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Boe Sandahl Sørensen

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  1. 2023
  2. Published
    Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo. / Neldeborg, Signe; Soerensen, Johannes Frasez; Møller, Charlotte Thornild et al.
    In: Leukemia, Vol. 37, No. 9, 09.2023, p. 1792-1801.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  3. E-pub ahead of print
    Comparison of culture media reveals that non-essential amino acids strongly affect the phenotype of human monocyte-derived macrophages. / Antonsen, Kristian W; Friis, Henriette N; Sorensen, Boe S et al.
    In: Immunology, 08.06.2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  4. Published
    Blood tumor mutational burden and dynamic changes in circulating tumor DNA predict response to pembrolizumab treatment in advanced non-small cell lung cancer. / Stensgaard, Simone; Thomsen, Astrid; Helstrup, Sofie et al.
    In: Translational Lung Cancer Research, Vol. 12, No. 5, 05.2023, p. 971-984.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  5. Published
    Cell-free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients. / Månsson, Christoffer Trier; Meldgaard, Peter; Stougaard, Magnus et al.
    In: Molecular Oncology, Vol. 17, No. 5, 05.2023, p. 722-736.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  6. Published
    DNAfusion: an R/Bioconductor package for increased sensitivity of detecting gene fusions in liquid biopsies. / Månsson, Christoffer Trier; Andersen, Emma Roger; Parm Ulhøi, Maiken et al.
    In: BMC Bioinformatics , Vol. 24, No. 1, 131, 04.2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  7. Published
    Examination of the Functional Relationship between PD-L1 DNA Methylation and mRNA Expression in Non-Small-Cell Lung Cancer. / Larsen, Trine V; Dybdal, Nina; Daugaard, Tina F et al.
    In: Cancers, Vol. 15, No. 6, 1909, 03.2023.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  8. Published
    Circulating immune response proteins predict the outcome following disease progression of osimertinib treated epidermal growth factor receptor-positive non-small cell lung cancer patients. / Maansson, Christoffer T; Helstrup, Sofie; Ebert, Eva B F et al.
    In: Translational Lung Cancer Research, Vol. 12, No. 1, 01.2023, p. 14-26.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  9. Published
    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells. / Vad-Nielsen, Johan; Staunstrup, Nicklas Heine; Kjeldsen, Magnus Lindkvist et al.
    In: Translational Lung Cancer Research, Vol. 12, No. 1, 01.2023, p. 42-65.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  10. 2022
  11. Published
    An Extended PD-L2 Cytoplasmic Domain Results From Alternative Splicing in NSCLC Cells. / Dietz, Lisa Loksø; Furman, Natasja Toft; Larsen, Trine Vilsbøll et al.
    In: Journal of Immunotherapy, Vol. 45, No. 9, 11.2022, p. 379-388.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  12. Published
    Metabolism of 25-Hydroxy-Vitamin D in Human Macrophages Is Highly Dependent on Macrophage Polarization. / Nygaard, Rie H; Nielsen, Marlene C; Antonsen, Kristian W et al.
    In: International Journal of Molecular Sciences , Vol. 23, No. 18, 10943, 09.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  13. Published
    Tumoral PD-L1 does not impact time to treatment discontinuation in EGFR mutated non-small cell lung cancer patients treated with EGFR tyrosine kinase inhibitor-a Danish cohort study. / Gabe Dissing, Julie; Parm Ulhøi, Maiken; Sørensen, Boe Sandahl et al.
    In: Translational Lung Cancer Research, Vol. 11, No. 9, 09.2022, p. 1796–1808.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  14. Published
    Increased Soluble PD-1 Predicts Response to Nivolumab plus Ipilimumab in Melanoma. / Pedersen, Jesper Geert; Sokac, Mateo; Sørensen, Boe Sandahl et al.
    In: Cancers, Vol. 14, No. 14, 3342, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  15. Published
