Aarhus University Seal / Aarhus Universitets segl

Claus Oxvig

  1. 2004
  2. Published

    Pregnancy-associated plasma protein-A (PAPP-A) expression and insulin-like growth factor binding protein-4 protease activity in normal and malignant ovarian surface epithelial cells. / Kalli, K.R.; Chen, B.-K.; Bale, L.K.; Gernand, E.; Overgaard, M.T.; Oxvig, C.; Cliby, W.A.; Conover, C.A.

    In: International Journal of Cancer, Vol. 110, 2004, p. 633-640.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Pregnancy-associated plasma protein-A gene expression as a target of inflammatory cytokines. / Resch, Z.T.; Chen, B.K.; Bale, L.K.; Oxvig, C.; Overgaard, M.T.; nullC.A., Conover.

    In: Endocrinology, Vol. 145, 2004, p. 1124-1129.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Proteolytic degradation of IGF-binding protein (IGFBP)-2 in equine ovarian follicles: involvement of pregnancy-associated plasma protein-A (PAPP-A) and association with dominant but not subordinated follicles. / N., Gérard; Delpuech, T.; Oxvig, C.; Overgaard, M.T.; Monget, P.

    In: J. Endocrinol., Vol. 182, 2004, p. 457-466.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Screening for Down's syndrome in early and late first and second trimester using six maternal serum markers. / Christiansen, M.; Larsen, S.O.; Oxvig, C.; Qin, Q.-P.; Wagner, J.M.; Overgaard, M.T.; Gleich, G.J.; Sottrup-Jensen, L.; Nørgaard-Pedersen, B.

    In: Clin. Genet., Vol. 65, 2004, p. 11-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2003
  7. Published

    Complex of pregnancy-associated plasma protein-A and the proform of the eosiniphil major basic protein: Disulphide structure and carbohydrate attachment. / Overgaard, M.T.; Sørensen, E.S.; Stachowiak, D.; Boldt, H.B.; Kristensen, L.; Sottrup-Jensen, L.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 278, 2003, p. 2106-2117.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Localization and regulation of pregnancy-associated plasma protein a expressionin healing human skin. / Chen, B.K.; Leiferman, K.M.; Pittelkow, M.R.; Overgaard, M.T.; Oxvig, C.; Conover, C.A.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 88, 2003, p. 4465-4471.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Plasma C3d levels of young farmers correlate with respirable dust exposure levels during normal work in swine confinement buildings. / Hoffmann, Hans Jürgen; Iversen, Martin; Brandslund, Ivan; Sigsgaard, Torben; Omland, Øyvind; Oxvig, Claus; Holmskov, Uffe; Bjermer, Leif; Jensenius, Jens Christian; Dahl, Ronald.

    In: Annals of Agricultural and Environmental Medicine, Vol. 10, No. 1, 2003, p. 53-60.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and. / Monget, P.; Mazerbourg, S.; Delpuech, T.; Maurel, M.C.; Maniere, S.; Zapf, J.; Lalmanach, G.; Oxvig, C.; Overgaard, M.T.

    In: Biol. Reprod., Vol. 68, 2003, p. 77-86.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Transforming growth factor-beta regulation of the insulin-like growth factor binding protein-4 protease system in cultured human osteoblasts. / Ortiz, C.O.; Chen, B.K.; Bale, L.K.; Overgaard, M.T.; Oxvig, C.; Conover, C.A.

    In: J. Bone Miner. Res., Vol. 18, 2003, p. 1066-1072.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Unstable carotid plaque: biochemical and cellular marker of vulnerability. / Carbone, G.L.; Mauriello, A.; Christiansen, M.; Oxvig, C.; Spagnoli, L.G.; Schwartz, R.S.; Sangiorgi, G.

