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About Aarhus University
Christian Kanstrup Holm
Professor
Department of Biomedicine - Forskning og uddannelse, Skou-bygningen
Høegh-Guldbergs Gade 10
building 1115, 222
8000 Aarhus C
Denmark
Phone: +4520968754
Mobile: +4520968754
- Published
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, D., Farahani, E., Thyrsted, J., Blay-Cadanet, J., Herengt, A., Idorn, M., Hait, A., Hernaez, B., Knudsen, A., Iversen, M. B., Schilling, M., Jørgensen, S. E., Thomsen, M., Reinert, L. S., Lappe, M., Hoang, H-D., Gilchrist, V. H., Hansen, A. L., Ottosen, R., Nielsen, C. G., & 18 othersMøller, C., van der Horst, D., Peri, S., Balachandran, S., Huang, J., Jakobsen, M., Svenningsen, E. B., Poulsen, T. B., Bartsch, L., Thielke, A. L., Luo, Y., Alain, T., Rehwinkel, J., Alcamí, A., Hiscott, J., Mogensen, T. H., Paludan, S. R. & Holm, C. K., Oct 2020, In: Nature Communications. 11, 1, 12 p., 4938.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
- Published
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming
Olagnier, D., Brandtoft, A. M., Gunderstofte, C., Villadsen, N. L., Krapp, C., Thielke, A. L., Laustsen, A., Peri, S., Hansen, A. L., Bonefeld, L., Thyrsted, J., Bruun, V., Iversen, M. B., Lin, L., Artegoitia, V. M., Su, C., Yang, L., Lin, R., Balachandran, S., Luo, Y., & 14 othersNyegaard, M., Marrero, B., Goldbach-Mansky, R., Motwani, M., Ryan, D. G., Fitzgerald, K. A., O'Neill, L. A., Hollensen, A. K., Damgaard, C. K., de Paoli, F. V., Bertram, H. C., Jakobsen, M. R., Poulsen, T. B. & Holm, C. K., 29 Aug 2018, In: Nature Communications. 9, 1, 13 p., 3506.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling
Hansen, A. L., Buchan, G. J., Rühl, M., Mukai, K., Salvatore, S. R., Ogawa, E., Andersen, S. D., Iversen, M. B., Thielke, A. L., Gunderstofte, C., Motwani, M., Møller, C. T., Jakobsen, A. S., Fitzgerald, K. A., Roos, J., Lin, R., Maier, T. J., Goldbach-Mansky, R., Miner, C. A., Qian, W., & 9 othersMiner, J. J., Rigby, R. E., Rehwinkel, J., Jakobsen, M. R., Arai, H., Taguchi, T., Schopfer, F. J., Olagnier, D. & Holm, C. K., 14 Aug 2018, In: Proceedings of the National Academy of Sciences. 115, 33, p. E7768-E7775 8 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
ID: 33634