Aarhus University Seal / Aarhus Universitets segl

Anni Christensen

  1. 2019
  2. Published

    Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion. / Dupont, Marie Alice; Humbert, Camille; Huber, Céline; Siour, Quentin; Guerrera, Ida Chiara; Jung, Vincent; Christensen, Anni; Pouliet, Aurore; Garfa-Traore, Meriem; Nitschké, Patrick; Injeyan, Marie; Millar, Kathryn; Chitayat, David; Shannon, Patrick; Girisha, Katta Mohan; Shukla, Anju; Mechler, Charlotte; Lorentzen, Esben; Benmerah, Alexandre; Cormier-Daire, Valérie; Jeanpierre, Cécile; Saunier, Sophie; Delous, Marion.

    In: Human Molecular Genetics, Vol. 28, No. 16, 15.08.2019, p. 2720-2737.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors. / Jendroszek, Agnieszka; Madsen, Jeppe B; Chana-Muñoz, Andrés; Dupont, Daniel M; Christensen, Anni; Panitz, Frank; Füchtbauer, Ernst-Martin; Lovell, Simon C; Jensen, Jan K.

    In: The Journal of Biological Chemistry, Vol. 294, No. 10, 03.2019, p. 3794-3805.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. 2018
  5. Published

    Crystal structure of tetrameric human Rabin8 GEF domain. / Vetter, Melanie; Boegholm, Niels; Christensen, Anni; Bhogaraju, Sagar; Andersen, Marie B; Lorentzen, Anna; Lorentzen, Esben.

    In: Proteins, Vol. 86, No. 4, 10.01.2018, p. 405-413.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. 2017
  7. Published

    Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved. / Jendroszek, Agnieszka; Sønnichsen, Malene; Chana Munoz, Andres; Leyman, Kato; Christensen, Anni; Petersen, Steen Vang; Bendixen, Christian; Panitz, Frank; Andreasen, Peter; Jensen, Jan Kristian.

    In: Thrombosis and Haemostasis, Vol. 117, No. 9, 30.08.2017, p. 1688-1699.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. 2015
  9. Published

    Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. / Jiang, Longguang; Zhao, Baoyu; Xu, Peng; Sørensen, Hans Peter; Jensen, Jan K; Christensen, Anni; Hosseini, Masood; Nielsen, Niels Christian; Jensen, Knud J; Andreasen, Peter A.; Huang, Mingdong.

    In: International Journal of Biochemistry & Cell Biology, Vol. 62, 05.2015, p. 88-92.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. 2014
  11. Published

    A cyclic peptidic serine protease inhibitor : increasing affinity by increasing Peptide flexibility. / Zhao, Baoyu; Xu, Peng; Jiang, Longguang; Paaske, Berit; Kromann-Hansen, Tobias; Jensen, Jan K; Sørensen, Hans Peter; Liu, Zhuo; Nielsen, Jakob Toudahl; Christensen, Anni; Hosseini, Masood; Sørensen, Kasper K; Nielsen, Niels Christian; Jensen, Knud J.; Huang, Mingdong; Andreasen, Peter A.

    In: PLOS ONE, Vol. 9, No. 12, e115872, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. 2012
  13. Published

    Urokinase-type Plasminogen Activator-like Proteases in Teleosts Lack Genuine Receptor-binding Epidermal Growth Factor-like Domains. / Bager, René; Kristensen, Thomas Kielsgaard; Jensen, Jan Kristian; Szczur, Agnieszka; Christensen, Anni; Andersen, Lisbeth Moreau; Johansen, Jesper Sanderhoff; Larsen, Niels; Baatrup, Erik; Huang, Mingdong; Ploug, Michael; Andreasen, Peter.

    In: Journal of Biological Chemistry, Vol. 287, No. 33, 2012, p. 27526-27536.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. 2011
  15. Published

    The binding mechanism of a peptidic cyclic serine protease inhibitor. / Jiang, Longguang; Svane, Anna S P; Sørensen, Hans Peter; Jensen, Jan K; Hosseini, Masood; Chen, Zhuo; Weydert, Caroline; Nielsen, Jakob T; Christensen, Anni; Yuan, Cai; Jensen, Knud Jørgen; Nielsen, Niels Chr; Malmendal, Anders; Huang, Mingdong; Andreasen, Peter.

