Department of Economics and Business Economics

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Bjarni Jóhann Vilhjálmsson

Professor

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Bjarni Jóhann Vilhjálmsson

Professor

  • National Centre for Register-based Research
  • National Centre for Register-based Research
Postal address:
Fuglesangs Allé 26
2641, 228
8210
Aarhus V
Denmark

Email: bjv@au.dk

Curriculum Vitae

CV (pdf)

Employment

Professor

National Centre for Register-based Research

Aarhus University

Aarhus V, Denmark

1 Nov 2020 → present

Senior Researcher

Department of Economics and Business Economics

Aarhus University

Aarhus V, Denmark

13 Sept 2018 → 1 Nov 2020

Postdoc

Bioinformatics Research Centre (BiRC)

Aarhus University

Aarhus C, Denmark

14 Apr 2014 → 21 Sept 2017

Postdoc

Bioinformatics Research Centre (BiRC)

Aarhus University

Aarhus C, Denmark

11 Apr 2014 → 14 Apr 2014

Postdoc

Bioinformatics Research Centre (BiRC)

Aarhus University

Aarhus C, Denmark

24 Jan 2014 → 11 Apr 2014

Research outputs

Polygenic Risk and Episode Polarity Among Individuals With Bipolar Disorder

Hasseris, S., Albiñana, C., Vilhjalmsson, B. J., Mortensen, P. B., Østergaard, S. D. & Musliner, K. L., Mar 2023, In: American Journal of Psychiatry. 180, 3, p. 200-208 9 p.

Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots

Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & McGrath, J. J., 15 Feb 2023, In: Nature Communications. 14, 1, p. 852

Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study

Brikell, I., Wimberley, T., Albiñana, C., Vilhjálmsson, B. J., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, T., Hougaard, D. M., Nordentoft, M., Mors, O., Mortensen, P. B., Petersen, L. V. & Dalsgaard, S., Jan 2023, In: The American Journal of Psychiatry (Spanish Edition). 180, 1, p. 73-88 16 p.

Polygenic liability, stressful life events and risk for secondary-treated depression in early life: a nationwide register-based case-cohort study

Musliner, K. L., Andersen, K. K., Agerbo, E., Albiñana, C., Vilhjalmsson, B. J., Rajagopal, V. M., Bybjerg-Grauholm, J., Bækved-Hansen, M., Pedersen, C. B., Pedersen, M. G., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., Suppli, N. P. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2023, In: Psychological Medicine. 53, 1, p. 217-226 10 p.

Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders

Debost, J-C. P. G., Thorsteinsson, E., Trabjerg, B., Benros, M. E., Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, T., Mortensen, P. B., Agerbo, E. & Petersen, L., Nov 2022, In: Acta Psychiatrica Scandinavica. 146, 5, p. 406-419 14 p.

Harnessing the Power of Population Cohorts to Study the Relationship Between Endocrine-Metabolic Disorders and Depression

Jespersen, A., Yilmaz, Z. & Vilhjálmsson, B. J., Nov 2022, In: The American Journal of Psychiatry (Spanish Edition). 179, 11, p. 788-790 3 p.

Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

Privé, F., Arbel, J., Aschard, H. & Vilhjálmsson, B. J., Oct 2022, In: Human Genetics and Genomics Advances. 3, 4, 100136.

Developmental exposure to vitamin D deficiency and subsequent risk of schizophrenia

Albiñana, C., Boelt, S. G., Cohen, A. S., Zhu, Z., Musliner, K. L., Vilhjálmsson, B. J. & McGrath, J. J., Sept 2022, In: Schizophrenia Research. 247, p. 26-32 7 p.

Genetic liability to posttraumatic stress disorder and its association with postpartum depression

Bang Madsen, K., Liu, X., Albiñana, C., Jóhann Vilhjálmsson, B., Agerbo, E., Mortensen, P. B., Hougaard, D. M., Nordentoft, M., Werge, T., Mors, O., Børglum, A. D. & Munk-Olsen, T., 11 Jul 2022, (E-pub ahead of print) In: Psychological Medicine. p. 1-8 8 p.

