Aarhus University Seal / Aarhus Universitets segl

Claus Oxvig

  1. 2022
  2. Published

    Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy. / Jepsen, Malene R; Østergaard, Jakob A; Conover, Cheryl A et al.

    In: Metabolism: Clinical and Experimental, Vol. 132, 155218, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Pregnancy-associated plasma protein-A (PAPP-A) is a key component of an interactive cellular mechanism promoting pulmonary fibrosis. / Bale, Laurie K.; Schafer, Marissa J.; Atkinson, Elizabeth J. et al.

    In: Journal of Cellular Physiology, Vol. 237, No. 4, 04.2022, p. 2220-2229.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Characterisation of the Stromal Microenvironment in Lobular Breast Cancer. / Gómez-Cuadrado, Laura; Bullock, Esme; Mabruk, Zeanap et al.

    In: Cancers, Vol. 14, No. 4, 904, 02.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. 2021
  6. Published

    Metabolic improvement after gastric bypass correlates with changes in IGF-regulatory proteins stanniocalcin-2 and IGFBP-4. / Hjortebjerg, Rikke; Bojsen-Møller, Kirstine N.; Søeby, Mette et al.

    In: Metabolism: Clinical and Experimental, Vol. 124, 154886, 11.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Zebrafish let you see how blood clearance of "non-self" nanoparticles triggers inflammation. / Mohammad-Beigi, Hossein; Takamiya, Masanari; Jensen, Pia Bomholt et al.

    2021. Poster session presented at The 16th International Zebrafish Conference.

    Research output: Contribution to conferencePosterResearch

  8. Published

    Superoxide dismutase 3 is expressed in bone tissue and required for normal bone homeostasis and mineralization. / Matthiesen, Cecilie L.; Hu, Lili; Torslev, Astrid S. et al.

    In: Free Radical Biology and Medicine, Vol. 164, 02.2021, p. 399-409.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2020
  10. Published

    Expression of the Insulin-like Growth Factor System in First- and Second-Trimester Human Embryonic and Fetal Gonads. / Mamsen, Linn Salto; Aikaterini, Zafeiri; Bøtkjær, Jane Alrø et al.

    In: The Journal of clinical endocrinology and metabolism, Vol. 105, No. 9, dgaa470, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Pregnancy-Associated Plasma Protein-A2 Is Associated With Mortality in Patients With Lung Cancer. / Hjortebjerg, Rikke; Espelund, Ulrick; Rasmussen, Torben Riis et al.

    In: Frontiers in Endocrinology, Vol. 11, 614, 09.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Tracing the In Vivo Fate of Nanoparticles with a "Non-Self" Biological Identity. / Mohammad-Beigi, Hossein; Scavenius, Carsten; Jensen, Pia Bomholt et al.

    In: ACS Nano, Vol. 14, No. 8, 08.2020, p. 10666-10679.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    The metalloproteinase papp-aa controls epithelial cell quiescence-proliferation transition. / Liu, Chengdong; Li, Shuang; Noer, Pernille Rimmer et al.

    In: eLife, Vol. 9, e52322, 04.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution. / Hayashi, Yuya; Takamiya, Masanari; Jensen, Pia Bomholt et al.

    In: ACS Nano, Vol. 14, No. 2, 01.2020, p. 1665-1681.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. / Lloyd, Katie A.; Parsons, Bryony N.; Burkitt, Michael D. et al.

    In: Cellular and Molecular Gastroenterology and Hepatology, Vol. 10, No. 1, 01.2020, p. 113-132.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood. / Fujimoto, Masanobu; Khoury, Jane C.; Khoury, Philip R. et al.

    In: European Journal of Endocrinology, Vol. 182, No. 3, 2020, p. 363-374.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Metalloproteinase PAPP - A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis. / Kashyap, Sonu; Hein, Kyaw Zaw; Chini, Claudia C.S. et al.