    In: International Journal of Molecular Biology, Vol. 412, No. 2, 2011, p. 235-50.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. 2010
  17. Published

    RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1. / Madsen, Jeppe B; Dupont, Daniel Miotto; Andersen, Thomas B; Nielsen, Anne F; Sang, Lu; Brix, Ditte M; Jensen, Jan K; Broos, Thomas; Hendrickx, Maarten L V; Christensen, Anni; Kjems, Jørgen; Andreasen, Peter A.

    In: Biochemistry, Vol. 49, No. 19, 18.05.2010, p. 4103-15.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. 2009
  19. Published

    Non-proteolytic induction of catalytic activity into the single-chain form of urokinase-type plasminogen activator by dipeptides. / Bøtkjær, Kenneth Alrø; Byszuk, A.; Andersen, Lisbeth Moreau; Christensen, Anni; Andreasen, Peter; Blouse, Grant.

    In: Biochemistry, Vol. 48, No. 40, 25.08.2009, p. 9606-9617.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. 2008
  21. Published

    A peptide accelerating the conversion of plasminogen activator inhibitor-1 to an inactive latent state. / Mathiasen, Lisa; Dupont, Daniel Miotto; Christensen, Anni; Blouse, Grant; Jensen, Jan Kristian; Gils, Ann; Declerck, Paul J.; Wind, Troels; Andreasen, Peter.

    In: Molecular Pharmacology, Vol. 74, No. 3, 2008, p. 641-653.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Characterisation of a site on pai-1 that binds to vitronectin outside of the somatomedin B domain. / Schar, christine r.; Jensen, Jan Kristian; Christensen, Anni; Blouse, Grant; Peterson, Cynthia B.; Andreasen, Peter.

    In: Journal of Biological Chemistry, Vol. 283, No. 42, 2008, p. 28487-28496.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. 2006
  24. Published

    Evidence for a pre-latent form of the serpin plasminogen activator inhibitor-1 with a detached beta-strand 1C. / Dupont, Daniel M; Blouse, Grant E; Hansen, Martin; Mathiasen, Lisa; Kjelgaard, Signe; Jensen, Jan Kristian; Christensen, Anni; Gils, Ann; Declerck, Paul J; Andreasen, Peter A; Wind, Troels.

    In: Journal of Biological Chemistry, Vol. 281, No. 47, 24.11.2006, p. 36071-81.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis. / Skeldal, Sune; Larsen, Jakob Vejby; Pedersen, Katrine E; Petersen, Helle H; Egelund, Rikke; Christensen, Anni; Jensen, Jan Kristian; Gliemann, Jørgen; Andreasen, Peter A.

    In: F E B S Journal, Vol. 273, No. 22, 01.11.2006, p. 5143-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    Binding areas of Urokinase-type plasminogen activator inhibitor-1 complex for endocytosis receptors of the low density lipoprotein receptor family, determined by site-directed mutagenesis. / Skeldal, Sune; Larsen, J.V.; Pedersen, K.E.; Petersen, H.H.; Egelund, R.; Christensen, Anni; Jensen, J.K.; Gliemann, Jørgen; Andreasen, Peter.

    2006. Poster session presented at Annual Meeting of the " Cancer Degradome", København, Denmark.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Evidence for a prelatent form of plasminogen activator inhibitor-1 with a detached β-strand 1C. / Dupont, Daniel Miotto; Blouse, Grant; Hansen, Martin; Mathiasen, Lisa; Kristiansen, Signe Kjelgaard; Jensen, J.K.; Christensen, Anni; Gils, A.; Declerck, P.J.; Andreasen, Peter; Wind, Troels.