A method to correct for the influence of bovine serum albumin-associated vitamin D metabolites in protein extracts from neonatal dried blood spots

Boelt, S. G., Plana-Ripoll, O., Albiñana, C., Vilhjálmsson, B., McGrath, J. J. & Cohen, A. S., 3 Jun 2022, In: BMC Research Notes. 15, 1, p. 194 7 p., 194.

Accounting for age of onset and family history improves power in genome-wide association studies

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Privé, F. & Vilhjálmsson, B. J., Mar 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.

Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R., Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, H., Pers, T. H., Mortensen, P. B., Mors, O., Nordentoft, M., Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, A., Melbye, M., Ullum, H., Berkovic, S. F., Werge, T. & Feenstra, B., Feb 2022, In: Brain : a journal of neurology. 145, 2, p. 555–568

Early-Life Injuries and the Development of Attention-Deficit/Hyperactivity Disorder

Wimberley, T., Brikell, I., Pedersen, E. M., Agerbo, E., Vilhjálmsson, B. J., Albiñana, C., Privé, F., Thapar, A., Langley, K., Riglin, L., Simonsen, M., Nielsen, H. S., Børglum, A. D., Nordentoft, M., Mortensen, P. B. & Dalsgaard, S., Jan 2022, In: Journal of Clinical Psychiatry. 83, 1, 14 p.

Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism

Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Børglum, A. D., Werge, T., Nordentoft, M., Mortensen, P. B. & Agerbo, E., Jan 2022, In: Autism Research. 15, 1, p. 171-182 12 p.

Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification

Ding, Y., Hou, K., Burch, K. S., Lapinska, S., Privé, F., Vilhjálmsson, B., Sankararaman, S. & Pasaniuc, B., Jan 2022, In: Nature Genetics. 54, 1, p. 30–39 10 p.

Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort

Privé, F., Aschard, H., Carmi, S., Folkersen, L., Hoggart, C., O'Reilly, P. F. & Vilhjálmsson, B. J., Jan 2022, In: American Journal of Human Genetics. 109, 1, p. 12-23 12 p.

Improved genetic prediction of complex traits from individual-level data or summary statistics

Zhang, Q., Privé, F., Vilhjálmsson, B. & Speed, D., Dec 2021, In: Nature Communications. 12, 1, 9 p., 4192.

Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD

Brikell, I., Wimberley, T., Albiñana, C., Pedersen, E. M., Vilhjálmsson, B. J., Agerbo, E., Demontis, D., Børglum, A. D., Schork, A. J., LaBianca, S., Werge, T., Mors, O., Hougaard, D. M., Thapar, A., Mortensen, P. B. & Dalsgaard, S., Sept 2021, In: American Journal of Psychiatry. 178, 9, p. 854-864 11 p.

Multitrait GWAS to connect disease variants and biological mechanisms

Julienne, H., Laville, V., McCaw, Z. R., He, Z., Guillemot, V., Lasry, C., Ziyatdinov, A., Nerin, C., Vaysse, A., Lechat, P., Ménager, H., Le Goff, W., Dube, M-P., Kraft, P., Ionita-Laza, I., Vilhjálmsson, B. J. & Aschard, H., Aug 2021, In: PLOS Genetics. 17, 8, 36 p., e1009713.

Polygenic Liability and Recurrence of Depression in Patients With First-Onset Depression Treated in Hospital-Based Settings

Musliner, K. L., Agerbo, E., Vilhjálmsson, B. J., Albiñana, C., Als, T. D., Østergaard, S. D. & Mortensen, P. B., Jul 2021, In: JAMA Psychiatry. 78, 7, p. 792-795

Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, M., Hougaard, D. M., Werge, T., Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., Jun 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 10 p.

Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain

Christiansen, M. K., Winther, S., Nissen, L., Vilhjálmsson, B. J., Frost, L., Johansen, J. K., Loof Møller, P., Schmidt, S. E., Westra, J. S., Holm, N. R., Jensen, H. K., Christiansen, E. H., Guðbjartsson, D. F., Hólm, H., Stefansson, K., Bøtker, H. E., Bøttcher, M. & Nyegaard, M., Jun 2021, In: Circulation. Genomic and precision medicine. 14, 3, p. 323-330 8 p., 003298.

