Elmedal Laursen B.

2025

Abstract B024: Advancing precision medicine: A prospective feasibility study integrating ex vivo drug testing and genomic profiling to improve outcomes in children and adults with advanced cancers

Ipsen, M. B., Skjøtt, M. E., Arshadi, A., Poulsen, S. B., Carstensen, R. T., Elbæk, K. J., Korshoej, A. R., B., E. L., Sædder, E. A., Larsen, O. H., Mikkelsen, T. S., Thorsen, K., Thomsen, M. K. & Rusan, M., 1 Mar 2025, In: Cancer Research. 85, 5 supplement, B024.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

Open Access

2024

Exploring the molecular landscape of cancer of unknown primary: A comparative analysis with other metastatic cancers

Andersen, L., Christensen, D. S., Kjær, A., Knudsen, M., Andersen, A. K., Laursen, M. B., Ahrenfeldt, J., Laursen, B. E. & Birkbak, N. J., Oct 2024, In: Molecular Oncology. 18, 10, p. 2393-2406 14 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

2023

Increased morbidity evaluated on hospital contacts and prescriptions among 100,834 Danish breast cancer survivors

Fredslund, S. O., Berglund, A., Jensen, A. B., Laursen, B. E., Juul, S., Stochholm, K. & Gravholt, C. H., Jul 2023, In: Journal of Cancer Research and Clinical Oncology. 149, 7, p. 2823-2831 9 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

1 Citation (Scopus)

Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns

Sørensen, S. G., Shrikhande, A., Poulsgaard, G. A., Christensen, M. H., Bertl, J., Laursen, B. E., Hoffmann, E. R. & Pedersen, J. S., 8 Mar 2023, In: eLife. 12, 27 p., e81224.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

4 Citations (Scopus)

ProTarget: a Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on genomic profiling – a national, phase 2, prospective, multi-drug, non-randomized, open-label basket trial

Kringelbach, T., Højgaard, M., Rohrberg, K., Spanggaard, I., Laursen, B. E., Ladekarl, M., Haslund, C. A., Harsløf, L., Belcaid, L., Gehl, J., Søndergaard, L., Eefsen, R. L., Hansen, K. H., Kodahl, A. R., Jensen, L. H., Holt, M. I., Oellegaard, T. H., Yde, C. W., Ahlborn, L. B. & Lassen, U., Dec 2023, In: BMC Cancer. 23, 1, 182.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

17 Citations (Scopus)

2021

Changes in vascular function during breast cancer treatment

Fredslund, S. O., Buus, N. H., Skjold, C., Laugesen, E., Jensen, A. B. & Laursen, B. E., Nov 2021, In: British Journal of Clinical Pharmacology. 87, 11, p. 4230-4240 11 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

8 Citations (Scopus)

2019

Carcinoma of Unknown Primary Site (CUP) With Metastatic Renal-Cell Carcinoma (mRCC) Histologic and Immunohistochemical Characteristics (CUP-mRCC): Results From Consecutive Patients Treated With Targeted Therapy and Review of Literature

Overby, A., Duval, L., Ladekarl, M., Laursen, B. E. & Donskov, F., Feb 2019, In: Clinical Genitourinary Cancer. 17, 1, p. e32-e37 6 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

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19 Citations (Scopus)

58 Downloads (Pure)

Hierarchical classification of cancers of unknown primary using multi-omics data

Bavafaye Haghighi, E., Knudsen, M., Laursen, B. E. & Besenbacher, S., 1 Aug 2019, In: Cancer Informatics. 18, 16 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Open Access

13 Citations (Scopus)

Key metabolic parameters change significantly in early breast cancer survivors: An explorative PILOT study

Fredslund, S. O., Gravholt, C. H., Laursen, B. E. & Jensen, A. B., 2019, In: Journal of Translational Medicine. 17, 1, 13 p., 105.

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Open Access

24 Citations (Scopus)

Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform

King, D., Glynn, M. D., Cindric, S., Kernan, D., O’Connell, T., Hakimjavadi, R., Kearney, S., Ackermann, T., Berbel, X. M., Llobera, A., Simonsen, U., Laursen, B. E., Redmond, E. M., Cahill, P. A. & Ducrée, J., Mar 2019, In: Scientific Reports. 9, 4157.