    The Diagnostic Value of Circulating Cell-Free HPV DNA in Plasma from Cervical Cancer Patients. / Bønløkke, Sara; Stougaard, Magnus; Sorensen, Boe Sandahl et al.
    In: Cells, Vol. 11, No. 14, 2170, 07.2022.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  16. Published
    Osimertinib in non-small cell lung cancer with uncommon EGFR-mutations: a post-hoc subgroup analysis with pooled data from two phase II clinical trials. / Eide, Inger Johanne Zwicky; Stensgaard, Simone; Helland, Åslaug et al.
    In: Translational Lung Cancer Research, Vol. 11, No. 6, 06.2022, p. 953-963.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  17. Published
    Cell-Free DNA and Clinical Characteristics in Patients with Small Intestinal or Pancreatic Neuroendocrine Tumors. / Oversø, Stine Karlsen; Sørensen, Boe Sandahl; Tabaksblat, Elizaveta Mitkina et al.
    In: Neuroendocrinology, Vol. 112, No. 1, 01.2022, p. 43-50.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  18. Published
    STAT3 is over-activated within CD163pos bone marrow macrophages in both Multiple Myeloma and the benign pre-condition MGUS. / Andersen, Morten N; Andersen, Niels F; Lauridsen, Kristina L et al.
    In: Cancer Immunology, Immunotherapy, Vol. 71, No. 1, 01.2022, p. 177-187.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  19. 2021
  20. Published
    Alectinib-Induced Pleural and Pericardial Effusions in ALK-Positive NSCLC. / Ulhoi, Maiken Parm; Sorensen, Boe Sandahl; Meldgaard, Peter.
    In: Case Reports in Oncology, Vol. 14, No. 14, 11.2021, p. 1323-1327.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  21. Published
    Co-occurring MET Amplification Predicts Inferior Clinical Response to First-Line Erlotinib in Advanced Stage EGFR-Mutated NSCLC Patients. / Clement, Michelle S.; Ebert, Eva Boysen Fynboe; Meldgaard, Peter et al.
    In: Clinical Lung Cancer, Vol. 22, No. 6, 11.2021, p. e870-e877.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  22. Published
    EGFR transcription in non-small-cell lung cancer tumours can be revealed in ctDNA by cell-free chromatin immunoprecipitation (cfChIP). / Månsson, Christoffer Trier; Vad-Nielsen, Johan; Meldgaard, Peter et al.
    In: Molecular Oncology, Vol. 15, No. 11, 11.2021, p. 2868-2876.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  23. Published
    Soluble PD-1 (sPD-1) is expressed in human macrophages. / Antonsen, Kristian W; Hviid, Claus V B; Hagensen, Mette K et al.
    In: Cellular Immunology, Vol. 369, 104435, 11.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  24. Published
    Targeted next generation sequencing panel for HPV genotyping in cervical cancer. / Lippert, J.; Bønløkke, S.; Utke, A. et al.
    In: Experimental and Molecular Pathology, Vol. 118, 104568, 02.2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  25. Published
    cGAS-STING pathway expression as a prognostic tool in NSCLC. / Raaby Gammelgaard, Kristine; Sandfeld-Paulsen, Birgitte; Godsk, Stine Høvring et al.
    In: Translational Lung Cancer Research, Vol. 10, No. 1, 01.2021, p. 340-354.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  26. Published
    Combining tissue and circulating tumor DNA increases the detection rate of a CTNNB1 mutation in hepatocellular carcinoma. / Oversoe, Stine Karlsen; Clement, Michelle Simone; Weber, Britta et al.
    In: BMC Cancer, Vol. 21, No. 1, 376, 2021.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  27. 2020
  28. Published
    TERT promoter mutated circulating tumor DNA as a biomarker for prognosis in hepatocellular carcinoma. / Oversoe, Stine K; Clement, Michelle S; Pedersen, Michael H et al.
    In: Scandinavian Journal of Gastroenterology, Vol. 55, No. 12, 12.2020, p. 1433-1440.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  29. Published
    Epithelial-to-mesenchymal transition is a resistance mechanism to sequential MET-TKI treatment of MET-amplified EGFR-TKI resistant non-small cell lung cancer cells. / Clement, Michelle Simone; Gammelgaard, Kristine Raaby; Nielsen, Anders Lade et al.