    In: JCI Insight, Vol. 5, No. 4, e135700, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2019
  19. Published

    PAPP-A and the IGF system in atherosclerosis : what's up, what's down? / Steffensen, Lasse B.; Conover, Cheryl A.; Oxvig, Claus.

    In: American journal of physiology. Heart and circulatory physiology, Vol. 317, No. 5, 11.2019, p. H1039-H1049.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma : Role in Tumor Growth and Immune Evasion. / Heitzeneder, Sabine; Sotillo, Elena; Shern, Jack F. et al.

    In: Journal of the National Cancer Institute, Vol. 111, No. 9, 209, 09.2019, p. 970-982.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Transcription profile of the insulin-like growth factor signaling pathway during human ovarian follicular development. / Botkjaer, Jane Alro; Pors, Susanne Elisabeth; Petersen, Tonny Studsgaard et al.

    In: Journal of Assisted Reproduction and Genetics, Vol. 36, No. 5, 05.2019, p. 889-903.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins. / Botkjaer, Jane Alro; Noer, Pernille Rimmer; Oxvig, Claus et al.

    In: Scientific Reports, Vol. 9, No. 1, 13231, 2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. 2018
  24. Published

    Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer. / Smith, Y. E.; Toomey, S.; Napoletano, S. et al.

    In: BMC Cancer, Vol. 18, 1016, 22.10.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs) : Potential co-ordinated regulation of IGF action. / Al-Khafaji, Hasanain; Noer, Pernille R.; Alkharobi, Hanna et al.

    In: Growth Hormone and IGF Research, Vol. 42-43, 10.2018, p. 14-21.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Corrigendum : Insulin-like growth factor-binding protein action in bone tissue: A key role for pregnancy-associated plasma protein - A (Frontiers in Endocrinology (2018) 9:31 DOI: 10.3389/fendo.2018.00031). / Beattie, James; Al-Khafaji, Hasanain; Noer, Pernille R. et al.

    In: Frontiers in Endocrinology, Vol. 9, No. SEP, 510, 04.09.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperComment/debate/letter to the editorResearchpeer-review

  27. Published

    40 years of IGF1 : PAPP-A and cancer. / Conover, Cheryl A.; Oxvig, Claus.

    In: Journal of Molecular Endocrinology, Vol. 61, No. 1, 01.07.2018, p. T1-T10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  28. Published

    Prognostic relevance and performance characteristics of serum IGFBP-2 and PAPP-A in women with breast cancer: a long-term Danish cohort study. / Espelund, Ulrick; Renehan, Andrew G; Cold, Søren et al.

    In: Cancer Medicine, Vol. 7, No. 6, 06.2018, p. 2391-2404.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction. / Cediel, Germán; Rueda, Ferran; Oxvig, Claus et al.

    In: Cardiovascular Diabetology, Vol. 17, 63, 30.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Depot-specific and GH-dependent regulation of IGF binding protein-4, pregnancy-associated plasma protein-A, and stanniocalcin-2 in murine adipose tissue. / Hjortebjerg, Rikke; Berryman, Darlene E; Comisford, Ross et al.

    In: Growth Hormone & I G F Research, Vol. 39, 04.2018, p. 54-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Insulin- like growth factor-binding protein action in bone tissue : A key role for pregnancy- associated plasma protein-A. / Beattie, James; Al-Khafaji, Hasanain; Noer, Pernille R. et al.

    In: Frontiers in Endocrinology, Vol. 9, 31, 16.02.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  32. 2017
  33. Published

    Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome. / Thorsen, Kasper; Dam, Vibeke S.; Kjaer-Sorensen, Kasper et al.

    In: Nature Communications, Vol. 8, No. 1, 1696, 01.12.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Effects of prednisolone on serum and tissue fluid IGF-I receptor activation and post-receptor signaling in humans. / Ramshanker, Nilani; Aagaard, Maiken; Hjortebjerg, Rikke et al.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 102, No. 11, 11.2017, p. 4031-4040.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Differential impact of glucose administered intravenously and orally on circulating miR-375 levels in human subjects. / Yan, Xin; Wang, Zhen; Westberg-Rasmussen, Sidse et al.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 102, No. 10, 01.10.2017, p. 3749-3755.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology. / Argente, Jesús; Chowen, Julie A; Pérez-Jurado, Luis A et al.