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Open Access

7 Citations (Scopus)

2018

A Rare Case of Embryonal Carcinoma in a Patient with Turner Syndrome without Y Chromosomal Material but Mutations in KIT, AKT1, and ZNF358 Demonstrated Using Exome Sequencing

Gravholt, C. H., Dollerup, O. L., Duval, L., Mejlgaard, E., Stribolt, K., Vang, S., Laursen, B. E., Knudsen, M., Thorsen, K., Hersmus, R., Looijenga, L. H. J. & Stochholm, K., 2018, In: Sexual Development. 11, 5-6, p. 262-268 7 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

9 Citations (Scopus)

2016

Clinical Pharmacology in Denmark in 2016 - 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality

Brøsen, K., Andersen, S. E., Borregaard, J., Christensen, H. R., Christensen, P. M., Dalhoff, K. P., Damkier, P., Hallas, J., Heisterberg, J., Jessen, N., Jürgens, G., Kampmann, J. P. K., Laursen, B. E., Laursen, T., Nielsen, L. P., Poulsen, B. K., Poulsen, H. E., Andersen, L. V., Senderovitz, T. & Sonne, J., 1 Dec 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 6, p. 523-532 10 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

10 Citations (Scopus)

2014

Anti-Vascular Endothelial Growth Factor Therapy in Breast Cancer

Kristensen, T. B., Knutsson, M. L. T., Wehland, M., Laursen, B. E., Grimm, D. G., Warnke, E. & Magnusson, N. E., 2014, In: International Journal of Molecular Sciences (Online). 15, 12, p. 23024-23041 18 p.

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55 Citations (Scopus)

2012

Activation of endothelial and epithelial KCa2.3 calcium-activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles

Kroigaard, C., Dalsgaard, T., Nielsen, G., Laursen, B. E., Pilegaard, H., Köhler, R. & Simonsen, U., 17 Apr 2012, In: British Journal of Pharmacology. 167, p. 37-47

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31 Citations (Scopus)

Echocardiographic screening for pulmonary hypertension in stable COPD out-patients and NT-proBNP as a rule-out test

Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Sønderskov, L. D., Laursen, B. E., Simonsen, U. & Hilberg, O., 2012, In: C O P D. p. 505 512 p.

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21 Citations (Scopus)

2011

Pulmonary pressure reduction attenuates expression of proteins identified by lung proteomic profiling in pulmonary hypertensive rats

Østergaard, L., Honoré, B., Thorsen, L. B., Baandrup, J., Eskildsen-Helmond, Y., Laursen, B. E., Vorum, H., Mulvany, M. J. & Simonsen, U., 2011, In: Proteomics. 11, 23, p. 4492-502 11 p.

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11 Citations (Scopus)

Vaginal østrogenbehandling ved hormonfølsom brystkræft

Bak, A. M., B., E. L., Rungby, J. & B., B., 2011, In: Ugeskrift for Læger.

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1 Citation (Scopus)

2010

BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats

Thorsen, L., Eskildsen-Helmond, Y., Zibrandtsen, H., Stasch, J.-P., Simonsen, U. & B., E. L., 25 Nov 2010, In: European Journal of Pharmacology. 647, 1-3, p. 147-54 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

24 Citations (Scopus)

2008

Hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy is unaltered by long-term oral L-arginine administration

Laursen, B. E., Dam, M. Y., Mulvany, M. J. & Simonsen, U., 2008, In: Vascular Pharmacology. 49, 2-3, p. 71-6 5 p.

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11 Citations (Scopus)

Hypoxia-induced vasoconstriction in alligator (Alligator mississippiensis) intrapulmonary arteries: a role for endothelin-1?

Skovgaard, N., Zibrandtsen, H., Laursen, B. E., Simonsen, U. & Wang, T., 2008, In: Journal of Experimental Biology. 211, Pt 10, p. 1565-70 6 p.

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10 Citations (Scopus)

ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries.

Simonsen, U., Laursen, B. E. & Petersen, J. S., 2008, In: British Journal of Pharmacology. 153, 6, p. 1185-94 10 p.

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16 Citations (Scopus)

2006

Involvement of guanylyl cyclase, protein kinase A, and Na-K-ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor

Laursen, B. E., Mulvany, M. J. & Simonsen, U., 2006, In: Pulm. Pharmacol. Ther.. 19, 3, p. 179-188 10 p.

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11 Citations (Scopus)

2005

Dual impact of a nitric oxide donor, GEA 3175, in human pulmonary smooth muscle

B., E. L., Mulvany, M. J. & Simonsen, U., 2005, In: Eur. J. Pharmacol.. 516(1), p. 78-84 7 p.

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7 Citations (Scopus)

Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries

Lopez-Valverde, V., Andersen, C. U., Laursen, B. E., Mulvany, M. J. & Simonsen, U., 2005, In: J Cardiovasc Pharmacol.. 46(4), p. 422-429 8 p.

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8 Citations (Scopus)

Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries

López-Valverde, V., Andersen, C. U., Laursen, B. E., Mulvany, M. J. & Simonsen, U., 2005, In: Journal of Cardiovascular Pharmacology. 46, 4, p. 422-9 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

8 Citations (Scopus)

Elmedal Laursen B.

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