Claus Olesen

  1. 2019
  2. Published

    Structures of the heart specific SERCA2a Ca 2+ -ATPase. / Sitsel, Aljona; De Raeymaecker, Joren; Drachmann, Nikolaj Düring; Derua, Rita; Smaardijk, Susanne; Andersen, Jacob Lauwring; Vandecaetsbeek, Ilse; Chen, Jialin; De Maeyer, Marc; Waelkens, Etienne; Olesen, Claus; Vangheluwe, Peter; Nissen, Poul.

    In: EMBO Journal, Vol. 38, No. 5, e100020, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2018
  4. Published

    Membrane-protein crystals for neutron diffraction. / Sørensen, Thomas Lykke Møller; Hjorth-Jensen, Samuel John; Oksanen, Esko; Andersen, Jacob Lauwring; Olesen, Claus; Møller, Jesper Vuust; Nissen, Poul.

    In: Acta crystallographica Section D: Structural biology , Vol. 74, No. Pt 12, 01.12.2018, p. 1208-1218.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering. / Midtgaard, Søren Roi; Darwish, Tamim A.; Pedersen, Martin Cramer; Huda, Pie; Larsen, Andreas Haahr; Jensen, Grethe Vestergaard; Kynde, Søren Andreas Røssell; Skar-Gislinge, Nicholas; Nielsen, Agnieszka Janina Zygadlo; Olesen, Claus; Blaise, Mickael; Dorosz, Jerzy Józef; Thorsen, Thor Seneca; Venskutonyte, Raminta; Krintel, Christian; Møller, Jesper V.; Frielinghaus, Henrich; Gilbert, Elliot Paul; Martel, Anne; Kastrup, Jette Sandholm; Jensen, Poul Erik; Nissen, Poul; Arleth, Lise.

    In: FEBS Journal, Vol. 285, No. 2, 01.2018, p. 357-371.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2017
  7. Published

    Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response. / Sehgal, Pankaj; Szalai, Paula; Olesen, Claus; Praetorius, Helle A; Nissen, Poul; Christensen, Søren Brøgger; Engedal, Nikolai; Møller, Jesper Vuust.

    In: Journal of Biological Chemistry, Vol. 292, 12.2017, p. 19656-19673.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2016
  9. Published

    Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand Jean-Paul; Olesen, Claus; Andersen, Jens Peter; Møller, Jesper Vuust; Nissen, Poul.

    In: Structure, Vol. 24, No. 4, 05.04.2016, p. 617-623.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Lipid exchange by ultracentrifugation. / Drachmann, Nikolaj Düring; Olesen, Claus.

    P-Type ATPases. Methods and Protocols. New York : Springer, 2016. p. 397-402 (Methods in Molecular Biology, Vol. 1377).

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  11. 2015
  12. Published

    Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. / Bublitz, Maike; Nass, Karol; Drachmann, Nikolaj D; Markvardsen, Anders J; Gutmann, Matthias J; Barends, Thomas R M; Mattle, Daniel; Shoeman, Robert L; Doak, R Bruce; Boutet, Sébastien; Messerschmidt, Marc; Seibert, Marvin M; Williams, Garth J; Foucar, Lutz; Reinhard, Linda; Sitsel, Oleg; Gregersen, Jonas L; Clausen, Johannes D; Boesen, Thomas; Gotfryd, Kamil; Wang, Kai-Tuo; Olesen, Claus; Møller, Jesper V; Nissen, Poul; Schlichting, Ilme.

    In: IUCrJ, Vol. 2, No. Pt 4, 01.07.2015, p. 409-420.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Na,K-ATPase structure/function relationships probed by the denaturant urea. / Esmann, Mikael; Fedosova, Natalya U; Olesen, Claus.

    In: B B A - Biomembranes, Vol. 1848, No. 5, 05.2015, p. 1212-1223.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca(2+)-ATPase Inhibitors and Structure-Activity Relationships. / de Ford , Christian ; Calderon, Carlos; Sehgal, Pankaj; Fedosova, Natalya; Murillo, Renato ; Olesen, Claus; Nissen, Poul; Møller, Jesper Vuust; Merfort, Irmgard.

    In: Journal of Natural Products, Vol. 78 (6), 2015, p. 1262–1270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. 2014
  16. Published

    S-Palmitoylation and S-Oleoylation of Rabbit and Pig Sarcolipin. / Montigny, Cédric; Decottignies, Paulette; le Maréchal, Pierre; Capy, Pierre; Bublitz, Maike; Olesen, Claus; Møller, Jesper Vuust; le Maire, Marc; Nissen, Poul.

    In: Journal of Biological Chemistry, Vol. 289, 05.12.2014, p. 33850-33861.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Comparing crystal structures of Ca2+-ATPase in the presence of different lipids. / Drachmann, Nikolaj D; Olesen, Claus; Møller, Jesper V; Guo, Zheng; Bublitz, Maike; Nissen, Poul.

