Chuanxu Yang

  1. 2019
  2. Published

    HYBRID NANOPARTICLE. / Yang, Chuanxu (Inventor); Le, Dang Quang Svend (Inventor).

    IPC No.: A61K 9/51 (2006.01), A61K 9/19 (2006.01). Patent No.: PCT/DK2018/050330. Dec 06, 2018.

    Research output: PatentResearch

  3. Published

    Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab‐DNA conjugates. / Liu, Tianqiang; Song, Ping; Märcher, Anders; Kjems, Jørgen; Yang, Chuanxu; Gothelf, Kurt Vesterager.

    In: ChemBioChem, Vol. 20, No. 8, 04.2019, p. 1014-1018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. / Song, Ping; Yang, Chuanxu; Thomsen, Jesper Skovhus; Dagnaes-Hansen, Frederik; Jakobsen, Maria; Bruel, Annemarie; Deleuran, Bent; Kjems, Jorgen.

    In: Molecular Therapy, Vol. 27, No. 8, 2019, p. 1424-1435.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. 2018
  6. Published

    Lipidoid-siRNA formulations promote gene silencing in differentiated and nondividing ARPE-19, primary porcine and human embryonic stem cell-derived retinal pigment epithelial cells. / Subrizi, Astrid; Yang, Chuanxu; Ilmarinen, Tanja; Skottman, Heli; Urtti, Arto; Kjems, Jorgen.

    2018. Abstract from Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, .

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  7. Published

    Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells. / Yang, Chuanxu; Gao, Shan; Song, Ping; Dagnæs-Hansen, Frederik; Jakobsen, Maria Vad; Kjems, Jørgen.

    In: A C S Applied Materials and Interfaces, Vol. 10, No. 23, 13.06.2018, p. 19494–19503.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Calcium-microRNA Complexes Functionalized Nanotubular Implant Surface for Highly Efficient Transfection and Enhanced Osteogenesis of Mesenchymal Stem Cells. / Song, Wen; Yang, Chuanxu; Svend Le, Dang Quang; Zhang, Yumei; Kjems, Jørgen.

    In: A C S Applied Materials and Interfaces, Vol. 10, No. 9, 07.03.2018, p. 7756-7764.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2017
  10. Published

    Theranostic poly(lactic-co-glycolic acid) nanoparticle for magnetic resonance/infrared fluorescence bimodal imaging and efficient siRNA delivery to macrophages and its evaluation in a kidney injury model. / Yang, Chuanxu; Vu Quang, Hieu; Husum, Dina Michelle Unnerup; Tingskov, Stine Julie Hyldal; Vinding, Mads Sloth; Nielsen, Thomas; Song, Ping; Nielsen, Niels Christian; Nørregaard, Rikke; Kjems, Jørgen.

    In: Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 13, No. 8, 11.2017, p. 2451–2462.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Autophagy plays a dual role during intracellular siRNA delivery by lipoplex and polyplex nanoparticles. / Song, Wen; Ma, Zhiwei; Zhang, Yumei; Yang, Chuanxu.

    In: Acta Biomaterialia, Vol. 58, 08.2017, p. 196-204.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Impact of PEG Chain Length on the Physical Properties and Bioactivity of PEGylated Chitosan/siRNA Nanoparticles in Vitro and in Vivo. / Yang, Chuanxu; Gao, Shan; Dagnæs-Hansen, Frederik; Jakobsen, Maria; Kjems, Jørgen.

    In: A C S Applied Materials and Interfaces, Vol. 9, No. 14, 12.04.2017, p. 12203-12216.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. 2015
  14. Published

    Co-delivery of siRNA and doxorubicin to cancer cells from additively manufactured implants. / Chen, Muwan; Andersen, Morten Østergaard; Dillschneider, Philipp; Chang, Chi-Chih (Clare); Gao, Shan; Le, Dang Quang Svend; Yang, Chuanxu; Hein, San; Bünger, Cody; Kjems, Jørgen.