Finding hidden treasures in summary statistics from genome-wide association studies

Privé, F., Zhu, Z. & Vilhjalmsson, B. J., Apr 2021, In: Nature Genetics. 53, 4, p. 431-432

Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status

Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, T., Wray, N. R., Mortensen, P. B. & Musliner, K. L., Apr 2021, In: JAMA Psychiatry. 78, 4, p. 387-397 11 p.

LDpred2: better, faster, stronger

Privé, F., Arbel, J. & Vilhjálmsson, B. J., Dec 2020, In: Bioinformatics. 36, 22-23, p. 5424-5431 8 p.

Linking the association between circRNAs and Alzheimer's disease progression by multi-tissue circular RNA characterization

Lo, IJ., Hill, J., Vilhjálmsson, B. J. & Kjems, J., Dec 2020, In: RNA Biology. 17, 12, p. 1789-1797 9 p.

Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia

Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, M., Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, T., Svenning, J-C. & Horsdal, H. T., Nov 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.

Genetic liability to major depression and risk of childhood asthma

Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B. & Agerbo, E., Oct 2020, In: Brain, Behavior, and Immunity. 89, p. 433-439 7 p.

Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population-based cohort study

Plana-Ripoll, O., Musliner, K. L., Dalsgaard, S., Momen, N. C., Weye, N., Christensen, M. K., Agerbo, E., Iburg, K. M., Laursen, T. M., Mortensen, P. B., Pedersen, C. B., Petersen, L. V., Santomauro, D. F., Vilhjálmsson, B. J., Whiteford, H. A. & McGrath, J. J., Oct 2020, In: World Psychiatry. 19, 3, p. 339-349 11 p.

Polygenic Risk and Progression to Bipolar or Psychotic Disorders Among Individuals Diagnosed With Unipolar Depression in Early Life

Musliner, K. L., Krebs, M. D., Albiñana, C., Vilhjalmsson, B., Agerbo, E., Zandi, P. P., Hougaard, D. M., Nordentoft, M., Børglum, A. D., Werge, T., Mortensen, P. B. & Østergaard, S. D., Oct 2020, In: The American Journal of Psychiatry. 177, 10, p. 936-943

Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder

Østergaard, S. D., Trabjerg, B. B., Als, T. D., Albiñana, C., Privé, F., Vilhjálmsson, B. J., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, M., Werge, T., Demontis, D., Mortensen, P. B., Børglum, A. D., Mors, O. & Agerbo, E., Oct 2020, In: Translational Psychiatry. 10, 1, 11 p., 335.

Families, Health Registers, and Biobanks: Making the Unmeasurable Measurable

Albiñana, C., Vilhjálmsson, B. J. & McGrath, J. J., Sept 2020, In: Biological Psychiatry. 88, 6, p. 440-441 2 p.

Efficient toolkit implementing best practices for principal component analysis of population genetic data

Privé, F., Luu, K., Blum, M. G. B., McGrath, J. J. & Vilhjálmsson, B. J., Aug 2020, In: Bioinformatics (Online). 36, 16

Symbiosis genes show a unique pattern of introgression and selection within a Rhizobium leguminosarum species complex

Cavassim, M. I. A., Moeskjær, S., Moslemi, C., Fields, B., Bachmann, A., Vilhjálmsson, B. J., Schierup, M. H., W Young, J. P. & Andersen, S. U., Apr 2020, In: Microbial Genomics. 6, 4

JASS: command line and web interface for the joint analysis of GWAS results

Julienne, H., Lechat, P., Guillemot, V., Lasry, C., Yao, C., Araud, R., Laville, V., Vilhjalmsson, B., Ménager, H. & Aschard, H., Mar 2020, In: NAR genomics and bioinformatics. 2, 1, 12 p., lqaa003.