    In: EMBO Molecular Medicine, Vol. 9, No. 10, 01.10.2017, p. 1338-1345.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  37. Published

    Insulin-Like Growth Factor Bioactivity, Stanniocalcin-2, Pregnancy-Associated Plasma Protein-A, and IGF-Binding Protein-4 in Pleural Fluid and Serum From Patients With Pulmonary Disease. / Espelund, Ulrick Skipper; Bjerre, Mette; Hjortebjerg, Rikke et al.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 102, No. 9, 01.09.2017, p. 3526-3534.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    Identification of novel regulators of local MBP mRNA translation. / Steengaard, J.; Torvund-Jensen, J.; Askbjerg, L. et al.

    In: Glia, Vol. 65, No. Special issue, S1, T12-076C , 06.2017, p. E397-E397.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  39. Published

    The IGF system in patients with type 2 diabetes: associations with markers of cardiovascular target organ damage. / Hjortebjerg, Rikke; Laugesen, Esben; Høyem, Pernille et al.

    In: European Journal of Endocrinology. Supplement, Vol. 176, No. 5, 01.05.2017, p. 521-531.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    Endogenous Natural Complement Inhibitor Regulates Cardiac Development. / Mortensen, Simon A; Skov, Louise L; Kjaer-Sorensen, Kasper et al.

    In: Journal of Immunology, Vol. 198, No. 8, 15.04.2017, p. 3118-3126.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. Published

    PAPP-A : A promising therapeutic target for healthy longevity. / Conover, Cheryl A.; Oxvig, Claus.

    In: Aging Cell, Vol. 16, No. 2, 04.2017, p. 205-209.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Insulin-Like Growth Factor Binding Protein 4 Fragments Provide Incremental Prognostic Information on Cardiovascular Events in Patients With ST-Segment Elevation Myocardial Infarction. / Hjortebjerg, Rikke; Lindberg, Søren; Pedersen, Sune et al.

    In: Journal of the American Heart Association, Vol. 6, No. 3, e005358, 17.03.2017, p. 1-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Female versus male biological identities of nanoparticles determine the interaction with immune cells in fish. / Hayashi, Yuya; Miclaus, Teodora; Murugadoss, Sivakumar et al.

    In: Environmental Science: Nano, Vol. 4, No. 4, 03.03.2017, p. 895-906.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Rare and low-frequency coding variants alter human adult height. / Marouli, Eirini; Graff, Mariaelisa; Medina-Gómez, Carolina et al.

    In: Nature, Vol. 542, No. 7640, 09.02.2017, p. 186-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Pregnancy-Associated Plasma Protein-A2 and Anthropometry, Lifestyle, and Biochemical Factors in a Human Adult Population. / Steinbrecher, Astrid; Janke, Jürgen; Poy, Matthew N. et al.

    In: Scientific Reports, Vol. 7, No. 1, 10455, 2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    SERUM STANNIOCALCIN (STC) 2 LEVELS ARE INCREASED IN PREPUBERTAL OBESE CHILDREN. / Noer, Pernille R.; Guerra-Cantero, Santiago; Barrios, Vicente et al.

    In: Hormone Research in Paediatrics, Vol. 88, No. Supplement 1, 2017, p. 285-286.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  47. 2016
  48. Published

    Effect of pregnancy-associated plasma protein-A (PAPP-A) single-nucleotide polymorphisms on the level and activity of PAPP-A and the hormone profile in fluid from normal human small antral follicles. / Bøtkjær, Jane Alrø; Borgbo, Tanni; Kløverpris, Søren et al.

    In: Fertility and Sterility, Vol. 106, No. 7, 25.10.2016, p. 1778-1786.e8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    PAPP-A and the IGF system / La PAPP-A et le système des IGFs. / Monget, Philippe; Oxvig, Claus.

