Christoffer Laustsen

Professor

Christoffer Laustsen
Department of Clinical Medicine - The MR Research Centre
Brendstrupgårdsvej 100
8200, Aarhus N
Denmark
E-mail: cl@mr.au.dk
Phone: 78456106

Publications

Laustsen, C, Nielsen, PM, Qi, H, Løbner, MH, Palmfeldt, J & Bertelsen, LB 2020, 'Hyperpolarized [1,4-13C]fumarate imaging detects microvascular complications and hypoxia mediated cell death in diabetic nephropathy', Scientific Reports, vol. 10, 9650. https://doi.org/10.1038/s41598-020-66265-6
de Boer, A, Villa, G, Bane, O, Bock, M, Cox, EF, Dekkers, IA, Eckerbom, P, Fernández-Seara, MA, Francis, ST, Haddock, B, Hall, ME, Hall Barrientos, P, Hermann, I, Hockings, PD, Lamb, HJ, Laustsen, C, Lim, RP, Morris, DM, Ringgaard, S, Serai, SD, Sharma, K, Sourbron, S, Takehara, Y, Wentland, AL, Wolf, M, Zöllner, FG, Nery, F & Caroli, A 2020, 'Consensus-Based Technical Recommendations for Clinical Translation of Renal Phase Contrast MRI', Journal of Magnetic Resonance Imaging. https://doi.org/10.1002/jmri.27419
Bøgh, N, Søvsø Szocska Hansen, E, Østergaard Mariager, C, Bertelsen, LB, Ringgaard, S & Laustsen, C 2020, 'Cardiac pH-Imaging With Hyperpolarized MRI', Frontiers in cardiovascular medicine, vol. 7, 603674. https://doi.org/10.3389/fcvm.2020.603674
Mariager, CØ, Hansen, ESS, Bech, SK, Munk, A, Kjærgaard, U, Lyhne, MD, Søberg, K, Nielsen, PF, Ringgaard, S & Laustsen, C 2020, 'Graft assessment of the ex vivo perfused porcine kidney using hyperpolarized [1-13C]pyruvate', Magnetic Resonance in Medicine, vol. 84, no. 5, pp. 2645-2655. https://doi.org/10.1002/mrm.28363
Grist, JT, Riemer, F, Hansen, E, Tougaard, RS, McLean, MA, Kaggie, J, Bøgh, N, Graves, MJ, Gallagher, FA & Laustsen, C 2020, 'Visualization of sodium dynamics in the kidney by magnetic resonance imaging in a multi-site study', Kidney International, vol. 98, no. 5, pp. 1174-1178. https://doi.org/10.1016/j.kint.2020.04.056
Nielsen, PM, Mariager, CØ, Mølmer, M, Sparding, N, Genovese, F, Karsdal, MA, Nørregaard, R, Bertelsen, LB & Laustsen, C 2020, 'Hyperpolarized [1-13C] alanine production: A novel imaging biomarker of renal fibrosis', Magnetic Resonance in Medicine, vol. 84, no. 4, pp. 2063-2073. https://doi.org/10.1002/mrm.28326
Lindhardt, JL, Nielsen, PM, Hansen, ESS, Qi, H, Tougaard, RS, Mariager, CØ, Bertelsen, LB, Kim, WY & Laustsen, C 2020, 'The hemodynamic and metabolic effects of spironolactone treatment in acute kidney injury assessed by hyperpolarized MRI', NMR in Biomedicine, vol. 33, no. 10, e4371. https://doi.org/10.1002/nbm.4371
van Erp, AC, Qi, H, Jespersen, NR, Hjortbak, MV, Ottens, PJ, Wiersema-Buist, J, Nørregaard, R, Pedersen, M, Laustsen, C, Leuvenink, HGD & Jespersen, B 2020, 'Organ-specific metabolic profiles of the liver and kidney during brain death and afterwards during normothermic machine perfusion of the kidney', American Journal of Transplantation, vol. 20, no. 9, pp. 2425-2436. https://doi.org/10.1111/ajt.15885
Grist, JT, Mariager, CØ, Qi, H, Nielsen, PM & Laustsen, C 2020, 'Detection of acute kidney injury with hyperpolarized [13C, 15N]Urea and multiexponential relaxation modeling', Magnetic Resonance in Medicine, vol. 84, no. 2, pp. 943-949. https://doi.org/10.1002/mrm.28134
Nielsen, PM, Mariager, CØ, Rasmussen, DGK, Mølmer, M, Genovese, F, Karsdal, MA, Laustsen, C & Nørregaard, R 2020, 'Noninvasive Assessment of Fibrosis Following Ischemia/Reperfusion Injury in Rodents Utilizing Na Magnetic Resonance Imaging', Pharmaceutics, vol. 12, no. 8, 775. https://doi.org/10.3390/pharmaceutics12080775
Riis-Vestergaard, MJ, Laustsen, C, Mariager, CØ, Schulte, RF, Pedersen, SB & Richelsen, B 2020, 'Glucose metabolism in brown adipose tissue determined by deuterium metabolic imaging in rats', International journal of obesity (2005), vol. 44, no. 6, pp. 1417-1427. https://doi.org/10.1038/s41366-020-0533-7
Nielsen, PM, Qi, H, Bertelsen, LB & Laustsen, C 2020, 'Metabolic reprogramming associated with progression of renal ischemia reperfusion injury assessed with hyperpolarized [1-13C]pyruvate', Scientific Reports, vol. 10, 8915. https://doi.org/10.1038/s41598-020-65816-1
Bøgh, N, Søvsø Szocska Hansen, E, Omann, C, Lindhardt, JL, Nielsen, PM, Stephenson, RS, Laustsen, C, Hjortdal, VE & Agger, P 2020, 'Increasing carbohydrate oxidation improves contractile reserves and prevents hypertrophy in porcine right heart failure', Scientific Reports, vol. 10, 8158. https://doi.org/10.1038/s41598-020-65098-7
Agger, P, Omann, C, Laustsen, C, Stephenson, RS & Anderson, RH 2020, 'Anatomically correct assessment of the orientation of the cardiomyocytes using diffusion tensor imaging', NMR in Biomedicine, vol. 33, no. 3, e4205. https://doi.org/10.1002/nbm.4205
Wen, Y, Qi, H, Østergaard Mariager, C, Mose Nielsen, P, Bonde Bertelsen, L, Stødkilde-Jørgensen, H & Laustsen, C 2020, 'Sex Differences in Kidney Function and Metabolism Assessed Using Hyperpolarized [1-13C]Pyruvate Interleaved Spectroscopy and Nonspecific Imaging', Tomography - A Journal for Imaging Research, vol. 6, no. 1, pp. 5-13. https://doi.org/10.18383/j.tom.2020.00022
Nery, F, Buchanan, CE, Harteveld, AA, Odudu, A, Bane, O, Cox, EF, Derlin, K, Gach, HM, Golay, X, Gutberlet, M, Laustsen, C, Ljimani, A, Madhuranthakam, AJ, Pedrosa, I, Prasad, PV, Robson, PM, Sharma, K, Sourbron, S, Taso, M, Wang, DJJ, Zhang, JL, Alsop, DC, Fain, SB, Francis, ST & Fernández-Seara, MA 2020, 'Consensus-based technical recommendations for clinical translation of renal ASL MRI', Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 33, no. 1, pp. 141-161. https://doi.org/10.1007/s10334-019-00800-z
Mendichovszky, I, Pullens, P, Dekkers, I, Nery, F, Bane, O, Pohlmann, A, de Boer, A, Ljimani, A, Odudu, A, Buchanan, C, Sharma, K, Laustsen, C, Harteveld, A, Golay, X, Pedrosa, I, Alsop, D, Fain, S, Caroli, A, Prasad, P, Francis, S, Sigmund, E, Fernández-Seara, M & Sourbron, S 2020, 'Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA', Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 33, no. 1, pp. 131-140. https://doi.org/10.1007/s10334-019-00784-w
Agger, P, Hyldebrandt, JA, Hansen, ESS, Omann, C, Bøgh, N, Waziri, F, Nielsen, PM & Laustsen, C 2020, 'Magnetic resonance hyperpolarization imaging detects early myocardial dysfunction in a porcine model of right ventricular heart failure', European Heart Journal Cardiovascular Imaging, vol. 21, no. 1, pp. 93-101. https://doi.org/10.1093/ehjci/jez074
