Aarhus University Seal / Aarhus Universitets segl

Angela Fago

  1. 2019
  2. Published

    Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. / Bundgård, Amanda Marie; James, Andrew M; Gruszczyk, Anja V; Martin, Jack ; Murphy, Michael P; Fago, Angela.

    In: Scientific Reports, Vol. 9, No. 1, 2850, 02.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Globin E is a myoglobin-related, respiratory protein highly expressed in lungfish oocytes. / Lüdemann, Julia; Verissimo, Kellen Matos ; Dreger, Kimberley ; Fago, Angela; Schneider, Igor ; Burmester, Thorsten.

    In: Scientific Reports, Vol. 9, No. 1, 280, 01.2019.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    Hypoxia enhances blood O 2 affinity and depresses skeletal muscle O 2 consumption in zebrafish (Danio rerio). / Cadiz, Laura; Bundgaard, Amanda; Malte, Hans; Fago, Angela.

    In: Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology, Vol. 234, 2019, p. 18-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. 2018
  6. Published

    Allosteric mechanisms underlying the adaptive increase in hemoglobin-oxygen affinity of the bar-headed goose. / Jendroszek, Agnieszka; Malte, Hans; Overgaard, Cathrine B; Beedholm, Kristian; Natarajan, Chandrasekhar; Weber, Roy E; Storz, Jay F; Fago, Angela.

    In: The Journal of Experimental Biology, Vol. 221, No. 18, 185470, 09.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Reactions of ferric hemoglobin and myoglobin with hydrogen sulfide under physiological conditions. / Jensen, Birgitte; Fago, Angela.

    In: Journal of Inorganic Biochemistry, Vol. 182, 01.05.2018, p. 133-140.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Molecular basis of hemoglobin adaptation in the high-flying bar-headed goose. / Natarajan, Chandrasekhar; Jendroszek, Agnieszka; Kumar, Amit; Weber, Roy E.; Tame, Jeremy R. H.; Fago, Angela; Storz, Jay F.

    In: P L o S Genetics, Vol. 14, No. 4, e1007331, 04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Suppression of reactive oxygen species generation in heart mitochondria from anoxic turtles : the role of complex I S-nitrosation. / Bundgaard, Amanda; James, Andrew M.; Joyce, William; Murphy, Michael P.; Fago, Angela.

    In: Journal of Experimental Biology, Vol. 221, No. 8, 174391, 04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Divergent and parallel routes of biochemical adaptation in high-altitude passerine birds from the Qinghai-Tibet Plateau. / Zhu, Xiaojia; Guan, Yuyan; Signore, Anthony V.; Natarajan, Chandrasekhar; DuBay, Shane G.; Cheng, Yalin; Han, Naijian; Song, Gang; Qu, Yanhua; Moriyama, Hideaki; Hoffmann, Federico G.; Fago, Angela; Lei, Fumin; Storz, Jay F.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 8, 20.02.2018, p. 1865-1870.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Functional diversification of sea lamprey globins in evolution and development. / Fago, Angela; Rohlfing, Kim; Petersen, Elin E.; Jendroszek, Agnieszka; Burmester, Thorsten.

    In: B B A - Proteins and Proteomics, Vol. 1866, No. 2, 02.2018, p. 283-291.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Hemoglobin polymerization via disulfide bond formation in the hypoxia-tolerant turtle Trachemys scripta : implications for antioxidant defense and O-2 transport. / Petersen, Asbjorn G.; Petersen, Steen V.; Frische, Sebastian; Drakulic, Srdja; Golas, Monika M.; Sander, Bjoern; Fago, Angela.

    In: A J P: Regulatory, Integrative and Comparative Physiology (Online), Vol. 314, No. 1, 01.2018, p. R84-R93.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    Ancestral protein resurrection reveals mutational pathways and functional mechanisms of hemoglobin adaption. / Storz, Jay F.; Natarajan, Chandrasekhar; Signore, Anthony V.; Hoffmann, Federico G.; Tame, Jeremy R.H.; Weber, Roy E.; Fago, Angela.

    2018. Session 5 Abstract from XXth International Conference on Oxygen Binding and Sensing Proteins, Barcelona, Spain.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  14. Published

    Investigating the molecular basis of a unique mode of allosteric regulatory control : bicarbonate sensitivity of crocodilian hemoglobin. / Natarajan, C; Hoffmann, Federico G.; Signore, Anthony V.; Weber, Roy E.; Fago, Angela; Storz, Jay.