    In: F E B S Journal, Vol. 281, No. 18, 09.2014, p. 4249-4262.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2013
  19. Published

    Ion Pathways in the Sarcoplasmic Reticulum Ca2+-ATPase. / Bublitz, Maike; Musgaard, Maria; Poulsen, Hanne; Thøgersen, Lea; Olesen, Claus; Schiøtt, Birgit; Morth, Preben; Møller, Jesper V; Nissen, Poul.

    In: Journal of Biological Chemistry, Vol. 288, 12.04.2013, p. 10759-10765.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase. / Paulsen, Eleonora S; Villadsen, Jesper; Tenori, Eleonora; Liu, Huizhen; Bonde, Ditte Fast; Lie, Mette Alstrup; Bublitz, Maike; Olesen, Claus; Autzen, Henriette Elisabeth; Dach, Ingrid; Sehgal, Pankaj; Nissen, Poul; Møller, Jesper Vuust; Schiøtt, Birgit; Christensen, SB.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 9, 04.2013, p. 3609-3619.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. 2012
  22. Published

    Active Detergent-solubilized H+,K+-ATPase Is a Monomer. / Dach, Ingrid; Olesen, Claus; Signor, Luca; Nissen, Poul; le Maire, Marc; Møller, Jesper V; Ebel, Christine.

    In: Journal of Biological Chemistry, Vol. 287, 07.12.2012, p. 41963-41978.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy. / Denmeade, Samuel R; Mhaka, Annastasiah M; Rosen, D Marc; Brennen, W Nathaniel; Dalrymple, Susan; Dach, Ingrid; Olesen, Claus; Gurel, Bora; Demarzo, Angelo M; Wilding, George; Carducci, Michael A; Dionne, Craig A; Møller, Jesper V; Nissen, Poul; Christensen, Søren Brøgger; Isaacs, John T.

    In: Science Translational Medicine, Vol. 4, No. 140, 27.06.2012, p. 140ra86.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2011
  25. Published

    HiLiDe—Systematic Approach to Membrane Protein Crystallization in Lipid and Detergent. / Gourdon, Pontus; Andersen, Jacob Lauwring; Hein, Kim Langmach; Bublitz, Maike; Pedersen, Bjørn Panyella; Liu, Xiang-Yu; Yatime, Laure; Nyblom, Maria; Nielsen, Thorbjørn Terndrup; Olesen, Claus; Møller, Jesper Vuust; Nissen, Poul; Morth, Jens Preben.

    In: Crystal Growth & Design, Vol. 11, No. 6, 2011, p. 2098-2106.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes. / Sonntag, Yonathan; Musgaard, Maria; Olesen, Claus; Schiøtt, Birgit; Møller, Jesper Vuust; Nissen, Poul; Thøgersen, Lea.

    In: Nature Communications, Vol. 2, 2011, p. 304.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Rb+ occlusion stabilized by vanadate in gastric H+/K+-ATPase at 25 oC. / Montes, Monica R.; Spiaggi, Alejandro J.; Monti, Jose L. E.; Cornelius, Flemming; Olesen, Claus; Garrahan, Patricio J.; Rossi, Rolando C.

    In: B B A - Biomembranes, Vol. 1808, 2011, p. 316-322.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2010
  29. Published

    Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs. / Winther, Anne-Marie Lund; Liu, Huizhen; Sonntag, Yonathan; Olesen, Claus Elsborg; le Maire, Marc; Søhoel, Helmer; Olsen, Carl Erik; Christensen, Søren Brøgger; Nissen, Poul; Møller, Jesper Vuust.

    In: Journal of Biological Chemistry, Vol. 285, No. 37, 2010, p. 28883-92.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. / Skytte, DM; Møller, Jesper Vuust; Liu, H; Nielsen, HØ; Svenningsen, LE; Jensen, CM; Olesen, Claus; Christensen, SB.

    In: Bioorganic & Medicinal Chemistry, Vol. 18, 2010, p. 5634-5646.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump. / Møller, Jesper Vuust; Olesen, Claus Elsborg; Winther, Anne-Marie Lund; Nissen, Poul.

    In: Quarterly Reviews of Biophysics, Vol. 43, No. 4, 2010, p. 501-566.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    What can be learned about the function of a single protein from its various X-ray structures: the example of the sarcoplasmic calcium pump. / Møller, Jesper Vuust; Olesen, Claus Elsborg; Winther, Anne-Marie Lund; Nissen, Poul.

    Methods in Molecular Biology: Membrane Protein Structure Determination Methods and Protocols. Vol. 654, Part 2 Humana Press, 2010. p. 119-140.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  33. 2009
  34. Published

    Cyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPase. / Laursen, Mette; Bublitz, Maike; Moncoq, Karine; Olesen, Claus; Møller, Jesper Vuust; Young, Howard; Nissen, Poul; Morth, Jens Preben.