Sánchez-Heredia, JD, Baron, R, Hansen, ESS, Laustsen, C, Zhurbenko, V & Ardenkjaer-Larsen, JH 2020, 'Autonomous cryogenic RF receive coil for 13C imaging of rodents at 3 T', Magnetic Resonance in Medicine, vol. 84, no. 1, pp. 497-508. https://doi.org/10.1002/mrm.28113
Ljimani, A, Caroli, A, Laustsen, C, Francis, S, Mendichovszky, IA, Bane, O, Nery, F, Sharma, K, Pohlmann, A, Dekkers, IA, Vallee, J-P, Derlin, K, Notohamiprodjo, M, Lim, RP, Palmucci, S, Serai, SD, Periquito, J, Wang, ZJ, Froeling, M, Thoeny, HC, Prasad, P, Schneider, M, Niendorf, T, Pullens, P, Sourbron, S & Sigmund, EE 2020, 'Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI', Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 33, no. 1, pp. 177-195. https://doi.org/10.1007/s10334-019-00790-y
Grist, JT, Hansen, ESS, Sánchez-Heredia, JD, McLean, MA, Tougaard, R, Riemer, F, Schulte, RF, Kaggie, JD, Ardenkjaer-Larsen, JH, Laustsen, C & Gallagher, FA 2020, 'Creating a clinical platform for carbon-13 studies using the sodium-23 and proton resonances', Magnetic Resonance in Medicine, vol. 84, no. 4, pp. 1817-1827. https://doi.org/10.1002/mrm.28238
Mariager, CØ, Hansen, ESS, Bech, SK, Eiskjær, H, Nielsen, PF, Ringgaard, S, Kimose, HH & Laustsen, C 2020, 'Development of a human heart-sized perfusion system for metabolic imaging studies using hyperpolarized [1-13C]pyruvate MRI', Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.28639
Sánchez-Heredia, JD, Olin, RB, McLean, MA, Laustsen, C, Hansen, AE, Hanson, LG & Ardenkjær-Larsen, JH 2020, 'Multi-site benchmarking of clinical 13C RF coils at 3T', Journal of Magnetic Resonance, vol. 318, 106798. https://doi.org/10.1016/j.jmr.2020.106798
Bøgh, N, Agger, P, Christensen, CO, Skov, MN, Laustsen, C, Wang, T & Pedersen, M 2020, 'New Device for Noninvasive Telemetric Monitoring of Vital Signs in Healthy and Newly Operated Piglets', Journal of the American Association for Laboratory Animal Science, vol. 59, no. 1, pp. 90-93. https://doi.org/10.30802/AALAS-JAALAS-19-000052
Olin, RB, Sánchez-Heredia, JD, Schulte, RF, Bøgh, N, Hansen, ESS, Laustsen, C, Hanson, LG & Ardenkjaer-Larsen, JH 2020, 'Three-dimensional accelerated acquisition for hyperpolarized 13C MR  with blipped stack-of-spirals and conjugate-gradient  SENSE', Magnetic Resonance in Medicine, vol. 84, no. 2, pp. 519-534. https://doi.org/10.1002/mrm.28171
Hansen, RB, Sánchez-Heredia, JD, Bøgh, N, Hansen, ESS, Laustsen, C, Hanson, LG & Ardenkjaer-Larsen, JH 2019, 'Coil profile estimation strategies for parallel imaging with hyperpolarized 13 C MRI', Magnetic Resonance in Medicine, vol. 82, no. 6, pp. 2104-2117. https://doi.org/10.1002/mrm.27892
Elbæk Madsen, K, Mariager, CØ, Duvald, CS, Hansen, ESS, Bertelsen, LB, Pedersen, M, Pedersen, LH, Uldbjerg, N & Laustsen, C 2019, 'Ex Vivo Human Placenta Perfusion, Metabolic and Functional Imaging for Obstetric Research-A Feasibility Study', Tomography - A Journal for Imaging Research, vol. 5, no. 4, pp. 333-338. https://doi.org/10.18383/j.tom.2019.00016
Omann, C, Agger, P, Bøgh, N, Laustsen, C, Ringgaard, S, Stephenson, RS, Anderson, RH, Hjortdal, VE & Smerup, M 2019, 'Resolving the natural myocardial remodelling brought upon by cardiac contraction; a porcine ex-vivo cardiovascular magnetic resonance study of the left and right ventricle', Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, vol. 21, 35. https://doi.org/10.1186/s12968-019-0547-2
Sanchez-Heredia, JD, Johansen, DH, Hansen, RB, Szocska Hansen, ES, Laustsen, C, Zhurbenko, V & Ardenkjaer-Larsen, JH 2019, 'Improved Decoupling for Low Frequency MRI Arrays using Non-conventional Preamplifier Impedance', IEEE transactions on bio-medical engineering, vol. 66, no. 7, 8533360, pp. 1940-1948. https://doi.org/10.1109/TBME.2018.2881203
Laustsen, C, Lipsø, K, Østergaard, JA, Nielsen, PM, Bertelsen, LB, Flyvbjerg, A, Pedersen, M, Palm, F & Ardenkjær-Larsen, JH 2019, 'High Intrarenal Lactate Production Inhibits the Renal Pseudohypoxic Response to Acutely Induced Hypoxia in Diabetes', Tomography - A Journal for Imaging Research, vol. 5, no. 2, pp. 239-247. https://doi.org/10.18383/j.tom.2019.00003
Tougaard, RS, Szocska Hansen, ES, Laustsen, C, Nørlinger, TS, Mikkelsen, E, Lindhardt, J, Nielsen, PM, Bertelsen, LB, Schroeder, M, Bøtker, HE, Kim, WY, Wiggers, H & Stødkilde-Jørgensen, H 2019, 'Hyperpolarized [1-13 C]pyruvate MRI can image the metabolic shift in cardiac metabolism between the fasted and fed state in a porcine model', Magnetic Resonance in Medicine, vol. 81, no. 4, pp. 2655-2665. https://doi.org/10.1002/mrm.27560
Faarkrog Høyer, K, Laustsen, C, Ringgaard, S, Qi, H, Mariager, CØ, Nielsen, TS, Sundekilde, UK, Treebak, JT, Jessen, N & Stødkilde-Jørgensen, H 2019, 'Assessment of mouse liver [1-13C]pyruvate metabolism by dynamic hyperpolarized MRS', Journal of Endocrinology, vol. 242, no. 3, pp. 251-260. https://doi.org/10.1530/JOE-19-0159
Mariager, CØ, Lindhardt, J, Nielsen, PM, Schulte, RF, Ringgaard, S & Laustsen, C 2019, 'Fractional Perfusion: A Simple Semi-Parametric Measure for Hyperpolarized C-13 MR', IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 3, no. 4, pp. 523-527. https://doi.org/10.1109/TRPMS.2019.2905724
Wang, Z, Nielsen, PM, Laustsen, C & Bertelsen, LB 2019, 'Metabolic consequences of lactate dehydrogenase inhibition by oxamate in hyperglycemic proximal tubular cells', Experimental Cell Research, vol. 378, no. 1, pp. 51-56. https://doi.org/10.1016/j.yexcr.2019.03.001
Kjaergaard, U, Laustsen, C, Nørlinger, T, Tougaard, RS, Mikkelsen, E, Qi, H, Bertelsen, LB, Jessen, N & Stødkilde-Jørgensen, H 2018, 'Hyperpolarized [1-13 C] pyruvate as a possible diagnostic tool in liver disease', Physiological Reports, vol. 6, no. 23, pp. e13943. https://doi.org/10.14814/phy2.13943
Qi, H, Mariager, CØ, Nielsen, PM, Schroeder, M, Lindhardt, J, Nørregaard, R, Klein, JD, Sands, JM & Laustsen, C 2018, 'Glucagon infusion alters the hyperpolarized 13 C-urea renal hemodynamic signature', NMR in Biomedicine, pp. e4028. https://doi.org/10.1002/nbm.4028
Tougaard, RS, Hansen, ESS, Laustsen, C, Lindhardt, J, Schroeder, M, Bøtker, HE, Kim, WY, Wiggers, H & Stødkilde-Jørgensen, H 2018, 'Acute hypertensive stress imaged by cardiac hyperpolarized [1-C]pyruvate magnetic resonance', Magnetic Resonance in Medicine, vol. 80, no. 5, pp. 2053-2061. https://doi.org/10.1002/mrm.27164
