Aarhus University Seal / Aarhus Universitets segl

Anni Hangaard Andersen

  1. 2020
  2. Published

    Different camptothecin sensitivities in subpopulations of colon cancer cells correlate with expression of different phospho-isoforms of topoisomerase i with different activities. / Tesauro, Cinzia; Keller, Josephine Geertsen; Gromova, Irina; Gromov, Pavel; Frøhlich, Rikke; Erlandsen, Jens Uldum; Andersen, Anni H.; Stougaard, Magnus; Knudsen, Birgitta R.

    In: Cancers, Vol. 12, No. 5, 1240, 05.2020.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. 2019
  4. Published

    Abortive activity of Topoisomerase I : a challenge for genome integrity? / Jakobsen, Kristoffer Pors; Andersen, Anni H.; Bjergbaek, Lotte.

    In: Current Genetics, Vol. 65, No. 5, 10.2019, p. 1141-1144.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  5. Published

    Minimal Resection Takes Place during Break-Induced Replication Repair of Collapsed Replication Forks and Is Controlled by Strand Invasion. / Jakobsen, Kristoffer P.; Nielsen, Kirstine O.; Løvschal, Katrine V.; Rødgaard, Morten; Andersen, Anni H.; Bjergbæk, Lotte.

    In: Cell Reports, Vol. 26, No. 4, e3, 01.2019, p. 836-844.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2017
  7. Published

    Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events. / Kristoffersen, Emil L; Jørgensen, Asger Givskov; Jørgensen, Line A; Jensen, Pia W; W Byl, Jo Ann; Osheroff, Neil; Andersen, Anni H; Stougaard, Magnus; Ho, Yi-Ping; Knudsen, Birgitta R.

    In: Nucleic Acids Research, Vol. 45, No. 13, 27.07.2017, p. 7855-7869.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2015
  9. Published

    Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination. / Mundbjerg, Kamilla; Jørgensen, Signe W; Fredsøe, Jacob; Nielsen, Ida; Pedersen, Jakob Madsen; Bentsen, Iben Bach; Lisby, Michael; Bjergbaek, Lotte; Andersen, Anni H.

    In: P L o S Genetics, Vol. 11, No. 12, 02.12.2015, p. e1005697.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation. / Roedgaard, Morten; Fredsoe, Jacob; Pedersen, Jakob Madsen; Bjergbaek, Lotte; Andersen, Anni Hangaard.

    In: PLOS ONE, Vol. 10, No. 7, e0132739, 14.07.2015, p. 1-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. 2013
  12. Published

    A Rad53 Independent Function of Rad9 Becomes Crucial for Genome Maintenance in the Absence of the RecQ Helicase Sgs1. / Nielsen, Ida; Bentsen, Iben Bach; Andersen, Anni Hangaard; Gasser, Susan M.; Bjergbæk, Lotte.

    In: P L o S One, Vol. 8, No. 11, e81015, 20.11.2013.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    The importance of topoisomerases for chromatin regulated genes. / Fredsøe, Jacob Christian; Pedersen, Jakob Madsen; Rødgaard, Morten Terpager; Andersen, Anni Hangaard.

    2013.

    Research output: Contribution to conferencePosterResearch

  14. Published

    DNA hairpins as temperature switches, thermometers and ionic detectors. / Jonstrup, Anette Thyssen; Fredsøe, Jacob Christian; Andersen, Anni Hangaard.

