Anni Hangaard Andersen

2004

Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding

Frøhlich, R. F., Andersen, F. F., Westergaard, O., Andersen, A. H. & Knudsen, B. R., 2004, In: Journal of Molecular Biology. 336, p. 93-103 11 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

30 Citations (Scopus)

The tranducer domain is important for clamp operation in human DNA topoisomerase II alpha

Østergaard, V. H., Bjergbæk, L., Skouboe, C., Giangiacomo, L., Knudsen, B. R. & Andersen, A. H., 2004, In: Journal of Biological Chemistry. 279, p. 1684-1691 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

24 Citations (Scopus)

Vi mangler medietræning

Andersen, A. H., 2004, In: Dansk Magisterblad. 14

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

2003

A human topoisomerase IIα heterodimer with only one ATP binding site can go through successive catalytic cycles

Skouboe, C., Bjergbæk, L., Østergaard, V., Larsen, M. K., Knudsen, B. R. & Andersen, A. H., 2003, In: Journal of Biological Chemistry. 278, p. 5768-5774

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

29 Citations (Scopus)

Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity

Chikamori, K., Grabowski, D. R., Kinter, M., Willard, B. B., Yadav, S., Aebersold, R. H., Bukowski, R. M., Hickson, I. D., Andersen, A. H., Ganapathi, R. & Ganapathi, M. K., 2003, In: Journal of Biological Chemistry. 278, p. 12696-12702 7 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

54 Citations (Scopus)

Recombinogenic flap ligation mediated by human topoisomerase I

Andersen, F. F., Andersen, K. E., Kusk, M., Frøhlich, R. F., Westergaard, O., Andersen, A. H. & Knudsen, B. R., 2003, In: Journal of Molecular Biology.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

9 Citations (Scopus)

RecQ helicases and topoisomerase III in cancer and aging

Laursen, L. V., Bjergbæk, L., Murray, J. M. & Andersen, A. H., 2003, In: Biogerontology. 4, p. 275-287 13 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

14 Citations (Scopus)

Role for the fission yeast RecQ helicase in DNA repair in G(2)

Laursen, L. V., Ampatzidou, E., Andersen, A. H. & Murray, J. M., 2003, In: Molecular and Cellular Biology. 23, p. 3692-3705 14 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

63 Citations (Scopus)

2002

Anvendelse af de topologiske kræfter i DNA dobbelthelix'en

Thyssen, A., Andersen, F. F., Olesen, J. R., Knudsen, B. R., Westergaard, O. & Andersen, A. H., 2002.

Research output: Contribution to conference › Poster › Research

Changes in mobility account for camptothecin induced subnuclear relocation of topoisomerase I

Christensen, M. O., Barthelmes, H. U., Feineis, S., Knudsen, B. R., Andersen, A. H., Boege, F. & Mielke, C., 2002, In: Journal of Biological Chemistry. 277, p. 15661-15665 5 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

36 Citations (Scopus)

2001

Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation

Lisby, M., Olesen, J. R., Skouboe, C., Krogh, B. O., Straub, T., Boege, F., Velmurugan, S., Martensen, P. M., Andersen, A. H., Jayaram, M., Westergaard, O. & Knudsen, B. R., 2001, In: Journal of Biological Chemistry. 276, p. 20220-20227 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

49 Citations (Scopus)

Topoisomerase II interacts with hairpin structures formed within human centromeric DNA

Jonstrup, A. T., Andersen, C. L., Wang, Y., Koch, J. & Andersen, A. H., 2001, In: Anticancer Research. 21, 3A, p. 1555 1 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Conference abstract in journal › Research

Uncoupling of topoisomerase-mediated DNA cleavage and religation

Andersen, A. H., Christiansen, K. & Westergaard, O., 2001, Methods in Molecular Biology: Vol. 95: DNA Topoisomerase Protocols, Part II: Enzymology and Drugs. Humana Press Inc, p. 101-107 7 p.

Research output: Contribution to book/anthology/report/proceeding › Book chapter › Research

4 Citations (Scopus)

2000

Communication between the ATPase and cleavage/religation domains of human topoisomerase IIα

Bjergbæk, L., Kingma, P., Nielsen, I. S., Wang, Y., Westergaard, O., Osheroff, N. & Andersen, A. H., 2000, In: Journal of Biological Chemistry. 275, p. 13041-13048 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

41 Citations (Scopus)

Position-specific effect of ribonucleotides on the cleavage activity of human topoisomerase II.

Wang, Y., Thyssen, A., Westergaard, O. & Andersen, A. H., 2000, In: Nucleic Acids Research. 28, 24, p. 4815-21 6 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

16 Citations (Scopus)

1999

Stimulated activity of human topoisomerase IIα and IIβ on RNA containing substrates

Wang, Y., Knudsen, B. R., Bjergbæk, L., Westergaard, O. & Andersen, A. H., 1999, In: Journal of Biological Chemistry. 274, p. 22839-22846 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research

34 Citations (Scopus)

Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIα

Bjergbæk, L., Jensen, S., Westergaard, O. & Andersen, A. H., 1999, In: Journal of Biological Chemistry. 274, p. 26529-26536 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

20 Citations (Scopus)

1998

Characterization of DNA topoisomerase II alpha/beta heterodimers in HeLa cells

Gromova, I., Biersack, H., Jensen, S., Nielsen, O. F., Westergaard, O. & Andersen, A. H., 24 Nov 1998, In: Biochemistry. 37, 47, p. 16645-52 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