Miller, JJ, Lau, AZ, Nielsen, PM, McMullen-Klein, G, Lewis, AJ, Jespersen, NR, Ball, V, Gallagher, FA, Carr, CA, Laustsen, C, Bøtker, HE, Tyler, DJ & Schroeder, MA 2018, 'Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis', J A C C: Cardiovascular Imaging, vol. 11, no. 11, pp. 1594-1606. https://doi.org/10.1016/j.jcmg.2017.09.020
Shokouh, P, Jeppesen, PB, Hermansen, K, Laustsen, C, Stødkilde-Jørgensen, H, Hamilton-Dutoit, SJ, Søndergaard Schmedes, M, Qi, H, Stokholm Nørlinger, T & Gregersen, S 2018, 'Effects of Unfiltered Coffee and Bioactive Coffee Compounds on the Development of Metabolic Syndrome Components in a High-Fat-/High-Fructose-Fed Rat Model', Nutrients, vol. 10, no. 10. https://doi.org/10.3390/nu10101547
Miller, JJ, Grist, JT, Serres, S, Larkin, JR, Lau, AZ, Ray, K, Fisher, KR, Hansen, E, Tougaard, RS, Nielsen, PM, Lindhardt, J, Laustsen, C, Gallagher, FA, Tyler, DJ & Sibson, N 2018, '13C Pyruvate Transport Across the Blood-Brain Barrier in Preclinical Hyperpolarised MRI', Scientific Reports, vol. 8, no. 1, pp. 15082. https://doi.org/10.1038/s41598-018-33363-5
Riis-Vestergaard, MJ, Breining, P, Pedersen, SB, Laustsen, C, Stødkilde-Jørgensen, H, Borghammer, P, Jessen, N & Richelsen, B 2018, 'Evaluation of active brown adipose tissue by the use of hyperpolarized [1-13C]pyruvate MRI in mice', International Journal of Molecular Sciences, vol. 19, no. 9, 2597. https://doi.org/10.3390/ijms19092597
Lipsø, KW, Hansen, ESS, Tougaard, RS, Laustsen, C & Ardenkjaer-Larsen, JH 2018, 'Dynamic coronary MR angiography in a pig model with hyperpolarized water', Magnetic Resonance in Medicine, vol. 80, no. 3, pp. 1165-1169. https://doi.org/10.1002/mrm.27088
Bertelsen, LB, Nielsen, PM, Qi, H, Mariager, CØ, Lindhardt, J & Laustsen, C 2018, 'Renal Energy Metabolism Following Acute Dichloroacetate and 2,4-Dinitrophenol Administration: Assessing the Cumulative Action with Hyperpolarized [1-13C]Pyruvate MRI', Tomography - A Journal for Imaging Research, vol. 4, no. 3, pp. 105-109. https://doi.org/10.18383/j.tom.2018.00022
Mikkelsen, EFR, Mariager, CØ, Nørlinger, T, Qi, H, Schulte, RF, Jakobsen, S, Frøkiær, J, Pedersen, M, Stødkilde-Jørgensen, H & Laustsen, C 2018, 'Publisher Correction: Hyperpolarized [1-C]-acetate Renal Metabolic Clearance Rate Mapping', Scientific Reports, vol. 8, no. 1, pp. 11235. https://doi.org/10.1038/s41598-018-29057-7
Van Erp, AC, Rebolledo, RA, Hoeksma, D, Jespersen, NR, Ottens, PJ, Nørregaard, R, Pedersen, M, Laustsen, C, Burgerhof, JGM, Wolters, JC, Ciapaite, J, Bøtker, HE, Leuvenink, HGD & Jespersen, B 2018, 'Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys', Scientific Reports, vol. 8, no. 1, pp. 4405. https://doi.org/10.1038/s41598-018-22689-9
Qi, H, Mariager, CØ, Lindhardt, J, Nielsen, PM, Stødkilde-Jørgensen, H & Laustsen, C 2018, 'Effects of anesthesia on renal function and metabolism in rats assessed by hyperpolarized MRI', Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.27165
Liao, D, Gregersen, H, Agger, P, Laustsen, C, Ringgaard, S, Stødkilde-Jørgensen, H & Zhao, J 2018, '3D reconstruction and fiber quantification in the pig lower esophageal sphincter region using in vitro diffusion tensor imaging', Biomedical Physics & Engineering Express, vol. 4.
Shokouh, P, Jeppesen, PB, Hermansen, K, Nørskov, NP, Laustsen, C, Jacques Hamilton-Dutoit, S, Qi, H, Stødkilde-Jørgensen, H & Gregersen, S 2018, 'A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome', Nutrients, vol. 10, no. 1, 6. https://doi.org/10.3390/nu10010006
Qi, H, Nielsen, PM, Schroeder, M, Bertelsen, LB, Palm, F & Laustsen, C 2018, 'Acute renal metabolic effect of metformin assessed with hyperpolarised MRI in rats', Diabetologia, vol. 61, no. 2, pp. 445-454. https://doi.org/10.1007/s00125-017-4445-6
Mariager, CØ, Nielsen, PM, Qi, H, Ringgaard, S & Laustsen, C 2018, 'Hyperpolarized 13 C,15 N2 -urea T2 relaxation changes in acute kidney injury', Magnetic Resonance in Medicine, vol. 80, no. 2, pp. 696-702. https://doi.org/10.1002/mrm.27050
Agger, P, Ilkjær, C, Laustsen, C, Smerup, M, Frandsen, JR, Ringgaard, S, Pedersen, M, Partridge, JB, Anderson, RH & Hjortdal, V 2017, 'Changes in overall ventricular myocardial architecture in the setting of a porcine animal model of right ventricular dilation', Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, vol. 19, no. 1, pp. 93. https://doi.org/10.1186/s12968-017-0404-0
Mikkelsen, EFR, Mariager, CØ, Nørlinger, T, Qi, H, Schulte, RF, Jakobsen, S, Frøkiær, J, Pedersen, M, Stødkilde-Jørgensen, H & Laustsen, C 2017, 'Hyperpolarized [1-13C]-acetate Renal Metabolic Clearance Rate Mapping', Scientific Reports, vol. 7, no. 1, pp. 16002. https://doi.org/10.1038/s41598-017-15929-x
Wigh Lipsø, K, Hansen, ESS, Tougaard, RS, Laustsen, C & Ardenkjaer-Larsen, JH 2017, 'Renal MR angiography and perfusion in the pig using hyperpolarized water', Magnetic Resonance in Medicine, pp. 1131-1135. https://doi.org/10.1002/mrm.26478
Østergaard Mariager, C, Nielsen, PM, Qi, H, Schroeder, M, Bertelsen, LB & Laustsen, C 2017, 'Can hyperpolarized 13C-Urea be used to assess glomerular filtration rate? a retrospective study', Tomography - A Journal for Imaging Research, vol. 3, no. 3. <http://www.tomography.org/volume-3/issue-3-september/research-articles/j-tom-2017-00010>
Lauritzen, MH, Magnusson, P, Laustsen, C, Butt, SA, Ardenkjaer-Larsen, JH, Veje Søgaard, L, Paulson, OB & Åkeson, P 2017, 'Imaging regional metabolic changes in the ischemic rat heart in vivo using hyperpolarized(1-13C)Pyruvate', Tomography - A Journal for Imaging Research, vol. 3, no. 3, 3. <http://tomography.org/volume-3/issue-3-september/research-articles/j-tom-2017-00008>
Xu, Y, Ringgaard, S, Mariager, CØ, Bertelsen, LB, Schroeder, M, Qi, H, Laustsen, C & Stødkilde-Jørgensen, H 2017, 'Hyperpolarized C Magnetic Resonance Imaging Can Detect Metabolic Changes Characteristic of Penumbra in Ischemic Stroke', Tomography - A Journal for Imaging Research, vol. 3, no. 2, pp. 67-73. https://doi.org/10.18383/j.tom.2017.00106
Mellbye, FB, Jeppesen, PB, Shokouh, P, Laustsen, C, Hermansen, K & Gregersen, S 2017, 'Cafestol, a Bioactive Substance in Coffee, Has Antidiabetic Properties in KKAy Mice', Journal of Natural Products. https://doi.org/10.1021/acs.jnatprod.7b00395
Mikkelsen, E, Lauridsen, H, Nielsen, PM, Qi, H, Nørlinger, T, Andersen, MD, Uldbjerg, N, Laustsen, C, Sandager, P & Pedersen, M 2017, 'The chinchilla as a novel animal model of pregnancy', Royal Society Open Science, vol. 4, no. 4, pp. 161098. https://doi.org/10.1098/rsos.161098