    In: Translational Lung Cancer Research, Vol. 9, No. 5, 10.2020, p. 1904-1914.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  30. Published
    Neurofilament light chain as a biomarker for brain metastases. / Winther‐Larsen, Anne; Hviid, Claus Vinter Bødker; Meldgaard, Peter et al.
    In: Cancers, Vol. 12, No. 10, 2852, 10.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  31. Published
    Cell-free Chromatin Immunoprecipitation (cfChIP) from blood plasma can determine gene-expression in tumors from non-small-cell lung cancer patients. / Vad-Nielsen, Johan; Meldgaard, Peter; Sorensen, Boe Sandahl et al.
    In: Lung Cancer, Vol. 147, 09.2020, p. 244-251.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  32. Published
    Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid. / Kirkegaard, Kirstine; Yan, Yan; Sørensen, Boe S. et al.
    In: Journal of Assisted Reproduction and Genetics, Vol. 37, No. 9, 09.2020, p. 2199–2209.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  33. Published
    Inflammatory Cytokines and ctDNA Are Biomarkers for Progression in Advanced-Stage Melanoma Patients Receiving Checkpoint Inhibitors. / Pedersen, Jesper Geert; Madsen, Anne Tranberg; Gammelgaard, Kristine Raaby et al.
    In: Cancers, Vol. 12, No. 6, 1414, 06.2020, p. 1-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  34. Published
    Clearing of circulating tumour DNA predicts clinical response to first line tyrosine kinase inhibitors in advanced epidermal growth factor receptor mutated non-small cell lung cancer. / Ebert, Eva Boysen Fynboe; McCulloch, Tine; Holmskov, Karin et al.
    In: Lung Cancer, Vol. 141, 03.2020, p. 37-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  35. Published
    Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy: A Randomized Controlled Trial (SUPER). / Skougaard, Kristin; Østrup, Olga; Guldbrandsen, Kasper et al.
    In: Clinical Lung Cancer, Vol. 21, No. 2, 03.2020, p. e61-e64.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  36. Published
    Clearing of circulating tumour DNA predicts clinical response to osimertinib in EGFR mutated lung cancer patients. / Boysen Fynboe Ebert, Eva; McCulloch, Tine; Holmskov Hansen, Karin et al.
    In: Lung Cancer, Vol. 143, 2020, p. 67-72.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  37. Published
    Genomic profiling of circulating tumor DNA predicts outcome and demonstrates tumor evolution in ALK-positive non-small cell lung cancer patients. / Madsen, Anne Tranberg; Winther-Larsen, Anne; McCulloch, Tine et al.
    In: Cancers, Vol. 12, No. 4, 947, 2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  38. Published
    HPV DNA in the blood of cervical cancer patients - clinical implications. / Simonsen, Sara Bønløkke; Blaakær, Jan; Sørensen, Boe Sandahl et al.
    2020. Abstract from Eurogin 2019, Monaco.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  39. 2019
  40. Published
    Intra-individual variation of circulating tumour DNA in lung cancer patients. / Hojbjerg, Johanne A; Madsen, Anne T; Schmidt, Hjordis H et al.
    In: Molecular Oncology, Vol. 13, No. 10, 10.2019, p. 2098-2106.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  41. Published
    Circulating miR-30b and miR-30c predict erlotinib response in EGFR-mutated non-small cell lung cancer patients. / Hojbjerg, Johanne Andersen; Ebert, Eva Boysen Fynboe; Clement, Michelle Simone et al.
    In: Lung Cancer, Vol. 135, 09.2019, p. 92-96.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  42. Published
    Correlation between early dynamics in circulating tumour DNA and outcome from FOLFIRI treatment in metastatic colorectal cancer. / Lyskjær, Iben; Kronborg, Camilla Skovhus; Rasmussen, Mads Heilskov et al.
    In: Scientific Reports, Vol. 9, No. 1, 11542, 08.08.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  43. Published
