Research output per year
Research output per year
- 37 results
Search results
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2025
Exploring the association between familial hemiplegic migraine genes (CACNA1A, ATP1A2 and SCN1A) with migraine and epilepsy: A UK Biobank exome-wide association study
Staehr, C., Nyegaard, M., Bach, F. W., Rohde, P. D. & Matchkov, V. V., Jan 2025, In: Cephalalgia : an international journal of headache. 45, 1, p. 3331024241306103Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Hypoxia and ischemic stroke modify cerebrovascular tone by upregulating endothelial BK(Ca) channels—Lessons from rat, pig, mouse, and human
Staehr, C., Hinkley, V., Matchkov, V. V., Rajanathan, R., Hansen, L. M. B., Eiby, Y., Luque, N., Wright, I., Bjorkman, S. T., Miller, S. M., Grimley, R. S., Dettrick, A., Chand, K., Nguyen, H. L., Jones, N. M., Murphy, T. V. & Sandow, S. L., Apr 2025, In: Acta Physiologica (Print). 241, 4, e70030.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Pharmacological Interventions for the Acute Treatment of Hyperkalaemia: A Systematic Review and Meta-analysis
International Liaison Committee on Resuscitation ILCOR Advanced Paediatric Life Support Task Forces, Mar 2025, In: Resuscitation. 208, p. 110489 110489.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Open Access1 Citation (Scopus) -
SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling
Staehr, C., Login, H., Melnikova, E., Bakun, M., Ziemlinska, E., Kisiswa, L., Berenji Ardestani, S., Nolte, S. S., Beck, H. C., Hansen, L. M. B., Postnov, D., Verkhratsky, A., Malik, A. R., Nykjær, A. & Matchkov, V., 8 May 2025, In: Acta Physiologica (Print). 241, 6Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations
Hansen, L. M. B., Dam, V. S., Guldbrandsen, H. Ø., Staehr, C., Pedersen, T. M., Kalucka, J. M., Beck, H. C., Postnov, D., Lin, L. & Matchkov, V., 1 Apr 2025, In: Stroke. 56, 4, p. 1036-1047 12 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access -
Spinal cord blood flow elevation with systemic vasopressor noradrenaline is partly mediated by vasodilation of spinal arteries due to reduced expression of alpha adrenoreceptors
Entezari, S., Thygesen, M. M., Staehr, C., Melnikova, E., Skov, M., Rajanathan, R., Rasmussen, M., Rasmussen, M. M. & Matchkov, V. V., Mar 2025, In: The spine journal : official journal of the North American Spine Society. 25, 3, p. 609-619 11 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access1 Citation (Scopus) -
2024
Targeting Na,K-ATPase-Src signaling to normalize cerebral blood flow in a murine model of familial hemiplegic migraine
Staehr, C., Guldbrandsen, H. Ø., Homilius, C., Johnsen, L. Ø., Postnov, D., Pedersen, T. M., Pierre, S., Sandow, S. L. & Matchkov, V. V., 4 Dec 2024, (E-pub / Early view) In: Journal of Cerebral Blood Flow and Metabolism. p. 271678X241305562Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
1 Citation (Scopus) -
2023
Hypercontractile Cardiac Phenotype in Mice with Migraine-Associated Mutation in the Na+,K+-ATPase α2-Isoform
Rajanathan, R., Riera, C. V. I., Pedersen, T. M., Staehr, C., Bouzinova, E. V., Nyengaard, J. R., Thomsen, M. B., Bøtker, H. E. & Matchkov, V. V., Apr 2023, In: Cells. 12, 8, 21 p., 1108.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access1 Citation (Scopus) -
Hypoxia and ischemic stroke induce endothelial BKCa expression in cerebral arteries-a target for therapy?