    In: Annales d'Endocrinologie, Vol. 77, No. 2, 06.2016, p. 90-96.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Reply : Methodological considerations in measuring different AMH splice forms using ELISA: validity of proAMH ELISA. / Mamsen, L S; Munthe-Fog, L; Petersen, T S et al.

    In: Molecular Human Reproduction, Vol. 22, No. 5, 05.2016, p. 374-375.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. Published

    Stanniocalcin-2 overexpression reduces atherosclerosis in hypercholesterolemic mice. / Steffensen, Lasse B; Conover, Cheryl A; Bjørklund, Martin M et al.

    In: Atherosclerosis, Vol. 248, 05.2016, p. 36-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development. / Jepsen, Malene R.; Kløverpris, Søren; Bøtkjær, Jane A. et al.

    In: Human Reproduction, Vol. 31, No. 4, 01.04.2016, p. 866-874.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Targeted Inhibition of Pregnancy-Associated Plasma Protein-A Activity Reduces Atherosclerotic Plaque Burden in Mice. / Conover, Cheryl A.; Bale, Laurie K.; Oxvig, Claus.

    In: Journal of Cardiovascular Translational Research, Vol. 9, No. 1, 01.02.2016, p. 77-79.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Transglutaminase 2-Catalyzed Intramolecular Cross-Linking of Osteopontin. / Christensen, Brian; Zachariae, Elias D; Scavenius, Carsten et al.

    In: Biochemistry, Vol. 55, No. 2, 19.01.2016, p. 294-303.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer. / Takabatake, Yukie; Oxvig, Claus; Nagi, Chandandeep et al.

    In: EMBO Molecular Medicine, Vol. 8, No. 4, 2016, p. 388-406.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability. / Dauber, Andrew; Muñoz-Calvo, María T; Barrios, Vicente et al.

    In: E M B O Reports, Vol. 8, No. 4, 2016, p. 363-74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    PAPP-A, IGFBP-4 and IGF-II are secreted by human adipose tissue cultures in a depot-specific manner. / Gude, Mette Faurholdt; Hjortebjerg, Rikke; Oxvig, Claus et al.

    In: European Journal of Endocrinology, Vol. 175, No. 6, 2016, p. 509-519.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Treatment with recombinant human insulin-like growth factor-I improves growth in patients with PAPP-A2 deficiency. / Teresa Muñoz-Calvo, María; Barrios, Vicente; Pozo, Jesús et al.

    In: The Journal of Clinical Endocrinology & Metabolism, Vol. 101, No. 11, 2016, p. 3879-3883.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. 2015
  60. Published

    Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A. / Kløverpris, Søren; Mikkelsen, Jakob Hauge; Pedersen, Josefine Hvidkjær et al.

    In: Journal of Biological Chemistry, Vol. 290, No. 36, 04.09.2015, p. 21915-21924.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    PAPP-A proteolytic activity enhances IGF bioactivity in ascites from women with ovarian carcinoma. / Thomsen, Jacob; Hjortebjerg, Rikke; Espelund, Ulrick et al.

    In: OncoTarget, Vol. 6, No. 31, 24.08.2015, p. 32266-32278.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    Pregnancy-associated plasma protein A in human ovarian follicles and its association with intrafollicular hormone levels. / Bøtkjær, Jane Alrø; Jeppesen, Janni Vikkelsø; Wissing, Marie Louise et al.

    In: Fertility and Sterility, Vol. 104, No. 5, 18.08.2015, p. 1294-1301.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Disturbed Laminar Blood Flow Vastly Augments Lipoprotein Retention in the Artery Wall : A Key Mechanism Distinguishing Susceptible From Resistant Sites. / Steffensen, Lasse Bach; Mortensen, Martin Bødtker; Kjolby, Mads et al.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 35, 16.07.2015, p. 1928-1935.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. Published

    Proteolytic processing of anti-Müllerian hormone differs between human fetal testes and adult ovaries. / Mamsen, Linn; Petersen, TS; Jeppesen, JV et al.