    2018. P27 Poster session presented at XXth International Conference on Oxygen Binding and Sensing Proteins, Barcelona, Spain.

    Research output: Contribution to conferencePosterResearch

  15. 2017
  16. Published

    Interactions of zebrafish Cytoglobins with oxygen and nitric oxide. / Amdahl, Matthew B.; Petersen, Elin; Corti, Paola; Sparacino-Watkins, Courtney; Fago, Angela; Gladwin, Mark T.; Tejero, Jesus.

    In: Free Radical Biology & Medicine, Vol. 112, No. Supplement 1, 11.2017, p. 19-19.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  17. Published

    The Greenland shark Somniosus microcephalus -Hemoglobins and ligand-binding properties. / Russo, Roberta; Giordano, Daniela; Paredi, Gianluca; Marchesani, Francesco; Milazzo, Lisa; Altomonte, Giovanna; Del Canale, Pietro; Abbruzzetti, Stefania; Ascenzi, Paolo; Di Prisco, Guido; Viappiani, Cristiano; Fago, Angela; Bruno, Stefano; Smulevich, Giulietta; Verde, Cinzia.

    In: P L o S One, Vol. 12, No. 10, e0186181, 12.10.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Functional roles of globin proteins in hypoxia-tolerant ectothermic vertebrates. / Fago, Angela.

    In: Journal of Applied Physiology, Vol. 123, No. 4, 10.2017, p. 926-934.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Regulation of blood oxygen transport in hibernating mammals. / Revsbech, Inge G.; Fago, Angela.

    In: Journal of Comparative Physiology B: Biochemical, Systems, and Environmental Physiology, Vol. 187, No. 5-6, 07.2017, p. 847-856.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin. / Kumar, Amit; Natarajan, Chandrasekhar; Moriyama, Hideaki; Witt, Christopher C.; Weber, Roy E.; Fago, Angela; Storz, Jay F.

    In: Molecular Biology and Evolution, Vol. 34, No. 5, 05.2017, p. 1240-1251.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    A comparison of blood nitric oxide metabolites and hemoglobin functional properties among diving mammals. / Fago, Angela; Parraga, Daniel Garcia; Petersen, Elin E; Kristensen, Niels; Giouri, Lea; Jensen, Frank B.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 205, 03.2017, p. 35-40.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Repeated Prolonged Exercise Decreases Maximal Fat Oxidation in Older Men. / Morville, Thomas; Rosenkilde, Mads; Munch-Andersen, Thor; Andersen, Peter Riis; Kjær Groenbæk, Katja; Helbo, Signe ; Kristensen, Marianne; Vigelsø Hansen, Andreas; Mattsson, Nick; Rasmusen, Hanne Kruuse; Guadalupe Grau, Amelia; Fago, Angela; Neigaard Hansen, Christina; Twelkmeyer, Brigitte; Løvind Andersen, Jesper; Dela, Flemming; Wulff Helge, Jørn.

    In: Medicine and Science in Sports and Exercise, Vol. 49, No. 2, 02.2017, p. 308-316.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published
  24. Published

    O2 binding and CO2 sensitivity in haemoglobins of subterranean African mole rats. / Weber, Roy E.; Jarvis, Jennifer U. M.; Fago, Angela; Bennett, Nigel C.

    In: Journal of Experimental Biology, Vol. 220, No. 21, 2017, p. 3939-3948.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published
  26. Published
  27. 2016
  28. Published

    The roles of tissue nitrate reductase activity and myoglobin in securing nitric oxide availability in deeply hypoxic crucian carp. / Hansen, Marie Niemann; Lundberg, Jon O; Filice, Mariacristina; Fago, Angela; Christensen, Nanna Martinus G; Jensen, Frank B.

    In: The Journal of Experimental Biology, Vol. 219, No. Pt 24, 15.12.2016, p. 3875-3883.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    The Staphylococcus aureus Protein IsdH Inhibits Host Hemoglobin Scavenging to Promote Heme Acquisition by the Pathogen. / Saederup, Kirstine Lindhardt; Stødkilde-Jørgensen, Kristian; Graversen, Jonas Heilskov; Dickson, Claire F.; Etzerodt, Anders; Hansen, Soren Werner Karlskov; Fago, Angela; Gell, David; Andersen, Christian Brix Folsted; Moestrup, Soren Kragh.

