Christina C. Dahm

Main nutrient patterns are associated with prospective weight change in adults from 10 European countries

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Heinz Freisling, International Agency for Research on Cancer (IARC-WHO), 150, Cours Albert Thomas, 69372, Lyon Cedex 08, France. freislingh@fellows.iarc.fr.
  • ,
  • Pedro T Pisa, International Agency for Research on Cancer (IARC-WHO), 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.
  • ,
  • Pietro Ferrari, International Agency for Research on Cancer (IARC-WHO), 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.
  • ,
  • Graham Byrnes, International Agency for Research on Cancer (IARC-WHO), 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.
  • ,
  • Aurelie Moskal, International Agency for Research on Cancer (IARC-WHO), 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.
  • ,
  • Christina C Dahm
  • Anne-Claire Vergnaud, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
  • ,
  • Marie-Christine Boutron-Ruault, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.
  • ,
  • Guy Fagherazzi, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.
  • ,
  • Claire Cadeau, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.
  • ,
  • Tilman Kühn, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • ,
  • Jasmine Neamat-Allah, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • ,
  • Brian Buijsse, Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany
  • ,
  • Heiner Boeing, Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany
  • ,
  • Jytte Halkjær, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.
  • ,
  • Anne Tjonneland, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.
  • ,
  • Camilla P Hansen
  • ,
  • J Ramón Quirós, Public Health Directorate, Asturias, Spain.
  • ,
  • Noémie Travier, Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain.
  • ,
  • Esther Molina-Montes, Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs, Hospitales Universitarios de Granada, Universidad de Granada, Granada, Spain.
  • ,
  • Pilar Amiano, Public Helath Division of Gipuzkoa, Basque Health Department, BioDonostia Research Institute, San Sebastián, Spain.
  • ,
  • José M Huerta, CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
  • ,
  • Aurelio Barricarte, Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain; Public Health Division of Gipuzkoa, BIODonostia Research Institute, San Sebastian, Spain.
  • ,
  • Kay-Tee Khaw, University of Cambridge
  • ,
  • Nicholas Wareham, Medical Research Council Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • ,
  • Tim J Key, Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • ,
  • Dora Romaguera, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
  • ,
  • Yunxia Lu, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
  • ,
  • Camille M Lassale, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
  • ,
  • Androniki Naska, Hellenic Health Foundation, Athens, Greece.
  • ,
  • Philippos Orfanos, Hellenic Health Foundation, Athens, Greece.
  • ,
  • Antonia Trichopoulou, Hellenic Health Foundation, Athens, Greece.
  • ,
  • Giovanna Masala, Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.
  • ,
  • Valeria Pala, Epidemiology and Prevention Unit, Department of Preventive & Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • ,
  • Franco Berrino, Epidemiology and Prevention Unit, Department of Preventive & Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • ,
  • Rosario Tumino, Cancer Registry, Azienda Ospedaliera "Civile M.P. Arezzo", Ragusa, Italy.
  • ,
  • Fulvio Ricceri, Unit of Cancer Epidemiology - CERMS, Department of Medical Sciences, University of Turin and Città della Salute e della Scienza Hospital, Turin, Italy.
  • ,
  • Maria Santucci de Magistris, Department of Clinical and Experimental Medicine, Frederico II University, Naples, Italy.
  • ,
  • H Bas Bueno-de-Mesquita, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
  • ,
  • Marga C Ocké, The National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
  • ,
  • Emily Sonestedt, Lund University
  • ,
  • Ulrika Ericson, Lund University
  • ,
  • Mattias Johansson, International Agency for Research on Cancer (IARC-WHO), 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.
  • ,
  • Guri Skeie, Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway.
  • ,
  • Elisabete Weiderpass, Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway.
  • ,
  • Tonje Braaten, Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway.
  • ,
  • Petra H M Peeters, Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  • ,
  • Nadia Slimani, International Agency for Research on Cancer (IARC-WHO), 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.

PURPOSE: Various food patterns have been associated with weight change in adults, but it is unknown which combinations of nutrients may account for such observations. We investigated associations between main nutrient patterns and prospective weight change in adults.

METHODS: This study includes 235,880 participants, 25-70 years old, recruited between 1992 and 2000 in 10 European countries. Intakes of 23 nutrients were estimated from country-specific validated dietary questionnaires using the harmonized EPIC Nutrient DataBase. Four nutrient patterns, explaining 67 % of the total variance of nutrient intakes, were previously identified from principal component analysis. Body weight was measured at recruitment and self-reported 5 years later. The relationship between nutrient patterns and annual weight change was examined separately for men and women using linear mixed models with random effect according to center controlling for confounders.

RESULTS: Mean weight gain was 460 g/year (SD 950) and 420 g/year (SD 940) for men and women, respectively. The annual differences in weight gain per one SD increase in the pattern scores were as follows: principal component (PC) 1, characterized by nutrients from plant food sources, was inversely associated with weight gain in men (-22 g/year; 95 % CI -33 to -10) and women (-18 g/year; 95 % CI -26 to -11). In contrast, PC4, characterized by protein, vitamin B2, phosphorus, and calcium, was associated with a weight gain of +41 g/year (95 % CI +2 to +80) and +88 g/year (95 % CI +36 to +140) in men and women, respectively. Associations with PC2, a pattern driven by many micro-nutrients, and with PC3, a pattern driven by vitamin D, were less consistent and/or non-significant.

CONCLUSIONS: We identified two main nutrient patterns that are associated with moderate but significant long-term differences in weight gain in adults.

Original languageEnglish
JournalEuropean Journal of Nutrition
Volume55
Issue6
Pages (from-to)2093-2104
Number of pages12
ISSN1436-6207
DOIs
Publication statusPublished - Sep 2016

    Research areas

  • Journal Article

See relations at Aarhus University Citationformats

ID: 104271847