Vol. 9, No. 1, 3863, 07.03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  92. Published
    Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation. / Rasmussen, Casper B.; Christiansen, Gunna; Vad, Brian S. et al.
    In: Protein Science, Vol. 28, No. 3, 01.03.2019, p. 633-642.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  93. Published
    Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation. / van Diggelen, Femke; Hrle, Dean; Apetri, Mihaela et al.
    In: PLOS ONE, Vol. 14, No. 3, 0213663, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  94. Published
    Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation. / Christensen, Line Friis Bakmann; Jensen, Kirstine Friis; Nielsen, Janni et al.
    In: ACS Omega, Vol. 4, No. 2, 02.2019, p. 4029-4039.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  95. Published
    Physical Determinants of Amyloid Assembly in Biofilm Formation. / Andreasen, Maria; Meisl, Georg; Taylor, Jonathan D et al.
    In: mBio, Vol. 10, No. 1, e02279-18, 08.01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  96. Published
    A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants. / Mohammad-Beigi, Hossein; Kjær, Lars; Eskandari, Hoda et al.
    In: Frontiers in Plant Science, Vol. 10, No. 148, 148, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  97. Published
    Bacterial Amyloids: Biogenesis and Biomaterials. / Christensen, Line Friis Bakmann; Schafer, Nicholas; Wolf-Perez, Adriana et al.
    Biological and Bio-inspired Nanomaterials. ed. / Sarah Perrett; Alexander K. Buell; Tuomas P.J. Knowles. Springer, 2019. p. 113-159 (Advances in Experimental Medicine and Biology, Vol. 1174).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  98. Published
    Functional Amyloids. / Otzen, Daniel; Riek, Roland.
    In: Cold Spring Harbor Perspectives in Biology, Vol. 11, No. 12, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  99. Published
    In vitro and in silico assessment of the developability of a designed monoclonal antibody library. / Wolf Pérez, Adriana-Michelle; Sormanni, Pietro; Andersen, Jonathan Sonne et al.
    In: mAbs, Vol. 11, No. 2, 2019, p. 388-400.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  100. Published
    Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures. / Pedersen, Jannik Nedergaard; Jiang, Zhiping; Christiansen, Gunna et al.
    In: Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1867, No. 5, 2019, p. 519-528.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  101. Published
    Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein. / Mohammad-Beigi, Hossein; Hosseini, Atiyeh; Adeli, Mohsen et al.
    In: ACS Nano, Vol. 13, No. 3, 2019, p. 3243-3256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  102. Published
    Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. / Mohammad-Beigi, Hossein; Aliakbari, Farhang; Sahin, Cagla et al.
    In: Journal of Biological Chemistry, Vol. 294, No. 11, 2019, p. 4215-4232.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  103. Published
    Quartz Crystal Microbalances as Tools for Probing Protein-Membrane Interactions. / Nielsen, Søren B; Otzen, Daniel E.
    Lipid-Protein Interactions: Methods and Protocols. ed. / Jörg H. Kleinschmidt. Vol. 2003 Springer, 2019. p. 31-52 (Methods in molecular biology (Clifton, N.J.)).

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  104. 2018
  105. Published
    Can a Charged Surfactant Unfold an Uncharged Protein? / Højgaard, Casper; Sørensen, Henrik Vinther; Pedersen, Jan Skov et al.
    In: Biophysical Journal, Vol. 115, No. 11, 04.12.2018, p. 2081-2086.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  106. Published
    The Use of Surfactants to Solubilise a Glucagon Analogue. / Madsen, Jens Kvist; Giehm, Lise; Otzen, Daniel E.
    In: Pharmaceutical Research, Vol. 35, No. 12, 235, 12.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

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