Aarhus University Seal / Aarhus Universitets segl

Christian Würtz Heegaard

  1. 2020
  2. E-pub ahead of print

    Gene therapy to the blood-brain barrier with resulting protein secretion as a strategy for treatment of Niemann Picks type C2 disease. / Hede, Eva ; Christiansen, Christine Bodelund; Würtz Heegaard, Christian; Moos, Torben; Burkhart, Annette.

    In: Journal of Neurochemistry, 19.02.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Binding and intracellular transport of 25-hydroxycholesterol by Niemann-Pick C2 protein. / Petersen, Daniel; Reinholdt, Peter; Szomek, Maria; Hansen, Selina Kruuse; Poongavanam, Vasanthanathan; Dupont, Alice; Heegaard, Christian W.; Krishnan, Kathiresan; Fujiwara, Hideji; Covey, Douglas F.; Ory, Daniel S.; Kongsted, Jacob; Wüstner, Daniel.

    In: Biochimica et Biophysica Acta - Biomembranes, 01.02.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2019
  5. Published

    Cyano-B12 or Whey Powder with Endogenous Hydroxo-B12 for Supplementation in B12 Deficient Lactovegetarians. / Naik, Sadanand; Mahalle, Namita ; Greibe, Eva ; Ostenfeld, Marie; Heegaard, Christian Würtz; Nexø, Ebba; Fedosov, Sergey.

    In: Nutrients, Vol. 11, No. 10, 2382, 06.10.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Vitamin B 12 and its binding proteins in milk from cow and buffalo in relation to bioavailability of B 12. / Fedosov, Sergey N.; Nexo, Ebba; Heegaard, Christian W.

    In: Journal of Dairy Science, Vol. 102, No. 6, 06.2019, p. 4891-4905.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Kinetic analysis of transcellular passage of the cobalamin-transcobalamin complex in Caco-2 monolayers. / Juul, Christian Bredgaard; Fedosov, Sergey; Nexø, Ebba; Heegaard, Christian Würtz.

    In: Molecular Biology of the Cell, Vol. 30, No. 4, 15.02.2019, p. 467-477.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Comparative Bioavailability of Synthetic B12 and Dietary Vitamin B12 Present in Cow and Buffalo Milk. / Mahalle, Namita ; Bhide, Vijayshri; Greibe, Eva; Heegaard, Christian Würtz; Nexø, Ebba; Fedosov, Sergey; Naik, Sadanand.

    In: Nutrients, Vol. 11, No. 2, 304, 01.02.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. 2018
  10. Published

    Increase in circulating holotranscobalamin after oral administration of cyanocobalamin or hydroxocobalamin in healthy adults with low and normal cobalamin status. / Greibe, Eva; Mahalle, Namita ; Bhide, Vijayshri; Heegaard, Christian Würtz; Naik, Sadanand; Nexø, Ebba.

    In: European Journal of Nutrition, Vol. 57, No. 8, 8, 12.2018, p. 2847-2855.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Analysis of cholesterol export from endo-lysosomes by Niemann Pick C2 protein using combined fluorescence and X-ray microscopy. / Dupont, Alice; Lund, Frederik W; Jensen, Marie Louise V ; Szomek, Maria; K Nielsen, Gitte ; Heegaard, Christian Würtz; Guttmann, Peter ; Werner, Stephan ; McNally, James ; Schneider, Gerd ; Kapishnikov, Sergey; Wüstner, Daniel.

    In: bioRxiv, 06.11.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  12. Published

    Differences in tissue distribution of cyano-B12 and hydroxo-B12 one week after oral intake: An experimental study in male Wistar rats. / Greibe, Eva; Nymark, Ole; Fedosov, Sergey; Heegaard, Christian Würtz; Nexø, Ebba.

    In: Nutrients, Vol. 10, No. 10, 12.10.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Dietary Intake of Vitamin B12 is Better for Restoring a Low B12 Status Than a Daily High-Dose Vitamin Pill: An Experimental Study in Rats. / Greibe, Eva; Nymark, Ole; Fedosov, Sergey; Heegaard, Christian Würtz; Nexø, Ebba.

    In: Nutrients, Vol. 10, No. 8, 15.08.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    The tissue profile of metabolically active coenzyme forms of vitamin B12 differs in vitamin B12-depleted rats treated with hydroxo-B12 or cyano-B12. / Greibe, Eva; Kornerup, Linda Skibsted; Juul, Christian Bredgaard; Fedosov, Sergey; Heegaard, Christian Würtz; Nexø, Ebba.

    In: British Journal of Nutrition, Vol. 120, 14.07.2018, p. 49-56.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts. / Berzina, Zane; Solanko, Lukasz M.; Mehadi, Ahmed S.; Jensen, Maria Louise V.; Lund, Frederik W.; Modzel, Maciej; Szomek, Maria; Solanko, Katarzyna A.; Dupont, Alice; Nielsen, Gitte Krogh; Heegaard, Christian W.; Ejsing, Christer S.; Wüstner, Daniel.