    In: Journal of Biological Chemistry, Vol. 291, No. 46, 11.11.2016, p. 23989-23998.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Predictable convergence in hemoglobin function has unpredictable molecular underpinnings. / Natarajan, Chandrasekhar; Hoffmann, Federico G; Weber, Roy E; Fago, Angela; Witt, Christopher C; Storz, Jay F.

    In: Science, Vol. 354, No. 6310, 21.10.2016, p. 336-339.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    Oxygen-Binding Characteristics of Hemoglobins from Hypoxia and Hypercapnia Tolerant African Mole Rats. / Weber, Roy E.; Jarvis, Jennifer U. M ; Fago, Angela; Bennett, Nigel C.

    2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  32. Published

    Students' motivation toward laboratory work in physiology teaching. / Dohn, Niels Bonderup; Fago, Angela; Overgaard, Johannes; Madsen, Peter Teglberg; Malte, Hans.

    In: Advances in Physiology Education, Vol. 40, No. 3, 09.2016, p. 313-318.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  33. Published

    Bohr effect and temperature sensitivity of hemoglobins from highland and lowland deer mice. / Jensen, Birgitte; Storz, Jay F; Fago, Angela.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 195, 05.2016, p. 10-14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Constraints on mutational pathways of hemoglobin evolution. / Kumar, Amit; Natarajan, Chandrasekhar; Moriyama, Hideaki; Witt, Christopher C.; Weber, Roy E.; Fago, Angela; Storz, Jay.

    2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  35. Published

    Functional analysis of Steller’s sea cow (Hydrodamalis gigas) hemoglobin provides new insights to cold adaptation. / Signore, Anthony V.; Fago, Angela; Weber, Roy E.; Morrison, Phillip R.; Brauner, Colin J; Campbell, Kevin L.

    2016. Abstract from Oxygen Binding and Sensing Proteins Conference 2016 , .

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  36. Published

    Haemoglobin adaptations to subterranean burrows: Lessons from African mole rats. SEB 2016 Conference, Brighton, UK. / Weber, Roy E.; Jarvis, Jennifer U. M ; Fago, Angela; Bennett, Nigel C.

    2016. 61-61.

    Research output: Contribution to conferencePosterResearch

  37. Published

    Regulation of oxygen transport in hibernating mammals. / Revsbech, Inge Grønvall; Evans, Alina L; Fröbert, Ole; Malte, Hans; Tufts, Danielle M.; F. Storz, Jay; Fago, Angela.

    2016. Abstract from 15th International Hibernation Symposium, Las Vegas, USA, Las Vegas, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  38. Published

    Roles of sulfide and thiol metabolites in brown bear hibernation. / Fago, Angela; Revsbech, Inge Grønvall; Shen, Xinggui; Kevil, Christopher G.; Evans, Alina L; Fröbert, Ole.

    2016. Abstract from 15th International Hibernation Symposium, Las Vegas, USA, Las Vegas, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  39. Published

    The mechanistic basis of hemoglobin adaptation in the high-flying barheaded goose: insights from ancestral protein resurrection. / Natarajan, Chandrasekhar; Kumar, Amit; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela; Storz, Jay F.

    2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  40. Published

    The molecular basis of convergence in hemoglobin function in high-altitude Andean birds. / Storz, Jay; Natarajan, Chandrasekhar; Witt, Christopher C.; Weber, Roy E.; Fago, Angela.

    2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  41. 2015
  42. Published

    Convergent Evolution of Hemoglobin Function in High-Altitude Andean Waterfowl Involves Limited Parallelism at the Molecular Sequence Level. / Natarajan, Chandrasekhar; Projecto-Garcia, Joana; Moriyama, Hideaki; Weber, Roy E; Muñoz-Fuentes, Violeta; Green, Andy J; Kopuchian, Cecilia; Tubaro, Pablo L; Alza, Luis; Bulgarella, Mariana; Smith, Matthew M; Wilson, Robert E; Fago, Angela; McCracken, Kevin G; Storz, Jay F.

