Department of Clinical Medicine

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Charlotte Brandt Sørensen

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  1. 2022
  2. Published
    A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency. / Andersen, Olav M; Bøgh, Nikolaj; Landau, Anne M et al.
    In: Cell Reports Medicine, Vol. 3, No. 9, 100740, 09.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. 2021
  4. Published
    In vivo evidence that SORL1, encoding the endosomal recycling receptor SORLA, can function as a causal gene in Alzheimer´s Disease. / Andersen, Olav Michael; Bøgh, Nikolaj; Landau, Anne et al.
    2021.

    Research output: Working paper/Preprint › Preprint

  5. 2020
  6. Published
    Impact of Administration Time and Kv7 Subchannels on the Cardioprotective Efficacy of Kv7 Channel Inhibition. / Hansen, Jan; Johnsen, Jacob; Nielsen, Jan Møller et al.
    In: Drug Design, Development and Therapy, Vol. 14, 07.2020, p. 2549-2560.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  7. Published
    Effects of castration on atherosclerosis in Yucatan minipigs with genetic hypercholesterolemia. / Shim, Jeong T.; Schmidt, Nikolaj; Nogales, Paula et al.
    In: PLOS ONE, Vol. 15, No. 6, e0234131, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  8. 2019
  9. Published
    Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone. / Andersen, Stine; Axelsen, Julie Birkmose; Ringgaard, Steffen et al.
    In: Pulmonary Circulation, Vol. 9, No. 2, 05.2019, p. 1-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. Published
    Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome. / Dorado, Beatriz; Pløen, Gro Grunnet; Barettino, Ana et al.
    In: Cell Discovery, Vol. 5, 16, 03.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  11. 2018
  12. Published
    Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs. / Shim, Jeong; Poulsen, Christian Bo; Hagensen, Mette et al.
    In: Transgenic Research, Vol. 27, 2018, p. 484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review

  13. Published
    Production of genetically modified founder pigs as models for human diseases. / Callesen, Henrik; Liu, Ying; Pedersen, Hanne Skovsgaard et al.
    In: Reproduction, Fertility and Development, Vol. 30, No. 1, Abst. no. 23, 2018, p. 151.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review

  14. 2017
  15. Published
    Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs. / Shim, Jeong; Poulsen, Christian Bo; Hagensen, Mette K et al.
    In: JACC: Basic to translational science, Vol. 2, No. 5, 2017, p. 591-600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  16. Published
    Evaluation of porcine stem cells competence for somatic cell nuclear transfer and production of cloned animals. / Secher, Jan; Liu, Ying; Petkov, Stoyan et al.
    In: Animal Reproduction Science, Vol. 178, 2017, p. 40-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  17. 2016
  18. Published
    Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system. / Zhou, Yan; Liu, Yong; Hussmann, Dianna et al.
    In: Cellular and Molecular Life Sciences, Vol. 73, No. 13, 11.01.2016, p. 2543-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. Published
    Differences in Hypercholesterolemia and Atherogenesis Induced by Common Androgen Deprivation Therapies in Male Mice. / Poulsen, Christian Bo; Mortensen, Martin Bødtker; Koechling, Wolfgang et al.
    In: Journal of the American Heart Association, Vol. 5, No. 2, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  20. Published
    Large animal models of atherosclerosis - new tools for persistent problems in cardiovascular medicine. / Shim, Jeong; Al-Mashhadi, Rozh Husain; Sørensen, Charlotte Brandt et al.
    In: Journal of Pathology, Vol. 238, No. 2, 2016, p. 257-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. 2015
  22. Published
    Pig model for atherosclerosis. Europe Patent EP2134847, June 24, 2015. / Bentzon, Jacob Fog (Inventor); Sørensen, Charlotte Brandt (Inventor); Kragh, Peter (Inventor) et al.
    Jun 24, 2015.

    Research output: Patent

  23. Published
    Targeted Porcine Genome Engineering with TALENs. / Luo, Yonglun; Lin, Lin; Golas, Mariola Monika et al.
    Somatic Genome Manipulation : Advances, Methods and Applications. Springer New York, 2015. p. 17-33.

    Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research › peer-review

  24. 2014
  25. Published
    Efficient construction of rAAV-based gene targeting vectors by Golden Gate cloning. / Luo, Yonglun; Lin, Lin; Bolund, Lars et al.
    In: BioTechniques, Vol. 56, No. 5, 05.2014, p. 263-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  26. Published
    Absence of an intron splicing silencer in porcine Smn1 intron 7 confers immunity to the exon skipping mutation in human SMN2. / Doktor, Thomas Koed; Schrøder, Lisbeth Dahl; Andersen, Henriette Skovgaard et al.
    In: PLOS ONE, Vol. 9, No. 6, 2014, p. e98841.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  27. Published
    Efficient genome engineering using rAAV and TALENs in pigs. / Luo, Yonglun; Viuff, B M; Lin, Lin et al.
    In: Transgenic Research, Vol. 23, No. 1, 2014, p. 189-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference article › Research › peer-review

  28. 2013
  29. Published
    Pig model for atherosclerosis. United States Patent US 8,546,643. Oct 1, 2013. / Bentzon, Jacob Fog (Inventor); Sørensen, Charlotte Brandt (Inventor); Kragh, Peter (Inventor) et al.
    Oct 01, 2013.

    Research output: Patent

  30. Published
    Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant. / Al-Mashhadi, Rozh H; Sørensen, Charlotte B; Kragh, Peter M et al.
    In: Science Translational Medicine, Vol. 5, No. 166, 2013, p. 166ra1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  31. 2012
  32. Published
    Genetically modified pigs for biomedical research. / Luo, Yonglun; Lin, Lin; Bolund, Lars et al.
    In: Journal of Inherited Metabolic Disease, Vol. 35, No. 4, 2012, p. 695-713.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  33. Published
    Hypercholesterolemic minipigs created by liver-specific expression of a PCSK9 gain-of-function mutant. / Bentzon, Jacob Fog; Sørensen, Charlotte Brandt; Al-Mashhadi, Rozh Husain et al.
    In: Transgenic Research, Vol. 21, No. 4, 2012, p. 910-911.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research › peer-review

  34. Published
    Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences. / Luo, Yonglun; Bolund, Lars; Sørensen, Charlotte Brandt.
    In: Transgenic Research, Vol. 21, 2012, p. 671-676.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  35. Published
    Targeted Genome Editing by Recombinant Adeno-Associated Virus (rAAV) Vectors for Generating Genetically Modified Pigs. / Luo, Yonglun; Kofod-Olsen, Emil; Christensen, Rikke et al.
    In: Journal of Genetics and Genomics, Vol. 39, No. 6, 2012, p. 269-74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  36. 2011
  37. Published
    Final Report Pigs and Health 2007-2011. / Bendixen, Christian; Callesen, Henrik; Bolund, Lars et al.
    Højteknologifonden, 2011. 29 p.

    Research output: Book/anthology/dissertation/report › Report › Research

  38. Published
    An update on targeted gene repair in mammalian cells: methods and mechanisms. / Jensen, Nanna M; Dalsgaard, Trine; Jakobsen, Maria et al.
    In: International Journal of Biomedical Science, Vol. 18, 01.01.2011, p. 10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  39. Published
    An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones. / Luo, Yonglun; Bolund, Lars; Sørensen, Charlotte B.
    In: BMC Research Notes, Vol. 4, 2011, p. 246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  40. Published
    Comparison of gene expression and genome-wide DNA methylation profiling between phenotypically normal cloned pigs and conventionally bred controls. / Fei, Gao; Luo, Yonglun; Li, Shengting et al.
    In: P L o S One, Vol. 6, No. 10, 2011, p. e25901.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  41. Published
    High efficiency of BRCA1 knockout using rAAV-mediated gene targeting: developing a pig model for breast cancer. / Luo, Yonglun; Li, Juan; Liu, Ying et al.
    In: Transgenic Research, Vol. 20, 2011, p. 975-988.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  42. 2008
  43. Published
    High Hydrostatic Pressure Treatment of Porcine Oocytes before Handmade Cloning Improves Developmental Competence and Cryosurvival. / Du, Yutao; Lin, Lin; Schmidt, Mette et al.
    In: Cloning and Stem Cells, Vol. 10, No. 3, 2008, p. 325-330.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  44. 2005
  45. Published
    Erratum: Site-specific strand bias in gene correction using single-stranded oligonucleotides (Journal of Molecular Medicine (2005) 83 (39-49) DOI: 10.1007/s00109-004-0592-6). / Sørensen, Charlotte B.; Krogsdam, Anne Margrethe; Andersen, Marie S. et al.
    In: Journal of Molecular Medicine, Vol. 83, No. 6, 01.06.2005, p. 495-496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