    In: Chemistry and Physics of Lipids, Vol. 213, 01.07.2018, p. 48-61.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats. / Kornerup, Linda Skibsted; Fedosov, Sergey; Juul, Christian Bredgaard; Greibe, Eva; Heegaard, Christian Würtz; Nexø, Ebba.

    In: European Journal of Nutrition, Vol. 57, No. 4, 4, 06.2018, p. 1459-1469.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    Binding of aquocobalamin to bovine casein and its peptides via coordination to histidine residues. / Fedosov, Sergey; Nexø, Ebba; Heegaard, Christian Würtz.

    In: International Dairy Journal, Vol. 76, 01.2018, p. 30-39.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Niemann-Pick type C2 protein supplementation in experimental non-alcoholic fatty liver disease. / Christensen, Claus Uhrenholt; Glavind, Emilie; Thomsen, Karen Louise; Kim, Yong Ook; Heebøll, Sara; Schuppan, Detlef; Hamilton-Dutoit, Stephen; Würtz Heegaard, Christian; Grønbæk, Henning.

    In: P L o S One, Vol. 13, No. 3, 2018, p. e0192728.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. 2017
  20. Published

    Effect of 8-week oral supplementation with 3-µg cyano-B12 or hydroxo-B12 in a vitamin B12-deficient population. / Greibe, Eva; Mahalle, Namita ; Bhide, Vijayshri; Fedosov, Sergey; Heegaard, Christian Würtz; Naik, Sadanand; Nexø, Ebba.

    In: European Journal of Nutrition, Vol. 58, No. 1, 05.12.2017, p. 261-270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    Absorption of vitamin B12 administered in Buffalo milk: An experimental study in rats. / Greibe, Eva; Nymark, Ole; Fedosov, Sergey; Ostenfeld, Marie; Heegaard, Christian Würtz; Nexø, Ebba.

    In: SciTz Nutrition and Food Science, Vol. 2(1):1006, 11.11.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. 2016
  23. Published

    Absorption and retention of free and milk protein-bound cyano- and hydroxocobalamins : An experimental study in rats. / Kornerup, Linda Skibsted; Juul, Christian Bredgaard; Fedosov, Sergey; Heegaard, Christian Würtz; Greibe, Eva; Nexø, Ebba.

    In: Biochimie, Vol. 126, 07.2016, p. 57-62.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. 2015
  25. Published

    Dose-Response Effect of Whey Protein Consumed as Premeal on Postprandial Lipemia in Subjects with the Metabolic Syndrome. / Bjørnshave, Ann; Heegaard, Christian Würtz; Hermansen, Kjeld.

    In: Diabetes, Vol. 64 , No. Supplement: 1, 2482-PO, 05.06.2015, p. A268.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference articleResearchpeer-review

  26. 2014
  27. Published

    SpatTrack : An Imaging Toolbox for Analysis of Vesicle Motility and Distribution in Living Cells. / Lund, Frederik W; Jensen, Maria Louise V; Christensen, Tanja; Nielsen, Gitte Krogh; Heegaard, Christian W; Wüstner, Daniel.

    In: Traffic, Vol. 15, No. 12, 22.09.2014, p. 1406-1429.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    Effects of Niemann-Pick Type C2 protein treatment on non-alcoholic steatohepatitis in a rat model. / Christensen, Claus Uhrenholt; Glavind, Emilie; Thomsen, Karen Louise; Heegaard, Christian Würtz; Grønbæk, Henning.

    2014. Abstract from Danish Society for Gastroenterology and Hepatology, 3. årsmøde, 5.-6. september 2014, Hindsgavl Allé, 5500 Middelfart, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  29. Published

    Imaging the myocardium at risk with (99m)Tc-lactadherin administered after reperfusion in a porcine model. / Poulsen, Runa Hyldgaard; Rasmussen, Jan Trige; Bøtker, Hans Erik; Wæhrens, Lasse Neumann; Falborg, Lise; Heegaard, Christian Würtz; Rehling, Michael.

    In: Nuclear Medicine and Biology, Vol. 41, No. 1, 01.2014, p. 114-119.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2013
  31. Published

    Cell injury after ischemia and reperfusion in the porcine kidney evaluated by radiolabelled microspheres, sestamibi, and lactadherin. / Pedersen, Stine S; Keller, Anna K; Nielsen, Marie K.; Jespersen, Bente; Falborg, Lise; Rasmussen, Jan T; Heegaard, Christian Würtz; Rehling, Michael.

