Projects per year
Personal profile
Profile
I lead a translational research program focused on gastrointestinal cancer, investigating the biological mechanisms underlying disease progression and treatment response. My research group is dedicated to the development of biomarkers and the clinical implementation of liquid biopsy technologies, particularly circulating tumor DNA (ctDNA). We conduct prospective biobank studies and interventional trials aimed at identifying and validating biomarkers that can guide personalized treatment decisions.
Job responsibilities
Mit primære ansvarsområde er forskning, herunder uddannelse af Bachelor, Master, og PHD studerende. Jeg varetager daglig forskningsledelse, vejledning af yngre forskere og udvikling af forskningsprojekter i samarbejde med nationale og internationale partnere. Jeg er PI på nationale kliniske forsøg og deltager i store europæiske forskningsprojekter financieret af EU, feks. GUIDE.MRD (https://www.guidemrd-horizon.eu/).
Jeg er leder af det Nationale Kræftforsknings center "THE DANISH NATIONAL CENTER FOR CIRCULATING TUMOR DNA GUIDED CANCER TREATMENT"(ctDNA.dk).
Keywords
- Bioinformatics
- microarray data
- Cancer
- Cancer
- Digestive tract
Areas of expertise
- Colorectal Cancer
- Gastrointestinal cancer
- Translational Cancer Research
- Cirkulating tumor DNA
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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RESPONSE: RESPONSE: Colorectal cancer survivors’ follow-up care – now digital and need-based. A national interventional effectiveness trial for stage I and II patients.
Ørntoft, M.-B. W. (Project coordinator), Iversen, L. H. (PI), Andersen, C. L. (PI), Zachariae, R. (Collaborator), Sopina, L. (Collaborator), Thorlacius-Ussing, O. (PI) & Christensen, P. (PI)
01/05/2024 → 01/05/2030
Project: Research
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ISCOLIM: Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation
Kirkegård, J. (Participant), Mortensen, F. V. (PI), Lund, A. (Participant), Andersen, C. L. (Participant), Staunstrup, N. H. (Participant) & Møller, B. K. (Participant)
Novo Nordisk Foundation, NEYE-Fonden
01/09/2022 → 31/12/2026
Project: Research
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DCCC Dansk forskningscenter for cirkulerende tumor DNA guided kræftbehandling - støttet af Kræftens Bekæmpelse
Andersen, C. L. (PI)
01/01/2020 → 31/12/2025
Project: Research
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A Comprehensive analysis of different Methods for Bisulfite Conversion of Circulating cell-free DNA
Ørntoft, M.-B. W. (Participant), Bramsen, J. B. (Participant), Jensen, S. Ø. (Participant) & Andersen, C. L. (Participant)
01/01/2016 → 01/01/2017
Project: Research
Research output
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Circulating tumor DNA predicts recurrence and survival in patients with resectable gastric and gastroesophageal junction cancer
Iden, C. R., Mustafa, S. M., Øgaard, N., Henriksen, T., Jensen, S. Ø., Ahlborn, L. B., Egebjerg, K., Baeksgaard, L., Garbyal, R. S., Nedergaard, M. K., Achiam, M. P., Andersen, C. L. & Mau-Sørensen, M., Jan 2025, In: Gastric Cancer. 28, 1, p. 83-95 13 p., 154086.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access9 Citations (Scopus) -
Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancer
Taira, A., Aavikko, M., Katainen, R., Kaasinen, E., Välimäki, N., Ravantti, J., Ristimäki, A., Seppälä, T. T., Renkonen-Sinisalo, L., Lepistö, A., Tahkola, K., Mattila, A., Koskensalo, S., Mecklin, J.-P., Böhm, J., Bramsen, J. B., Andersen, C. L., Palin, K., Rajamäki, K. & Aaltonen, L. A. & 1 others, , 19 Jun 2025, In: Oncogene. 44, 22, p. 1718-1730 13 p., e1600200.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access2 Citations (Scopus) -
Early detection of ovarian cancer using cell-free DNA fragmentomes and protein biomarkers
Medina, J. E., Annapragada, A. V., Lof, P., Short, S., Bartolomucci, A. L., Mathios, D., Koul, S., Niknafs, N., Noe, M., Foda, Z. H., Bruhm, D. C., Hruban, C., Vulpescu, N. A., Jung, E., Dua, R., Canzoniero, J. V., Cristiano, S., Adleff, V., Symecko, H. & van den Broek, D. & 15 others, , 1 Jan 2025, In: Cancer Discovery. 15, 1, p. 105-118 14 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access15 Citations (Scopus) -