    In: Journal of Cardiovascular Medicine (Hagerstown), Vol. 4, 2003, p. 398-406.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. 2002
  14. Published

    Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats. / Laursen, Lisbeth S; Overgaard, Michael T; Weyer, Kathrin; Boldt, Henning B; Ebbesen, Peter; Christiansen, Michael; Sottrup-Jensen, Lars; Giudice, Linda C; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 277, No. 49, 06.12.2002, p. 47225-34.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity. / Søe, R.; Overgaard, M.T.; Thomsen, A.R.; Laursen, L.S.; Olsen, I.M.; Sottrup-Jensen, L.; Haaning, J.; Giudice, L.C.; Conover, C.A.; Oxvig, C.

    In: European Journal of Biochemistry, Vol. 269, 2002, p. 2247-2256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Identification and regulation of the IGFBP-4 protease and its physiologic inhibitor in human trophoblasts and endometrial stroma: Evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation. / Giudice, L.C.; Conover, C.A.; Bale, L.; Faessen, G.H.; Ilg, S.; Sun, I.; Suen, L.-F.; Irwin, J.C.; Christiansen, M.; Overgaard, Michael Toft; Oxvig, Claus.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 87, 2002, p. 2359-2366.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Molecular regulation of the insulin-like growth factor binding protein-4 protease system in human fibroblasts: Identification of a novel inducible inhibitor. / Chen, B.-K.; Overgaard, Michael Toft; Bale, L.K.; Resch, Z.T.; Christiansen, M; Oxvig, Claus; Oxvig, Claus; Conover, C.A.

    In: Endocrinology, Vol. 143, 2002, p. 1199-1205.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Pregnancy-associated plasma protein-A proteolytic activity is associated with the human placental trophoblast cell membrane. / Sun, I.Y.C; Overgaard, Michael Toft; Oxvig, Claus; Giudice, L.C.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 87, 2002, p. 5235-5240.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Substrate specificity of the metalloproteinase PAPP-A assessed by mutagenesis and analysis of synthetic peptides. Substrate residues distant from the scissile bond are critical for proteolysis. / Laursen, L.S.; Overgaard, M.T.; Nielsen, C.G.; Boldt, H.B.; Hopman, K.H.; Enghild, J.J.; Conover, C.A.; Sottrup-Jensen, L.; Giudice, L.C.; Oxvig, C.

    In: Biochem. J., Vol. 367, 2002, p. 31-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2001
  21. Published

    Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin. / Boldt, H B; Overgaard, M T; Laursen, L S; Weyer, K; Sottrup-Jensen, L; Oxvig, C; Weyer, Kathrin.

    In: Biochemical Journal, Vol. 358, No. Pt 2, 01.09.2001, p. 359-367.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty. / Bayes-Genis, A.; Schwartz, R.S.; Lewis, D.A.; Overgaard, M.T.; Christiansen, M.; Oxvig, C.; Ashai, K.; Holmes, D.R.Jr.; Conover, C.A.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 21, 2001, p. 335-341.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. / Bayes-Genis, A.; Conover, C.A.; Overgaard, M.T.; Bailey, K.R.; Christiansen, M.; Holmes, D.R.Jr.; Virmani, R.; Oxvig, C.; Schwartz, R.S.

    In: N. Engl. J. Med., Vol. 345, 2001, p. 1022-1029.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A. / Laursen, L.S.; Overgaard, M.T.; Soe, R.; Boldt, H.B.; Sottrup-Jensen, L.; Giudice, L.C.; Conover, C.A.; Oxvig, C.

    In: F E B S Letters, Vol. 504, 2001, p. 36-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Pregnancy-associated plasma protein-A (PAPP-A) in ovine, bovine, porcine, and equine ovarian follicles: involvement in IGF binding protein-4 proteolytic degradation and mRNA expression during follicular. / Mazerbourg, S.; Overgaard, M.T.; Oxvig, C.; Christiansen, M.; Conover, C.A.; Laurendeau, I.; Vidaud, M.; Tosser-Klopp, G.; Zapf, J.; Monget, P.