    In: Journal of Biological Chemistry, Vol. 281, 2006, p. 36071-36081.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  28. 2005
  29. Published

    A urokinase-type plasminogen activator-inhibiting cyclic peptide with an unusual P2 residue and an extended protease binding surface demonstrates new modalities for enzyme inhibition. / Hansen, M.; Wind, Troels; Blouse, Grant; Christensen, Anni; Petersen, H.H.; Kjelgaard, S.; Mathiasen, L.; Holtet, T.L.; Andreasen, Peter.

    In: Journal of Biological Chemistry, Vol. 280, 2005, p. 38424-38437.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. 2004
  31. Published

    Plasminogen activator inhibitor-1 and tumour growth, invasion, and metastasis. / Durand, M, K.V.; Bødker, J.S.; Christensen, A.; Dupont, D.M.; Hansen, M.; Jensen, J.K.; Kjelgaard, S.; Mathiasen, L.; Pedersen, K.E.; Skeldal, S.; Wind, T.; Andreasen, P.A.

    In: Thromb. Haemostas., Vol. 91, 2004, p. 438-449.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. 2003
  33. Published

    Vitronectin in human breast carcinomas. / Aaboe, Mads; Offersen, Birgitte Vrou; Christensen, Anni; Andreasen, Peter.

    In: B B A - Molecular Basis of Disease, Vol. 1638, No. 1, 20.05.2003, p. 72-82.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Biochemical importance of glycosylation of plasminogen activator inhibitor-1. / Gils, A.; Pedersen, K.E.; Skottrup, P.; Christensen, A.; Naessens, D.; Deinum, J.; Enghild, J.J.; Declerck, P.J.; Andreasen, P.A.

    In: Thromb. Haemost., Vol. 90, 2003, p. 206-217.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Biochemical mechanism of action of a diketopiperazine inactivator of plasminogen activator inhibitor-1. / Einholm, Anja P; Pedersen, Katrine E; Wind, Troels; Kulig, Paulina; Overgaard, Michael T; Jensen, Jan K; Bødker, Julie S; Christensen, Anni; Charlton, Peter; Andreasen, Peter A.

    In: Biochemical Journal, Vol. 373, No. Pt 3, 2003, p. 723-32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Plasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands. / Pedersen, K.E.; Einholm, A.P.; Christensen, A.; Schack, L.; Wind, T.; Kenney, J.M.; Andreasen, P.A.

    In: Biochem. J., Vol. 372, 2003, p. 747-755.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Plasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands. / Pedersen, Katrine E; Einholm, Anja P; Christensen, Anni; Schack, Lotte; Wind, Troels; Kenney, John M; Andreasen, Peter A.

    In: Biochemical Journal, Vol. 372, No. Pt 3, 2003, p. 747-55.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. 2001
  39. Published

    A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization. / Egelund, R.; Einholm, A.P.; Pedersen, K.E.; Nielsen, R.W.; Christensen, A.; Deinum, J.; Andreasen, P.A.

    In: Journal of Biological Chemistry, Vol. 276, 2001, p. 13077-13086.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  40. Published

    A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization. / Egelund, R; Einholm, A P; Pedersen, K E; Nielsen, R W; Christensen, A; Deinum, J; Andreasen, Peter A.

    In: Journal of Biological Chemistry, Vol. 276, No. 16, 2001, p. 13077-86.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  41. 1999
  42. Published

    Ligand binding properties of the very low density lipoprotein receptor. Absence of the third complement-type repeat encoded by exon 4 is associated with reduced binding of Mr 40,000 receptor-associated protein. / Rettenberger, P M; Oka, K; Ellgaard, L; Petersen, H H; Christensen, A; Martensen, P M; Monard, D; Etzerodt, M; Chan, L; Andreasen, P A.

    In: Journal of Biological Chemistry, Vol. 274, No. 13, 26.03.1999, p. 8973-80.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Oestradiol and basic fibroblast growth factor stimulate expression of very low density lipoprotein receptor and plasminogen activator inhibitor-1 in breast carcinoma cell lines. / Madsen, B.; Martensen, P. M.; Christensen, A.; Andreasen, P. A.