    In: EJNMMI research, Vol. 3, No. 62, 07.08.2013, p. 1-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    Pharmacokinetics of the phosphatidylserine tracers 99mTc-lactadherin and 99mTc-annexin V in pigs. / Poulsen, Runa H; Rasmussen, Jan T; Ejlersen, June Anita; Flø, Christian; Falborg, Lise; Heegaard, Christian Würtz; Rehling, Michael.

    In: EJNMMI research, Vol. 3, No. 15, 09.03.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. 2011
  34. Published

    Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease. / Nielsen, Gitte Krogh; Dagnaes-Hansen, Frederik; Holm, Ida Elisabeth; Meaney, Steve; Symula, Derek; Andersen, Niels Trolle; Heegaard, Christian Würtz.

    In: P L o S One, Vol. 6, No. 11, 03.11.2011, p. e27287.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    The toxicity of bovine α-lactalbumin made lethal to tumor cells is highly dependent on oleic acid and induces killing in cancer cell lines and noncancer-derived primary cells. / Brinkmann, Christel Rothe; Heegaard, Christian Würtz; Petersen, Torben Ellebæk; Jensenius, Jens Christian; Thiel, Steffen.

    In: F E B S Journal, Vol. 278, No. 11, 01.06.2011, p. 1955-67.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human (alpha)-lactalbumin. / Brinkmann, C R; Thiel, S; Larsen, M K; Petersen, T E; Jensenius, J C; Heegaard, C W.

    In: Journal of Dairy Science, Vol. 94, No. 5, 2011, p. 2159-2170.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human α-lactalbumin. / Brinkmann, C R; Thiel, S; Larsen, M K; Petersen, T E; Jensenius, Jens Christian; Heegaard, C W.

    In: Indian Journal of Dairy Science, Vol. 94, No. 5, 2011, p. 2159-2170.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2010
  39. Published

    BAMLET – cytotoxicity and an alternative preparation method . / Brinkmann, Christel Rothe; Thiel, Steffen; Jensenius, Jens Christian; Heegaard, Christian Würtz; Petersen, Torben Ellebæk.

    2010. Poster session presented at 2nd Symposium on HAMLET and tumor-killing proteins, Lund, Sweden.

    Research output: Contribution to conferencePosterResearch

  40. Published

    A complex of oleic acid and alpha lactalbumin induces cell death resembling either necrosis or apoptosis dependent on the type of cancer cell line. / Brinkmann, Christel Rothe; Thiel, Steffen; Jensenius, Jens Christian; Heegaard, Christian Würtz; Petersen, Torben Ellebæk.

    2010. Poster session presented at The 7th European Workshop on Cell Death - Death among Vikings, Tisvildeleje, Denmark.

    Research output: Contribution to conferencePosterResearch

  41. Published

    Biodistribution of 99mTc-HYNIC-lactadherin in mice - a potential tracer for visualizing apoptosis in vivo. / Falborg, Lise; Waehrens, Lasse N; Alsner, Jan; Bluhme, Henrik; Frøkiaer, Jørgen; Heegaard, Christian W; Horsman, Michael R; Rasmussen, Jan T; Rehling, Michael.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 70, No. 3, 2010, p. 209-16.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia. / Zhou, Jin; Shi, Jialan; Hou, Jinxiao; Zang, Yingmei; Rasmussen, Jan Trige; Heegaard, Christian Würtz; Gilbert, Gary E.

    In: Journal of Thrombosis and Haemostasis, Vol. 8, 2010, p. 773–782.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. 2009
  44. Published

    Bovine Lactadherin as a Calcium-independent Imaging Agent of Phosphatidylserine Expressed on the Surface of Apoptotic HeLa Cells. / Wæhrens, Lasse Neumann; Heegaard, Christian Würtz; Gilbert, Gary E.; Rasmussen, Jan Trige.

    In: Journal of Histochemistry and Cytochemistry, Vol. 57, No. 10, 2009, p. 907-914.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Measurement of phosphatidylserine exposure during storage of platelet concentrates using the novel probe lactadherin: a comparison study with annexin V. / Albanyan, Abdul-Majeed; Murphy, Michael F.; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Harrison, Paul.

    In: Transfusion, Vol. 49, 2009, p. 99-107.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. Published

    Myocadial apoptosis in an ischemic-reperfusion porcine model, and how it is influenced by occlution time and preconditioning. / Poulsen, Runa Hyldgaard; Wæhrens, Lasse Neumann; Falborg, Lise; Heegaard, Christian Würtz; Rasmussen, Jan Trige; Rehling, Michael.

    In: Hypertension, No. 5, 2009, p. 1185.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  47. Published

    Phosphatidylserine-independent platelet binding sites for factor VIII. / .Gilbert, Gary E.; Shi, Jialan; Bai, C.; Lu, J.; Rasmussen, Jan Trige; Heegaard, Christian Würtz.

