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Charlotte Lauridsen

Professor

Profile photoCharlotte Lauridsen
Professor
Department of Animal Science - Health
Blichers Allé 20
D25, 3305
8830 Tjele
Denmark
Email: charlotte.lauridsen@anis.au.dk
Phone: +4587158019
Web: http://pure.au.dk/portal/da/charlotte.lauridsen@anis.au.dk

Profile

My research activities are primarily concerned on nutrition and physiology of animal husbandry with focus on the importance of vitamins (vitamin E, A, C og D), lipids, fatty acids, natural and synthetic antioxidants and selected minerals for especial monogastric animals liveability, health, reproduction, nutrient utilisation, and product quality. The research involves basic and applied physiological investigations with special emphasis on the digestion, absorption, metabolism, and utilisation of these nutrients, and the applied methods involve measurements of especially fatty acids and fat-soluble vitamins within the whole spectre from cell- to whole animal level. One of the major interests is the importance of n-3 and n-6 fatty acids and vitamin E for the resistance against infectious diseases, and the area comprises both humoral- and cell-mediated immunological measurements, including eicosanoids and inflammatory markers. The working area covers in addition the application of animal models (pigs and rats) for humans, for instance studies regarding the importance of organic food and human health; the interaction between diet and therapies for patients whose health is compromised by infectious diseases; and investigations on the nutritional quality of food and health-potential characteristics.

 

H-index

Web of Science: 24
Google Scholar: 27
Scopus: 26

Degrees

1998: PhD (Food Chemistry), The Royal Veterinary and Agricultural University
Frederiksberg C, Denmark. Title: “Antioxidative status in pigs and chickens
following dietary alterations, with emphasis on skeletal muscles”

1994: M.Sc. (Animal Nutrition), The Royal Veterinary and Agricultural University
Frederiksberg C, Denmark. Title: “The influence of dietary synthetic antioxidants
(ethoxyquin and butylhydroxytoluene) on broilers.


Positions

2018-: Professor in nutritional immunology, Dept. of Animal Science, Faculty of Science and Technology, Aarhus University.
2012-:Head of Research section for Immunology and Microbiology, Dept. of Animal Science, Faculty of Science and Technology, Aarhus University.

2007-2017: Senior Scientist, Animal Science, Aarhus University.
2001-2006: Senior Scientist, Danish Institute of Agricultural Sciences, Dept. Animal Health, Welfare and Nutrition.
1998-2001: Scientist, Danish Institiute of Agricultural Sciences, Dept. Animal Health, Welfare and Nutrition.
1995-1998: PhD student, Danish Institute of Agricultural Sciences, Dept. of Product Quality
1994-1995: Research training fellow, Department of Nutrition, University College Cork,
Ireland.

Maternity leave: 6 months (2007) and 6.5 months (2010)

Research training abroad

2007-2008: Div. of Veterinary Pathology, Infection and Immunity, School of Clinical
Veterinary Science, Bristol University, UK, 7 months. Immunohistochemistry.
1999: Linus Pauling Institute, Oregon State University, Oregon, USA, 8 months. Bioavailability of stereochemical forms of vitamin E using LC/MS/MS.
1994-1995: University College Cork, Ireland. Oxidative reactions in meat and cell membranes.

Research profile (most focus on pigs)

- Nutritional immunology and infection biology
- Animal models for humans 
- Basic and applied lipid nutrition
- Vitamins (major focus on vitamin A, D, E, and C) and antioxidants
- Fatty acids (major focus on n-6 and n-3), eicosanoids and inflammatory markers

Boards

2015-: Vitamin Advisory Board, DSM
2013-2016: President of the Pig Commission of EAAP

List of publications

https://pure.au.dk/portal/da/persons/charlotte-lauridsen(892b1da6-ebd2-456b-b88e-0d709e529b1c)/publications.html

Publications (last five years)

Functional in vitro screening of probiotic strains for inoculation of piglets as a prophylactic measure towards Enterotoxigenic Escherichia coli infection. / Hansen, Lea Hübertz Birch; Nielsen, B; Boll, E J; Skjøt-Rasmussen, L; Wellejus, A; Jørgensen, L ; Lauridsen, Charlotte; Canibe, Nuria.

In: Journal of Microbiological Methods, Vol. 180, 106126, 01.2021.

Antibacterial and immunomodulatory effects of Pheromonicin-NM on Escherichia coli-challenged bovine mammary epithelial cells. / Yang, Guiyan; Yue, Yuan; Li, Dan; Duan, Cong; Qiu, Xiaoqing; Zou, Yunjing; Zhu, Yaohong; Lauridsen, Charlotte; Wang, Jiufeng.