    In: P L o S Genetics, Vol. 11, No. 12, e1005681, 04.12.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  43. Published

    Contribution of a mutational hot spot to hemoglobin adaptation in high-altitude Andean house wrens. / Galen, Spencer C.; Natarajan, Chandrasekhar; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela; Benham, Phred M.; Chavez, Andrea N.; Cheviron, Zachary A.; Storz, Jay F.; Witt, Christopher C.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 45, 10.11.2015, p. 13958-13963.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  44. Published

    Oxygenation properties and isoform diversity of snake hemoglobins. / Storz, Jay F.; Natarajan, Chandrasekhar; Moriyama, Hideaki; Hoffmann, Federico G.; Wang, Tobias; Fago, Angela; Nielsen, Hans Malte; Overgaard, Johannes; Weber, Roy E.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 309, No. 9, 02.11.2015, p. 1178-1191.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  45. Published

    Regulation of hemoglobin oxygen affinity in hibernating animals. / Fago, Angela; Revsbech, I. G.; Damsgaard, C.; Tufts, Danielle M.; Projecto-Garcia, J.; Hoffmann, Federico G.; Moriyama, H.; Frobert, O.; Storz, Jay F.; Weber, R. E.

    In: Acta Physiologica (Online), Vol. 215, 09.2015, p. 50-51.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  46. Published

    A globin domain in a neuronal transmembrane receptor of Caenorhabditis elegans and Ascaris suum. / Tilleman, Lesley; Germani, Francesca; Henau, Sasha De; Helbo, Signe; Desmet, Filip; Berghmans, Herald; Van Doorslaer, Sabine; Hoogewijs, David; Schoofs, Liliane; Braeckman, Bart B.; Moens, Luc; Fago, Angela; Dewilde, Sylvia.

    In: Journal of Biological Chemistry, Vol. 290, No. 16, 2015, p. 10336-10352.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  47. Published

    Causes of parallel biochemical adaptation: Insights from hemoglobins of high-altitude vertebrates. / Storz, Jay; Natarajan, Chandrasekhar; Witt, Christopher C.; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela.

    2015. Abstract from 2014 APS Intersociety Meeting: Comparative Approaches to Grand Challenges in Physiology , San Diego, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  48. Published

    Comparative genomics, multigene families, and physiological evolution. / Storz, Jay; Natarajan, Chandrasekhar; Hoffmann, Frederico G; Opazo, Juan C; Witt, Christopher C.; Berenbrink, Michael; Weber, Roy E.; Fago, Angela.

    2015. Abstract from SEB Annual Main Meeting, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. Submitted

    Comparison of circulating hydrogen sulfide and nitric oxide metabolites and their potential roles in brown bean hibernation. / Revsbech, Inge Grønvall; Shen, Xinggui; Chakravarti, Ritu; B. Jensen, Frank; Thiel, Bonnie; Fröbert, Ole; Stuehr, Dennis J; Kevil, Christopher G.; Fago, Angela.

    In: Nitric Oxide: Biology and Chemistry, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference articleResearchpeer-review

  50. Published

    Comparison of key enzymatic activities in red blood cells from summer active and winter hibernating brown bears. / Russo, Giulia; Polese, Gianluca; Evans, Alina; Frobert, Ole; Fago, Angela.

    2015. Abstract from SEB Annual Main Meeting, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  51. Published

    Effects of an 8-weeks erythropoietin treatment on mitochondrial and Whole body fat oxidation capacity during exercise in healthy males. / Guadalupe Grau, Amelia; Plenge, Ulla; Bønding, Signe Helbo; Kristensen, Marianne ; Andersen, Peter Riis; Fago, Angela; Belhage, Bo; Dela, Flemming; Helge, Jørn Wulff.

    In: Journal of Sports Sciences, Vol. 33, No. 6, 2015, p. 570-578.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  52. Published

    Epistasis constrains mutational pathways of hemoglobin adaptation in high-altitude pikas. / Tufts, Danielle M.; Natarajan, Chandrasekhar; Revsbech, Inge Grønvall; Projecto-Garcia, Joana; Hoffmann, Federico D.; Weber, Roy E.; Fago, Angela; Moriyama, H.; Storz, Jay F.

    In: Molecular Biology and Evolution, Vol. 32, No. 2, 2015, p. 287-298.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  53. Published

    Genetically based low oxygen affinities of felid hemoglobins: lack of biochemical adaptation to high-altitude hypoxia in the snow leopard. / Janecka, Jan E; Nielsen, Simone Schandorf Elstrøm; Andersen, Sidsel D; Hoffmann, Federico G; Weber, Roy E.; Anderson, Trevor; Storz, Jay F; Fago, Angela.