Nørlinger, TS, Nielsen, PM, Qi, H, Mikkelsen, E, Hansen, K, Schmidt, NH, Pedersen, M, Agger, P, Palm, F & Laustsen, C 2017, 'Hyperbaric oxygen therapy reduces renal lactate production', Physiological Reports, vol. 5, no. 6. https://doi.org/10.14814/phy2.13217
Sanchez, JD, Søvsø Szocska Hansen, E, Laustsen, C, Zhurbenko, V & Ardenkjaer-Larsen, JH 2017, 'Low-Noise Active Decoupling Circuit and its Application to 13C Cryogenic RF Coils at 3T', Tomography - A Journal for Imaging Research, vol. 3, no. 1, pp. 60-66. https://doi.org/10.18383/j.tom.2016.00280
Schroeder, M & Laustsen, C 2017, 'Imaging oxygen metabolism with hyperpolarized magnetic resonance: a novel approach for cardiac and renal function assessement', Bioscience Reports. https://doi.org/10.1042/BSR20160186
Nielsen, PM, Eldirdiri, A, Bertelsen, LB, Jørgensen, HS, Ardenkjaer-Larsen, JH & Laustsen, C 2017, 'Fumarase activity: an in vivo and in vitro biomarker for acute kidney injury', Scientific Reports, vol. 7, pp. 40812. https://doi.org/10.1038/srep40812
Laustsen, C, Nielsen, PM, Nørlinger, TS, Qi, H, Pedersen, UK, Bertelsen, LB, Østergaard, JA, Flyvbjerg, A, Ardenkjær-Larsen, JH, Palm, F & Stødkilde-Jørgensen, H 2017, 'Antioxidant treatment attenuates lactate production in diabetic nephropathy', American Journal of Physiology: Renal Physiology, vol. 312, no. 1, pp. F192-F199. https://doi.org/10.1152/ajprenal.00148.2016
Hansen, ESS, Tougaard, RS, Nørlinger, TS, Mikkelsen, E, Nielsen, PM, Bertelsen, LB, Bøtker, HE, Jørgensen, HS & Laustsen, C 2017, 'Imaging porcine cardiac substrate selection modulations by glucose, insulin and potassium intervention: A hyperpolarized [1-(13) C]pyruvate study', NMR in Biomedicine, vol. 30, no. 6. https://doi.org/10.1002/nbm.3702
Iversen, AB, Busk, M, Bertelsen, LB, Laustsen, C, Munk, OL, Nielsen, T, Wittenborn, TR, Bussink, J, Lok, J, Stødkilde-Jørgensen, H & Horsman, MR 2017, 'The potential of hyperpolarized (13)C magnetic resonance spectroscopy to monitor the effect of combretastatin based vascular disrupting agents', Acta oncologica (Stockholm, Sweden), vol. 56, pp. 1-8. https://doi.org/10.1080/0284186X.2017.1351622
Kierulf-Lassen, C, Nielsen, PM, Qi, H, Damgaard, M, Laustsen, C, Pedersen, M, Krag, S, Birn, H, Nørregaard, R & Jespersen, B 2017, 'Unilateral nephrectomy diminishes ischemic acute kidney injury through enhanced perfusion and reduced pro-inflammatory and pro-fibrotic responses', P L o S One, vol. 12, no. 12, pp. e0190009. https://doi.org/10.1371/journal.pone.0190009
Laustsen, C 2016, 'Hyperpolarized 13C Magnetic Resonance Treatment Response Monitoring: A New Paradigm for Multiorgan Metabolic Assessment of Pharmacological Interventions?', Diabetes, vol. 65, no. 12, pp. 3529-3531. https://doi.org/10.2337/dbi16-0055
Nielsen, PM, Szocska Hansen, ES, Nørlinger, TS, Nørregaard, R, Bonde Bertelsen, L, Stødkilde Jørgensen, H & Laustsen, C 2016, 'Renal ischemia and reperfusion assessment with three-dimensional hyperpolarized (13) C,(15) N2-urea', Magnetic Resonance in Medicine, vol. 76, no. 5, pp. 1524-1530. https://doi.org/10.1002/mrm.26377
Nielsen, N, Laustsen, C & Bertelsen, LB 2016, '(13)C dynamic nuclear polarization for measuring metabolic flux in endothelial progenitor cells', Experimental Cell Research. https://doi.org/10.1016/j.yexcr.2016.10.002
Hansen, ESS, Stewart, NJ, Wild, JM, Stødkilde-Jørgensen, H & Laustsen, C 2016, 'Hyperpolarized (13) C,(15) N2 -Urea MRI for assessment of the urea gradient in the porcine kidney', Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26483
Nielsen, PM, Laustsen, C, Bertelsen, LB, Qi, H, Mikkelsen, E, Kristensen, MLV, Nørregaard, R & Stødkilde-Jørgensen, H 2016, 'In situ lactate dehydrogenase activity - a novel renal cortical imaging biomarker of tubular injury?', American Journal of Physiology: Renal Physiology, pp. ajprenal.00561.2015. https://doi.org/10.1152/ajprenal.00561.2015
Koellisch, U, Laustsen, C, Nørlinger, TS, Østergaard, JA, Flyvbjerg, A, Gringeri, CV, Menzel, MI, Schulte, RF, Haase, A & Stødkilde-Jørgensen, H 2016, 'Current state-of-the-art hyperpolarized 13C-acetate-to-acetylcarnitine imaging is not indicative of the altered balance between glucose and fatty acid utilization associated with diabetes', Physiological Reports, vol. 4, no. 17. https://doi.org/10.14814/phy2.12975
Juul, T, Palm, F, Nielsen, PM, Bertelsen, LB & Laustsen, C 2016, 'Ex vivo hyperpolarized MR spectroscopy on isolated renal tubular cells: A novel technique for cell energy phenotyping', Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26379
Hansen, ESS, Kim, S, Miller, JJ, Geferath, M, Morrell, G & Laustsen, C 2016, 'Fast Padé Transform Accelerated CSI for Hyperpolarized MRS', Tomography - A Journal for Imaging Research, vol. 2, no. 2, pp. 117-124. https://doi.org/10.18383/j.tom.2016.00154
Bertelsen, LB, Nielsen, PM, Qi, H, Nørlinger, TS, Zhang, X, Stødkilde-Jørgensen, H & Laustsen, C 2016, 'Diabetes induced renal urea transport alterations assessed with 3D hyperpolarized (13) C,(15) N-Urea', Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26256
Qi, H, Nørlinger, TS, Nielsen, PM, Bertelsen, LB, Mikkelsen, E, Xu, Y, Stødkilde Jørgensen, H & Laustsen, C 2016, 'Early diabetic kidney maintains the corticomedullary urea and sodium gradient', Physiological Reports, vol. 4, no. 5. https://doi.org/10.14814/phy2.12714
Bertelsen, LB, Nielsen, PM, Qi, H, Nørlinger, T, Zhang, X, Stødkilde-Jørgensen, H & Laustsen, C 2016, 'Diabetes induced renal urea transport alterations assessed with 3D hyperpolarized 13C,15N-urea', Magnetic Resonance in Medicine.
Agger, P, Lakshminrusimha, S, Laustsen, C, Gugino, S, Frandsen, J, Smerup, MH, Anderson, RH, Hjortdal, V & Steinhorn, RH 2015, 'The Myocardial Architecture changes in Persistent Pulmonary Hypertension of the Newborn in an Ovine Animal Model', Pediatric Research. https://doi.org/10.1038/pr.2015.263
Laustsen, C, Nørlinger, T, Christoffer Hansen, D, Qi, H, Mose Nielsen, P, Bonde Bertelsen, L, Henrik Ardenkjaer-Larsen, J & Stødkilde Jørgensen, H 2015, 'Hyperpolarized (13) C urea relaxation mechanism reveals renal changes in diabetic nephropathy', Magnetic Resonance in Medicine, vol. 75, no. 2, pp. 515-518. https://doi.org/10.1002/mrm.26036