    The prognostic role of inflammation-scores on overall survival in lung cancer patients. / Paulsen, Birgitte Sandfeld; Meldgaard, Peter; Sørensen, Boe Sandahl et al.
    In: Acta Oncologica, Vol. 58, No. 3, 03.2019, p. 371-376.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  44. Published
    Day-to-day and within-day biological variation of cell-free DNA. / Madsen, Anne Tranberg; Hojbjerg, Johanne Andersen; Sorensen, Boe Sandahl et al.
    In: EBioMedicine, Vol. 49, 2019, p. 284-290.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  45. Published
    EGFR Gene Polymorphism Predicts Improved Outcome in Patients With EGFR Mutation-positive Non–small cell Lung Cancer Treated With Erlotinib. / Winther-Larsen, Anne; Fynboe Ebert, Eva Boysen; Meldgaard, Peter et al.
    In: Clinical Lung Cancer, Vol. 20, No. 3, 2019, p. 161-166.e1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  46. Published
    Up-Regulated FGFR1 Expression as a Mediator of Intrinsic TKI Resistance in EGFR-Mutated NSCLC. / Gammelgaard, Kristine Raaby; Vad-Nielsen, Johan; Clement, Michelle Simone et al.
    In: Translational Oncology, Vol. 12, No. 3, 2019, p. 432-440.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  47. 2018
  48. Published
    Methodological development and biological observations of cell free DNA with a simple direct fluorescent assay in colorectal cancer. / Boysen, A K; Sorensen, B S; Lefevre, A C et al.
    In: Clinica chimica acta; international journal of clinical chemistry, Vol. 487, 12.2018, p. 107-111.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  49. Published
    Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer. / Spindler, Karen-Lise Garm; Demuth, Christina; Sorensen, Boe Sandahl et al.
    In: Tumor Biology, Vol. 40, No. 11, 11.2018, p. 1-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  50. Published
    Measuring KRAS Mutations in Circulating Tumor DNA by Droplet Digital PCR and Next-Generation Sequencing. / Demuth, Christina; Spindler, Karen-Lise Garm; Johansen, Julia S. et al.
    In: Translational Oncology, Vol. 11, No. 5, 10.2018, p. 1220-1224.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  51. Published
    CIRCULATING TUMOR DNA - DETECTION OF CTNNB1 MUTATIONS IN PLASMA FROM A DANISH COHORT OF HCC PATIENTS. / Karlsen, Stine; Clement, Michelle Simone; Weber, Britta et al.
    2018. 44-45 Abstract from International Liver Cancer Association Annual Conference, London, United Kingdom.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  52. Published
    A method for treatment monitoring using circulating tumour DNA in cancer patients without targetable mutations. / Demuth, Christina; Winther-Larsen, Anne; Madsen, Anne Tranberg et al.
    In: OncoTarget, Vol. 9, No. 57, 24.07.2018, p. 31066-31076.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  53. Published
    Detection of EGFR Variants in Plasma: A Multilaboratory Comparison of a Real-Time PCR EGFR Mutation Test in Europe. / Keppens, Cleo; Palma, John F; Das, Partha M et al.
    In: The Journal of molecular diagnostics : JMD, Vol. 20, No. 4, 07.2018, p. 483-494.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  54. Published
    The T790M resistance mutation in EGFR is only found in cfDNA from erlotinib-treated NSCLC patients that harbored an activating EGFR mutation before treatment. / Demuth, Christina; Madsen, Anne Tranberg; Weber, Britta et al.
    In: BMC Cancer, Vol. 18, No. 1, 191, 15.02.2018, p. 191.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  55. Published
    Soluble HER3 predicts survival in bladder cancer patients. / Memon, Ashfaque A; Gilliver, Stephen C; Borre, Michael et al.
    In: Oncology Letters, Vol. 15, No. 2, 02.2018, p. 1783-1788.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  56. Published
    STING regulation in lung cancer. / Gammelgaard, Kristine Raaby; Paulsen, Birgitte Sandfeld; Demuth, Christina et al.
    2018. Poster session presented at Dansk Selskab for Cancerforskning Årsmøde.