    In: Fibrinolysis and Proteolysis, Vol. 13, No. 1, 01.01.1999, p. 15-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Estradiol and basic fibroblast growth factor stimulate expression of very low density lipoprotein receptor and plasminogen activator inhibitor-1 in breast carcinoma cell lines. / Madsen, B.; Martensen, P.M.; Christensen, A.; Andreasen, P.A.

    In: Fibrinolysis and Proteolysis, Vol. 13, 1999, p. 15-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Ligand binding properties of the very low density lipoprotein receptor. Absence of the third complement-type repeat encoded by exon 4 is associated with reduced binding of Mr 40,000 receptor-associated. / Rettenberger, P.M.; Oka, K.; Ellgaard, L.; Petersen, H.H.; Christensen, A.; Martensen, P.M.; Monard, D.; Etzerodt, M.; Chan, L.; Andreasen, Peter.

    In: Journal of Biological Chemistry, Vol. 274, 1999, p. 8973-8980.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  46. 1997
  47. Published

    Breast carcinoma epithelial cells express a very low density lipoprotein receptor variant lacking the olinked glycosylation domain encoded by exon 16, but with normal binding activity for serine proteinase/serpin complexes and m, 40,000 receptor associated protein. / Martensen, Pia M.; Rettenberger, Peter M.; Christensen, Anni; Oka, Kazuhiro; Christensen, Lise; Petersen, Helle H.; Chan, Lawrence; Heegaard, Christian W.; Andreasen, Peter A.

    In: Fibrinolysis and Proteolysis, Vol. 11, No. SUPPL. 3, 01.12.1997.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  48. Published

    Breast carcinoma epithelial cells express a very low-density lipoprotein receptor variant lacking the O-linked glycosylation domain encoded by exon 16, but with full binding activity for serine proteinase/serpin complexes and Mr-40,000 receptor-associated protein. / Martensen, P M; Oka, K; Christensen, L; Rettenberger, P M; Petersen, H H; Christensen, A; Chan, L; Heegaard, C W; Andreasen, P A.

    In: European Journal of Biochemistry, Vol. 248, No. 2, 01.09.1997, p. 583-91.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  49. Published

    Breast carcinoma epithelial cells express a very low density lipoprotein receptor variant lacking the O-linked glycosylation domain encoded by exon 16, but with full binding activity for serine proteinase/serpin complex and Mr 40,000 receptor associated protein. / Martensen, Pia Møller; kazuhiro, Oka; Rettenberger, Peter M.; Petersen, Helle H.; Christensen, Anni; Lawrence, Chang; Heegaard, Christian Wurtz; Andreasen, Peter.

    In: F E B S Journal, Vol. 248, 1997, p. 583-591.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  50. Published

    Specificity of serine proteinase/serpin complex binding to very low density lipoprotein receptor and α2-macroglobulin receptor /LDL-receptor-related protein. / Kasza, Aneta; Petersen, Helle H.; Heegaard, Christian Wurtz; Oka, Kazuhiro; Christensen, Anni; Dubin, Adam; Chan, Lawrence; Andreasen, Peter.

    In: F E B S Journal, Vol. 248, 1997, p. 270-281.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  51. 1995
  52. Published

    Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex. / Heegaard, Christian Wurtz; Wiborg Simonsen, Anna Carina; Oka, Kazuhiro; Kjøller, Lars; Christensen, Anni; Madsen, Bente; Ellgaard, Lars; Chan, Lawrence; Andreasen, Peter.

    In: Journal of Biological Chemistry, Vol. 270, 1995.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. 1994
  54. Published

    Very low density lipoprotein receptor from mammary gland and mammary epithelial cell lines binds and mediates endocytosis of M(r) 40,000 receptor associated protein. / Wiborg Simonsen, Anna Carina; Heegaard, Christian Wurtz; Rasmussen, Lone K.; Ellgaard, Lars; Kjøller, Lars; Christensen, Anni; Etzerodt, Michael; Andreasen, Peter.

    In: F E B S Letters, Vol. 354, 1994, p. 279-283.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review