Association between Mental Disorders and Subsequent Medical Conditions

Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E., Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P., Debost, J. C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C., Laursen, T. M., Lim, C. C. W., Mors, O., Mortensen, P. B., Musliner, K. L., Nordentoft, M., Pedersen, C. B., Petersen, L. V., Ribe, A. R., Roest, A. M., Saha, S., Schork, A. J., Scott, K. M., Sievert, C., Sørensen, H. J., Vestergaard, M., Stedman, T. J., Vilhjalmsson, B., Werge, T., Weye, N., Whiteford, H. A., Prior, A. & McGrath, J. J., 2020, In: The New England Journal of Medicine. 382, 18, p. 1721-1731 11 p.

Extreme genetic signatures of local adaptation during Lotus japonicus colonization of Japan

Shah, N., Wakabayashi, T., Kawamura, Y., Skovbjerg, C. K., Wang, M-Z., Mustamin, Y., Isomura, Y., Gupta, V., Jin, H., Mun, T., Sandal, N., Azuma, F., Fukai, E., Seren, Ü., Kusakabe, S., Kikuchi, Y., Nitanda, S., Kumaki, T., Hashiguchi, M., Tanaka, H., Hayashi, A., Sønderkær, M., Nielsen, K. L., Schneeberger, K., Vilhjalmsson, B., Akashi, R., Stougaard, J., Sato, S., Schierup, M. H. & Andersen, S. U., 2020, In: Nature Communications. 11, 1, 15 p., 253.

Performing highly efficient genome scans for local adaptation with R package pcadapt version 4

Privé, F., Luu, K., Vilhjálmsson, B. J. & Blum, M. G. B., 2020, In: Molecular Biology and Evolution. 37, 7, p. 2153-2154 2 p.

Polygenic risk and conversion from depression to bipolar disorder

Musliner, K., Vilhjálmsson, B. J., Agerbo, E., Zandi, P. P., Mortensen, P. B., Børglum, A. & Østergaard, S. D., 1 Dec 2019.

Headaches and polygenic scores

Vilhjálmsson, B. J. & Privé, F. F., Dec 2019, In: Neurology: Genetics. 5, 6, p. e364 2 p.

Making the Most of Clumping and Thresholding for Polygenic Scores

Privé, F., Vilhjálmsson, B. J., Aschard, H. & Blum, M. G. B., Dec 2019, In: American Journal of Human Genetics. 105, 6, p. 1213-1221

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia

Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., Timmermann, A., Grove, J., Mok, P. L. H., Webb, R. T., Sabel, C. E., Hertel, O., Sigsgaard, T., Erikstrup, C., Hougaard, D. M., Werge, T., Nordentoft, M., Børglum, A. D., Mors, O., Mortensen, P. B., Brandt, J., Geels, C. & Pedersen, C. B., Nov 2019, In: JAMA network open. 2, 11, e1914401.

Absolute risk of major depression associated with the polygenic risk score for depression, parental socio-economic status and history of mental disorders: A danish population-based study

Agerbo, E., Trabjerg, B. B., Schork, A. J., Vilhjálmsson, B. J., Albiñana Climent, C., Wray, N. R., Werge, T., Børglum, A., Mors, O., Nordentoft, M., Hougaard, D., Musliner, K., Mortensen, P. B. & McGrath, J. J., 1 Oct 2019, p. S87-S88.

Towards precision medicine in psychiatric care: Using polygenic risk scores to predict outcomes in hospital-treated depression patients

Musliner, K., Vilhjálmsson, B. J., Albiñana Climent, C., Krebs, M. D., Zandi, P. P., Agerbo, E., Mortensen, P. B., Werge, T., Børglum, A. & Østergaard, S. D., Oct 2019, p. S88-S88. 1 p.

Transgenerational effects of inter-ploidy cross direction on reproduction and F2 seed development of Arabidopsis thaliana F1 hybrid triploids

Duszynska, D., Vilhjalmsson, B., Castillo Bravo, R., Swamidatta, S., Juenger, T. E., Donoghue, M. T. A., Comte, A., Nordborg, M., Sharbel, T. F., Brychkova, G., McKeown, P. C. & Spillane, C., Sept 2019, In: Plant Reproduction. 32, 3, p. 275-289 15 p.