    In: Journal of Thrombosis and Haemostasis. Supplement, No. 2, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  48. 2008
  49. Published

    Mælkeprotein stand-in i cellens håndtering af kolesterol : Mælkeproteinet EPV20 erstatter kolesteroltransportør og fremmer udskillelsen af kolesterol på celleniveau. / Nielsen, Gitte Krogh; Heegaard, Christian Würtz.

    In: Dansk Mejeritidende, Vol. 5, No. 121, 07.03.2008, p. 104-106.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  50. Published

    Apoptosis detection with fluorescent and radioactive lactadherin. / Wæhrens, Lasse Neumann; Falborg, Lise; Shi, Jialan; Shi, Jinan; Gilbert, Gary E.; Dickow, Jonatan Ahrens; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2008. Poster session presented at 15th Euroconference on Apoptosis, Portoroz, Slovenia.

    Research output: Contribution to conferencePosterResearch

  51. Published

    Characterization of the Milk-Derived Niemann-Pick C2 Protein. / Nielsen, Gitte Krogh; Heegaard, Christian Wurtz.

    2008. Poster session presented at 4th International Symposium: Milk Genomics & Human Health, Nappa, United States.

    Research output: Contribution to conferencePosterResearch

  52. Published

    Effects of milk proteins against rotavirus infectivity. / Bojsen, Anni; Kvistgaard, Anne S.; Kongsbak, Mikkel Bjerg; Petersen, Torben Ellebæk; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2008. Poster session presented at AU Food Research Day, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  53. Published

    Imaging of phoshatidylserine on apoptotic plasma membranes utilizing bovine lactadherin. / Wæhrens, Lasse Neumann; Shi, J.; Shi, J.; Gilbert, Gary E.; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2008. Poster session presented at 16th Euroconference on Apoptosis (ECDO), Bern, Switzerland.

    Research output: Contribution to conferencePosterResearch

  54. Published

    Lactadherin blocks thrombosis and hemostasis in vivo: correlation with platelet phosphatidylserine exposure. / Shi, Jialan; Pipe, Steven W.; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Gilbert, Gary E.

    In: Journal of Thrombosis and Haemostasis, Vol. 6, 2008, p. 1167-1174.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Plasmin digestion of photooxidized milk proteins. / Dalsgaard, Trine Kastrup; Heegaard, Christian Wurtz; Larsen, Lotte Bach.

    In: Journal of Dairy Science, Vol. 91, 2008, p. 2175-2183.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  56. Published

    Preparation and in vitro evaluation of 99mTc-HYNIC-lactadherin as a potential radioligand for apoptosis detection. / Wæhrens, Lasse Neumann; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Falborg, Lise.

    2008. Abstract from The Annual congress of the European Association of Nuclear Medicine, COPENHAGEN, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  57. Published

    Structure and function of lactadherin in relation to its ability to recognize cellular exposed PS. / Wæhrens, Lasse Neumann; Falborg, Lise; Shi, Jialan; Shi, Jinan; Petersen, Torben Ellebæk; Gilbert, Garry E; Dickow, Jonatan Ahrens; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2008. Poster session presented at 15th Euroconference on Apoptosis, Portoroz, Slovenia.

    Research output: Contribution to conferencePosterResearch

  58. 2007
  59. Published

    Biodistribution and tracer kinetics in small and large animals of 99mTc-HYNIC-lactadherin compared to 99mTc-HYNIC-annexin V. / Falborg, Lise; Wæhrens, Lasse Neumann; Alsner, Jan; Dissing, Thomas Heide; Eilersen, J; Frøkiær, Jørgen; Heegaard, Christian Wurtz; Horsman, Michael Robert; Rasmussen, Jan Trige; Nielsen, Søren Steen; Rehling, Michael.

    In: European Journal of Nuclear Medicine and Molecular Imaging, 2007, p. S395.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  60. Published

    Cytotoxic activity of a bovine α-Lactalbumin:Oleic acid complex. / Brinkmann, Christel Rothe; Thiel, Steffen; Heegaard, Christian Wurtz; Petersen, Torben Ellebæk.

    2007. Poster session presented at Proteins killing tumor cells, Leiden, Netherlands.

    Research output: Contribution to conferencePosterResearch

  61. Published

    Inhibitory Activities of Bovine Macromolecular Whey Proteins on Rotavirus Infections In Vitro and In Vivo. / Bojsen, Anni; Buesa, Javier; Montava, Rebeca; Kvistgaard, Anne Staudt; Kongsbak, Mikkel Bjerg; Petersen, Torben Ellebæk; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    In: Journal of Dairy Science, Vol. 90, 2007, p. 66-74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    LACTADHERIN IS MORE SENSITIVE THAN ANNEXIN-V AT DETECTING PHOSPHATIDYLSERINE EXPOSURE WITHIN PLATELETS. / Albanyan, A.; Harrison, Poul; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Murphy, Mike.