    In: Journal of Experimental Biology, Vol. 218, 2015, p. 2402-2409.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  54. Published

    Hypoxia tolerance, nitric oxide, and nitrite: Lessons from extreme animals. / Fago, Angela; B. Jensen, Frank.

    In: Physiology, Vol. 30, No. 2, 2015, p. 116-126.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  55. Published

    Inhibition of mitochondrial complex I activity protects the heart of anoxic turtles against oxidative damage. / Bundgård, Amanda Marie; Chouchani, Edward T; James, Andrew M; Bright, Thomas; Murphy, Mike; Fago, Angela.

    2015. Abstract from SEB Annual Main Meeting, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  56. Published

    Inhibitory effects of nitrite on the reactions of bovine carbonic anhydrase II with CO2 and bicarbonate consistent with zinc-bound nitrite. / Nielsen, Per; Fago, Angela.

    In: Journal of Inorganic Biochemistry, Vol. 149, 2015, p. 6-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  57. Published

    Intraspecific polymorphism, interspecific divergence, and the origins of function-altering mutaiton in deer mouse hemoglobin. / Natarajan, Chandrasekhar; Hoffmann, Federico G.; Lanier, Hayley C; Wolf, Cole J.; Cheviron, Zachary A.; Spangler, Matthew L; Weber, Roy E.; Fago, Angela; F. Storz, Jay.

    In: Molecular Biology and Evolution, Vol. 32, No. 4, 2015, p. 978-997.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  58. Published

    Kinetic properties and heme pocket structure of two domains of the polymeric hemoglobin of Artemia in comparison with the native molecule. / Borhani, Heshmat Akbari; Berghmans, Herald; Trashin, Stanislav; De Wael, Karolien; Fago, Angela; Moens, Luc; Habibi-Rezaei, Mehran; Dewilde, Sylvia.

    In: BBA General Subjects, Vol. 1854, No. 10, 2015, p. 1307-1316.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  59. Published

    Molecular mechanisms regulating the cardiovascular system of extreme vertebrates. / Fago, Angela; Jensen, Frank B.

    2015. Abstract from SEB Annual Main Meeting, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  60. Published

    Myoglobin oxygenation and autoxidation in three reptilian species. / Helbo, Signe; Bundgård, Amanda Marie; Fago, Angela.

    In: Comparative Biochemistry and Physiology - Part A: Comparative Physiology, Vol. 187, 2015, p. 8-12.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  61. Published

    Oxygen binding functions of hemoglobins of African mole rats inhabiting hypoxic and hypercapnic burrows. / Weber, Roy E.; Jarvis, Jennifer U. M ; Fago, Angela; Bennett, Nigel C.

    2015. Abstract from SEB Annual Main Meeting, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  62. Published

    The hemoglobins of the Greenland shark Somniosus microcephalus. / Verde, Cinzia; Giordano, Daniela; Russo, Roberta; Altomonte, Giovanna; Viappiani, Cristiano; Di Prisco, Guido; Bruno, Stefano; Fago, Angela.

    2015. Abstract from SEB Annual Main Meeting, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  63. 2014
  64. Published

    High blood oxygen affinity in the air-breathing swamp eel Monopterus albus. / Damsgaard, Christian; Findorf, Inge; Helbo, Signe; Kocagoz, Yigit; Buchanan, Rasmus; Huong, Do Thi Thanh; Weber, Roy E.; Fago, Angela; Bayley, Mark; Wang, Tobias.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 178, 12.2014, p. 102-108.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  65. Published

    Integrating Evolutionary and Functional Tests of Adaptive Hypotheses : A Case Study of Altitudinal Differentiation in Hemoglobin Function in an Andean Sparrow, Zonotrichia capensis. / Cheviron, Zachary A; Natarajan, Chandrasekhar; Projecto-Garcia, Joana; Eddy, Douglas K; Jones, Jennifer; Carling, Matthew D; Witt, Christopher C; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela; Storz, Jay F.

    In: Molecular Biology and Evolution, 18.08.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  66. Published

    Hydrogen sulfide and nitric oxide metabolites in the blood of free-ranging brown bears and their potential roles in hibernation. / Revsbech, Inge G; Shen, Xinggui; Chakravarti, Ritu; Jensen, Frank B; Thiel, Bonnie; Evans, Alina L; Kindberg, Jonas; Fröbert, Ole; Stuehr, Dennis J; Kevil, Christopher G; Fago, Angela.