    Research output: Contribution to conference › Poster › Research

  57. Published
    The Impact of genetic Variants of STING and IFI16 on Non-Small Cell Lung Cancer. / Gammelgaard, Kristine Raaby; Paulsen, Birgitte Sandfeld; Demuth, Christina et al.
    2018. Poster session presented at HOST-PATHOGEN COMMUNICATION MEETING 2018, Rehovot, Israel.

    Research output: Contribution to conference › Poster › Research › peer-review

  58. 2017
  59. Published
    Cell-free DNA levels and correlation to stage and outcome following treatment of locally advanced rectal cancer. / Boysen, Anders Kindberg; Wettergren, Yvonne; Sorensen, Boe Sandahl et al.
    In: Tumor Biology, Vol. 39, No. 11, 07.11.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  60. Published
    Applicability of Ion Torrent Colon and Lung sequencing panel on circulating cell-free DNA. / Demuth, Christina; Tranberg Madsen, Anne; Larsen, Anne Winther et al.
    2017. Abstract from IASLC 18th World Conference on Lung Cancer, Tokyo, Japan.

    Research output: Contribution to conference › Conference abstract for conference › Research

  61. Published
    Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment. / Demuth, Christina; Andersen, Morten Nørgaard; Jakobsen, Kristine Raaby et al.
    In: OncoTarget, Vol. 8, No. 40, 15.09.2017, p. 68221-68229.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  62. Published
    Correlation between circulating mutant DNA and metabolic tumour burden in advanced non-small cell lung cancer patients. / Winther-Larsen, Anne; Demuth, Christina; Fledelius, Joan et al.
    In: B J C, Vol. 117, No. 5, 22.08.2017, p. 704-709.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  63. Published
    Post-cardiac arrest level of free-plasma DNA and DNA-histone complexes. / Jeppesen, A N; Hvas, A-M; Grejs, A M et al.
    In: Acta Anaesthesiologica Scandinavica, Vol. 61, No. 5, 05.2017, p. 523-531.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  64. Published
    MET amplification and epithelial-to-mesenchymal transition exist as parallel resistance mechanisms in erlotinib-resistant, EGFR-mutated, NSCLC HCC827 cells. / Jakobsen, K R; Demuth, C; Tranberg Madsen, Anne et al.
    In: Oncogenesis, Vol. 6, No. 4, e307, 03.04.2017, p. e307.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  65. Published
    IGF1R depletion facilitates MET-amplification as mechanism of acquired resistance to erlotinib in HCC827 NSCLC cells. / Hussmann, Dianna; Madsen, Anne Tranberg; Jakobsen, Kristine Raaby et al.
    In: OncoTarget, Vol. 8, No. 20, 18.03.2017, p. 33300-33315.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  66. Published
    Mechanisms of Acquired Resistance to the ALK Inhibitor Lorlatinib in ALK-Rearranged NSCLC Cell Lines. / Tranberg Madsen, Anne; Jakobsen, Kristine Raaby; Demuth, Christina et al.
    2017. S2255 Abstract from IASLC 18th World Conference on Lung Cancer, Tokyo, Japan.

    Research output: Contribution to conference › Conference abstract for conference › Research

