Anne-Mette Lange

Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder: A Secondary Analysis of Data From a Randomized Controlled Trial

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Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder : A Secondary Analysis of Data From a Randomized Controlled Trial. / Larsen, Liva Bundgaard; Daley, David; Lange, Anne Mette; Sonuga-Barke, Edmund; Thomsen, Per Hove; Rask, Charlotte Ulrikka.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 60, No. 6, 2021, p. 734-744.

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Larsen, Liva Bundgaard ; Daley, David ; Lange, Anne Mette ; Sonuga-Barke, Edmund ; Thomsen, Per Hove ; Rask, Charlotte Ulrikka. / Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder : A Secondary Analysis of Data From a Randomized Controlled Trial. In: Journal of the American Academy of Child and Adolescent Psychiatry. 2021 ; Vol. 60, No. 6. pp. 734-744.

Bibtex

@article{adcd8c60a0534435a13ffecbf5121cc7,
title = "Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder: A Secondary Analysis of Data From a Randomized Controlled Trial",
abstract = "Objective: School-age children with attention-deficit/hyperactivity disorder (ADHD) have reduced health-related quality of life (HRQoL), but it is unclear whether this is also true for preschool children. It is unknown whether parent training (PT) improves HRQoL. This study compared HRQoL in preschool children with ADHD with age-matched children from the general population; examined whether PT improves HRQoL; and tested if treatment-related changes in HRQoL were mediated by improvements in ADHD, parent efficacy, and family stress. Method: Parents of 164 children age 3–7 years with an ADHD diagnosis participated in a randomized controlled trial comparing the New Forest Parenting Programme and treatment as usual. Measures of HRQoL, ADHD, parent efficacy, and family stress were completed at baseline, posttreatment, and 36-week follow-up. Child baseline HRQoL was compared with two general population-based reference groups. PT effects were analyzed using linear models and mediation analyses. Results: Preschoolers with ADHD had lower HRQoL than the reference groups. The New Forest Parenting Programme, but not treatment as usual, was associated with improvement in psychosocial HRQoL at posttreatment (change 2.28, 95% CI [0.78, 3.77]) and at 36-week follow-up (change 2.05, 95% CI [0.56, 3.54]). This difference between treatment arms was not statistically significant. Parent efficacy and family stress scores at posttreatment significantly mediated improvements in HRQoL at 36-week follow-up; ADHD scores at posttreatment did not. Conclusion: ADHD negatively impacts HRQoL in early childhood. PT for ADHD has the potential to improve HRQoL independently of its effects on ADHD symptoms. Clinical trial registration information: A Controlled Study of Parent Training in the Treatment of ADHD in Young Children (D'SNAPP); http://clinicaltrial.gov/; NCT01684644.",
keywords = "attention-deficit/hyperactivity disorder, health-related quality of life, parent training, preschool children",
author = "Larsen, {Liva Bundgaard} and David Daley and Lange, {Anne Mette} and Edmund Sonuga-Barke and Thomsen, {Per Hove} and Rask, {Charlotte Ulrikka}",
year = "2021",
doi = "10.1016/j.jaac.2020.04.014",
language = "English",
volume = "60",
pages = "734--744",
journal = "American Academy of Child and Adolescent Psychiatry. Journal",
issn = "0890-8567",
publisher = "Elsevier BV",
number = "6",