Hinkley, V., Staehr, C., Matchkov, V., Rajanathan, R., Eiby, Y., Luque, N., Wright, I. J., Chand, K., Nguyen, H., Jones, N., Sandow, S. L. & Murphy, T., 11 Jun 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, S1, p. S84-S197Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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Neurovascular Uncoupling Is Linked to Microcirculatory Dysfunction in Regions Outside the Ischemic Core Following Ischemic Stroke
Staehr, C., Giblin, J. T., Gutiérrez-Jiménez, E., Guldbrandsen, H. Ø., Tang, J., Sandow, S. L., Boas, D. A. & Matchkov, V., Jun 2023, In: Journal of the American Heart Association. 12, 11, e029527.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access17 Citations (Scopus) -
SorCS2 modulates neurovascular coupling via glutamatergic and calcium signaling in astrocytes
Staehr, C., Login, H., Postnov, D., Berenji Ardestani, S., Nolte, S. S., Beck, H. C., Nykjær, A. & Matchkov, V., 16 Feb 2023, bioRxiv.Research output: Working paper/Preprint › Preprint
Open Access -
The vascular Na,K-ATPase: clinical implications in stroke, migraine, and hypertension
Staehr, C., Aalkjær, C. & Matchkov, V., Oct 2023, In: Clinical Science. 137, 20, p. 1595–1618 24 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review
Open AccessFile12 Citations (Scopus)12 Downloads (Pure) -
2022
Microcirculatory dysfunction associates with neurovascular uncoupling in peri-ischemic brain regions after ischemic stroke
Staehr, C., Giblin, J. T., Gutiérrez-Jiménez, E., Guldbrandsen, H. Ø., Tang, J., Sandow, S. L., Boas, D. A. & Matchkov, V., 26 Aug 2022, bioRxiv.Research output: Working paper/Preprint › Preprint
Open Access -
Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function
Staehr, C., Rohde, P. D., Krarup, N. T., Ringgaard, S., Laustsen, C., Johnsen, J., Nielsen, R., Beck, H. C., Morth, J. P., Lykke-Hartmann, K., Jespersen, N. R., Abramochkin, D., Nyegaard, M., Bøtker, H. E., Aalkjaer, C. & Matchkov, V., Apr 2022, In: Journal of the American Heart Association. 11, 7, 47 p., e021814.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access12 Citations (Scopus) -
Stress adaptation in rats associate with reduced expression of cerebrovascular Kv7.4 channels and biphasic neurovascular responses
Staehr, C., Bouzinova, E., Wiborg, O. & Matchkov, V., 6 Jun 2022, In: Stress: The International Journal on the Biology of Stress . 25, 1, p. 227-234 8 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access3 Citations (Scopus) -
2021
Demand creates its own supply: The Na/K-ATPase controls metabolic reserve and flexibility
Staehr, C. & Matchkov, V., Jul 2021, In: Acta Physiologica. 232, 3, 2 p., e13673.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Editorial › peer-review
Open Access3 Citations (Scopus) -
Does Src Kinase Mediated Vasoconstriction Impair Penumbral Reperfusion?
Guldbrandsen, H. Ø., Staehr, C., Iversen, N. K., Postnov, D. & Matchkov, V., 1 Jun 2021, In: Stroke. 52, 6, p. E250-E258 9 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review
6 Citations (Scopus) -
2020
Abnormal neurovascular coupling as a cause of excess cerebral vasodilation in familial migraine
Staehr, C., Rajanathan, R., Postnov, D., Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Bach, F. W., Sandow, S. L., Aalkjær, C. & Matchkov, V., 1 Oct 2020, In: Cardiovascular Research. 116, 12, p. 2009-2020 12 p., cvz306.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
20 Citations (Scopus) -
PTPRG is an ischemia risk locus essential for HCO3--dependent regulation of endothelial function and tissue perfusion
Berg-Hansen, K., Staehr, C., Rohde, P. D., Homilius, C., Kim, S., Nyegaard, M., Matchkov, V. & Boedtkjer, E., Sept 2020, In: eLife. 9, p. 1-46 26 p., e57553.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access15 Citations (Scopus) -
2019
[Ca2+] changes in sympathetic varicosities and Schwann cells in rat mesenteric arteries—Relation to noradrenaline release and contraction
Hansen, T., Tarasova, O. S., Khammy, M. M., Ferreira, A., A. Kennard, J., Andresen, J., Staehr, C., L. Brain, K., Nilsson, H. & Aalkjær, C., Aug 2019, In: Acta Physiologica. 226, 4, 11 p., e13279.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
9 Citations (Scopus) -
Abnormal neurovascular signaling in mouse model for familial hemiplegic migraine type 2
Matchkov, V., Staehr, C., Rajanathan, R., Postnov, D., Bouzinova, E. V., Lykke-Hartmann, K. & Aalkjær, C., 1 Apr 2019, In: The FASEB Journal. 33, p. 688.14 - 688.14Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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An abundance of the Na,K-ATPase modulates homeostasis of blood glucose.