    In: Free Radical Biology & Medicine, Vol. 73C, 05.06.2014, p. 349-357.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  67. Published

    Causes and consequences of nonadditive mutational effects in the functional evolution of vertebrate hemoglobins. / Storz, Jay; Natarajan, Chandrasekhar; Tufts, Danielle M.; Projecto-Garcia, Joana; Witt, Christopher C.; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela.

    2014. Abstract from XVIII Conference on Oxygen-Binding and Sensing Proteins, Sheffield, United Kingdom.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  68. Published

    Enthalpic partitioning of the reduced temperature sensitivity of O2 binding in bovine hemoglobin. / Weber, Roy E; Fago, Angela; Campbell, Kevin L.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 176, 2014, p. 20-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  69. Published

    GLB-33: when a globin hooks up with a G-protein coupled receptor. / Vangheel, Matthew; Henau, Sasha De; Tilleman, Lesley; Germani, Francesca; Helbo, Signe; Desmet, Filip; Van Doorslaer, Sabine; Hoogewijs, David; Schoofs, Liliane; Fago, Angela; Moens, Luc; Dewilde, Sylvia; Braeckman, Bart B.

    2014. Poster session presented at XVIII Conference on Oxygen-Binding and Sensing Proteins, Sheffield, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  70. Published

    Mechanisms for suppression of oxygen delivery and consumption in hibernating brown bears. / Fago, Angela; Revsbech, Inge Grønvall; Shen, Xinggui; Evans, Alina; Fröbert, Ole; Kevil, Christopher G.

    2014. Abstract from 2014 APS Intersociety Meeting: Comparative Approaches to Grand Challenges in Physiology , San Diego, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  71. Published

    Molecular and functional evolution of hemoglobin in sirenians. / Signore, Anthony V.; Paijmans, Johanna; Hofreiter, Michael; Weber, Roy E.; Fago, Angela; Campbell, Kevin L.

    2014. Abstract from XVIII Conference on Oxygen-Binding and Sensing Proteins, Sheffield, United Kingdom.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  72. Published

    Oxygen-linked s-nitrosation in fish myoglobins : A cysteine-specific tertiary allosteric effect. / Helbo, Signe; Gow, Andrew J. ; Jamil, Anna Jamil; Howes, Barry D.; Fago, Angela.

    In: P L o S One, Vol. 9, No. 5, e97012, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  73. 2013
  74. Published

    Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds. / Projecto-Garcia, J.; Natarajan, C.; Moriyama, H.; Weber, R.E.; Fago, A.; Cheviron, Z.A.; Dudley, R.; McGuire, J.A.; Witt, C.C.; Storz, J.F.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 51, 17.12.2013, p. 20669-20674.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  75. Published

    Decrease in the red cell cofactor 2,3-diphosphoglycerate increases hemoglobin oxygen affinity in the hibernating brown bear Ursus arctos. / Revsbech, Inge G.; Malte, Hans; Frøbert, Ole; Evans, Alina; Blanc, Stéphane; Josefsson, Johan; Fago, Angela.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 304, 2013, p. R43-R49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  76. Published

    Deer mouse hemoglobin exhibits a lowered oxygen affinity owing to mobility of the E helix. / Inoguchi, Noriko; R. Oshlo, Jake; Natarajan, C.; Weber, Roy E.; Fago, Angela; F. Storz, Jay; Moriyama, Hideaki.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, Vol. 69, No. 4, 2013, p. 393-398.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  77. Published

    Epistasis among adaptive mutations in deer mouse hemoglobin. / Natarajan, Chandrasekhar; Inoguchi, Noriko; Weber, Roy E; Fago, Angela; Moriyama, Hideaki; Storz, Jay F.

    In: Science, Vol. 340, No. 6138, 2013, p. 1324-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  78. Published

    Expression patterns and adaptive functional diversity of vertebrate myoglobins. / Helbo, Signe; Weber, Roy E.; Fago, Angela.

    In: B B A - Proteins and Proteomics, Vol. 1834, No. 9, 2013, p. 1832-1839.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

  79. Published

    Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges. / Revsbech, Inge G.; Tufts, Danielle M.; Projecto-Garcia, Joana ; Moriyama, Hideaki; Weber, Roy E.; Storz, Jay F.; Fago, Angela.