Association mapping and disease: Evolutionary perspectives

Besenbacher, S., Mailund, T., Vilhjálmsson, B. J. & Schierup, M. H., 2019, Evolutionary genomics: Statistical and computational methods. Anisimova, M. (ed.). 2 ed. Springer, p. 533-553 21 p. (Methods in Molecular Biology, Vol. 1910).

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

Zheng, J., Richardson, T. G., Millard, L. A. C., Hemani, G., Elsworth, B. L., Raistrick, C. A., Vilhjalmsson, B., Neale, B. M., Haycock, P. C., Smith, G. D. & Gaunt, T. R., 1 Aug 2018, In: GigaScience. 7, 8, p. 1-10 10 p.

The nature of nurture: Effects of parental genotypes

Kong, A., Thorleifsson, G., Frigge, M. L., Vilhjalmsson, B. J., Young, A. I., Thorgeirsson, T. E., Benonisdottir, S., Oddsson, A., Halldorsson, B. V., Masson, G., Gudbjartsson, D. F., Helgason, A., Bjornsdottir, G., Thorsteinsdottir, U. & Stefansson, K., 26 Jan 2018, In: Science. 359, 6374, p. 424-428 5 p.

Covariate selection for association screening in multiphenotype genetic studies

Aschard, H., Guillemot, V., Vilhjalmsson, B., Patel, C. J., Skurnik, D., Ye, C. J., Wolpin, B., Kraft, P. & Zaitlen, N., 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1789-1795 7 p.

Summary Statistic GWAS Joint Re-Analyses Across 30+Traits

Lasry, C., Guillemot, V., Lechat, P., Menager, H., Vilhjalmsson, B. J. & Aschard, H., Nov 2017, In: Genetic Epidemiology. 41, 7, p. 652-652 1 p.

Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity

Athanasiadis, G., Cheng, J. Y., Vilhjálmsson, B. J., Jørgensen, F. G., Als, T. D., Le Hellard, S., Espeseth, T., Sullivan, P. F., Hultman, C. M., Kjærgaard, P. C., Schierup, M. H. & Mailund, T., 17 Aug 2016, In: Genetics. 204, 2, p. 711-722

Response to Day et al

Aschard, H., Vilhjálmsson, B. J., Joshi, A. D., Price, A. L. & Kraft, P., 4 Feb 2016, In: American Journal of Human Genetics. 98, 2, p. 394-5 2 p.

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P-R., Bhatia, G., Do, R., Hayeck, T., Won, H-H., Kathiresan, S., Pato, M., Pato, C., Tamimi, R., Stahl, E., Zaitlen, N., Pasaniuc, B., Belbin, G., Kenny, E. E., Schierup, M. H., De Jager, P., Patsopoulos, N. A., McCarroll, S., Daly, M., Purcell, S., Chasman, D., Neale, B., Goddard, M., Visscher, P. M., Kraft, P., Patterson, N., Price, A. L., Schizophrenia Working Group of the Psychiatric Genomics Consortium (Jakob Grove, member), Grove, J. (ed.), Schizophrenia Working Group of the Psychiatric Genomics Consortium (Anders Børglum, member of -) & Børglum, A., 1 Oct 2015, In: American Journal of Human Genetics. 97, 4, p. 576-92 17 p.

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis

Agerbo, E., Sullivan, P. F., Vilhjálmsson, B. J., Pedersen, C. B., Mors, O., Børglum, A. D., Hougaard, D. M., Hollegaard, M. V., Meier, S., Mattheisen, M., Ripke, S., Wray, N. R. & Mortensen, P. B., Jul 2015, In: J A M A Psychiatry.

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

Hayeck, T. J., Zaitlen, N. A., Loh, P-R., Vilhjálmsson, B. J., Pollack, S., Gusev, A., Yang, J., Chen, G-B., Goddard, M. E., Visscher, P. M., Patterson, N. & Price, A. L., 14 Apr 2015, In: American Journal of Human Genetics.