  46. Published
    Site-specific strand bias in gene correction using single-stranded oligonucleotides. / Sørensen, Charlotte B; Krogsdam, Anne-Margrethe; Andersen, Marie S et al.
    In: Journal of Molecular Medicine, Vol. 83, No. 1, 2005, p. 39-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  47. 2003
  48. Published
    Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex. / Sørensen, Charlotte B; Andresen, Brage S; Jensen, Uffe B et al.
    In: Experimental Dermatology Online, Vol. 12, No. 4, 08.2003, p. 472-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  49. Published
    Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase. / Jensen, Thomas G; Sørensen, Charlotte B; Jensen, Uffe B et al.
    In: Experimental Dermatology Online, Vol. 12, No. 1, 02.2003, p. 71-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  50. 2002
  51. Published
    Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides. / Andersen, Marie S; Sørensen, Charlotte B; Bolund, Lars et al.
    In: Journal of Molecular Medicine, Vol. 80, No. 12, 2002, p. 770-781.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  52. 2001
  53. Published
    Epidermolysis bullosa simplex: molecular and functional characterisation of the mutational spectrum in Danish patients. / Sørensen, C.B.
    Århus, 2001.

    Research output: Book/anthology/dissertation/report › Ph.D. thesis

  54. 2000
  55. Published
    Epidermolysis bullosa simplex: Korrelation mellem genotype og fænotype hos danske patienter. / Sørensen, C.B.; Ladekjær-Mikkelsen, A.-S.; Andresen, B.S. et al.
    In: Ugeskrift for Laeger, Vol. 162, 2000, p. 1873-1876.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  56. Published
    Keratinsygdomme: Oversigtsartikel. / Jensen, P.K.A.; Sørensen, C.B.; Andresen, B.S. et al.
    In: Ugeskrift for Laeger, Vol. 162, 2000, p. 1867-1872.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research

  57. 1999
  58. Published
    Identification of novel and known mutations in the genes for keratin 5 and 14 in Danish patients with epidermolysis bullosa simplex: Correlation between genotype and phenotype. / Sørensen, C.B.; Ladekjær-Mikkelsen, A.-S.; Andresen, B.S. et al.
    In: J. Invest. Dermatol., Vol. 112, 1999, p. 184-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  59. 1997
  60. Published
    Cloning of the murine tetranectin gene and 5'-flanking region. / Sørensen, Charlotte Brandt; Berglund, Lars; Petersen, Torben Ellebæk.
    In: Gene, Vol. 201, No. 1-2, 12.11.1997, p. 199-202.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  61. 1995
  62. Published
    Cloning of a cDNA encoding murine tetranectin. / Sørensen, Charlotte Brandt; Berglund, Lars; Petersen, Torben Ellebæk.
    In: Gene, Vol. 152, No. 2, 23.01.1995, p. 243-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  63. 1993
  64. Published
    Determination of the disulphide bridge arrangement of bovine histidine-rich glycoprotein. / Sørensen, Charlotte Brandt; Krogh-Pedersen, H; Petersen, T E.
    In: F E B S Letters, Vol. 328, No. 3, 08.1993, p. 285-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review