In: International Immunopharmacology, Vol. 84, 106569, 07.2020.

Effects of Dietary Fatty Acids on Gut Health and Function of Pigs Pre- and Post-Weaning. / Lauridsen, Charlotte.

In: Journal of Animal Science, Vol. 98, No. 4, skaa086, 01.04.2020.

Effects of dietary hemp seed oil to sows on fatty acid profiles, nutritional and immune status of piglets. / Vodolazska, D.; Lauridsen, C.

In: Journal of Animal Science and Biotechnology, Vol. 11, 28, 03.2020.

Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets. / Guthrie, Gregory; Stoll, Barbara; Chacko, Shaji; Lauridsen, Charlotte; Plat, Jogchum ; Burrin, Douglas G.

In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 318, No. 1, 2020, p. G41-G52.

From oxidative stress to inflammation : redox balance and immune system. / Lauridsen, Charlotte.

In: Poultry Science, Vol. 98, No. 10, 10.2019, p. 4240-4246.

Targeting gut microbiota and barrier function with prebiotics to alleviate autoimmune manifestations in NOD mice. / Hansen, Camilla H.F.; Larsen, Christian S.; Petersson, Henriette O.; Zachariassen, Line F.; Vegge, Andreas; Lauridsen, Charlotte; Kot, Witold; Krych, Łukasz; Nielsen, Dennis S.; Hansen, Axel K.

In: Diabetologia, Vol. 62, No. 9, 09.2019, p. 1689-1700.

Preterm Birth Has Effects on Gut Colonization in Piglets Within the First 4 Weeks of Life. / Kamal, Shamrulazhar Shamzir; Andersen, Anders Daniel; Krych, Lukasz; Lauridsen, Charlotte; Sangild, Per Torp; Thymann, Thomas; Nielsen, Dennis Sandris.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 68, No. 5, 2019, p. 727-733.

Effects of alpha-(1,2)-fucosyltransferase genotype variants on plasma metabolome, immune responses and gastrointestinal bacterial enumeration of pigs pre- and postweaning. / Poulsen, Ann Sofie Riis; Luise, Diana; Curtasu, Mihai Victor; Sugiharto, Sugiharto; Canibe, Nuria; Trevisi, Paolo; Lauridsen, Charlotte.

In: PLOS ONE, Vol. 13, No. 8, e0202970, 01.08.2018.

Effect of vitamin D treatments on plasma metabolism and immune parameters of healthy dairy cows. / Yue, Yuan; Hymøller, Lone; Jensen, Søren Krogh; Lauridsen, Charlotte.

In: Archives of Animal Nutrition, Vol. 72, No. 3, 04.05.2018, p. 205-220.

The influence of selenium and selenoproteins on immune responses of poultry and pigs. / Dalgaard, Tina S.; Briens, Mickaël; Engberg, Ricarda M.; Lauridsen, Charlotte.

In: Animal Feed Science and Technology, Vol. 238, 01.04.2018, p. 73-83.

Impact of Bacillus spp. spores and gentamicin on the gastrointestinal microbiota of suckling and newly weaned piglets. / Poulsen, Ann Sofie Riis; Jonge, Nadieh de; Nielsen, Jeppe Lund; Højberg, Ole; Lauridsen, Charlotte; Cutting, Simon M.; Canibe, Nuria.

In: PLOS ONE, Vol. 13, No. 11, 01.01.2018, p. e0207382.

Influence of silver nanoparticles on growth and health of broiler chickens after infection with Campylobacter jejuni. / Vadalasetty, Krishna Prasad; Lauridsen, Charlotte; Engberg, Ricarda Margarete; Vadalasetty, Radhika; Kutwin, Marta ; Chwalibog, André; Sawosz, Ewa.

In: B M C Veterinary Research, Vol. 14, 2018.

Gut microbiota composition may relate to weight loss rate in obese pet dogs. / Kieler, Ida Nordang; Kamal, Shamrulazhar; Vitger, Anne Désiré; S. Nielsen, Dennis; Lauridsen, Charlotte; Bjørnvad, Charlotte R.

In: Veterinary Medicine and Science, Vol. 3, No. 4, 11.2017, p. 252-262.

Immunomodulating effects of probiotics, prebiotics and synbiotics for pig gut health. / Roselli, Marianna; Pieper, Robert; Rogel-Gaillard, Claire; de Vries, Hugo; Bailey, Mick ; Schmidt, Hauke; Lauridsen, Charlotte.

In: Animal Feed Science and Technology, Vol. 233, 11.2017, p. 104-119.