    In: RSC Advances, Vol. 5, 16.11.2015, p. 101718-101725.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Theranostic carbon dots derived from garlic with efficient anti-oxidative effects towards macrophages. / Yang, Chuanxu; Ogaki, Ryosuke; Hansen, Line; Kjems, Jørgen; Mian Teo, Boon.

    In: R S C Advances, Vol. 118, 09.11.2015, p. 97836-97840.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Serum-induced degradation of 3D DNA box origami observed with high-speed atomic force microscopy (vol 8, pg 2170, 2015). / Jiang, Zaixing; Zhang, Shuai; Yang, Chuanxu; Zadegan, Reza M.; Kjems, Jorgen; Huang, Yudong; Besenbacher, Flemming; Dong, Mingdong.

    In: Nano Research, Vol. 8, No. 10, 10.2015, p. 3446-3446.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Enhanced efficacy of chemotherapy for breast cancer stem cells by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense. / Sun, Ming; Yang, Chuanxu; Zheng, Jin; Wang, Miao; Chen, Muwan; Le, Dang Quang Svend; Kjems, Jørgen; Bünger, Cody.

    In: Acta Biomaterialia, Vol. 28, 28.09.2015, p. 171–182.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Macrophage-mediated nanoparticle delivery to the periodontal lesions in established murine model via Pg-LPS induction. / Ma, Zhiwei; Dagnaes-Hansen, Frederik; Løvschall, Henrik; Song, Wen; Nielsen, Gitte K; Yang, Chuanxu; Wang, Qintao; Kjems, Jørgen; Gao, Shan.

    In: Journal of Oral Pathology & Medicine, Vol. 44, No. 7, 08.2015, p. 538-542.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Serum induced degradation of 3D DNA box origami observed by high speed atomic force microscope. / Jiang, Zaixing; Zhang, Shuai; Yang, Chuanxu; Kjems, Jørgen; Huang, Yudong; Besenbacher, Flemming; Dong, MD.

    In: Nano Research, Vol. 8, No. 7, 07.2015, p. 2170-2178.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Ultrastable green fluorescence carbon dots with a high quantum yield for bioimaging and use as theranostic carriers. / Yang, Chuanxu; Thomsen, Rasmus Peter; Ogaki, Ryosuke; Kjems, Jørgen; Mian Teo, Boon.

    In: Journal of Materials Chemistry B, Vol. 3, No. 4577, 14.06.2015, p. 4577-4584.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion. / Song, Wen; Song, Xin; Yang, Chuanxu; Gao, Shan; Klausen, Lasse Hyldgaard; Zhang, Yumei; Dong, Mingdong; Kjems, Jorgen.

    In: International Journal of Nanomedicine (Online), Vol. 10, 2015, p. 2335-2346.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2014
  23. Published

    Folic Acid Conjugated Chitosan for Targeted Delivery of siRNA to Activated Macrophages in vitro and in vivo. / Yang, Chuanxu; Gao, Shan; Kjems, Jørgen.

    In: Journal of Materials Chemistry B, Vol. 48, 10.2014, p. 8608-8615.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Treatment of Chronic Kidney Disease with Sirna Nanoparticles Targeting MMP-2. / Pedersen, Lea Hougaard; Kellenberger, Terese; Yang, Chuanxu; Gao, Shan; Kjems, Jørgen; Wogensen, Lise.

    Program and Abstract Book. The Netherlands, 2014. p. 158-158.

    Research output: Contribution to book/anthology/report/proceedingConference abstract in proceedingsResearch

  25. Published

    Chitosan Hydrogel as siRNA vector for prolonged gene silencing. / Ma, Zhiwei; Yang, Chuanxu; Song, Wen; Wang, Qintao; Kjems, Jørgen; Gao, Shan.

