Cristine Betzer

  1. Journal article › Research › Peer-reviewed
  2. Published

    Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. / Betzer, Cristine; Lassen, Louise Berkhoudt; Olsen, Anders; Kofoed, Rikke Hahn; Reimer, Lasse; Gregersen, Emil; Zheng, Jin; Calì, Tito; Gai, Wei-Ping; Chen, Tong; Moeller, Arne; Brini, Marisa; Fu, Yuhong; Halliday, Glenda; Brudek, Tomasz; Aznar, Susana; Pakkenberg, Bente; Andersen, Jens Peter; Jensen, Poul Henning.

    In: EMBO Reports, Vol. 19, No. 5, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Characterizing the dynamics of alpha-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry. / Mysling, Simon; Betzer, Cristine; Jensen, Poul H; Jørgensen, Thomas J. D.

    In: Biochemistry, 05.11.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease. / Zondler, L; Miller-Fleming, L; Repici, M; Gonçalves, S; Tenreiro, S; Rosado-Ramos, R; Betzer, Cristine; Straatman, K R; Jensen, Poul Henning; Giorgini, F; Outeiro, T F.

    In: Cell Death & Disease, Vol. 5, 2014, p. e1350.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    ELISA method to detect α-synuclein oligomers in cell and animal models. / Lassen, Louise Berkhoudt; Gregersen, Emil; Isager, Anne Kathrine; Betzer, Cristine; Kofoed, Rikke Hahn; Jensen, Poul Henning.

    In: PLOS ONE, Vol. 13, No. 4, e0196056, 26.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro. / Lorenzen, Nikolai; Nielsen, Søren B.; Yoshimura, Yuichi; Vad, Brian S.; Andersen, Camilla Bertel; Betzer, Cristine; Kaspersen, Jørn D.; Christiansen, Gunna; Pedersen, Jan Skov; Jensen, Poul Henning; Mulder, Frans A A; Otzen, Daniel E.

    In: Journal of Biological Chemistry, Vol. 289, No. 31, 01.08.2014, p. 21299-21310.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Identification of Synaptosomal Proteins Binding to Monomeric and Oligomeric α-Synuclein. / Betzer, Cristine; Movius, A James; Shi, Min; Gai, Wei-Ping; Zhang, Jing; Jensen, Poul Henning.

    In: PLOS ONE, Vol. 10, No. 2, 02.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death. / Reimer, Lasse; Lund, Louise Buur; Betzer, Cristine; Zheng, Jin; Nielsen, Lærke Dalsgaard; Kofoed, Rikke Hahn; Lassen, Louise Berkhoudt; Bølcho, Ulrik; Paludan, Søren Riis; Fog, Karina; Jensen, Poul Henning.

    In: Neurobiology of Disease, 01.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation. / Kofoed, Rikke H; Betzer, Cristine; Lykke-Andersen, Søren; Molska, Ewa; Jensen, Poul H.

    In: Journal of Visualized Experiments, No. 135, 03.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production. / Kofoed, Rikke H; Zheng, Jin; Ferreira, Nelson; Lykke-Andersen, Søren; Salvi, Mauro; Betzer, Cristine; Reimer, Lasse; Jensen, Torben Heick; Fog, Karina; Jensen, Poul Henning.

    In: Neurobiology of Disease, Vol. 106, 17.10.2017, p. 49-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Protein partners of α-synuclein in Health and Disease. / Lassen, Louise Berkhoudt; Reimer, Lasse; Ferreira, Nelson; Betzer, Cristine; Jensen, Poul Henning.

    In: Brain Pathology, 03.03.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Stabilization of α-synuclein oligomers using formaldehyde. / Ruesink, Harm; Reimer, Lasse; Gregersen, Emil; Moeller, Arne; Betzer, Cristine; Jensen, Poul Henning.

    In: PLOS ONE, Vol. 14, No. 10, e0216764, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins. / Yatime, Laure; Betzer, Cristine; Jensen, Rasmus Kjeldsen; Mortensen, Sofia; Jensen, Poul Henning; Andersen, Gregers Rom.

    In: Structure, Vol. 24, No. 12, 06.12.2016, p. 2043-2052.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Review › Research › Peer-reviewed
  15. Published

    Commentary: Alpha-Synuclein Aggregates Cause Calcium Dysregulation by Activating Calcium Pump SERCA. / Betzer, Cristine; Jensen, Poul Henning.

    In: J. Neurology Neuromedicine, Vol. 3, No. 4, 06.07.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  16. Published

    Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies. / Betzer, Cristine; Jensen, Poul Henning.

    In: Frontiers in Neuroscience, Vol. 12, 819, 06.11.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  17. Book chapter › Education › Peer-reviewed
  18. Published

    The use of co-immunoprecipitation to study conformation-specific protein interactions of oligomeric α-synuclein aggregates. / Betzer, Cristine; Kofoed, Rikke Hahn; Jensen, Poul Henning.

    Neuromethods : co-immunoprecipitation methods for brain tissue. New York : Humana Press, 2019. p. 23-36 (Neuromethods, Vol. 144).

    Research output: Contribution to book/anthology/report/proceedingBook chapterEducationpeer-review

  19. Poster › Research › Not peer-reviewed
  20. Published

    REDUCED CYTOSOLIC CALCIUM CAUSED BY SERCA ACTIVATION IS AN EARLY AND PATHOGENIC EVENT IN THE CELLULAR STRESS CAUSED BY ALPHA-SYNUCLEIN OLIGOMERS. / Betzer, Cristine; Jensen, Poul Henning.

    2016. Poster session presented at FENS 2016, København, Denmark.

    Research output: Contribution to conferencePosterResearch

  21. Published

    Reduced cytosolic calcium caused by SERCA activation is an early and pathogenic event in the cellular stress caused by alpha-synuclein oligomers. / Betzer, Cristine; Jensen, Poul Henning.

    2015. Poster session presented at THE BRAIN PRIZE MEETING 2015 – “Imaging the Living Brain”, Middelfart, Denmark.

    Research output: Contribution to conferencePosterResearch

  22. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATE SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne; Olsen, Anders; Kofoed, Rikke Hahn; Zheng, Jin; Cali, Tito; Brini, Marisa; Gai, Wei-Ping; Andersen, Jens Peter; Jensen, Poul Henning.

    2017. Poster session presented at 20 years of alpha-synuclein in Parkinson's disease and related synucleinopathies, Greece.

    Research output: Contribution to conferencePosterResearch

  23. Published

    SOLUBLE AGGREGATES OF ALPHA-SYNUCLEIN ACTIVATES SERCA CAUSING CALCIUM DYSREGULATION. / Betzer, Cristine; Lassen, Louise Berkhoudt; Möller, Arne; Kofoed, Rikke Hahn; Zheng, Jin; Calì, Tito; Brini, Marisa; Gai, Wei Ping; Andersen, Jens Peter; Jensen, Poul Henning.

    2017. Poster session presented at AD/PD 2017 , Vienna, Austria.

    Research output: Contribution to conferencePosterResearch