Iversen, AB, Ringgaard, S, Laustsen, C, Stødkilde-Jørgensen, H, Bentzen, L, Busk, M & Horsman, MR 2015, 'Hyperpolarized magnetic resonance spectroscopy for assessing tumor hypoxia', Acta Oncologica, pp. 1393-1398. https://doi.org/10.3109/0284186X.2015.1070964
Laustsen, C, Søvsø Szocska Hansen, E, Pedersen, U, Bertelsen, LB, Ringgaard, S & Stødkilde-Jørgensen, H 2015, 'Acute porcine renal metabolic effect of endogastric soft drink administration assessed with hyperpolarized [1-13c]pyruvate', Magnetic Resonance in Medicine, vol. 74/2, pp. 558-563. https://doi.org/10.1002/mrm.25692
Koellisch, U, Laustsen, C, Nørlinger, TS, Østergaard, JA, Flyvbjerg, A, Gringeri, CV, Menzel, MI, Schulte, RF, Haase, A & Stødkilde-Jørgensen, H 2015, 'Investigation of metabolic changes in STZ-induced diabetic rats with hyperpolarized [1-13C]acetate', Physiological Reports, vol. 3, no. 8. https://doi.org/10.14814/phy2.12474
Lauritsen, SH, Bertelsen, LB, Daugård, P, Laustsen, C, Nielsen, N, Nygaard, JV & Stødkilde-Jørgensen, H 2015, 'Bioreactor for quantification of cell metabolism by MR-hyperpolarization', Biomedical Physics & Engineering Express, vol. 1, no. 4. https://doi.org/10.1088/2057-1976/1/4/047003
Qi, H, Zhang, X, Xu, Y, Wen, J, Xu, Y, Cheng, J, Chen, AP, Bertelsen, LB, Ringgaard, S, Laustsen, C & Stødkilde-Jørgensen, H 2015, 'Principle and application of hyperpolarized magnetic resonance spectroscopy', Chinese Journal of Magnetic Resonance Imaging , pp. 881-887.
Laustsen, C, Lipsø, K, Ostergaard, JA, Nørregaard, R, Flyvbjerg, A, Pedersen, M, Palm, F & Ardenkjær-Larsen, J-H 2014, 'Insufficient insulin administration to diabetic rats increases substrate utilization and maintains lactate production in the kidney', Physiological Reports, vol. 2, no. 12, 2, pp. 1-8. https://doi.org/10.14814/phy2.12233
Laustsen, C, Greferath, M, Ringgaard, S, Nielsen, NC & Ardenkjaer-Larsen, JH 2014, 'A new RF tagging pulse based on the Frank poly-phase perfect sequence', Journal of Magnetic Resonance, vol. 247, pp. 50-53. https://doi.org/10.1016/j.jmr.2014.08.011
Laustsen, C, Ardenkjaer-Larsen, JH, Pedersen, M, Ringgaard, S & Stødkilde-Jørgensen, H 2014, 'Hyperpolariseret magnetisk resonans kan in vivo kvantificere cellulær metabolisme', Ugeskrift for Laeger, vol. 176, no. 32, 176/32, pp. 1486-1489. <http://ugeskriftet.dk/files/ugeskriftet.dk/artikel_11562.pdf>
Ardenkjaer-Larsen, JH, Laustsen, C, Bowen, S & Rizi, R 2014, 'Hyperpolarized H2 O MR angiography', Magnetic Resonance in Medicine, vol. 71, no. 1, pp. 50-56. https://doi.org/10.1002/mrm.25033
Schmidt, R, Laustsen, C, Dumez, J-N, Kettunen, MI, Serrao, EM, Marco-Rius, I, Brindle, KM, Ardenkjaer-Larsen, JH & Frydman, L 2014, 'In vivo single-shot (13)C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding', Journal of Magnetic Resonance, vol. 240C, pp. 8-15. https://doi.org/10.1016/j.jmr.2013.12.013
Laustsen, C, Lycke, S, Palm, F, Østergaard, JA, Bibby, BM, Nørregaard, R, Flyvbjerg, A, Pedersen, M & Ardenkjaer-Larsen, JH 2014, 'High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging', Kidney International, vol. 86, pp. 67-74. https://doi.org/10.1038/ki.2013.504
Laustsen, C, Bowen, S, Sloth Vinding, M, Nielsen, NC & Ardenkjær-Larsen, JH 2014, 'Storage of magnetization as singlet order by optimal control designed pulses', Magnetic Resonance in Medicine, vol. 71, no. 3, pp. 921–926. https://doi.org/10.1002/mrm.24733
Lauritzen, MH, Laustsen, C, Butt, SA, Magnusson, SP, Søgaard, LV-C, Ardenkjaer-Larsen, JH & Akeson, P 2013, 'Enhancing the [(13) C]bicarbonate signal in cardiac hyperpolarized [1-(13) C]pyruvate MRS studies by infusion of glucose, insulin and potassium', NMR in Biomedicine, pp. 1496-1500. https://doi.org/10.1002/nbm.2982
Pileio, G, Bowen, S, Laustsen, C, Tayler, MCD, Hill-Cousins, JT, Brown, LJ, Brown, RCD, Ardenkjær-Larsen, JH & Levitt, MH 2013, 'Recycling and Imaging of Nuclear Singlet Hyperpolarization', Journal of the American Chemical Society, pp. 5084–5088. https://doi.org/10.1021/ja312333v
Laustsen, C, Østergaard, J, Lauritzen, MH, Nørregaard, R, Bowen, S, Søgaard, LV-C, Flyvbjerg, A, Pedersen, M & Ardenkjaer-Larsen, JH 2013, 'Assessment of early diabetic renal changes with hyperpolarised [1-(13) C]pyruvate', Diabetes - Metabolism: Research and Reviews (Online), pp. 125-129. https://doi.org/10.1002/dmrr.2370
Iversen, NK, Frische, S, Thomsen, K, Laustsen, C, Pedersen, M, Hansen, PBL, Bie, P, Fresnais, J, Berret, J-F, Baatrup, E & Wang, T 2013, 'Superparamagnetic iron oxide polyacrylic acid coated γ-Fe2O3 nanoparticles do not affect kidney function but cause acute effect on the cardiovascular function in healthy mice', Toxicology and Applied Pharmacology, vol. 266, no. 2, pp. 276-88. https://doi.org/10.1016/j.taap.2012.10.014
Vinding, MS, Laustsen, C, Maximov, I, Søgaard, LV, Ardenkjær-Larsen, JH & Nielsen, NC 2013, 'Dynamic nuclear polarization and optimal control spatial-selective 13C MRI and MRS', Journal of Magnetic Resonance, vol. 227, pp. 57-61. https://doi.org/10.1016/j.jmr.2012.12.002
Laustsen, C, Pileio, G, Tayler, MCD, Brown, LJ, Brown, RCD, Levitt, MH & Ardenkjær-Larsen, JH 2012, 'Hyperpolarized Singlet NMR on a Small Animal Imaging System', Magnetic Resonance in Medicine, vol. 68, pp. 1262-1265. <http://onlinelibrary.wiley.com/doi/10.1002/mrm.24430/pdf>
Butt, SA, Søgaard, LV-C, Magnusson, SP, Lauritzen, MH, Laustsen, C, Akeson, P & Ardenkjær-Larsen, JH 2012, 'Imaging cerebral 2-ketoisocaproate metabolism with hyperpolarized (13)C Magnetic Resonance Spectroscopic Imaging', Journal of Cerebral Blood Flow and Metabolism, vol. 32. https://doi.org/10.1038/jcbfm.2012.34
Pedersen, M, Laustsen, C, Perot, V, Basseau, F, Moonen, C & Grenier, N 2010, 'Renal hemodynamics and oxygenation in transient renal artery occluded rats evaluated with iron-oxide particles and oxygenation-sensitive imaging', Zeitschrift fuer Medizinische Physik, vol. 20, no. 2, pp. 134-142. https://doi.org/10.1016/j.zemedi.2010.02.002
Rasmussen, AS, Lauridsen, H, Laustsen, C, Jensen, B, Fjord, S, Uhrenholt, L, Boel, LWT, Uldbjerg, N, Wang, T & Pedersen, M 2010, 'High-resolution ex vivo magnetic resonance angiography: a feasibility study on biological and medical tissues', B M C Physiology, vol. 10, no. 3. https://doi.org/10.1186/1472-6793-10-3
Laustsen, C, Ringgaard, S, Pedersen, M & Nielsen, NC 2010, 'Quadrupolar-coupling-specific binomial pulse sequences for in vivo(23)Na NMR and MRI', Journal of Magnetic Resonance, vol. 206, pp. 139-146. https://doi.org/10.1016/j.jmr.2010.06.017