    In: Molecular Human Reproduction, Vol. 21, No. 7, 07.2015, p. 571-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    The role of PAPP-A in the IGF system : location, location, location. / Oxvig, Claus.

    In: Journal of Cell Communication and Signaling, Vol. 9, No. 2, 06.2015, p. 177-87.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    First trimester PAPP-A2, PAPP-A and hCGβ in small-for-gestational-age pregnancies. / Hansen, Young Bae; Myrhøj, Vibeke; Jørgensen, Finn Stener et al.

    In: Clinical Chemistry and Laboratory Medicine, Vol. 54, No. 1, 12.05.2015, p. 117-123.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgrafts. / Becker, Marc A; Haluska, Paul; Bale, Laurie K et al.

    In: Molecular Cancer Therapeutics, Vol. 14, No. 4, 04.2015, p. 973-981.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  68. Published

    PAPP-A and IGFBP-4 fragment levels in patients with ST-elevation myocardial infarction treated with heparin and PCI. / Hjortebjerg, Rikke; Lindberg, Søren; Jensen, Jan S et al.

    In: Clinical Biochemistry, Vol. 148, No. 4-5, 03.2015, p. 322-328.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Stanniocalcin-2 Inhibits Mammalian Growth by Proteolytic Inhibition of the Insulin-like Growth Factor Axis. / Jepsen, Malene R; Kloverpris, Soren; Mikkelsen, Jakob Hauge et al.

    In: Journal of Biological Chemistry, Vol. 290, 06.02.2015, p. 3430-3439.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  70. Published

    Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes. / Søndergaard, Mads T; Sorensen, Anders B; Skov, Louise L et al.

    In: F E B S Journal, Vol. 282, No. 4, 02.2015, p. 803-816.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  71. Published

    Myocardial and Peripheral Ischemia Causes an Increase in Circulating Pregnancy-Associated Plasma Protein-A in Non-atherosclerotic, Non-heparinized Pigs. / Steffensen, Lasse Bach; Poulsen, Christian Bo; Shim, Jeong et al.

    In: Journal of Cardiovascular Translational Research, Vol. 8, No. 9, 2015, p. 528-535.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  72. 2014
  73. Published

    Identification of transglutaminase reactive residues in human osteopontin and their role in polymerization. / Christensen, Brian ; Zachariae, Elias D; Scavenius, Carsten et al.

    In: PLOS ONE, Vol. 9, No. 11, e113650, 11.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published

    Pregnancy-associated plasma protein-A expression in human breast cancer. / Mansfield, Aaron S; Visscher, Daniel W; Hart, Steven N et al.

    In: Growth Hormone & I G F Research, Vol. 24, No. 6, 31.10.2014, p. 264-267.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Pregnancy-associated plasma protein-A2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos. / Kjaer-Sorensen, Kasper; Engholm, Ditte Høyer; Jepsen, Malene R et al.

    In: Journal of Cell Science, 18.09.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    Development of a recombinant antibody towards PAPP-A for immunohistochemical use in multiple animal species. / Mikkelsen, Jakob H; Steffensen, Lasse B; Oxvig, Claus.

    In: Journal of Immunological Methods, Vol. 404, 02.2014, p. 33-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity. / Mikkelsen, Jakob H; Resch, Zachary T; Kalra, Bhanu et al.

    In: OncoTarget, Vol. 5, No. 4, 20.01.2014, p. 1014-1025.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. 2013
  79. Published

    Zebrafish as a novel model to assess Na+/K+-ATPase-related neurological disorders. / Doğanli, Canan; Oxvig, Claus; Lykke-Hartmann, Karin.

    In: Neuroscience & Biobehavioral Reviews, Vol. 37, No. 10 Part2, 12.2013, p. 2774–2787.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  80. Published

    Molecular Cloning and Characterization of Porcine Na+/K+-ATPase Isoforms α1, α2, α3 and the ATP1A3 Promoter. / Henriksen, Carina; Kjaer-Sorensen, Kasper; Einholm, Anja Pernille et al.

