Christina C. Dahm

Meat and haem iron intake in relation to glioma in the European Prospective Investigation into Cancer and Nutrition study

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Heather A Ward, United Kingdom
  • Alicia Gayle, United Kingdom
  • Paula Jakszyn, Spain
  • Melissa Merritt, United Kingdom
  • Beatrice Melin, Sweden
  • Heinz Freisling, France
  • Elisabete Weiderpass, Sweden
  • Anne Tjonneland, Denmark
  • Anja Olsen
  • Christina C Dahm
  • Kim Overvad
  • Verena Katzke, Germany
  • Tilman Kühn, Germany
  • Heiner Boeing, Germany
  • Antonia Trichopoulou, Greece
  • Pagona Lagiou, Greece
  • Andreas Kyrozis, Greece
  • Domenico Palli, Italy
  • Vittorio Krogh, Italy
  • Rosario Tumino, Italy
  • Fulvio Ricceri, Italy
  • Amalia Mattiello, Italy
  • Bas Bueno-de-Mesquita, Netherlands
  • Petra H Peeters, Netherlands
  • José Ramón Quirós, Spain
  • Antonio Agudo, Spain
  • Miguel Rodriguez-Barranco, Grenada
  • Nerea Larrañaga, Spain
  • José M Huerta, Spain
  • Aurelio Barricarte, Spain
  • Emily Sonestedt, Sweden
  • Isabel Drake, Sweden
  • Maria Sandström, Sweden
  • Ruth C Travis, United Kingdom
  • Pietro Ferrari, France
  • Elio Riboli, United Kingdom
  • Amanda J Cross, United Kingdom

Diets high in red or processed meat have been associated positively with some cancers, and several possible underlying mechanisms have been proposed, including iron-related pathways. However, the role of meat intake in adult glioma risk has yielded conflicting findings because of small sample sizes and heterogeneous tumour classifications. The aim of this study was to examine red meat, processed meat and iron intake in relation to glioma risk in the European Prospective Investigation into Cancer and Nutrition study. In this prospective cohort study, 408 751 individuals from nine European countries completed demographic and dietary questionnaires at recruitment. Multivariable Cox proportional hazards models were used to examine intake of red meat, processed meat, total dietary iron and haem iron in relation to incident glioma. During an average follow-up of 14.1 years, 688 incident glioma cases were diagnosed. There was no evidence that any of the meat variables (red, processed meat or subtypes of meat) or iron (total or haem) were associated with glioma; results were unchanged when the first 2 years of follow-up were excluded. This study suggests that there is no association between meat or iron intake and adult glioma. This is the largest prospective analysis of meat and iron in relation to glioma and as such provides a substantial contribution to a limited and inconsistent literature.

Original languageEnglish
JournalEuropean Journal of Cancer Prevention
Volume27
Issue4
Pages (from-to)379-383
Number of pages5
ISSN0959-8278
DOIs
Publication statusPublished - Jul 2018

    Research areas

  • brain cancer, dietary iron, European Prospective Investigation into Cancer and Nutrition, glioma, haem iron, N-nitroso compounds, processed meat, red meat, N -nitroso compounds, METAANALYSIS, RED MEAT, RISK, ADULT GLIOMA, DIETARY, CONSUMPTION

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