    In: Endocrinology, Vol. 142, 2001, p. 5243-5253.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  26. Published

    Pregnancy-associated plasma protein-A is the insulin-like growth factor binding protein-4 protease secreted by human ovarian granulosa cells and is a marker of dominant follicle selection and the Corpus. / Conover, C.A.; Faessen, G.F.; Ilg, K.E.; Chandrasekher, Y.A.; Christiansen, M.; Overgaard, M.T.; Oxvig, C.; Giudice, L.C.

    In: Endocrinology, Vol. 142, 2001, p. 2155-2158.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase. / Overgaard, M.T.; Boldt, H.B.; Laursen, L.S.; Sottrup-Jensen, L.; Conover, C.A.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 276, 2001, p. 21849-21853.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2000
  29. Published

    Expression of recombinant human pregnancy-associated plasma protein A and identification of the proform of eosinophil major basic protein as its physiological inhibitor. / Overgaard, M.T.; Haaning, J.; Boldt, H.B.; Olsen, I.M.; Laursen, L.S.; Christiansen, M.; Gleich, G.J.; Sottrup-Jensen, L.; Conover, C.A.; Oxvig, C.

    In: Journal of Biological Chemistry, Vol. 275, No. 40, 2000, p. 31128-31133.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Qualification and characterization of pregnancy-associated complex of angiotensiogen and the proform og eosinophil major basic protein serum and amniotic fluid. / Christiansen, M.; Jaliashvili, I.; Overgaard, M.T.; Ensinger, C.; Obrist, P.; Oxvig, C.

    In: Clin. Chem., Vol. 8, 2000, p. 1099-1105.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    The status of half-cystine residues and locations of N-glycosylated asparagine residues in human eosinophil peroxidase. / Thomsen, A.R.; Sottrup-Jensen, L.; Gleich, G.J.; Oxvig, C.

    In: Arch. Biochem. Biophys., Vol. 379, No. 1, 2000, p. 147-152.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. 1999
  33. Published

    Biochemical evidence for heme linkage through esters with Asp93 and Glu214 in human eosinophil peroxidase. The ester with Asp93 is only partially formed in vivo. / Oxvig, C.; Thomsen, A.R.; Overgaard, M.T.; Sørensen, E.S.; Højrup, P.; Bjerrum, M.J.; Gleich, G.J.; Sottrup-Jensen, L.

    In: Journal of Biological Chemistry, Vol. 274, 1999, p. 16953-16958.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A. / Conover, C.A.; Oxvig, C.; Overgaard, M.T.; Christiansen, M.; Giudice, L.C.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 84, 1999, p. 4742-4745.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and proform of eosinophil major basic protein: Expression in reproductive and nonreproductive tissues. / Overgaard, M.T.; Oxvig, C.; Christiansen, M.; Gleich, G.J.; Sottrup-Jensen, L.; Haaning, J.

    In: Biol. Reprod., Vol. 61, 1999, p. 1083-1089.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch. / Loechel, F.; Overgaard, M.T.; Oxvig, C.; Albrechtsen, R.; Wewer, U.M.

    In: Journal of Biological Chemistry, Vol. 274, 1999, p. 13427-13433.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    The insulin-like growth factor (IGF)-dependent IFG binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. / Lawrence, J.B.; Oxvig, C.; Overgaard, M.T.; Sottrup-Jensen, L.; Gleich, G.J.; Hays, L.G.; Yates III, J.R.; Conover, C.A.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, 1999, p. 3149-3153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    The proform of eosinophil major basic protein: A new maternal serum marker for Down syndrome. / Christiansen, M.; Oxvig, C.; Wagner, J.M.; Qin, Q.-P.; Nguyen, T.H.; Larsen, S.O.; Sottrup-Jensen, L.; Gleich, G.J.; Nørgaard-Pedersen, B.