}

RIS

TY - JOUR

T1 - Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder

T2 - A Secondary Analysis of Data From a Randomized Controlled Trial

AU - Larsen, Liva Bundgaard

AU - Daley, David

AU - Lange, Anne Mette

AU - Sonuga-Barke, Edmund

AU - Thomsen, Per Hove

AU - Rask, Charlotte Ulrikka

PY - 2021

Y1 - 2021

N2 - Objective: School-age children with attention-deficit/hyperactivity disorder (ADHD) have reduced health-related quality of life (HRQoL), but it is unclear whether this is also true for preschool children. It is unknown whether parent training (PT) improves HRQoL. This study compared HRQoL in preschool children with ADHD with age-matched children from the general population; examined whether PT improves HRQoL; and tested if treatment-related changes in HRQoL were mediated by improvements in ADHD, parent efficacy, and family stress. Method: Parents of 164 children age 3–7 years with an ADHD diagnosis participated in a randomized controlled trial comparing the New Forest Parenting Programme and treatment as usual. Measures of HRQoL, ADHD, parent efficacy, and family stress were completed at baseline, posttreatment, and 36-week follow-up. Child baseline HRQoL was compared with two general population-based reference groups. PT effects were analyzed using linear models and mediation analyses. Results: Preschoolers with ADHD had lower HRQoL than the reference groups. The New Forest Parenting Programme, but not treatment as usual, was associated with improvement in psychosocial HRQoL at posttreatment (change 2.28, 95% CI [0.78, 3.77]) and at 36-week follow-up (change 2.05, 95% CI [0.56, 3.54]). This difference between treatment arms was not statistically significant. Parent efficacy and family stress scores at posttreatment significantly mediated improvements in HRQoL at 36-week follow-up; ADHD scores at posttreatment did not. Conclusion: ADHD negatively impacts HRQoL in early childhood. PT for ADHD has the potential to improve HRQoL independently of its effects on ADHD symptoms. Clinical trial registration information: A Controlled Study of Parent Training in the Treatment of ADHD in Young Children (D'SNAPP); http://clinicaltrial.gov/; NCT01684644.

AB - Objective: School-age children with attention-deficit/hyperactivity disorder (ADHD) have reduced health-related quality of life (HRQoL), but it is unclear whether this is also true for preschool children. It is unknown whether parent training (PT) improves HRQoL. This study compared HRQoL in preschool children with ADHD with age-matched children from the general population; examined whether PT improves HRQoL; and tested if treatment-related changes in HRQoL were mediated by improvements in ADHD, parent efficacy, and family stress. Method: Parents of 164 children age 3–7 years with an ADHD diagnosis participated in a randomized controlled trial comparing the New Forest Parenting Programme and treatment as usual. Measures of HRQoL, ADHD, parent efficacy, and family stress were completed at baseline, posttreatment, and 36-week follow-up. Child baseline HRQoL was compared with two general population-based reference groups. PT effects were analyzed using linear models and mediation analyses. Results: Preschoolers with ADHD had lower HRQoL than the reference groups. The New Forest Parenting Programme, but not treatment as usual, was associated with improvement in psychosocial HRQoL at posttreatment (change 2.28, 95% CI [0.78, 3.77]) and at 36-week follow-up (change 2.05, 95% CI [0.56, 3.54]). This difference between treatment arms was not statistically significant. Parent efficacy and family stress scores at posttreatment significantly mediated improvements in HRQoL at 36-week follow-up; ADHD scores at posttreatment did not. Conclusion: ADHD negatively impacts HRQoL in early childhood. PT for ADHD has the potential to improve HRQoL independently of its effects on ADHD symptoms. Clinical trial registration information: A Controlled Study of Parent Training in the Treatment of ADHD in Young Children (D'SNAPP); http://clinicaltrial.gov/; NCT01684644.

KW - attention-deficit/hyperactivity disorder

KW - health-related quality of life

KW - parent training

KW - preschool children

UR - http://www.scopus.com/inward/record.url?scp=85089102224&partnerID=8YFLogxK

U2 - 10.1016/j.jaac.2020.04.014

DO - 10.1016/j.jaac.2020.04.014

M3 - Journal article

C2 - 32505701

AN - SCOPUS:85089102224

VL - 60

SP - 734

EP - 744

JO - American Academy of Child and Adolescent Psychiatry. Journal

JF - American Academy of Child and Adolescent Psychiatry. Journal

SN - 0890-8567

IS - 6

ER -