Adjusting for heritable covariates can bias effect estimates in genome-wide association studies

Aschard, H., Vilhjálmsson, B. J., Joshi, A. D., Price, A. L. & Kraft, P., 5 Feb 2015, In: American Journal of Human Genetics. 96, 2, p. 329-39 11 p.

Efficient Bayesian mixed-model analysis increases association power in large cohorts

Loh, P-R., Tucker, G., Bulik-Sullivan, B. K., Vilhjálmsson, B. J., Finucane, H. K., Salem, R. M., Chasman, D. I., Ridker, P. M., Neale, B. M., Berger, B., Patterson, N. & Price, A. L., 2 Feb 2015, In: Nature Genetics.

DNA methylation in Arabidopsis has a genetic basis and shows evidence of local adaptation

Dubin, M. J., Zhang, P., Meng, D., Remigereau, M-S., Osborne, E. J., Paolo Casale, F., Drewe, P., Kahles, A., Jean, G., Vilhjálmsson, B. J., Jagoda, J., Irez, S., Voronin, V., Song, Q., Long, Q., Rätsch, G., Stegle, O., Clark, R. M. & Nordborg, M., 2015, In: eLife. 4

Leveraging population admixture to characterize the heritability of complex traits

Zaitlen, N., Pasaniuc, B., Sankararaman, S., Bhatia, G., Zhang, J., Gusev, A., Young, T., Tandon, A., Pollack, S., Vilhjálmsson, B. J., Assimes, T. L., Berndt, S. I., Blot, W. J., Chanock, S., Franceschini, N., Goodman, P. G., He, J., Hennis, A. J. M., Hsing, A., Ingles, S. A., Isaacs, W., Kittles, R. A., Klein, E. A., Lange, L. A., Nemesure, B., Patterson, N., Reich, D., Rybicki, B. A., Stanford, J. L., Stevens, V. L., Strom, S. S., Whitsel, E. A., Witte, J. S., Xu, J., Haiman, C., Wilson, J. G., Kooperberg, C., Stram, D., Reiner, A. P., Tang, H. & Price, A. L., Dec 2014, In: Nature Genetics. 46, 12, p. 1356-62 7 p.

Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin

He, B. Z., Ludwig, M. Z., Dickerson, D. A., Barse, L., Arun, B., Vilhjálmsson, B. J., Jiang, P., Park, S-Y., Tamarina, N. A., Selleck, S. B., Wittkopp, P. J., Bell, G. I. & Kreitman, M., Feb 2014, In: Genetics. 196, 2, p. 557-67 11 p.

Genome-wide association study of Arabidopsis thaliana leaf microbial community

Horton, M. W., Bodenhausen, N., Beilsmith, K., Meng, D., Muegge, B. D., Subramanian, S., Vetter, M. M., Vilhjálmsson, B. J., Nordborg, M., Gordon, J. I. & Bergelson, J., 2014, In: Nature Communications. 5, p. 5320

Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies

Aschard, H., Vilhjálmsson, B. J., Greliche, N., Morange, P-E., Trégouët, D-A. & Kraft, P., 2014, In: American Journal of Human Genetics. 94, 5, p. 662-76 15 p.

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., Kähler, A. K., Hultman, C. M., Purcell, S. M., McCarroll, S. A., Daly, M., Pasaniuc, B., Sullivan, P. F., Neale, B. M., Wray, N. R., Raychaudhuri, S., Price, A. L. & Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members), 2014, In: American Journal of Human Genetics. 95, 5, p. 535-52 18 p.

Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden

Long, Q., Rabanal, F. A., Meng, D., Huber, C. D., Farlow, A., Platzer, A., Zhang, Q., Vilhjálmsson, B. J., Korte, A., Nizhynska, V., Voronin, V., Korte, P., Sedman, L., Mandáková, T., Lysak, M. A., Seren, Ü., Hellmann, I. & Nordborg, M., Aug 2013, In: Nature Genetics. 45, 8, p. 884-90 7 p.