    In: Sensors, Vol. 13, No. 5, 05.05.2013, p. 5937-5944.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    MRX protects fork integrity at protein–DNA barriers, and its absence causes checkpoint activation dependent on chromatin context. / Bentsen, Iben Bach; Nielsen, Ida; Lisby, Michael; Nielsen, Helena Berner Nedergaard; Sen Gupta, Souvik; Mundbjerg, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    In: Nucleic Acids Research, Vol. 41, No. 5, 01.02.2013, p. 3173-3189.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. 2012
  17. Published

    DNA Topoisomerases Maintain Promoters in a State Competent for Transcriptional Activation in Saccharomyces cerevisiae. / Pedersen, Jakob Madsen; Fredsøe, Jacob Christian; Rødgaard, Morten Terpager; Andreasen, Lotte; Mundbjerg, Kamilla; Kruhøffer, Mogens; Brinch, Marie; Schierup, Mikkel Heide; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    In: P L o S Genetics, Vol. 8, No. 12 e1003128, 20.12.2012, p. 1-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Studying repair of a single protein-bound nick in vivo using the Flp-nick system. / Nielsen, Ida; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    DNA repair protocols. ed. / Lotte Bjergbæk. Vol. 920 Humana Press, 2012. p. 393-415 (Methods in Molecular Biology, Vol. 920).

    Research output: Contribution to book/anthology/report/proceedingBook chapterCommunication

  19. 2011
  20. Published

    Completion of unidirectional replication requires Top2 or Sgs1. / Mundbjerg, Kamilla; Nielsen, Ida; Bentsen, Iben Bach; Lisby, Michael; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    2011.

    Research output: Contribution to conferencePosterResearch

  21. Published

    The MRX complex is required for replisome integrity as revealed from genomic loci with unidirectional replication. / Bentsen, Iben Bach; Nielsen, Ida; Nielsen, Helena Berner Nedergaard; Mundbjerg, Kamilla; Lisby, Michael; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    2011. Poster session presented at Keystone Symposia, DNA replication and recombination, Keystone, Colorado, United States.

    Research output: Contribution to conferencePosterResearch

  22. 2010
  23. Published

    A Flp-nick system to study repair of a single protein-bound nick in vivo. / Nielsen, Ida; Bentsen, Iben Bach; Lisby, Michael; Hansen, Sabine; Jørgensen, Natasja Leth; Mundbjerg, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    2010. Poster session presented at Biological impact of alternatively structured DNA, FASEB summer research conference, Steamboat Springs, Colorado, United States.

    Research output: Contribution to conferencePosterResearch

  24. Published

    Detection of DNA Topoisomerase I and Related Enzyme Activities at the Single Molecule Level. / Andersen, Félicie Faucon; Stougaard, Magnus; Tesauro, Cinzia; Tordrup, David Paul; Jensen, Sissel Juul; Bendsen, Simon Peter; Nielsen, Christine Juul Fælled; Orecchioni, Stefania; Andersen, Anni Hangaard; Koch, Jørn Erland; Knudsen, Birgitta R.

    2010. Poster session presented at 8th Annual iNANO meeting, Århus, Denmark.

    Research output: Contribution to conferencePosterResearch

  25. Published

    Detection of DNA topoisomerase I and related enzyme activities at the single molecule level. / Jensen, Sissel Juul; Andersen, Félicie Faucon; Stougaard, Magnus; Tesauro, Cinzia; Tordrup, David Paul; Bendsen, Simon Peter; Andersen, Anni Hangaard; Koch, Jørn Erland; Knudsen, Birgitta R.

    2010. Poster session presented at Foundations of Nanosciences Self-assembled Architectures and Devices, Snowbird, United States.

    Research output: Contribution to conferencePosterResearch

  26. Published

    Dissection of the genome-wide transcriptional response to lack of DNA topoisomerase activity in the chromatin context. / Pedersen, Jakob Madsen; Andreasen, Lotte; Fredsøe, J.; Kruhøffer, Mogens; Andersen, Anni Hangaard.

    2010. Abstract from Molecular Basis for Chromatin Structure and Regulation, Taos, New Mexico, .

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  27. Published

    Mitotic chromosomes are constrained by topoisomerase II-sensitive DNA entanglements. / Kawamura, R.; Pope, L. H.; Christensen, M.O.; Sun, M.; Terekhova, K.; Boege, F.; Mielke, C.; Andersen, Anni Hangaard; Marco, J.F.