Supplementation with Lactobacillus paracasei or Pediococcus pentosaceus does not prevent diarrhea in netonatal pigs infected with Escherichia coli F18. / Andersen, A D; Cilieborg, Malene Skovsted; Lauridsen, Charlotte; Mørkbak, A L; Sangild, P.T.

In: British Journal of Nutrition, Vol. 118, No. 2, 28.07.2017, p. 109-120.

Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs. / Li, Yanqi; Duc Ninh Nguyen; de Waard, Marita; Christensen, Lars; Zhou, Ping; Jiang, Pingping; Sun, Jing; Bojesen, Anders Miki; Lauridsen, Charlotte; Lykkesfeldt, Jens; Dalsgaard, Trine Kastrup; Bering, Stine Brandt; Sangild, Per Torp.

In: Journal of Nutrition, Vol. 147, No. 6, 06.2017, p. 1121-1130.

Effects of experimentally increased protein supply to postpartum dairy cows on plasma protein synthesis, rumen tissue proliferation, and immune homeostasis. / Larsen, Mogens; Røntved, Christine Maria; Theil, Peter Kappel; Khatun, Mona ; Lauridsen, Charlotte; Kristensen, Niels Bastian.

In: Journal of Animal Science, Vol. 95, No. 5, 05.2017, p. 2097-2110.

Effects of vitamin D and its metabolites on cell viability and Staphylococcus aureus invasion in bovine mammary epithelial cells. / Yue, Yuan; Hymøller, Lone; Jensen, Søren Krogh; Lauridsen, Charlotte; Purup, Stig.

In: Veterinary Microbiology, Vol. 203, 05.2017, p. 245-251.

Purified natural pig immunoglobulins can substitute dietary zinc in reducing piglet post weaning diarrhoea. / Hedegaard, Chris Juul; Lauridsen, Charlotte; Hedegaard, Peter M H.

In: Veterinary Immunology and Immunopathology, Vol. 186, 04.2017, p. 9-14.

The microbial community of the gut differs between piglets fed sow milk, milk replacer or bovine colostrum. / Poulsen, Ann-Sofie Riis; de Jonge, Nadieh; Sugiharto, Sugiharto; Nielsen, Jeppe L; Lauridsen, Charlotte; Canibe, Nuria.

In: British Journal of Nutrition, Vol. 117, No. 7, 04.2017, p. 964-978.

Multi-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions. / Guthrie, Gregory; Kulkarni, Madhulika; Vlaardingerbroek, Hester; Stoll, Barbara; Ng, Kenneth; Martin, Camilia; Belmont, John; Hadsell, Darryl; Heird, William; Newgard, Christopher B.; Olutoye, Oluyinka O; van Goudoever, Johannes; Lauridsen, Charlotte; He, Xingxuan; Schuchman, Edward H.; Burrin, Douglas G.

In: Journal of Lipid Research, Vol. 57, No. 9, 09.2016, p. 1696-1711.

Vitamin E plasma kinetics in swine show low bioavailability and short half-life of all-rac-α-tocopheryl acetate1,2. / van Kempen, T A T G; Reijersen, M H ; de Bruijn, C; De Smet, S; Michiels, J; Traber, M G; Lauridsen, Charlotte.

In: Journal of Animal Science, Vol. 94, No. 10, 09.2016, p. 4188-4195.

Dietary Chlorella supplementation effect on immune responses and growth performances of broiler chickens exposed to post hatch holding time. / Sugiharto, S; Lauridsen, Charlotte.

In: Livestock Research for Rural Development, Vol. 28, No. 7, 119, 07.2016.

Vitamin E in new Generation Lipid Emulsions Protects Against Parenteral Nutrition-Associated Liver disease in Parenteral Nutrition-Fed Preterm Pigs. / Kenneth, Ng; Stoll, Barbara; Chacko, Shaji; Saenz de Pipaon, Miquel; Lauridsen, Charlotte; Grey, Matthew; Squires, E James ; Marini, Juan ; Zamora, Irving; Oluyinka, Olutoye; Burrin, Douglas G.

In: Journal of Parenteral and Enteral Nutrition, Vol. 40, 07.2016, p. 656–671.

Enteral but not parenteral antibiotics enhance gut function and prevent necrotizing enterocollitis in forumula-fed newborn preterm pigs. / Birck, Malene M; Nguyen, Duc Ninh; Cilieborg, Malene Skovsted; Kamal, Shamrulazhar; S. Nielsen, Dennis; Damborg, Peter; Olsen, John E; Lauridsen, Charlotte; Sangild, Per Torp; Thymann, Thomas.

In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 310, No. 5, 03.2016, p. G323-G333.