    In: Journal of Thrombosis and Haemostasis, Vol. 5 Supplement 2, No. P-T-342, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  63. Published

    Preparation and in vitro evaluation of 99mTc-labelled bovine lactadherin as a novel radioligand for apoptosis detection. / Wæhrens, Lasse Neumann; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Falborg, Lise.

    In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 50, 2007, p. 211.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  64. Published

    Procoagulant function and phosphatidylserine distribution on immortilized acute prolmyelotic leukemia cells. / Shi, J.; Heegaard, Christian Wurtz; Rasmussen, Jan Trige; Gilbert, Gary E.

    In: Blood, 2007, p. 641A.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  65. Published

    RELATIONSHIP OF PROCOAGULANT ACTIVITY TO PHOSPHATIDYLSERINE EXPOSURE ON IMMORTALIZED ACUTE PROMYELOCYTIC LEUKEMIA CELLS. / Shi, Jialan; Heegaard, Christian Wurtz; Rasmussen, Jan Trige; Gilbert, Gary E.

    In: Journal of Thrombosis and Haemostasis, Vol. 5, Supplement 2, No. P-W-018, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearch

  66. 2006
  67. Published

    Detection of Cellular PS-exposure by Lactadherin. / Wæhrens, Lasse Neumann; Faldborg, Lise; Shi, Jialan; Shi, Yinan; Petersen, Torben Ellebæk; Gilbert, Gary E.; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2006. Poster session presented at 3rd International Symposium, Milk Genomics & Human Health, Brüssels, Belgium.

    Research output: Contribution to conferencePosterResearch

  68. Published

    Lactadherin Detects Early Phosphatidylserine Exposure on Immortalized Leukemia Cells Undergoing Programmed Cell Death. / Shi, Jialan; Shi, Yinan; Wæhrens, Lasse Neumann; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Gilbert, Gary E.

    In: Cytometry A, Vol. 69, No. 12, 2006, p. 1193-1201.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    Regulated phosphatidylserine exposure on platelets mediates fibrin formation in hemostasis and thrombosis. / Shi, Jialan L.; Pipe, Steven W.; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Gilbert, Gary E.

    BLOOD. Vol. 106 AMER SOC HEMATOLOGY, 1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA, 2006. p. 470A-470A.

    Research output: Contribution to book/anthology/report/proceedingConference abstract in proceedingsResearch

  70. 2005
  71. Published

    Fedkuglemembranproteiner mod sygdomsfremkaldende bakterier (I). / Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    In: Maelkeritidende, Vol. 7, 2005, p. 194-195.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  72. Published

    Fedtkuglemembranproteiner mod sygdoms-fremkaldende bakterier (II). / Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    In: Maelkeritidende, Vol. 8, 2005, p. 215-218.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  73. Published

    Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. / West, David C.; Rees, Chris G.; Duchesne, Laurence; Patey, Susannah J.; Terry, Carla J.; Turnbull, Jeremy E.; Delehedde, Maryse; Heegaard, Christian Wurtz; Allain, Fabrice; Vanpouille, Christophe; Ron, Dina; Fernig, David G.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 13457-13464.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  74. Published
  75. Published

    Potential beneficial effects of milk proteins against rotavirus infectivity. / Kvistgaard, Anne S.; Petersen, Torben Ellebæk; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2005. Poster session presented at The 2nd International Symposium on Milk Genomics & Human Health, Napa,CA, United States.

    Research output: Contribution to conferencePosterResearch

  76. Published

    Potential beneficial effects of milk proteins against rotavirus infectivity. / Rasmussen, Jan Trige; Kvistgaard, Anne S.; Pallesen, Lone T.; Petersen, Torben Ellebæk; Heegaard, Christian Wurtz.

    2005. Abstract from Conference on: Milk products and components in health and disease, Iceland.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  77. Published

    Purification of Bioactive Milk Proteins. / Heegaard, Christian Wurtz; Rasmussen, Jan Trige; Sørensen, Esben Skipper; Hobley, Timothy J.; Tennefors, Catharina; Lihme, Allan; Albertsen, Kristian; Petersen, Torben Ellebæk.

    2005. Poster session presented at The 2nd International Symposium on Milk Genomics & Human Health, Napa,CA, United States.

    Research output: Contribution to conferencePosterResearch

  78. Published

    Regulated phosphatidylserine exposure on platelets mediates fibrin formation in hemostasis and thrombosis. / Shi, Jialan L.; Pipe, Steven W.; Rasmussen, Jan Trige; Heegaard, Christian Wurtz; Gilbert, Gary E.

    Blood. 106 (470A). ed. 2005. p. abstract 1645.