    In: Journal of Cell Biology, Vol. 8, 2010, p. 653-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. Published

    The importance of DNA topoisomerases and DNA topology for genome and transcriptome maintenance. / Mundbjerg, Kamilla; Pedersen, Jakob Madsen; Nielsen, Ida; Fredsøe, Jacob Christian; Christensen, Helene; Ingerslev, Anne Krog; Jørgensen, Signe Winther; Pedersen, Lea Hougaard; Andersen, Anni Hangaard.

    2010. Poster session presented at MBI Annual Meeting 2010, .

    Research output: Contribution to conferencePosterResearch

  29. 2009
  30. Published

    A Flp-nick system to study repair of a single protein-bound nick in vivo. / Nielsen, Ida; Bentsen, Iben Bach; Lisby, M.; Hansen, S.; Mundbjerg, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    In: Nature Methods, 2009, p. 753-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    A Flp-nick system to study repair of a single protein-bound nick in vivo -  a model system for repair of Top1-DNA cleavage intermediates. / Nielsen, Ida; Bentsen, Iben Bach; Hansen, Sabine; Mundbjerg, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    2009. Poster session presented at Chromatin, Replication and Chromosomal Stability Conference, Copenhagen, .

    Research output: Contribution to conferencePosterResearch

  32. Published

    Casein Kinase Iδ/ε Phosphorylates serine 1106 in Topoisomerase IIα and Regulates Cleavable Complex Formation. / Grozav, A.G.; Chikamori, K.; Kozuki, T.; Grabowski, D.R.; Bukowski, R.M.; Kinter, M.; Andersen, Anni Hangaard; Ganapathi, R.; Ganapathi, M.K.

    In: Nucleic Acids Research, Vol. 37, 2009, p. 382-92.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Multiplexed Detection of Site Specific Recombinase and DNA Topoisomerase Activities at the Single Molecule Level. / Andersen, Félicie Faucon; Stougaard, Magnus; Jørgensen, Hanne Lærke; Bendsen, Simon Peter; Jensen, Sissel Juul; Hald, Kristoffer; Andersen, Anni Hangaard; Koch, Jørn Erland; Knudsen, Birgitta R.

    In: A C S Nano, Vol. 3, No. 12, 2009.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Roles of Topoisomerase I and II in the S Phase of the Cell Cycle. / Mundbjerg, Kamilla; Nielsen, Ida; Bentsen, Iben Bach; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    2009. Poster session presented at MBI Annual Meeting 2009, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Roles of topoisomerase I and II in the S phase of the cell cycle. / Mundbjerg, Kamilla; Nielsen, Ida; Bentsen, Iben Bach; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    2009. Poster session presented at Chromatin, Replication and Chromosomal Stability Conference, Copenhagen, .

    Research output: Contribution to conferencePosterResearch

  36. Published

    Studies of replication fork management upon the encounter with a protein-DNA barrier at a single genomic site. / Bentsen, Iben Bach; Nielsen, Ida; Mundbjerg, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    2009. Abstract from MBI Annual Meeting 2009, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  37. Published

    Studies of replication fork management upon the  encounter with a protein-DNA barrier at a single genomic site. / Bentsen, Iben Bach; Nielsen, Ida; Mundbjerg, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    2009. Poster session presented at Chromatin, Replication and Chromosomal Stability Conference, Copenhagen, .

    Research output: Contribution to conferencePosterResearch

  38. Published

    The QTK-loop is Essential for the Communication Between the N-terminal ATPase Domain and the Central Cleavage/Ligation Domain in Human Topoisomerase IIα. / Bendsen, Simon Peter; Østergaard, Vibe Hallundbæk; Skouboe, Camilla; Brinch, Marie; Knudsen, Birgitta R.; Andersen, Anni Hangaard.

    In: Biochemistry, 2009, p. 6508-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  39. Published

    Top2 or Sgs1 are necessary to avoid checkpoint activation in late S phase. / Mundbjerg, Kamilla; Nielsen, Ida; Bentsen, Iben Bach; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    2009. Poster session presented at Eukaryotic DNA replication and genome maintenance, Cold Spring Harbor, United States.