Abstracts

NON-INVASIVE ASSESSMENT OF THE FIBROGENIC RESPONSE FOLLOWING ISCHEMIA/REPERFUSION INJURY IN RODENTS

Rasmussen, D., Nielsen, P. M., Mariager, C., Laustsen, C., Karsdal, M., Genovese, F., Molmer, M. & Norregaard, R., May 2018, p. 102-103. 2 p.

3D Reconstruction and Fiber Quantification in the Pig Lower Esophageal Sphincter region In vitro Diffusion Tensor Imaging

Liao, D., Gregersen, H., Agger, P., Laustsen, C., Ringgaard, S., Stødkilde-Jørgensen, H. & Zhao, J., Nov 2017, p. 57. 1 p.

REAL-TIME, IN VIVO MEASUREMENTS OF PYRUVATE METABOLISM IN THE LIVER AND KIDNEYS OF BRAIN-DEAD RATS WITH HYPERPOLARIZED [1-13C]-PYRUVATE MAGNETIC RESONANCE IMAGING

Van Erp, A., Qi, H., Ottens, P., Norregaard, R., Pedersen, M., Leuvenink, H., Laustsen, C. & Jespersen, B., Sep 2017, p. 573-573. 1 p.

Hyperpolarized [1-13C]-MRI in an ectothermic repile

Hansen, K., Nielsen, P. M., Søvsø Szocska Hansen, E., Williams, C., Joyce, W., Pedersen, M., Wang, T. & Laustsen, C., 27 Apr 2017.

Changes in overall ventricular myocardial architecture in the setting of a porcine animal model of right ventricular dilation

Agger, P., Ilkjær, C., Laustsen, C., Smerup, M. H., Frandsen, J., Ringgaard, S., Pedersen, M., Partridge, J. B., Anderson, R. H. & Hjortdal, V. E., 2017.

Dynamic remodelling of the right ventricular myocardium through the cardiac cycle

Christensen, C. O., Laustsen, C., Hjortdal, V. E. & Agger, P., 2017.