    In: P L o S One, Vol. 8, No. 11, e79127, 13.11.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    A robust immunoassay for pregnancy-associated plasma protein-A2 based on analysis of circulating antigen : establishment of normal ranges in pregnancy. / Kløverpris, Søren; Gaidamauskas, Ervinas; Rasmussen, Louise Carøe Vohlander et al.

    In: Molecular Human Reproduction, Vol. 19, No. 11, 11.2013, p. 756-763.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  82. Published

    Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy. / Mader, Jessica R; Resch, Zachary T; McLean, Gary R et al.

    In: Journal of Endocrinology, Vol. 219, No. 1, 01.10.2013, p. 51-58.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Pregnancy-associated plasma protein-A (PAPP-A) modulates early developmental rate in zebrafish independent of its proteolytic activity. / Kjær-Sørensen, Kasper; Engholm, Ditte Høyer; Kamei, Hiroyasu et al.

    In: Journal of Biological Chemistry, Vol. 288, 04.2013, p. 9982-9992.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    α3Na+/K+-ATPase deficiency causes brain ventricle dilation and abrupt embryonic motility in zebrafish. / Doganli, Canan; Beck, Hans Christian; Ribera, Angeles B et al.

    In: Journal of Biological Chemistry, Vol. 288, 29.03.2013, p. 8862-8874.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. Published

    IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A) : multiple PAPP-A-IGFBP interaction sites. / Gaidamauskas, Ervinas; Nielsen, Claus Gyrup; Boldt, Henning Bünsow et al.

    In: BBA General Subjects, Vol. 1830, No. 3, 03.2013, p. 2701-2709.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. Published

    Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein. / Kløverpris, Søren; Skov, Louise Lind; Glerup, Simon et al.

    In: Biochemical Journal, Vol. 449, No. 1, 01.01.2013, p. 209-217.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice. / Boldt, Henning B; Bale, Laurie K; Resch, Zachary T et al.

    In: Endocrinology, Vol. 154, No. 1, 01.2013, p. 246-252.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Porcine synapsin 1: SYN1 gene analysis and functional characterization of the promoter. / Hedegaard, Claus; Kjaer-Sorensen, Kasper; Madsen, Lone Bruhn et al.

    In: F E B S Open Bio, Vol. 3, 2013, p. 411–420.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  89. 2012
  90. Published

    The α2Na+/K+-ATPase is critical for skeletal and heart muscle function in zebrafish. / Doganli, Canan; Kjaer-Sørensen, Kasper; Knoeckel, Christopher et al.

    In: Journal of Cell Science, Vol. 125, 12.2012, p. 6166-6175.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  91. 2011
  92. Published

    ATP1alpah3-Zebrafish as a model of Dystonia. / Doganli, Canan; Nyengaard, Jens Randel; Nissen, Poul et al.

    2011.

    Research output: Contribution to conferencePosterResearch

  93. 2010
  94. Published

    Early developmental expression of mus musculus zinc finger RNA-binding protein compared to orthologs in caenorhabditis elegans and danio rerio and subcellular localization of mus musculus and caenorhabditis elegans zinc finger rna-binding protein in 2-cell mus musculus embryos. / Doǧanli, Canan; Kjærgaard, Tine; Olsen, Anders et al.

    In: DNA and Cell Biology, Vol. 29, No. 12, 01.12.2010, p. 713-727.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  95. Published

    Early Developmental Expression of Mus musculus ZFR compared to orthologs in Caenorhabditis elegans and Danio rerio and subcellular localization of M. musculus and C. elegans ZFR in 2-cell M. musculus embryos. / Doganli, Canan; Kjærgaard, Tine; Olsen, Anders et al.

    In: D N A and Cell Biology, Vol. 29, No. 12, 12.2010, p. 713-27.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  96. Published

    Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development. / Conover, Cheryl A; Mason, Megan A; Bale, Laurie K et al.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 299, No. 2, 01.08.2010, p. 284-291.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  97. Published

    Biology of pregnancy-associated plasma protein-A in relation to prenatal diagnostics: an overview. / Kirkegaard, Ida; Uldbjerg, Niels; Oxvig, Claus.