    Research output: Contribution to conferencePosterResearch

  40. 2008
  41. Published

    Assembly and structural analysis of a covalently closed nano-scale DNA cage. / Andersen, Félicie Faucon; Knudsen, Bjarne; Oliveira, Cristiano Luis Pinto De; Hougaard, Rikke Frøhlich; Krüger, Dinna; Bungert, Jörg; Agbandje-McKenna, Mavis; McKenna, Robert; Jensen, Sissel Juul; Veigaard, Christopher; Koch, Jørn; Rubinstein, John L; Guldbrandtsen, Bernt; Hede, Marianne Smedegaard; Karlsson, Göran; Andersen, Anni Hangaard; Pedersen, Jan Skov; Knudsen, Birgitta R.

    In: Nucleic Acids Research, Vol. 36, No. 4, 2008, p. 1113-1119.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  42. Published

    Bimodal Recognition of DNA Geometry by Human Topoisomerase IIα: Preferential Relaxation of Positively Supercoiled DNA Requires Elements in the C-terminal Domain. / McClendon, A.; Gentry, A.; Dickey, J.; Brinch, Marie; Bendsen, Simon Peter; Andersen, Anni Hangaard; Osheroff, N.

    In: Biochemistry, Vol. 47, 2008, p. 13169-78.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Construction and Characterization of topologically interlinked DNA nano-structures. / Nielsen, Christine J. F.; Jørgensen, Hanne L.; Tordrup, David Paul; Jensen, Sissel Juul; Nielsen, Laura Raagaard; Oliveira, Cristiano; Desideri, Alessandro; Falconi, Mattia; Oteri, Francesco; Ludtke, Steven; Serysheva, Irina; Knudsen, Bjarne; Pedersen, Jan Skov; Andersen, Anni Hangaard; Knudsen, Birgitta R.; Andersen, Félicie Faucon.

    2008. Poster session presented at DNA Topoisomerases in Biology and Medicine, United Kingdom.

    Research output: Contribution to conferencePosterResearch

  44. Published

    DNA topoisomerases - Cellular tools with huge impact on genome stability. / Mundbjerg, Kamilla; Pedersen, Jakob Madsen; Bendsen, Simon; Andreasen, Lotte; Knudsen, Birgitta R.; Bjergbaek, Lotte; Andersen, Anni Hangaard.

    2008. Abstract from Eighth international conference of anticancer research, Kos, Greece.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  45. Published

    Genomic transcriptional response to loss of topoisomerase I and II activity in S. cerevisiae. / Andreasen, Lotte; Pedersen, Jakob Madsen; Kristensen, Kamilla; Brinch, Marie; Kruhøffer, Mogens; Andersen, Anni Hangaard.

    2008. Poster session presented at EMBO workshop: DNA supercoiling and topoisomerases, France.

    Research output: Contribution to conferencePosterResearch

  46. Published

    Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase II alpha. / Jonstrup, Anette Thyssen; Thomsen, Tina; Wang, Yong; Knudsen, Birgitta R; Koch, Jørn; Andersen, Anni H.

    In: Nucleic Acids Research, Vol. 36, No. 19, 2008, p. 6165-74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Identification of protein factors required during stalled replication at a protein-DNA barrier. / Bentsen, Iben Bach; Nielsen, Ida; Kristensen, Kamilla; Andersen, Anni Hangaard; Bjergbæk, Lotte.

    2008. Poster session presented at DNA replication and recombination, Santa Fe, United States.

    Research output: Contribution to conferencePosterResearch

  48. 2007
  49. Published

    Determination of S Phase Specific Roles of Topoisomerase I and II Based on Interactions with Sgs1. / Mundbjerg, Kamilla; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    2007. Poster session presented at MBI Annual Meeting 2007, Aarhus, Denmark.