Myocardial metabolism in heart failure induced by right ventricular volume overload

Bøgh, N., Petersen, M. F., Christensen, C. O., Hjortdal, V. E., Søvsø Szocska Hansen, E., Laustsen, C. & Agger, P., 2017.

The architecture of the right ventricular myocardium changes through the cardiac cycle

Christensen, C. O., Laustsen, C., Hjortdal, V. E. & Agger, P., 2017.

In Situ lactate dehydrogenase activiy-a novel renal cortical imaging biomarker of tubular injury?

Nielsen, P. M., Laustsen, C., Bertelsen, L. B., Qi, H., Mikkelsen, E., Kristensen, M-L. V., Nørregaard, R. & Stødkilde-Jørgensen, H., 3 Apr 2016.

Oxygen metabolic competition in the lactic acidotic diabetic kidney: A point of no return?

Laustsen, C., Lipsø, H. K. W., Østergaard, J. A., Nielsen, P. M., Flyvbjerg, A., Pedersen, M., Palm, F. & Ardenkjær-Larsen, J. H., 3 Apr 2016.

Diffusion tensor magnetic resonance imaging for evaluation of changes of myocardial architecture through the cardiac cycle in the right ventricle

Christensen, C. O., Agger, P., Laustsen, C. & Hjortdal, V. E., 2016.

Renal Urea Transport Alterations with Prolonged Hyperglycaemia

Bertelsen, L. B., Nielsen, P. M., Qi, H., Nørlinger, T., Zhang, X., Stødkilde-Jørgensen, H. & Laustsen, C., 2016.

A Gadgetron based hyperpolarised 13C analysis module for multi-vendor clinical translation

Hansen, D. C., F. Schulte, R., Sangild, T., Ringgaard, S., Stødkilde-Jørgensen, H. & Laustsen, C., 2015.

Investigation of Metabolic Changes in STZ Induced Diabetic Rats with Hyperpolarized [1-13C]Acetate

Koellisch, U., Laustsen, C., Nørlinger, T., Østergaard, J. A., Flyvbjerg, A., V. Gringeri, C., I. Menzel, M., F. Schulte, R., Haase, A. & Stødkilde-Jørgensen, H., 2015, In: Proc ISMRM. 1890.

Sa1112 Three-Dimensional Myoarchitecture of Porcine Gastro-Esophageal Junction With Diffusion Tensor Imaging

Gregersen, H., Liao, D., Zhao, J., Ringgaard, S., Agger, P., Laustsen, C. & Stødkilde-Jørgensen, H., 2015, In: Gastroenterology. 148

The Myocardial Architecture Changes due to Persistent Pulmonary Hypertension of the Newborn in an Ovine Animal Model

Agger, P., Lakshminrusimha, S., Laustsen, C., Gugino, S., Frandsen, J., Smerup, M. H., Anderson, R. H., Hjortdal, V. E. & Steinhorn, R. H., 2015, In: Journal of Pediatric and Neonatal Individualized Medicine. 79, 4, p. 565-74 10 p.

Three-dimensional Myoarchitecture of Porcine Esophago-Gastric Junction with Diffusion Tensor Imaging. Selected for poster presentation.

Gregersen, H., Liao, D., Zhao, J., Ringgaard, S., Agger, P., Laustsen, C. & Stødkilde-Jørgensen, H., 2015.

Hyperpolarized 13C MRS reveals oxygen sensitive pseudo hypxia in the diabetic kidney

Laustsen, C., Lipsoe, K., Palm, F., Østergaard, J. A., Nørregaard, R., Flyvbjerg, A., Pedersen, M. & Ardenkjaer-Larsen, J. H., 21 Mar 2014.

Myocardial remodelling due to right ventricular dilatation in congenital heart disease

Agger, P., Ilkjær, C., Laustsen, C., Smerup, M. H., Nielsen-Kudsk, J. E., Pedersen, M. & Hjortdal, V. E., 2014.

A Ultra Fast 79Br B1 Calibration Method for 13C Coils for Hyperpolarized Studies

Laustsen, C. & Ardenkjær-Larsen, J. H., 6 Oct 2011, In: ESMRMB.

Longtime storage of hyperpolarization via singlet states in high field

Pileio, G., Laustsen, C., Brown, L. J., Bocan, J., Tayler, M. C. D., Brown, R. C. D., Ardenkjaer-Larsen, J. H. & Levitt, M. H., 27 Jul 2011, In: EUROMAR.

Ex vivo ischemic kidney damage 23Na relaxometry

Laustsen, C., Ringgaard, S., Damkjær, M. & Pedersen, M., 7 May 2011, In: Proc ISMRM.

Hyperpolarized water for interventional angiography

Ardenkjær-Larsen, J. H., Laustsen, C., Pullinger, B., Kadlecek, S., Emami, K. & Rizi, R., 7 May 2011, In: Proc ISMRM.

Optimal control developed 23Na NMR pulses for selective detection of a specific broadband quadrupolar coupling range

Laustsen, C., 2010.

Development of a clinical 23Na quantification NMR/MRI technique

Laustsen, C., 2009.

MRI zoo

Laustsen, C., 2009.

Development of a clinical 23Na quantification NMR/MRI technique

Laustsen, C., 27 Sep 2008.

Lectures

13C & 23Na

Christoffer Laustsen (Lecturer)

12 Jul 2010

34th Danish NMR meeting

Christoffer Laustsen (Participant)

21 Jan 201322 Jan 2013

A small fumarate story

Christoffer Laustsen (Lecturer)

17 Dec 2019

Acquisition Strategies for Hyperpolarized Spin Systems

Christoffer Laustsen (Participant)

25 Aug 201327 Aug 2013

Assesment of diabetic nephropathy with Hyperpolarised [1-13C]Pyruvat

Christoffer Laustsen (Lecturer)

20 Jan 2012

Assessment of early diabetic renal changes with hyperpolarised [1-13C]pyruvate

Christoffer Laustsen (Lecturer)

22 Nov 2012

Binomial sequences for S=3/2 nuclei for selective detection of intracellular sodium

Christoffer Laustsen (Lecturer)

25 Jan 2010

COST PARENCHIMA WP1 leader update

Christoffer Laustsen (Lecturer)

4 Oct 2018

COST Spin Hyperpolarisation meeting

Christoffer Laustsen (Participant)

29 Jun 20121 Jul 2012

COST summer school 2012 on Spin-Hyperpolarization

Christoffer Laustsen (Participant)

29 Oct 20122 Nov 2012

Cardiac metabolism assessed with Hyperpolarized MR

Christoffer Laustsen (Lecturer)

27 Nov 2012

Comparison of perfusion markers in the ex-vivo perfused porcine kidney: hyperpolarized [1-13C]pyruvate versus gold standard 1H DCE MRI

Christian Østergaard Mariager (Invited speaker), Esben Søvsø Szocska Hansen (Other), Sabrina Kahina Bech (Other), Anders Munk (Other), Mads Dam Lyhne (Other), Karsten Søberg (Other), Peter Fast Nielsen (Other), Steffen Ringgaard (Other) & Christoffer Laustsen (Other)

2019

EPIC programming

Christoffer Laustsen (Participant)

16 Sep 201319 Sep 2013

European Network for Hyperpolarization Physics and Methodology in NMR and MRI (External organisation)

Christoffer Laustsen (Member)

2012 → …

European Network for Hyperpolarization Physics and Methodology in NMR and MRI (External organisation)

Christoffer Laustsen (Member)

2012 → …

Fast Pade Transform accelerated CSI for hyperpolarized MRS

Christoffer Laustsen (Lecturer)

27 Jun 2014

Fifth International Workshop on Metabolic Imaging

Christoffer Laustsen (Participant)

18 Oct 201820 Oct 2018

Fractional perfusion: A simple semi-parametric measure for clinical translation of hyperpolarized 13C MR?