  67. 2016
  68. Published
    Early Change in FDG-PET Signal and Plasma Cell-Free DNA Level Predicts Erlotinib Response in EGFR Wild-Type NSCLC Patients. / Winther-Larsen, Anne; Fledelius, Joan; Demuth, Christina et al.
    In: Translational Oncology, Vol. 9, No. 6, 12.2016, p. 505-511.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  69. Published
    Exosomal proteins as prognostic biomarkers in non-small cell lung cancer. / Paulsen, Birgitte Sandfeld; Aggerholm-Pedersen, N; Bæk, R et al.
    In: Molecular Oncology, Vol. 10, No. 10, 12.2016, p. 1595-1602.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  70. Published
    Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer. / Sandfeld-Paulsen, Birgitte; Jakobsen, Kristine Raaby; Bæk, Rikke et al.
    In: Journal of Thoracic Oncology, Vol. 11, No. 10, 10.2016, p. 1701-10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  71. Published
    Increase in soluble PD-1 is associated with prolonged survival in patients with advanced EGFR-mutated non-small cell lung cancer treated with erlotinib. / Sorensen, Steffen Filskov; Demuth, Christina; Weber, Britta et al.
    In: Lung Cancer, Vol. 100, 10.2016, p. 77-84.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  72. Published
    Gene Expression of the EGF System-a Prognostic Model in Non-Small Cell Lung Cancer Patients Without Activating EGFR Mutations. / Sandfeld-Paulsen, Birgitte; Folkersen, Birgitte Holst; Rasmussen, Torben Riis et al.
    In: Translational Oncology, Vol. 9, No. 4, 08.2016, p. 306-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  73. Published
    Metabolic tumor burden as marker of outcome in advanced EGFR wild-type NSCLC patients treated with erlotinib. / Winther-Larsen, Anne; Fledelius, Joan; Sorensen, Boe Sandahl et al.
    In: Lung Cancer, Vol. 94, 04.2016, p. 81-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  74. Published
    The role of epithelial to mesenchymal transition in resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. / Jakobsen, Kristine Raaby; Demuth, Christina; Sorensen, Boe Sandahl et al.
    In: Translational Lung Cancer Research, Vol. 5, No. 2, 04.2016, p. 172-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  75. Published
    Ultra-micro samples can be used for mRNA quantification of lung cancer biomarkers. / Sandfeld-Paulsen, Birgitte; Demuth, Christina; Folkersen, Birgitte H et al.
    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 76, No. 3, 29.02.2016, p. 243-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  76. Published
    Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy. / Aggerholm-Pedersen, Ninna; Demuth, Christina; Safwat, Akmal et al.
    In: Stem Cells and Development, Vol. 2016, 9601493, 2016, p. 9601493.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  77. Published
    Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells. / Vad-Nielsen, Johan; Jakobsen, Kristine Raaby; Daugaard, Tina Fuglsang et al.
    In: B M C Cancer, Vol. 16, No. 1, 32, 2016, p. 32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  78. 2015
  79. Published
    Genetic polymorphism in the epidermal growth factor receptor gene predicts outcome in advanced non-small cell lung cancer patients treated with erlotinib. / Winther-Larsen, Anne; Nissen, Peter H.; Jakobsen, Kristine Raaby et al.
    In: Lung Cancer, Vol. 90, No. 2, 11.2015, p. 314-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  80. Published
    PD-L1 expression is induced by MET in an erlotinib-resistant cell line with MET amplification. / Demuth, Christina; Andersen, Morten Nørgaard; Tranberg Madsen, Anne et al.
    2015. Abstract from 16th World Conference on Lung Cancer , Denver, Colorado, United States.

    Research output: Contribution to conference › Conference abstract for conference › Research

  81. Published
    Exosomal proteins as diagnostic biomarkers in advanced lung adenocarcinoma. / Jakobsen, Kristine Raaby; Paulsen, Birgitte Sandfeld; Bæk, Rikke et al.
    2015. Abstract from the Fourth International Meeting of ISEV, Washington DC, United States.

    Research output: Contribution to conference › Conference abstract for conference › Research

  82. Published
    Different receptor tyrosine kinases mediate EMT and erlotinib-resistance in NSCLC cell lines through bypass signalling. / Jakobsen, Kristine Raaby; Demuth, Christina; Tranberg Madsen, Anne et al.
    2015. Abstract from AACR annual meeting 2015, Philadelphia, United States.

    Research output: Contribution to conference › Conference abstract for conference › Research

  83. Published
    EGFR and HER3 are important in the interaction between lung cancer cells and fibroblasts. / Demuth, Christina; Jakobsen, Kristine Raaby; Meldgaard, Peter et al.
    2015. Abstract from AACR annual meeting 2015, Philadelphia, PA, United States.