    In: Journal of Biological Chemistry, Vol. 284, No. 20, 15.06.2009, p. 13513-13518.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    A first low-resolution difference Fourier map of phosphorus in a membrane protein from near-edge anomalous diffraction. / Boesecke, Peter; Bois, Jean Marie; Crëpin, Thibaut; Hunte, Carola; Kahn, Richard; Kao, Wei-Chun; Nauton, Lionel; Winther, Anne-Marie Lund; Møller, Jesper Vuust; Nissen, Poul; Nury, Hughes; Olesen, Claus Elsborg; Pebay-Peyroula, Eva; Vicat, Jean; Stuhrmann, Heinrich.

    In: Journal of Synchrotron Radiation, Vol. 16, No. 5, 2009, p. 658-665.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    P-type ATPases as drug targets: Tools for medicine and science. / Yatime, Laure; Buch-Pedersen, Morten Jeppe; Musgaard, Maria; Morth, Jens Preben; Winther, Anne-Marie Lund; Pedersen, Bjørn Panyella; Olesen, Claus Elsborg; Andersen, Jens Peter; Vilsen, Bente; Schiøtt, Hanne Birgit; Palmgren, Michael; Møller, Jesper Vuust; Nissen, Poul; Fedosova, Natalya.

    In: B B A - Bioenergetics, Vol. 1787, No. 4, 2009, p. 207-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. 2008
  38. Published

    Crystal Structure of D351A and P312A Mutant Forms of the Mammalian Sarcoplasmic Reticulum Ca2+-ATPase Reveals Key Events in Phosphorylation and Ca2+ Release. / Marchand, Alexandre; Winther, Anne-Marie Lund; Holm, Peter; Olesen, Claus; Montigny, Cedric; Arnou, Bertrand; Champeil, Philippe; Clausen, Johannes D.; Vilsen, Bente; Andersen, Jens Peter; Nissen, Poul; Jaxel, Christine; Møller, Jesper Vuust; le Maire, Marc.

    In: Journal of Biological Chemistry, Vol. 283, No. 21, 2008, p. 14867-14882.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Gel chromatography and analytical ultracentrifugation to determine the extent of detergent binding and aggregation, and Stokes radius of membrane proteins using sarcoplasmic reticulum Ca2+-ATPase as an example. / le Marie, M; Arnou, Bertrand Jean-Paul; Olesen, Claus; Georgin, D; Ebel, C; Møller, Jesper Vuust.

    In: Nature Protocols (Print), Vol. 3, 2008, p. 1782-1795.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. 2007
  41. Published

    The structural basis of calcium transport by the calcium pump. / Olesen, Claus; Picard, Martin; Winther, Anne-Marie Lund; Nielsen, Claus Gyrup; Morth, Jens Preben; Oxvig, Claus; Møller, Jesper Vuust; Nissen, Poul.

    In: Nature, Vol. 450, No. 7172, 2007, p. 1036-1042.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. 2006
  43. Published

    Crystals of sarcoplasmic reticulum Ca2+-ATPase. / Sørensen, Thomas Lykke-Møller; Olesen, Claus; Jensen, Anne-Marie Lund; Møller, Jesper Vuust; Nissen, Poul.

    In: Journal of Biotechnology, Vol. 124, No. 4, 2006, p. 704-716.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Modulatory and catalytic modes of ATP binding by the calcium pump. / Jensen, Anne-Marie Lund; Sørensen, Thomas Lykke-Møller; Olesen, Claus; Møller, Jesper Vuust; Nissen, Poul.

    In: E M B O Journal, Vol. 25, No. 11, 2006, p. 2305-2314.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. 2005
  46. Published

    Relax! Molecular understanding of how the cacium pump works. / Sørensen, T.L.; Olesen, Claus; Nielsen, Rikke Christina; Møller, Jesper Vuust; Nissen, Poul.

    In: BESSY Highlights 2004, 2005.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  47. Published

    The structural basis for coupling of Ca2+ transport to ATP hydrolysis by the sarcoplasmic reticulum Ca2+-ATPase. / Møller, Jesper Vuust; Olesen, Claus; Jensen, Anne-Marie Lund; Nissen, Poul.

    In: J. Bioenerg. Biomembr., Vol. 37, No. 6, 2005, p. 359-364.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. 2004
  49. Published

    Dephosphorylation of the Calcium Pump Coupled to Counterion Occlusion. / Olesen, Claus; Sørensen, Thomas Lykke-Møller; Nielsen, R.C.; Møller, Jesper Vuust; Nissen, P.

    In: Science, Vol. 306, 2004, p. 2251-2255.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. 1986
  51. Published

    Screening for hypertension af 40-64-årige maend. / Jastrup, B; Faldborg, Lars; Hansen, Torben Bæk; Høyer, Morten; Lass, Preben; Olesen, Claus.

    In: Ugeskrift for Laeger, Vol. 148, No. 3, 13.01.1986, p. 119-121.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review