Matchkov, V. V., Duy, N. T., Rajanathan, R., Jeppesen, P. B., Bouzinova, E. & Staehr, C., 2019, p. 134-134. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Involvement of the Na + ,K +-ATPase isoforms in control of cerebral perfusion
Staehr, C., Rajanathan, R. & Matchkov, V. V., 2019, In: Experimental Physiology. 104, 7, p. 1023-1028 6 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
11 Citations (Scopus) -
Migraine-associated mutation in the a2 isoform Na,K-ATPase is associated with cardiomyopathy-like changes in the mouse heart
Bouzinova, E., Lykke-Hartmann, K., Nyengaard, J. R., Beck, H. C., Matchkov, V. & Staehr, C., 1 Nov 2019, In: Acta Physiologica (Print). 227, S721Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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Smooth muscle Ca2+ sensitization causes hypercontractility of middle cerebral arteries in mice bearing the familial hemiplegic migraine type 2 associated mutation
Staehr, C., Hangaard, L., Bouzinova, E. V., Kim, S., Rajanathan, R., Boegh Jessen, P., Luque, N., Xie, Z., Lykke-Hartmann, K., Sandow, S. L., Aalkjær, C. & Matchkov, V. V., Aug 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 8, p. 1570-1587 18 p., 0271678X18761712.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access26 Citations (Scopus) -
The Na,K-ATPase in vascular smooth muscle cells
Zhang, L., Staehr, C., Zeng, F., Bouzinova, E. V. & Matchkov, V. V., Jan 2019, Membrane transporters in the pathogenesis of cardiovascular and lung disorders. Orlov, S. N. (ed.). Cambridge, MA: Academic Press, p. 151-175 (Current Topics in Membranes, Vol. 83).Research output: Contribution to book/anthology/report/proceeding › Review
11 Citations (Scopus) -
Upregulation of Endothelial Kir2. 1 Channel Disturbs Neurovascular Coupling in Familial Hemiplegic Migraine
Staehr, C., Rajanathan, R. & Matchkov, V., 1 Nov 2019, In: Acta Physiologica (Print). 227, S721, p. 121-121 1 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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2018
Migraine associated mutation in the α2 isoform Na+,K+-ATPase leads to disturbance in neurovascular coupling
Staehr, C., Rajanathan, R., Bouzinova, E., Aalkjær, C., Bach, F. W. & Matchkov, V., 2018, In: Proc. Physiol. Soc.. 41, SA066Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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The α2 isoform Na,K-ATPase modulates contraction of rat mesenteric small artery via cSrc–dependent Ca2+ sensitization
Bouzinova, E., Hangaard, L., Staehr, C., Mazur, A., Chibalin, A. V., Sandow, S. L., Xie, Z., Aalkjær, C. & Matchkov, V., Sept 2018, In: Acta Physiologica. 223, 1, p. e13059 e13059.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
17 Citations (Scopus) -
2017
Dysfunctional neurovascular coupling in familial hemiplegic migraine type 2
Staehr, C., Bouzinova, E., Lykke, K., Aalkjær, C. & Matchkov, V., 1 Feb 2017, In: Acta Physiologica (Print). 219, p. 8-9 2 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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Intravital investigation of rat mesenteric small artery tone and blood flow
Nyvad, J., Mazur, A., Postnov, D. D., Straarup, M. S., Soendergaard, A. M., Staehr, C., Brøndum, E., Aalkjaer, C. & Matchkov, V. V., 1 Aug 2017, In: The Journal of Physiology. 595, 15, p. 5037-5053 17 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
25 Citations (Scopus) -
Na,K-ATPase regulates intercellular communication in the vascular wall via cSrc kinase dependent connexin43 phosphorylation.
Hangaard, L., Bouzinova, E., Stæhr, C. A., Dam, V. S., Kim, S., Xie, Z., Aalkjær, C. & Matchkov, V., 7 Apr 2017, In: American Journal of Physiology: Cell Physiology. 4, 312, p. C385-C397 13 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open Access21 Citations (Scopus) -
2016
An associated with Familial Hemiplegic Migraine Type 2 mutation in the alpha-2 isoform Na,K-ATPase disturbs vascular responses in mouse brain
Staehr, C., Hangaard, L., Lykke-Hartmann, K., Bouzinova, E., Aalkjær, C. & Matchkov, V., 2016, In: Artery Research. 16, 1Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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Dysfunctional neurovascular coupling in Familial hemiplegic migraine type 2
Staehr, C., Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Aalkjær, C. & Matchkov, V., 2016, In: High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension. 23Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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2015
Pro-contractile action of the Na,K-ATPase/Src-kinase signaling pathway in the vascular wall.
Bouzinova, E., Hangaard, L., Xie, Z., Staehr, C., Aalkjær, C. & Matchkov, V., 28 Aug 2015. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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The α2 Isoform of Na,K-ATPase Modulates Vascular Tone via Activation of Src kinase (Src) Signalling Pathway: a Lesion from Mouse Model for Familial Hemiplegic Migraine Type 2 (FHM2)
Matchkov, V., Hangaard, L., Staehr, C., Lykke-Hartmann, K., Xie, Z. & Aalkjær, C., 2015, In: The FASEB Journal. 29, 844.818Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
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α1-,α2-Na,K-ATPase and Kir 2.1 expression and their implications for cerebral artery function and migraine etiology in a mouse model of Familial Hemiplegic Migraine type 2
Sandow, S. L., Hinkley, V., Lykke-Hartmann, K., Hangaard, L., Staehr, C., Aalkjær, C. & Matchkov, V., 2015, In: Proceedings of the Australian Physiological Society. 46Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review
Open Access