    Research output: Contribution to conference › Conference abstract for conference › Research

  84. Published
    Exosomal proteins as potential diagnostic markers in advanced non-small cell lung carcinoma. / Jakobsen, Kristine Raaby; Paulsen, Birgitte Sandfeld; Bæk, Rikke et al.
    In: Journal of Extracellular Vesicles, Vol. 4, 03.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  85. Published
    Co-expression of HER3 and MUC1 is associated with a favourable prognosis in patients with bladder cancer. / Nielsen, Trine O; Borre, Michael; Nexo, Ebba et al.
    In: B J U International (Print), Vol. 115, No. 1, 01.2015, p. 163-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  86. 2014
  87. Published
    Monitoring of epidermal growth factor receptor tyrosine kinase inhibitor-sensitizing and resistance mutations in the plasma DNA of patients with advanced non-small cell lung cancer during treatment with erlotinib. / Sorensen, Boe S; Wu, Lin; Wei, Wen et al.
    In: Cancer, Vol. 120, No. 24, 15.12.2014, p. 3896-901.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  88. Published
    EGFR CA repeat polymorphism predict clinical outcome in EGFR mutation positive NSCLC patients treated with erlotinib. / Winther Larsen, Anne; Nissen, Peter Henrik; Meldgaard, Peter et al.
    In: Lung Cancer, Vol. 85, No. 3, 09.2014, p. 435-41.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  89. Published
    Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays. / Weber, Britta; Meldgaard, Peter; Hager, Henrik et al.
    In: B M C Cancer, Vol. 14, 28.04.2014, p. 294.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  90. Published
    Expression of the EGF family in gastric cancer: downregulation of HER4 and its activating ligand NRG4. / Nielsen, Trine Ostergaard; Friis-Hansen, Lennart; Poulsen, Steen Seier et al.
    In: PLOS ONE, Vol. 9, No. 4, 11.04.2014, p. e94606.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  91. Published
    EGFR mutation frequency and effectiveness of erlotinib: A prospective observational study in danish patients with non-small cell lung cancer. / Weber, B.; Hager, H.; Sørensen, B.S. et al.
    In: Lung Cancer, Vol. 83, No. 2, 01.02.2014, p. 224-230.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  92. Published
    Expression of the epidermal growth factor system in human middle ear cholesteatoma. / Thorup, Mette Bendixen; Munk, Mathias; Poulsen, Steen Seier et al.
    In: Acta Oto-Laryngologica, Vol. 134, No. 2, 21.01.2014, p. 124-134.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  93. 2013
  94. Published
    Expression of PIK3CA, PTEN mRNA and PIK3CA mutations in primary breast cancer: association with lymph node metastases. / Palimaru, Irina; Brügmann, Anja; Wium-Andersen, Marie Kim et al.
    In: SpringerPlus, Vol. 2, 16.09.2013, p. 464.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  95. Published
    The HER4 isoform JM-a/CYT2 relates to improved survival in bladder cancer patients but only if the estrogen receptor α is not expressed. / Munk, Mathias; Memon, Ashfaque; Poulsen, Steen S et al.
    In: Scandinavian journal of clinical and laboratory investigation, Vol. 73, No. 6, 09.2013, p. 503-13.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  96. Published
    Directing HER4 mRNA expression towards the CYT2 isoform by antisense oligonucleotide decreases growth of breast cancer cells in vitro and in vivo. / Nielsen, Trine O; Sorensen, Suzette; Dagnæs-Hansen, Frederik et al.
    In: B J C, Vol. 108, No. 11, 11.06.2013, p. 2291-2298.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  97. 2012
  98. Published
    A Single Rainbow Trout Cobalamin-Binding Protein Stands in for Three Human Binders. / Greibe, Eva Holm; Fedosov, Sergey; Sørensen, Boe Sandahl et al.
    In: Journal of Biological Chemistry, Vol. 287, No. 40, 01.2012, p. 33917-33925.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  99. Published
    Composition useful as a medicament for treating cancer and/or neuropsychiatric disorders, comprises a binding member capable of binding to a human epidermal growth factor (EGF) receptor 4 (HER4) polypeptide and/or a HER4 RNA. / Østergaard, Trine (Inventor); Sørensen, Boe Sandahl (Inventor); Sørensen, Suzette (Inventor) et al.
    Patent No.: WO2011107100-A1 .