    In: Journal of Nanobiotechnology, Vol. 12, No. 23, 19.06.2014, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans. / Munksgaard, Peter Svenssen; Skals, Marianne Gerberg; Reinholdt, Jesper; Poulsen, Knud; Jensen, Maria Risager; Yang, Chuanxu; Leipziger, Jens; Vorup-Jensen, Thomas; Praetorius, Helle A.

    In: Infection and Immunity, Vol. 82, No. 6, 06.2014, p. 2219-28.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice. / Yang, Chuanxu; Nilsson, Line; Cheema, Muhammad Umar; Wang, Yan; Frøkiær, Jørgen; Gao, Shan; Kjems, Jørgen; Nørregaard, Rikke.

    In: Theranostics, Vol. 5, No. 2, 2014, p. 110-123.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing. / Gao, Shan; Hein, San; Dagnæs-Hansen, Frederik; Weyer, Kathrin; Yang, Chuanxu; Nielsen, Rikke; Christensen, Erik I; Fenton, Robert A; Kjems, Jørgen.

    In: Theranostics, Vol. 4, No. 10, 2014, p. 1039-51.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Nanoparticle-Based Delivery System for Biomedical Applications of RNAi. / Yang, Chuanxu.

    Interdisciplinary Nanoscience Center (iNANO), Aarhus University, 2014. 198 p.

    Research output: Book/anthology/dissertation/reportPh.D. thesisResearch

  30. Published

    The influence of crystallite size and crystallinity of anatase nanoparticles on the photo-degradation of phenol. / Wang, Xueqin; Sø, Lasse Ugilt; Su, Ren; Wendt, Stefan; Hald, Peter; Mamakhel, Mohammad Aref Hasen; Yang, Chuanxu; Huang, Yudong; Iversen, Bo Brummerstedt; Besenbacher, Flemming.

    In: Journal of Catalysis, Vol. 310, 2014, p. 100-108.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. 2013
  32. Published

    Differential effects of Smad3 targeting in a murine model of chronic kidney disease. / Kellenberger, Terese; Krag, Søren; Danielsen, Carl Christian; Wang, Xiao-Fan; Nyengaard, Jens Randel; Pedersen, Lea Hougaard; Yang, Chuanxu; Gao, Shan; Wogensen, Lise.

    In: Physiological Reports, Vol. 1, No. 7, e00181, 01.12.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Self-assembled nanoparticles of modified-chitosan conjugates for the sustained release of dl-α-tocopherol. / Quinones, Javier Perez; Gothelf, Kurt Vesterager; Kjems, Jørgen; Yang, Chuanxu; Caballero, Angeles Maria Heras; Schmidt, Claudia; Peniche Covas, Carlos.

    In: Carbohydrate Polymers, Vol. 92, No. 1, 30.01.2013, p. 856-864.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Peritoneal macrophages mediated delivery of chitosan/siRNA nanoparticle to the lesion site in a murine radiation-induced fibrosis model. / Nawroth, Isabel; Alsner, Jan; Deleuran, B.W.; Dagnæs-Hansen, Frederik; Yang, Chuanxu; Horsman, Michael Robert; Overgaard, Jens; Howard, Ken; Kjems, Jørgen; Gao, Shan.

    In: Acta Oncologica, Vol. 52, No. 8, 01.01.2013, p. 1730-1738.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Optimized siRNA-PEG Conjugates for Extended Blood Circulation and Reduced Urine Excretion in Mice. / Iversen, Frank; Yang, Chuanxu; Dagnæs-Hansen, Frederik; Schaffert, David H; Kjems, Jørgen; Gao, Shan.

    In: Theranostics, Vol. 3, No. 3, 2013, p. 201-209.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. 2012
  37. Published

    Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery. / Chen, Menglin; Gao, Shan; Dong, Mingdong; Song, Jie; Yang, Chuanxu; Howard, Kenneth Alan; Kjems, Jørgen; Besenbacher, Flemming.

    In: A C S Nano, Vol. 6, No. 6, 26.06.2012, p. 4835-4844.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review