10 Citations (Scopus)

1996

Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms

Biersack, H., Jensen, S., Gromova, I., Nielsen, I. S., Westergaard, O. & Andersen, A. H., 6 Aug 1996, In: Proceedings of the National Academy of Sciences (PNAS). 93, 16, p. 8288-93 6 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

47 Citations (Scopus)

Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae

Jensen, S., Andersen, A. H., Kjeldsen, E., Biersack, H., Olsen, E. H. N., Andersen, T. B., Westergaard, O. & Jakobsen, B. K., Jul 1996, In: Molecular and Cellular Biology. 16, 7, p. 3866-77 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

53 Citations (Scopus)

Human DNA topoisomerases II alpha and II beta can functionally substitute for yeast TOP2 in chromosome segregation and recombination

Jensen, S., Redwood, C. S., Jenkins, J. R., Andersen, A. H. & Hickson, I. D., 27 Aug 1996, In: Molecular Genetics and Genomics. 252, 1-2, p. 79-86 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

49 Citations (Scopus)

Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I

Boege, F., Straub, T., Kehr, A., Boesenberg, C., Christiansen, K., Andersen, A. H., Jakob, F. & Köhrle, J., 26 Jan 1996, In: Journal of Biological Chemistry. 271, 4, p. 2262-70 9 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

235 Citations (Scopus)

1995

Proliferation-associated nuclear antigen Ki-S1 is identical with topoisomerase II alpha. Delineation of a carboxy-terminal epitope with peptide antibodies

Boege, F., Andersen, A., Jensen, S., Zeidler, R. & Kreipe, H., Jun 1995, In: American Journal of Pathology. 146, 6, p. 1302-8 7 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

79 Citations (Scopus)

1993

Eukaryotic topoisomerase I-mediated cleavage requires bipartite DNA interaction. Cleavage of DNA substrates containing strand interruptions implicates a role for topoisomerase I in illegitimate recombination

Christiansen, K., Svejstrup, A. B., Andersen, A. H. & Westergaard, O., 5 May 1993, In: Journal of Biological Chemistry. 268, 13, p. 9690-701 12 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

83 Citations (Scopus)

1992

8-methoxycaffeine inhibition of Drosophila DNA topoisomerase II

Tornaletti, S., Andersen, A. H., Christiansen, K. & Pedrini, A. M., 7 May 1992, In: B B A - General Subjects. 1131, 1, p. 30-3 4 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

5 Citations (Scopus)

Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events

Sørensen, B. S., Sinding, J., Andersen, A. H., Alsner, J., Jensen, P. B. & Westergaard, O., 5 Dec 1992, In: Journal of Molecular Biology. 228, 3, p. 778-786 9 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

127 Citations (Scopus)

1991

Drug Stimulated DNA Cleavage Mediated by Cauliflower Topoisomerase II

Sørensen, B. S., Fukata, H., Jensen, P. S., Andersen, A. H., Christiansen, K., Fukasawa, H. & Westergaard, O., Feb 1991, In: Plant Physiology. 95, 2, p. 659-62 4 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

1 Citation (Scopus)

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

Svejstrup, J. Q., Christiansen, K., Gromova, I. I., Andersen, A. H. & Westergaard, O., 5 Dec 1991, In: Journal of Molecular Biology. 222, 3, p. 669-78 10 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

163 Citations (Scopus)

Studies of the topoisomerase II-mediated cleavage and religation reactions by use of a suicidal double-stranded DNA substrate

Andersen, A. H., Sørensen, B. S., Christiansen, K., Svejstrup, J. Q., Lund, K. & Westergaard, O., 15 May 1991, In: Journal of Biological Chemistry. 266, 14, p. 9203-10 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

49 Citations (Scopus)

1990

Characterization of the interaction between topoisomerase II and DNA by transcriptional footprinting

Thomsen, B., Bendixen, C., Lund, K., Andersen, A. H., Sørensen, B. S. & Westergaard, O., 20 Sept 1990, In: Journal of Molecular Biology. 215, 2, p. 237-44 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

61 Citations (Scopus)

Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro

Svejstrup, J. Q., Christiansen, K., Andersen, A. H., Lund, K. & Westergaard, O., 25 Jul 1990, In: Journal of Biological Chemistry. 265, 21, p. 12529-35 7 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

88 Citations (Scopus)

Minimal DNA requirement for topoisomerase II-mediated cleavage in vitro

Lund, K., Andersen, A. H., Christiansen, K., Svejstrup, J. Q. & Westergaard, O., 15 Aug 1990, In: Journal of Biological Chemistry. 265, 23, p. 13856-63 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

31 Citations (Scopus)

1989

Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate

Zechiedrich, E. L., Christiansen, K., Andersen, A. H., Westergaard, O. & Osheroff, N., 25 Jul 1989, In: Biochemistry. 28, 15, p. 6229-36 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

137 Citations (Scopus)

Strand specificity of the topoisomerase II mediated double-stranded DNA cleavage reaction

Andersen, A. H., Christiansen, K., Zechiedrich, E. L., Jensen, P. S., Osheroff, N. & Westergaard, O., 25 Jul 1989, In: Biochemistry. 28, 15, p. 6237-44 8 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

74 Citations (Scopus)

1985

Topoisomerase I has a strong binding preference for a conserved hexadecameric sequence in the promoter region of the rRNA gene from Tetrahymena pyriformis

Andersen, A. H., Gocke, E., Bonven, B. J., Nielsen, O. F. & Westergaard, O., 11 Mar 1985, In: Nucleic Acids Research. 13, 5, p. 1543-57 15 p.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

67 Citations (Scopus)

Anni Hangaard Andersen

Research output

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