Erratum to “Virtual Tissue Microarrays for Validating Digital Biomarker Analysis in Colorectal Carcinoma” (Lab Invest 105(2025) 104098) (Laboratory Investigation (2025) 105(4), (S002368372500008X), (10.1016/j.labinv.2025.104098))
Jørgensen, M. M., Hamilton-Dutoit, S. J., Bramsen, J. B., Andersen, C. L. & Holm, I. E., May 2025, In: Laboratory Investigation. 105, 5, 104122.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Corrigendum › Research › peer-review
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Fostering the implementation of liquid biopsy in clinical practice: meeting report 2024 of the European Liquid Biopsy Society (ELBS)
Pantel, K., Alix-Panabières, C., Hofman, P., Stoecklein, N. H., Lu, Y. J., Lianidou, E., Giacomini, P., Koch, C., de Jager, V., Deans, Z. C., Fairley, J., Patton, S. J., Toledo, R. A., Schuuring, E., Heitzer, E., Hendrix, A., Ricklefs, F. L., Thakur, B. K., von Bubnoff, N. & Pierga, J. Y. & 8 others, , Dec 2025, In: Journal of Experimental and Clinical Cancer Research. 44, 1, 9 p., 156.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access3 Citations (Scopus)
Activities
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Plenary talk: ctDNA based detection of MRD in colorectal cancer, are we ready for implementation?
Andersen, C. L. (Lecturer)
22 May 2025 → 23 May 2025Activity: Presentations, memberships, employment, ownership and other activities › Lecture and oral contribution
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GUIDE.MRD General Assembly 2025
Andersen, C. L. (Participant)
6 May 2025Activity: Participating in or organising an event types › Participation in or organisation of workshop, seminar or course
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American Association of Cancer Research (AACR) Annual Meeting 2025
Andersen, C. L. (Participant)
25 Apr 2025 → 30 Apr 2025Activity: Participating in or organising an event types › Participation in or organisation af a conference
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Kræft-DNA i blodet – seneste nyt fra forskningen
Andersen, C. L. (Lecturer)
15 Apr 2025Activity: Presentations, memberships, employment, ownership and other activities › Lecture and oral contribution
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Medlem af Phd bedømmelsesudvalg
Andersen, C. L. (Presenter)
1 Apr 2025 → 30 Jun 2025Activity: Evaluation, external lectures and examination › Member of evaluation panel
Prizes
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William Nielsen Foundation honorary award for cancer research
Andersen, C. L. (Recipient), 26 Aug 2018
Prize: Prizes, scholarships, distinctions
Press/Media
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Ny metode gør måling af ctDNA langt mere følsom og kan endda spotte forstadier til kræft
14/07/2024
1 Media contribution
Press/Media: Press / Media
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Undersøgelse: Kunstig intelligens kan opdage forstadier til kræft
11/07/2024
1 Media contribution
Press/Media: Press / Media
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Dansk AI-teknologi vækker opsigt: Har potentiale til at udrydde kræft som sygdom
30/06/2024
1 Media contribution
Press/Media: Press / Media
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Danskere står bag banebrydende AI, der kan gøre kræftsygdom fortid
27/06/2024
1 Media contribution
Press/Media: Press / Media
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Courses
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Hvad er liquid biopsies og hvad kan de bruges til i personlig medicin
Andersen, C. L. 13/12/2021 → 13/12/2021
Course: Teaching
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Multistep tumorigenese og Molekylære aspekter ved colon cancer – relevans i forbindelse med diagnostik og behandling
Andersen, C. L. 15/11/2021 → 15/11/2021
Course: Teaching
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Ph.d.-kursus: The Biology and characteristic of circulating cell free DNA and circulating tumour DNA in health and disease
Andersen, C. L. 22/05/2023 → 23/05/2023
Course: Teaching
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The Biology and characteristic of circulating cell free DNA and circulating tumour DNA in health and disease
Andersen, C. L. 19/05/2021 → 20/05/2021
Course: Teaching
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Undersøgelse af cirkulerende tumor DNA i blod (liquid biopsies)
Hertz, J. M. & Andersen, C. L. 09/03/2022 → 11/03/2022
Course: Teaching