    In: Journal of Experimental Biology, Vol. 216, 2013, p. 4264-4271.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  80. Published

    Hemoglobin isoform differentiation and allosteric regulation of oxygen binding in the turtle, Trachemys scripta. / Damsgaard, Christian; Storz, Jay F.; Hoffmann, Federico G. ; Fago, Angela.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 305, No. 8, 2013, p. R961-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  81. Published

    Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in dwarf caiman hemoglobin. / Weber, Roy E; Fago, Angela; Malte, Hans; Storz, Jay F; Gorr, Thomas A.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 305, No. 3, 2013, p. R300-R312.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  82. Published

    Molecular and Functional Characterisation of Hemocyanin of the Giant African Millipede Archispirostreptus gigas. / Damsgaard, Christian; Fago, Angela; Hagner-Holler, Silke ; Malte, Hans; Burmester, Thosten; Weber, Roy E.

    In: Journal of Experimental Biology, Vol. 216, 2013, p. 1616-1623.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  83. Published

    Myoglobin-dependent O2 consumption of the hypoxic trout heart. / Helbo, Signe; Fago, Angela; Gesser, Hans.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 165, No. 1, 2013, p. 40-45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  84. Published

    Oxygen binding to partially nitrosylated hemoglobin. / Fago, Angela; Crumbliss, Alvin L. ; Hendrich, Michael P. ; Pearce, Linda L. ; Peterson, Jim; Henkens, Robert; Bonaventura, Celia.

    In: B B A - Proteins and Proteomics, Vol. 1834, No. 9, 2013, p. 1894-1900.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  85. Published

    Phenotypic plasticity in blood-oxygen transport in highland lowland deer mice. / Tufts, Danielle M. ; Revsbech, Inge G.; Cheviron, Zachary A.; Weber, Roy E.; Fago, Angela; Storz, Jay F. .

    In: Journal of Experimental Biology, Vol. 216, 2013, p. 1167-1173.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  86. 2012
  87. Published

    A globin domain in a neuronal transmembrane receptor in Caenorhabditis elegans. / Tilleman, Lesley ; Germani, Francesca ; De Hau, Sasha ; Helbo, Signe; Desmet, Fillip ; Van Doorslaer, Sabine ; Schoofs, Liliane ; Braeckman, Bart B. ; Fago, Angela; Moens, Luc ; Dewilde, Sylvia .

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  88. Published

    Allosteric Modulation of Oxygen Affinity in Dwarf Caiman Hemoglobin that Lacks Conventional Proton and Anion Binding Sites. / Weber, Roy E.; Fago, Angela; Malte, H.; Storz, Jay ; Gorr, Thomas A. .

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  89. Published

    Allosteric effects and enzymatic functions of fish myoglobins in the protection against hypoxia. / Fago, Angela; Helbo, Signe.

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  90. Published

    Allosteric regulation of O2 binding in hemocyanin of the millipede, Archispirostreptus gigas, and its molecular underpinnings. / Damsgaard, Christian; Fago, Angela; Hagner-Holler, Silke; Malte, H.; Burmester, Thorstein ; Weber, Roy E.

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  91. Published

    Decrease in red cell cofactor 2,3-diphosphoglycerate causes an increase in hemoglobin oxygen affinity in the hibernating brown bear Ursus arctos. / Revsbech, Inge Grønvall; Fröbert, Ole ; Evans, Alina; Blanc, Stéphanie; Josefsson, Johan; Malte, H.; Fago, Angela.

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  92. Published

    Hibernating golden mantled ground squirrel Spermophilus lateralis: Temperature rather than 2,3-DPG underlies increased hemoglobin O2 affinity. / Revsbech, Inge Grønvall; Weber, Roy E.; Storz, Jay F; Fago, Angela.

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  93. Published

    Nitrite reductase activities and O2 binding of myoglobins from whales with different diving capacities. / Helbo, Signe; Fago, Angela.

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  94. Published

    Nonadditive interaction effects between hemoglobin mutations: evolutionary implications. / Natarajan , C; Moriyama , H; Weber, Roy E.; Fago, Angela.

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  95. Published

    Parallel evolution of hemoglobin function in Andean hummingbirds. / Projecto-Garcia, Joana; Natarajan, Chandrasekhar ; Witt, Christopher C. ; Cheviron, Zachary A. ; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela; Storz, Jay F. .