    Research output: Contribution to conferencePosterResearch

  50. Published

    Functions of the N-terminal Domain in Human Topoisomerase I. / Hougaard, Rikke Frølich; Veigaard, Christopher; Andersen, Félicie Faucon; McClendon, A. Kathleen; Gentry, Amanda; Jensen, Sissel Juul; Mandau, Brian Høck; Kjeldsen, Eigil; Andersen, Anni Hangaard; Osheroff, Neil; Knudsen, Birgitta R.

    2007. Abstract from Functions of the N-terminal Domain in Human Topoisomerase I, .

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  51. Published

    Human Topoisomerase I as an SR-protein Specific Kinase. / Nguyen, Ngoc Hang Thi; Nielsen, Maria Bjerre; Tordrup, David Paul; Andersen, Anni Hangaard; Knudsen, Birgitta R.; Andersen, Félicie Faucon.

    2007. Abstract from Human Topoisomerase I as an SR-protein Specific Kinase, .

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  52. Published

    Resolution of Holliday junction substrates by human topoisomerase I. / Hede, Marianne S.; Petersen, Rikke L.; Krüger, Dinna; Andersen, Félicie Faucon; Andersen, Anni Hangaard; Knudsen, Birgitta R.

    In: Journal of Molecular Biology, 2007.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Role for the N-terminal domain of Human Topoisomerase I in vivo. / Mandau, Brian Høck; Jensen, Sissel Juul; Hougaard, Rikke Frølich; Veigaard, Christopher; Kjeldsen, Eigil; Andersen, Félicie Faucon; Andersen, Anni Hangaard; Knudsen, Birgitta R.

    2007. Abstract from Role for the N-terminal domain of Human Topoisomerase I in vivo, .

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  54. Published

    Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. / Frøhlich, Rikke F; Veigaard, Christopher; Andersen, Félicie Faucon; McClendon, A.K.; Gentry, A.K.; Andersen, Anni Hangaard; Osherroff, N.; Stevnsner, Tinna V.; Knudsen, Birgitta R.

    In: Nucleic Acid Res., Vol. 35, 2007, p. 6170-6180.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. 2006
  56. Published

    Stimulated activity of human topoisomerase IIα and IIβ on RNA containing substrates. / Wang, Y.; Knudsen, Birgitta R.; Bjergbæk, Lotte; Westergaard, Ole; Andersen, Anni Hangaard.

    In: Journal of Biological Chemistry, Vol. 274, 2006, p. 22839-22846.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. 2005
  58. Published

    Det usynlige termometer. / Andersen, Anni Hangaard.

    2005, Andet.

    Research output: Other contributionCommunication

  59. Published

    Genome instability as a cause of ageing and cancer: Implications of RecQ helicases. / Skouboe, Camilla; Bjergbæk, Lotte; Andersen, Anni Hangaard.

    In: Signal Transduction, Vol. 3, 2005, p. 142-151.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearch

  60. 2004
  61. Published

    Dissecting the cell killing mechanism of the topoisomerase II targeting drug ICRF-193. / Østergaard, V.H.; Knudsen, B.R.; Andersen, A.H.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 28100-28105.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  62. Published

    Hindering the strand passage reaction of human topoisomerase II alpha without disturbing DNA cleavage, ATP hydrolysis or operation of the N-terminal clamp. / Østergaard, V.H.; Giangiacomo, L.; Bjergbæk, L.; Knudsen, B.R.; Andersen, A.H.

    In: Journal of Biological Chemistry, Vol. 279, 2004, p. 28093-28099.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  63. Published

    Indiske Ph.D.-studerende vil til Danmark. / Andersen, Anni Hangaard; Knudsen, Birgitta R.

    In: AU-gustus, 2004.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

  64. Published

    Indiske Ph.D.-studerende vil til Danmark. / Andersen, Anni Hangaard; Knudsen, Birgitta R.

    In: CAMPUS, Vol. 6, 2004.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleCommunication

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