    Research output: Contribution to book/anthology/report/proceedingConference abstract in proceedingsResearch

  79. Published

    Structural and functional studies of lactadherin: A role as potent anticoagulant molecule or as a non-invasive marker for apoptotic cells? / Wæhrens, Lasse Neumann; Petersen, Torben Ellebæk; Heegaard, Christian Wurtz; Rasmussen, Jan Trige.

    2005. Poster session presented at The 2nd International Symposium on Milk Genomics & Human Health, Napa, CA, United States.

    Research output: Contribution to conferencePosterResearch

  80. Published

    Videregående Biokemi : Vejledning og Rapport til Øvelserne B og C. / Petersen, Torben Ellebæk; Rasmussen, Jan Trige; Fedosov, Sergey; Sørensen, Esben Skipper; Heegaard, Christian Wurtz.

    2005.

    Research output: Book/anthology/dissertation/reportCompendium/lecture notes

  81. 2004
  82. Published

    Afslutningsrapport for FØTEK 3 projekt: "MUC1's virkning som bakteriel receptoranalog" / Heegaard, C.W.

    Mejeriernes ForskningsFond, 2004.

    Research output: Book/anthology/dissertation/reportReport

  83. Published

    EPV20 - nyt bioaktivt mælkeprotein involveret i kolesterol-metabolisme. / Heegaard, C.W.

    In: Maelkeritidende, No. 15, 2004, p. -.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearch

  84. Published

    Gunstig virkning af et højmolekylært valleprodukt mod rotavirusinduceret diaré. / Heegaard, Christian Würtz.

    In: Maelkeritidende, Vol. 117, No. 1, 2004, p. 7-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  85. Published

    In vitro digestion of novel milk protein ingredients for use in infant formulas: Research on biological functions. / Chatterton, D.E.W.; Rasmussen, J.T.; Heegaard, C.W.; Sørensen, E.S.; Petersen, T.E.

    In: Trends Food Sci. Tech., Vol. 15, 2004, p. 373-383.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. Published

    Inhibitory effects of human and bovine milk constituents on rotavirus infections. / Kvistgaard, A.S.; Pallesen, L.T.; Arias, C.F.; Lopez, S.; Petersen, T.E.; Heegaard, C.W.; Rasmussen, J.T.

    In: J. Dairy Sci., Vol. 87, 2004, p. 4088-4096.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  87. Published

    Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature. / Shi, J.; Heegaard, C.W.; Rasmussen, J.T.; Gilbert, G.E.

    In: Biochim. Biophys. Acta., Vol. 1667, 2004, p. 82-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  88. Published

    Reversible exposure of phosphatidylserine on thrombin-stimulated platelets detected by binding of lactadherin. / Shi, J.; Rasmussen, J.T.; Heegaard, C.W.; Gilbert, G.E.

    2004. Paper presented at [3537] The American Society of Hematology 46th Annual Meeting, December 4-7, 2004 San Diego, California, .

    Research output: Contribution to conferencePaperResearch

  89. 2003
  90. Published

    Limited exposure of phosphatidylserine on stimulated platelets is necessary for procoagulant activity and provides binding sites for lactadherin. / Gilbert, G.E.; Shi, J.; Rasmussen, J.T.; Heegaard, C.W.; Zhao, J.; Price, P.

    In: J. Thromb. Haem., Vol. Supplement, No. 1, 2003, p. -.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  91. Published

    Tetranectin binds hepatocyt growth factor and tissue-type plasminogen activator. / Westergaard, U.B.; Andersen, M.H.; Heegaard, C.W.; Fedosov, S.N.; Petersen, T.E.

    In: F E B S Journal, Vol. 270, 2003, p. 1850-1854.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  92. 2002
  93. Published

    Den livsnødvendige mælk. / Petersen, T.E.; Sørensen, E.S.; Rasmussen, J.T.; Heegaard, C.W.; Fedosov, Sergey; Berglund, L.

    In: Naturens Verden, 2002, p. 58-65.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  94. Published

    Lactadherin exhibits specificity for membranes containing phosphatidylserine. / Shi, Jialan; Heegaard, Christian Wurtz; Rasmussen, Jan Trige; Gilbert, Gary E.

    In: Blood, No. 11, 2002, p. 96B.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference articleResearchpeer-review

  95. 2001
  96. Published

    Thermal inactivation kinetics of bovine cathepsin D. / Hayes, M.G.; Hurley, M.J.; Larsen, L.B.; Heegaard, C.W.; Magboul, A.A.A.; Oliveira, J.C.; McSweeney, P.L.H.; Kelly, A.L.

    In: J. Dairy Res., Vol. 68, 2001, p. 267-276.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  97. 2000
  98. Published

    Bovine milk procathepsin D: presence and activity in heated milk and in extracts of rennet-free UF-feta cheese. / Larsen, L.B.; Wium, H.; Benfeldt, C.; Heegaard, C.W.; Ardö, Y.; Qvist, K.B.; Petersen, T.E.