Christoffer Laustsen (Lecturer), Per Mose Nielsen (Lecturer) & Steffen Ringgaard (Lecturer)

20 Oct 2017

Frank NMR and MRI

Christoffer Laustsen (Lecturer)

5 Feb 201112 Feb 2011

Hyperpolariseret 13C metabolisk MR er en ny og meget spændende teknologi, der viser unikke egenskaber til in vivo undersøgelser non invasivt. Jeg vil i dette foredrag vise mine indledende resultater og introducerer til den grundlæggende beskrivelse af DNP teknikken.

Christoffer Laustsen (Lecturer)

26 May 2010

Hyperpolariseret MR til human anvendelse

Christoffer Laustsen (Lecturer)

1 Jun 2017

Hyperpolarization - Clinical Potential & Relevance

Christoffer Laustsen (Lecturer)

26 Apr 2017

Hyperpolarized 13C MRS reveals hypoxia accelerates pseudo hypoxia in the diabetic kidney

Christoffer Laustsen (Lecturer)

28 Apr 2014

Hyperpolarized 13C development for diabetes

Christoffer Laustsen (Lecturer)

13 Nov 2013

Hyperpolarized Functional and Metabolic Kidney Imaging

Christoffer Laustsen (Lecturer)

20 Oct 2018

Hyperpolarized Media MR committee member (External organisation)

Christoffer Laustsen (Secretary)

20162019

Hyperpolarized Metabolic and Functional Cardio and Renal MR Imaging

Christoffer Laustsen (Lecturer)

2 Feb 2017

Hyperpolarized [1-13C]Pyruvate CMR and the potential of DMI at 3T

Christoffer Laustsen (Lecturer)

6 Mar 2020

Hyperpolarized long-lived storage: A potential solution to MRI guided therapeutics and monitoring

Christoffer Laustsen (Lecturer)

16 Oct 2012

Hyperpolarized magnetic resonance Imaging – potential and pitfalls

Christoffer Laustsen (Lecturer)

18 Sep 2019

Hyperpolarized magnetic resonance Imaging – potential for placenta imaging ?

Christoffer Laustsen (Lecturer)

19 Sep 2019

Hyperpolarized singlet state storage: Extending the life-time of DNP

Christoffer Laustsen (Lecturer)

22 Jan 2013

Hyperpolarized 13C metabolic imaging – increasing MRI more than 20.000 times

Christoffer Laustsen (Lecturer)

23 Oct 2019

Imaging oxygen metabolism: new findings in both animal and human studies

Christoffer Laustsen (Lecturer)

24 May 2016

Imaging renal functional and metabolic alterations with hyperpolarized MR

Christoffer Laustsen (Lecturer)

9 Oct 2017

In vivo and ex vivo [1-13C]pyruvate examinations

Christoffer Laustsen (Lecturer)

14 Mar 201915 Mar 2019

Induction heating of gold particles in an MRI-system

Christoffer Laustsen (Lecturer)

20 Jun 2007

International Society for Magnetic Resonance in Medicine (External organisation)

Christoffer Laustsen (Member)

2010 → …

International Society for Magnetic Resonance in Medicine Nordic Chapter (External organisation)

Christoffer Laustsen (Member)

2012 → …

Introduction to Hyperpolarised MR & Metabolism

Christoffer Laustsen (Lecturer)

11 May 2016

LEADER COURSE

Christoffer Laustsen (Participant)

6 Aug 201217 Aug 2012

Leading the Virtual Company – PasteurProgram 2015

Christoffer Laustsen (Participant)

2015 → …

METABOLIC IMAGING WITH HYPERPOLARIZED MR – POTENTIAL FOR DRUG DEVELOPMENT

Christoffer Laustsen (Lecturer)

14 Mar 2018

MR assessment of tumor metabolism and perfusion

Christoffer Laustsen (Lecturer)

2 Dec 2019

Measurements of metabolism using hyperpolarized MRI

Christoffer Laustsen (Lecturer)

6 Mar 2013

Metabolic imaging with hyperpolarized MR

Christoffer Laustsen (Lecturer)

18 Jan 2018

Molecular imaging: Hyperpolarisation, magnetization transfer, CEST

Christoffer Laustsen (Lecturer)

11 Oct 2017

New non-invasive imaging techniques for animal use

Christoffer Laustsen (Lecturer)

21 Sep 2012

Opfindelse og anvendelse af Hyperpolarisatoren

Christoffer Laustsen (Lecturer)

13 Sep 2014

Optimal Control Singlet State Storage of hyperpolarized compounds

Christoffer Laustsen (Lecturer)

25 Jul 2012

Oxygen metabolic competition in the diabetic kidney: A new metabolic phenotype in animal models of diabetes?

Christoffer Laustsen (Lecturer)

19 Aug 2017

PhD Examination – Charlotte Daniels

Christoffer Laustsen (Participant)

9 Nov 2017

Pre-clinical DNP

Christoffer Laustsen (Lecturer)

5 Oct 20117 Oct 2011

Pre-clinical SPINLAB’ing

Christoffer Laustsen (Lecturer)

26 Apr 2017

Pre-clinical considerations - for clinical translation

Christoffer Laustsen (Lecturer)

16 Mar 2018

Preclinical Hyperpolarizared MRI

Christoffer Laustsen (Lecturer)

4 Dec 2017

Pushing the frontiers in hyperpolarized MR-spectroscopic imaging: ready for clinical use

Christoffer Laustsen (Lecturer)

22 Oct 2019

RENAL METABOLISM DURING ALTERED OXYGEN AVAILABILITY, ASSESSED WITH HYPERPOLARIZED [1-13C]PYRUVATE

Christoffer Laustsen (Lecturer)

28 Aug 2013

Renal functional and metabolic imaging using hyperpolarized MR 

Christoffer Laustsen (Lecturer)

3 Dec 2017

ScanBalt Forum 2014

Christoffer Laustsen (Speaker)

9 Oct 2014

Sensitivity Challenges in Contemporary Biomolecular Magnetic Resonance

Christoffer Laustsen (Participant)

27 Feb 201328 Feb 2013

Swine renal and hepatic metabolism assessed with hyperpolarized MR

Christoffer Laustsen (Lecturer)

9 Feb 201510 Feb 2015

The Aarhus vision for Hyperpolarized 13C MRI

Christoffer Laustsen (Lecturer)

13 Aug 2019

University of Copenhagen (External organisation)

Christoffer Laustsen (Member)

13 Aug 2019

Using Hyperpolarized 13C Labeled Urea as a Possible Endogenous Marker for Identifying Renal Impairment

Christoffer Laustsen (Lecturer)

26 Feb 2016

Education

2011Laboratory Animal science certified
2009Aarhus University — Mcs Nanoscience
2007Aarhus University — Bcs Nanoscience