    2012. Abstract from XVII International Conference on Oxygen Binding and Sensing Proteins, Parma, Italy.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  96. Published

    Oxygen binding by dwarf caiman haemoglobin that lacks key allosteric effector-binding sites. / Weber, Roy E.; Fago, Angela; Malte, H.; Storz, Jay F.; Gorr, Thomas A.

    2012. Abstract from Proc. Society of Experimantal Biology, Annual Meeting, Salzburg, .

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  97. Published

    Functional properties of myoglobins from five whale species with different diving capacities. / Helbo, Signe; Fago, Angela.

    In: Journal of Experimental Biology, Vol. 215, 06.06.2012, p. 3403-3410.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  98. Published

    Integrating nitric oxide, nitrite and hydrogen sulfide signaling in the physiological adaptions to hypoxia: A comparative approach. / Fago, Angela; B. Jensen, Frank; Tota, Bruno; Feelisch, Martin; R. Olsen, Kenneth; Helbo, Signe; Lefevre, Sjannie; Mancardi, Daniele; Palumbo, Anna; K. Sandvik, Guro; Skovgaard, Nini.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 162, No. 1, 23.01.2012, p. 1-6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  99. Published

    Insights into the anomalous heme pocket of rainbow trout myoglobin. / D. Howes, Barry; Helbo, Signe; Fago, Angela; Smulevich, Giulietta.

    In: Journal of Inorganic Biochemistry, Vol. 109, 18.01.2012, p. 1-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  100. Published

    Circulating nitric oxide metabolites and cardiovascular changes in the turtle Trachemys scripta during normoxia, anoxia and reoxygenation. / Jacobsen, Søren B; Hansen, Marie N; Jensen, Nini Skovgaard; Wang, Tobias; Fago, Angela.

    In: Journal of Experimental Biology, Vol. 215, 2012, p. 2560-2566.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  101. Published

    Functional differentiation of myoglobin isoforms in hypoxia-tolerant carp indicates tissue-specific protective roles. / Helbo, Signe; Dewilde, Sylvia; Williams, Daryl R.; Berghmans, Herald; Berenbrink, Michael; Cossins, Andrew R.; Fago, Angela.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 302, 2012, p. R693-R701.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  102. Published

    Nitrite reductase activities of myoglobins from five whale species with distinct diving capacities. / Helbo, Signe; Fago, Angela.

    2012. Abstract from Seventh International Conference on the Biology, Chemistry and Therapeutic Application of Nitric Oxide, Edinburgh, United Kingdom.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  103. Published

    Oxygenation properties and oxidation rates of mouse hemoglobins that differ in reactive cysteine content. / Storz, J.F.; Weber, Roy E.; Fago, Angela.

    In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, Vol. 161, 2012, p. 265-270.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  104. 2011
  105. Published

    A Membrane-Bound Vertebrate Globin. / Blank, Miriam; Wollberg, Jessica; Gerlach, Frank; Reimann, Katja; Roesner, Anja; Hankeln, Thomas ; Fago, Angela; Weber, Roy E.; Burmester, Thorsten.

    In: P L o S One, Vol. 6, No. 9, 20.09.2011, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  106. Published

    Enhancing effects of acetazolamide on neuronal activity correlate with enhanced visual processing ability in humans. / Aamand, Rasmus; Skewes, Joshua; Møller, Arne; Fago, Angela; Roepstorff, Andreas.

    In: Neuropharmacology, Vol. 61, No. 5-6, 29.06.2011, p. 900-908.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  107. Published

    Temperature but not intracellular 2,3-DPG underlies increased haemoglobin-O2 affinity in the hibernating golden mantled ground squirrel Spermophilus lateralis. / Revsbech, Inge Grønvall; Weber, Roy E.; Storz, Jay F.; Fago, Angela.

    2011. Abstract from Society for Experimental Biology, SEB Annual Meeting 2011, Glasgow, United Kingdom.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  108. Published

    Allosteric modulation by S-nitrosation in the low-O2 affinity myoglobin from rainbow trout. / Helbo, Signe; Fago, Angela.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 300, No. 1, 01.01.2011, p. R101-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  109. Published

    Altitudinal differentiation in hemoglobin function in birds and small mammals. / F. Storz, Jay; Projecto-Garcia, Joana; A. Cheviron, Zachary; Natarajan, Chandrasekhar; Moriyama, Hideaki; Weber, Roy E.; Fago, Angela.

    2011. Abstract from International Conference for Comparative Physiology and Biochemistry (ICCPB2011), Nagoya, Japan.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

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