    In: Prenatal Diagnosis, Vol. 19, 1999, p. 905-910.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. 1997
  40. Published

    Double-monoclonal immunofluorometric assays for pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/proMBP) complex in first-trimester maternal serum screening for Down syndrome. / Qin, Qui-Ping; Christiansen, Michael; Oxvig, Claus; Pettersson, Kim; Sottrup-Jensen, Lars; Koch, Claus; Nørgaard-Pedersen, Bent.

    In: Clinical Chemistry, Vol. 43, No. 12, 12.1997, p. 2323-2332.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    Simple and reliable procedure for PCR amplification of genomic DNA from yeast cells using short sequencing primers. / Haaning, J; Oxvig, C; Overgaard, Michael Toft; Sottrup-Jensen, L.

    In: IUBMB Life, Vol. 42, No. 1, 1997, p. 169-72.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 1996
  43. Published

    Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP. / Haaning, Jesper; Oxvig, Claus; Overgaard, Michael Toft; Ebbesen, Peter; Kristensen, Torsten; Sottrup-Jensen, Lars.

    In: European Journal of Biochemistry, Vol. 237, No. 1, 04.1996, p. 159-163.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. 1995
  45. Published

    Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma. / Oxvig, Claus; Haaning, Jesper; Kristensen, Lene; Wagner, Jill M; Rubin, Inger; Stigbrand, Torgny; Gleich, Gerald J; Sottrup-Jensen, Lars.

    In: Journal of Biological Chemistry, Vol. 270, No. 23, 09.06.1995, p. 13645-13651.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published
    Homo sapiens Pregnancy-associated plasma protein-A mRNA, complete cds. Genbank accession U28727. Haaning, J (Producer); Oxvig, Claus (Producer); Overgaard, M T (Producer); Ebbesen, P (Producer); Kristensen, Torsten (Producer); Sottrup-Jensen, Lars (Producer). 1995.

    Research output: Non-textual formDatasetResearch

  47. 1994
  48. Published

    Isolation and characterization of circulating complex between human pregnancy-associated plasma protein-A and proform of eosinophil major basic protein. / Oxvig, Claus; Sand, Ole; Kristensen, Torsten; Kristensen, Lene; Sottrup-Jensen, Lars.

    In: BBA General Subjects, Vol. 1201, No. 3, 15.12.1994, p. 415-423.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Biochemical properties, activities, and presence in biologic fluids of eosinophil granule major basic protein. / Popken-Harris, Pamela; Thomas, Larry; Oxvig, Claus; Sottrup-Jensen, Lars; Kubo, Hirokazu; Klein, J S; Gleich, Gerald J.

    In: Journal of Allergy and Clinical Immunology, Vol. 94, No. 6 Pt 2, 12.1994, p. 1282-1289.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta. / Bonno, M; Oxvig, Claus; Kephart, G M; Wagner, J M; Kristensen, Torsten; Sottrup-Jensen, L; Gleich, G J.

    In: Laboratory Investigation, Vol. 71, No. 4, 10.1994, p. 560-566.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. Published

    Location and nature of carbohydrate groups in proform of human major basic protein isolated from pregnancy serum. / Oxvig, Claus; Haaning, J; Højrup, Peter; Sottrup-Jensen, Lars.

    In: Biochemistry and Molecular Biology International, Vol. 33, No. 2, 05.1994, p. 329-336.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    Localization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic protein. / Oxvig, Claus; Gleich, G J; Sottrup-Jensen, Lars.

    In: FEBS Letters, Vol. 341, No. 2-3, 21.03.1994, p. 213-217.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA. / Kristensen, Torsten; Oxvig, Claus; Sand, Ole; Moeller, Niels Peter Hundahl; Sottrup-Jensen, Lars.

    In: Biochemistry, Vol. 33, No. 6, 15.02.1994, p. 1592-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. 1993
  55. Published

    Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein. / Oxvig, Claus; Sand, Ole; Kristensen, Torsten; Gleich, Gerald J; Sottrup-Jensen, Lars.

    In: Journal of Biological Chemistry, Vol. 268, No. 17, 15.06.1993, p. 12243-12246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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