    In: International Dairy Journal, Vol. 10, 2000, p. 67-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    Structural characterization of the fibroblast growth factor binding protein purified from bovine prepartum mammary gland secretion. / Lametsch, R.; Rasmussen, J.T.; Johnsen, L.B.; Purup, S.; Sejrsen, K.; Petersen, T.E.; Heegaard, C.W.

    In: Journal of Biological Chemistry, Vol. 275, 2000, p. 19469-19474.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. 1999
  101. Published

    Identification and characterization of new milk proteins. / Petersen, T.E.; Rasmussen, L.K.; Berglund, L.; Sørensen, E.S.; Rasmussen, J.T.; Heegaard, C.W.; Fedoxov, S.N.; Johnsen, L.B.; Andersen, M.H.; Larsen, L.B.; Benfeldt, C.

    Dairy Science and Technology: Proceedings of 25th International Dairy Congress. Århus : The Danish National Committee of IDF, 1999. p. 194-199.

    Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

  102. 1998
  103. Published

    A refined kinetic analysis of plasminogen activation by recombinant bovine tissue-type plasminogen activator indicates two interconvertible activator forms. / Johnsen, Laust B.; Ravn, Peter; Petersen, Torben E.; Rasmussen, Lone K.; Heegaard, Christian Wurtz; Rasmussen, Jan Trige; Benfeldt, Connie; Fedosov, Sergey.

    In: Biochemistry, Vol. 37, 1998, p. 12631-12639.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. Published

    Distribution of plasminogen activator forms in different fractions of buffalo milk. / Fantuz, Francesco; Baldi, Antonella; DellOrto, Vittorio; Polidori, Franco; Rossi, Carlos S.; Politis, Ioannis; Heegaard, Christian Wurtz.

    In: Journal of Dairy Research, Vol. 65, 1998, p. 521-527.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  105. 1997
  106. Published

    Breast carcinoma epithelial cells express a very low density lipoprotein receptor variant lacking the olinked glycosylation domain encoded by exon 16, but with normal binding activity for serine proteinase/serpin complexes and m, 40,000 receptor associated protein. / Martensen, Pia M.; Rettenberger, Peter M.; Christensen, Anni; Oka, Kazuhiro; Christensen, Lise; Petersen, Helle H.; Chan, Lawrence; Heegaard, Christian W.; Andreasen, Peter A.

    In: Fibrinolysis and Proteolysis, Vol. 11, No. SUPPL. 3, 01.12.1997.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. Published

    Breast carcinoma epithelial cells express a very low-density lipoprotein receptor variant lacking the O-linked glycosylation domain encoded by exon 16, but with full binding activity for serine proteinase/serpin complexes and Mr-40,000 receptor-associated protein. / Martensen, P M; Oka, K; Christensen, L; Rettenberger, P M; Petersen, H H; Christensen, A; Chan, L; Heegaard, C W; Andreasen, P A.

    In: European Journal of Biochemistry, Vol. 248, No. 2, 01.09.1997, p. 583-91.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  108. Published

    Binding of plasminogen and tissue-type plasminogen activator to dimeric αs2-casein accelerates plasmin generation. / Heegaard, Christian Wurtz; Andreasen, Peter; Petersen, Torben E.; Rasmussen, Lone K.

    In: Fibrinolysis & proteolysis, Vol. 11, 1997, p. 29-36.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. Published

    Breast carcinoma epithelial cells express a very low density lipoprotein receptor variant lacking the O-linked glycosylation domain encoded by exon 16, but with full binding activity for serine proteinase/serpin complex and Mr 40,000 receptor associated protein. / Martensen, Pia Møller; kazuhiro, Oka; Rettenberger, Peter M.; Petersen, Helle H.; Christensen, Anni; Lawrence, Chang; Heegaard, Christian Wurtz; Andreasen, Peter.

    In: F E B S Journal, Vol. 248, 1997, p. 583-591.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  110. Published

    Dimeric alphas2-casein, a novel matrix for tissue-type plasminogen activator catalyzed plasminogen activation. / Heegaard, Christian Wurtz; Andreasen, Peter; Petersen, Torben Ellebæk; Rasmussen, Lone K.

    In: Livestock Science, No. 1-2, 1997, p. 149.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference articleResearchpeer-review

  111. Published

    Specificity of serine proteinase/serpin complex binding to very low density lipoprotein receptor and α2-macroglobulin receptor /LDL-receptor-related protein. / Kasza, Aneta; Petersen, Helle H.; Heegaard, Christian Wurtz; Oka, Kazuhiro; Christensen, Anni; Dubin, Adam; Chan, Lawrence; Andreasen, Peter.