Genetic architecture of skin and eye color in an African-European admixed population

Beleza, S., Johnson, N. A., Candille, S. I., Absher, D. M., Coram, M. A., Lopes, J., Campos, J., Araújo, I. I., Anderson, T. M., Vilhjálmsson, B. J., Nordborg, M., Correia E Silva, A., Shriver, M. D., Rocha, J., Barsh, G. S. & Tang, H., Mar 2013, In: PLoS genetics. 9, 3, p. e1003372

The nature of confounding in genome-wide association studies

Vilhjálmsson, B. J. & Nordborg, M., Jan 2013, In: Nature Reviews. Genetics. 14, 1, p. 1-2 2 p.

JAWAMix5: an out-of-core HDF5-based java implementation of whole-genome association studies using mixed models

Long, Q., Zhang, Q., Vilhjálmsson, B. J., Forai, P., Seren, Ü. & Nordborg, M., 2013, In: Bioinformatics. 29, 9, p. 1220-2 3 p.

Quantifying missing heritability at known GWAS loci

Gusev, A., Bhatia, G., Zaitlen, N., Vilhjálmsson, B. J., Diogo, D., Stahl, E. A., Gregersen, P. K., Worthington, J., Klareskog, L., Raychaudhuri, S., Plenge, R. M., Pasaniuc, B. & Price, A. L., 2013, In: PLoS genetics. 9, 12, p. e1003993

GWAPP: a web application for genome-wide association mapping in Arabidopsis

Seren, Ü., Vilhjálmsson, B. J., Horton, M. W., Meng, D., Forai, P., Huang, Y. S., Long, Q., Segura, V. & Nordborg, M., Dec 2012, In: Plant Cell. 24, 12, p. 4793-805 13 p.

A mixed-model approach for genome-wide association studies of correlated traits in structured populations

Korte, A., Vilhjálmsson, B. J., Segura, V., Platt, A., Long, Q. & Nordborg, M., Sept 2012, In: Nature Genetics. 44, 9, p. 1066-71 6 p.

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

Segura, V., Vilhjálmsson, B. J., Platt, A., Korte, A., Seren, Ü., Long, Q. & Nordborg, M., Jul 2012, In: Nature Genetics. 44, 7, p. 825-30 6 p.

Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel

Horton, M. W., Hancock, A. M., Huang, Y. S., Toomajian, C., Atwell, S., Auton, A., Muliyati, N. W., Platt, A., Sperone, F. G., Vilhjálmsson, B. J., Nordborg, M., Borevitz, J. O. & Bergelson, J., Feb 2012, In: Nature Genetics. 44, 2, p. 212-6 5 p.

Analysis and visualization of Arabidopsis thaliana GWAS using web 2.0 technologies

Huang, Y. S., Horton, M., Vilhjálmsson, B. J., Seren, U., Meng, D., Meyer, C., Ali Amer, M., Borevitz, J. O., Bergelson, J. & Nordborg, M., 2011, In: Database: The Journal of Biological Databases and Curation. 2011, p. bar014

Conditions under which genome-wide association studies will be positively misleading

Platt, A., Vilhjálmsson, B. J. & Nordborg, M., Nov 2010, In: Genetics. 186, 3, p. 1045-52 8 p.

Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines

Atwell, S., Huang, Y. S., Vilhjálmsson, B. J., Willems, G., Horton, M., Li, Y., Meng, D., Platt, A., Tarone, A. M., Hu, T. T., Jiang, R., Muliyati, N. W., Zhang, X., Amer, M. A., Baxter, I., Brachi, B., Chory, J., Dean, C., Debieu, M., de Meaux, J., Ecker, J. R., Faure, N., Kniskern, J. M., Jones, J. D. G., Michael, T., Nemri, A., Roux, F., Salt, D. E., Tang, C., Todesco, M., Traw, M. B., Weigel, D., Marjoram, P., Borevitz, J. O., Bergelson, J. & Nordborg, M., 3 Jun 2010, In: Nature. 465, 7298, p. 627-31 5 p.

Projects

NCHAIN: Forging strong links in the organic nitrogen chain

Andersen, S. U., Janss, L., Asp, T., Vilhjálmsson, B. J., Young, P., Roulund, N., Jensen, C. S., Schierup, M. H., Stougaard, J. & Knight, B.

01/01/2015 → 31/12/2019