    Research output: Patent

  100. Published
    Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes. / Munk, Mathias; Memon, Ashfaque Ahmed; Goetze, Jens Peter et al.
    In: P L o S One, Vol. 7, No. 7, 2012, p. e40243.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  101. 2011
  102. Published
    Complete Pathologic Response in Lung Tumors in Two Patients with Metastatic Non-small Cell Lung Cancer Treated with Erlotinib. / Weber, Britta; Sørensen, Boe Sandahl; Knap, Marianne Marquard et al.
    In: Journal of Thoracic Oncology, Vol. 6, No. 11, 01.11.2011, p. 1946-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  103. Published
    Erlotinib Accumulation in Brain Metastases from Non-small Cell Lung Cancer: Visualization by Positron Emission Tomography in a Patient Harboring a Mutation in the Epidermal Growth Factor Receptor. / Weber, Britta; Winterdahl, Michael; Memon, Ashfaque et al.
    In: Journal of Thoracic Oncology, Vol. 6, No. 7, 01.07.2011, p. 1287-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  104. Published
    Identifying responders to trastuzumab therapy in breast cancer. / Brügmann, Anja; Sørensen, Boe Sandahl.
    In: Future Oncology, Vol. 7, No. 6, 01.06.2011, p. 767-73.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

  105. Published
    Mouse Transcobalamin Has Features Resembling both Human Transcobalamin and Haptocorrin. / Hygum, Katrine; Lildballe, Dorte L; Greibe, Eva H et al.
    In: P L o S One, Vol. 6, No. 5, 31.05.2011, p. e20638.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  106. Published
    Calcium-induced apoptosis is delayed by HER1 receptor signalling through the Akt and PLCγ pathways in bladder cancer cells. / Memon, Ashfaque A; Munk, Mathias; Nexø, Ebba et al.
    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 71, No. 1, 01.02.2011, p. 45-51.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  107. Published
    HER4 Is Downregulated in Lymph node Metastases Compared to the Paired Primary Breast Carcinoma. / Brügmann, Anja Høegh; Jensen, Vibeke Eleonora Dagmar; Garne, Jens Peter et al.
    2011. Abstract from PhD day 2011, Aarhus, Denmark.

    Research output: Contribution to conference › Conference abstract for conference › Research

  108. Published
    PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer. / Memon, A A; Weber, B; Winterdahl, M et al.
    In: B J C, Vol. 105, No. 12, 2011, p. 1850-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  109. 2010
  110. Published
    HER4 is downregulated in lymph node metastases compared to the paired primary breast carcinoma. / Brügmann, Anja Høegh; Jensen, Vibeke Eleonora Dagmar; Garne, Jens Peter et al.
    2010. Abstract from 33RD Annual San Antonio Breast Cancer Symposium .

    Research output: Contribution to conference › Conference abstract for conference › Research

  111. Published
    Circulating HER2 DNA after trastuzumab treatment predicts survival and response in breast cancer. / Sorensen, Boe S; Mortensen, Lise S; Andersen, Jørn et al.
    In: Anticancer Research, Vol. 30, No. 6, 2010, p. 2463-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

  112. Published
    HER4 is downregulated in lymphnode metastases compared to the primary breast carcinoma. / Brügmann, Anja Høegh; Jensen, Vibeke Eleonora Dagmar; Garne, Jens Peter et al.
    2010. Abstract from Forskningens Dag 2010 - Aalborg Sygehus, Aalborg.

    Research output: Contribution to conference › Conference abstract for conference › Research

  113. 2009
  114. Published
    [11C] labeled erlotinib as a new radiotracer for identification of patients responding to erlotinib treatment: A preliminary study on lung cancer patients. / Memon, Ashfaque Ahmed; Weber, Britta; Jakobsen, Steen et al.
    In: Journal of Thoracic Oncology, No. 9, 2009, p. S698.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research

  115. Published
    Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant. / Frogne, Thomas; Benjaminsen, Rikke V.; Sonne Hansen, Katrine et al.
    In: Breast Cancer Research and Treatment, Vol. 114, 2009, p. 263-75.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

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