    In: F E B S Journal, Vol. 248, 1997, p. 270-281.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  112. Published

    The plasminogen activation system in human milk. / Heegaard, Christian Wurtz; Larsen, Lotte Bach; Rasmussen, Lone K.; Højberg, Karen-Elise; Petersen, Torben E.; Andreasen, Peter.

    In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 25, 1997, p. 159-166.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  113. 1996
  114. Published

    Binding and endocytosis of plasminogen activator/ serpin complexes by very low density lipoprotein receptor. / Heegaard, Christian W.; Kasza, Aneia; Petersen, Helle H.; Simonsen, Anna C.W.; Oka, Kazuhiro; Chan, Lawrence; Andreasen, Peter A.

    In: Fibrinolysis, Vol. 10, No. SUPPL. 3, 01.12.1996.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  115. Published

    Immunohistochemical localization of urokinase‑type plasminogen activator, type‑1 plasminogen activator inhibitor, urokinase receptor and alpha(2)‑macroglobulin receptor in human breast carcinomas. / Christensen, Lise; Wiborg Simonsen, Anna Carina; Heegaard, Christian Wurtz; Moestrup, Søren Kragh; Andersen, Johan A.; Andreasen, Peter.

    In: International Journal of Cancer, Vol. 66, 1996, p. 441-452.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  116. Published

    Synthesis of plasminogen activator inhibitor 1 by bovine mammary epithelial and myoepithelial cell lines. / Zavizion, Boris; Heegaard, Christian Wurtz; White, Jeffery H.; Cheli, Federcia; Politis, Ioannis.

    In: Journal of Dairy Research, Vol. 63, 1996, p. 451-458.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  117. 1995
  118. Published

    Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex. / Heegaard, Christian Wurtz; Wiborg Simonsen, Anna Carina; Oka, Kazuhiro; Kjøller, Lars; Christensen, Anni; Madsen, Bente; Ellgaard, Lars; Chan, Lawrence; Andreasen, Peter.

    In: Journal of Biological Chemistry, Vol. 270, 1995.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  119. 1994
  120. Published

    Plasminogen activators in bovine milk during mastitis, an inflammatory disease. / Heegaard, Christian Wurtz; Christensen, Tove; Rasmussen, Morten Dam; Benfeldt, Connie; Einer-Jensen, Niels; Sejrsen, Kristen; Petersen, Torben E.; Andreasen, Peter.

    In: Fibrinolysis & proteolysis, Vol. 8, 1994, p. 22-30.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  121. Published

    Production of various forms of plasminogen activator and plasminogen activator inhibitor by cultured mammary epithelial cells. / Heegaard, Christian W.; H. White, Jeffery; Zavizion, Boris; D. Turner, Jeffery; Politis, Ioannis.

    In: Journal of Dairy Science, Vol. 77, 1994, p. 2949-2958.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  122. Published

    The plasminogen activation system in bovine milk: differential localization of tissue‑type plasminogen activator and urokinase in milk fractions is caused by binding to casein and urokinase receptor. / Heegaard, Christian Wurtz; K. Rasmussen, Lone; Andreasen, Peter.

    In: B B A - Molecular Cell Research, Vol. 1222, 1994, p. 45-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  123. Published

    Very low density lipoprotein receptor from mammary gland and mammary epithelial cell lines binds and mediates endocytosis of M(r) 40,000 receptor associated protein. / Wiborg Simonsen, Anna Carina; Heegaard, Christian Wurtz; Rasmussen, Lone K.; Ellgaard, Lars; Kjøller, Lars; Christensen, Anni; Etzerodt, Michael; Andreasen, Peter.

    In: F E B S Letters, Vol. 354, 1994, p. 279-283.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  124. 1993
  125. Published

    Interconversions between active, inert and substrate forms of denatured/refolded type‑1 plasminogen activator inhibitor. / Munch, Mette; Heegaard, Christian Wurtz; Andreasen, Peter.

    In: B B A - Proteins and Proteomics, Vol. 1202, 1993, p. 29-37.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  126. 1991
  127. Published

    Type‑1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive center‑cleaved forms with thermal stability and monoclonal antibodies. / Munch, Mette; Heegaard, Christian Wurtz; Jensen, Poul Henning; Andreasen, Peter.

    In: F E B S Letters, Vol. 295, 1991, p. 102-106.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  128. 1990
  129. Published

    Monomeric state and Ca2+ transport by sarcoplasmic-reticulum Ca2+-ATPase, reconstituted with an excess of phospholipid. / Heegaard, Christian Wurtz; le Maire, Marc; Gulik-Krzywicki, Tadeusz; Møller, Jesper Vuust.

    In: Journal of Biological Chemistry, Vol. 265, No. 20, 1990, p. 12020-12028.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review