How to understand the complexity of product quality and the challenges in differentiating between organically and conventionally grown products—exemplified by fresh and heat-processed carrots (Daucus carota L.). / Seljåsen, Randi; Kristensen, Hanne Lakkenborg; Kretzschmar, Ursula; Birlouez-Aragone, Inès; Paoletti, Flavio; Lauridsen, Charlotte; Wyss, Gabriela S; Busscher, Nicolaas; Mengheri, Elena; Sinesio, Fiorella; Zanoli, Raffaele; Vairo, Daniela; Beck, Alexander; Kahl, Johannes.

In: Organic Agriculture - Official journal of The International Society of Organic Agriculture Research, Vol. 6, No. 1, 03.2016, p. 31-47.

Vitamin D3 and 25-hydroxyvitamin D3 in pork and their relationship to vitamin D status in pigs. / Burild, Anders; Lauridsen, Charlotte; Faqir, Nasrin; Sommer, Helle M; Jakobsen, Jette .

In: Journal of Nutritional Science, Vol. 5, e3, 01.2016.

Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs. / Shen, Rene L; Thymann, Thomas; Østergaard, Mette V; Støy, Ann Cathrine Findal; Krych, Łukasz ; S. Nielsen, Dennis; Lauridsen, Charlotte; Hartmann, Bolette; J. Holst, Jens; Burrin, Douglas G; Sangild, Per T.

In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 309, No. 5, 09.2015, p. G310-G323.

Gastrointestinal ecosystem and immunological responses in E.coli challenged pigs after weaning fed liquid diets containing whey permeate fermented with different lactic acid bacteria. / Sugiharto, Sugiharto; Lauridsen, Charlotte; Jensen, Bent Borg.

In: Animal Feed Science and Technology, Vol. 207, 09.2015, p. 278-282.

Effect of bovine colostrum feeding in comparison with milk replacer and natural feeding on the immune responses and colonisation of enterotoxigenic Escherichia coli in the intestinal tissue of piglets. / Sugiharto, Sugiharto; Poulsen, Ann-Sofie Riis; Canibe, Nuria; Lauridsen, Charlotte.

In: British Journal of Nutrition, Vol. 113, No. 6, 2015, p. 923-934.

Influence of genotype and feeding strategy on pig performance, plasma concentrations of micro nutrients, immune responses and faecal microbiota composition of growing-finishing pigs in a forage-based system. / Kongsted, Anne Grete; Nørgaard, Jan Værum; Jensen, Søren Krogh; Lauridsen, Charlotte; Juul-Madsen, Helle Risdahl; Norup, Liselotte Rothmann; Engberg, Ricarda M; Horsted, Klaus; Hermansen, John Erik.

In: Livestock Science, Vol. 178, 2015, p. 263-271.

Prevention of enterotoxigenic Escherichia coli infections in pigs by dairy-based nutrition. / Sugiharto, Sugiharto; Jensen, Bent Borg; Jensen, Karin Hjelholt; Lauridsen, Charlotte.

In: CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, Vol. 10, No. 052, 2015.

Neonatal piglet survival: impact of sow nutrition around parturition on fetal glycogen deposition and production and composition of colostrum and transient milk. / Theil, Peter Kappel; Lauridsen, Charlotte; Quesnel, H.

In: Animal, Vol. 8, No. 7, 07.2014, p. 1021-1030.

Plasma metabolomic profiles and immune responses of piglets after weaning and challenge with E. coli. / Sugiharto, Sugiharto; Hedemann, Mette Skou; Lauridsen, Charlotte.

In: Journal of Animal Science and Biotechnology, Vol. 5, 17, 14.03.2014, p. 1-8.

Effects of oral micellized natural vitamin E (D-α-tocopherol) v. syntheric vitamin E (DL-α-tocopherol) in feed on α-tocopherol levels, stereoisomer distribution, oxidative stress and the immune response in piglets. / Amazan, D; Cordero, G; López-Bote, C J; Lauridsen, Charlotte; Rey, A I .

In: Animal, Vol. 8, No. 3, 03.2014, p. 410-419.

Triennial Growth Symposium - Establishment of the 2012 vitamin D requirements in swine with focus on dietary forms and levels of vitamin D1. / Lauridsen, Charlotte.

In: Journal of Animal Science, Vol. 92, No. 3, 03.2014, p. 910-916.

Comparison of casein and whey in diets on performance, immune responses and metabolomic profile of weaning pigs challenged with E.coli F4. / Sugiharto, Sugiharto; Jensen, Bent Borg; Hedemann, Mette Skou; Lauridsen, Charlotte.

In: Canadian Journal of Animal Science, Vol. 94, No. 3, 2014, p. 479-491.