    In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 89, No. 9, 2010, p. 1118-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. 2008
  99. Published

    Duplication and Diversification of the Hypoxia-Inducible IGFBP-1 Gene in Zebrafish. / Kamei, Hiroyasu; Lu, Ling; Jiao, Shuang et al.

    In: P L o S One, Vol. 3, No. 8, 12.2008, p. e3091.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding. / Mikkelsen, Jakob Hauge; Nielsen, Claus Gyrup; Kristensen, Peter et al.

    In: Journal of Biological Chemistry, Vol. 283, No. 24, s. 16772-80, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein. / Parkyn, Celia J; Vermeulen, Esmeralda G M; Mootoosamy, Roy C et al.

    In: Journal of Cell Science, 2008.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. Published

    Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2. / Winn, Virginia D; Gormley, Matthew; Paquet, Agnes C et al.

    In: Endocrinology, Vol. 150, No. 1, 2008, p. 452-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  103. Published

    Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin administration. / Terkelsen, Christian J; Oxvig, Claus; Nørgaard, Bjarne L et al.

    In: American Journal of Cardiology, Vol. 103, No. 1, 2008, p. 29-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. 2007
  105. Published

    Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor. / Glerup, Simon; Kløverpris, Søren; Laursen, Lisbeth S et al.

    In: Journal of Biological Chemistry, Vol. 282, No. 3, 19.01.2007, p. 1769-1778.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. Published

    A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module. / Weyer, Kathrin; Boldt, Henning B; Poulsen, Christine B et al.

    In: Journal of Biological Chemistry, Vol. 282, No. 15, 2007, p. 10988-99.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. Published

    Quantification of proteolytically active pregnancy-associated plasma protein-A using an assay based on quenched fluorescence. / Nielsen, Claus Gyrup; Christiansen, M.; Oxvig, Claus.

    In: Clin. Chem., Vol. 53, 2007, p. 947-954.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. Published

    Quantitative analysis of insulin-like growth factor (IGF) modulated proteolysis of IGF binding protein-4 and -5 by pregnancy-associated plasma protein-A. / Nielsen, Claus Gyrup; Oxvig, Claus.

    In: Biochemistry, Vol. 46, 2007, p. 1982-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. Published

    The structural basis of calcium transport by the calcium pump. / Olesen, Claus; Picard, Martin; Winther, Anne-Marie Lund et al.

    In: Nature, Vol. 450, No. 7172, 2007, p. 1036-1042.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  110. 2006
  111. Published

    The proform of the eosinophil major basic protein binds the cell surface through a site distinct from its C-type lectin ligand-binding region. / Glerup, Simon; Kløverpris, Søren; Oxvig, Claus.

    In: Journal of Biological Chemistry, Vol. 281, No. 42, 20.10.2006, p. 31509-31516.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  112. Published

    Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol. / Conover, Cheryl A.; Bale, Laurie K.; Harrington, Sean C. et al.

    In: Am. J. Physiol. (Cell Physiol.), Vol. 290, No. 1, 2006, p. C183-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  113. Published

    Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules. / Boldt, Henning Bünsow; Glerup, Simon; Overgaard, Michael Toft et al.

    In: Protein Expr Purif., Vol. 48, No. 2, 2006, p. 261-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  114. Published

    Haptoglobin-related protein is a high-affinity hemoglobin-binding plasma protein. / Nielsen, Marianne Jensby; Petersen, Steen Vang; Jacobsen, Christian et al.

    In: Blood, Vol. 108, No. 8, 2006, p. 2846-2849.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  115. Published
  116. Published

    Pregnancy-associated plasma protein-A is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events. / Sangiorigi, G.; Mauriello, A.; Bonanno, E. et al.

    In: Journal of the American College of Cardiology, Vol. 47, 2006, p. 2201-2211.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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